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List of works by Benoit R Gauthier

A Simple High Efficiency Intra-Islet Transduction Protocol Using Lentiviral Vectors

scientific article published on 30 June 2015

A new conditional mouse mutant reveals specific expression and functions of connexin36 in neurons and pancreatic beta-cells

scientific article

Adipose mesenchymal stromal cells isolated from type 2 diabetic patients display reduced fibrinolytic activity.

scientific article published on 16 September 2013

Advances in Genetics of Regeneration in Metabesity.

scientific article published on 20 May 2019

Association of childhood type 1 diabetes mellitus with a variant of PAX4: possible link to beta cell regenerative capacity

scientific article published on 15 April 2005

CD14 is an acute-phase protein

scientific article published on April 2004

Characterization of a cholesterol response element (CRE) in the promoter of the cholesteryl ester transfer protein gene: functional role of the transcription factors SREBP-1a, -2, and YY1.

scientific article published on July 1999

Characterization of a novel liver-specific protein/DNA binding site in the human HMG CoA reductase promoter

scientific article published on June 1998

Characterization of two distinct liver progenitor cell subpopulations of hematopoietic and hepatic origins.

scientific article published on 19 May 2006

Cholesteryl ester transfer protein gene expression during differentiation of human preadipocytes to adipocytes in primary culture

scientific article published in February 1999

Corrigendum to "Islet β-Cell Mass Preservation and Regeneration in Diabetes Mellitus: Four Factors with Potential Therapeutic Interest"

scientific article published on 02 June 2019

Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression

scientific article

Dissecting the Brain/Islet Axis in Metabesity

scientific article published on 08 May 2019

Dopamine modulates von Willebrand factor secretion in endothelial cells via D2-D4 receptors

scientific article

Dual Trade of Bcl-2 and Bcl-xL in islet physiology: balancing life and death with metabolism secretion coupling

scientific article published on January 2013

Endoplasmic Reticulum Stress Links Oxidative Stress to Impaired Pancreatic Beta-Cell Function Caused by Human Oxidized LDL

scientific article

GATA6 Controls Insulin Biosynthesis and Secretion in Adult ß cell.

scientific article published on 20 December 2017

Hepatic lipase affects both HDL and ApoB-containing lipoprotein levels in the mouse

scientific article published in June 1998

Hepatic nuclear factor 1alpha (HNF1alpha) dysfunction down-regulates X-box-binding protein 1 (XBP1) and sensitizes beta-cells to endoplasmic reticulum stress

scientific article

Hepatic nuclear factor-3 (HNF-3 or Foxa2) regulates glucagon gene transcription by binding to the G1 and G2 promoter elements

scientific article

Human Omental Mesothelial Cells Impart an Immunomodulatory Landscape Impeding B- and T-Cell Activation

scientific article published on 25 May 2022

Immunohistochemical assessment of Pax8 expression during pancreatic islet development and in human neuroendocrine tumors

scientific article

In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice

scientific article

Inadequate control of thyroid hormones sensitizes to hepatocarcinogenesis and unhealthy aging

scientific article published on 13 September 2019

Islet β-Cell Mass Preservation and Regeneration in Diabetes Mellitus: Four Factors with Potential Therapeutic Interest

scientific article published on 5 August 2012

LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus.

scientific article published on 16 April 2018

Levothyroxine enhances glucose clearance and blunts the onset of experimental type 1 diabetes mellitus in mice.

scientific article published on 11 August 2017

Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets

scientific article published in October 2006

MicroRNAs: 'ribo-regulators' of glucose homeostasis

scientific article published in January 2006

Molecular Modelling of Islet β-Cell Adaptation to Inflammation in Pregnancy and Gestational Diabetes Mellitus

scientific article published on 06 December 2019

PARP-1 and cytokine-mediated β-cell damage: a nick in the Okamoto model?

scientific article published on 08 May 2012

PAX4 Defines an Expandable β-Cell Subpopulation in the Adult Pancreatic Islet

scientific article

PAX4 preserves endoplasmic reticulum integrity preventing beta cell degeneration in a mouse model of type 1 diabetes mellitus.

scientific article published on 26 January 2016

PDX1 deficiency causes mitochondrial dysfunction and defective insulin secretion through TFAM suppression

scientific article

Pancreatic alpha-cell mass in the early-onset and advanced stage of a mouse model of experimental autoimmune diabetes

scientific article published on 02 July 2019

Pancreatic insulin content regulation by the estrogen receptor ER alpha

scientific article

Pax8 Detection in Well-Differentiated Pancreatic Endocrine Tumors

scientific article published on 01 December 2011

Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cells.

scientific article

Synaptotagmins bind calcium to release insulin.

scientific article published on 19 August 2008

Targeting LRH-1/NR5A2 to treat type 1 diabetes mellitus

scientific article published on 22 May 2018

Targeting pancreatic expressed PAX genes for the treatment of diabetes mellitus and pancreatic neuroendocrine tumors.

scientific article published on 14 November 2016

The Diabetes-Linked Transcription Factor PAX4: From Gene to Functional Consequences

scientific article published on 09 March 2017

The Fas pathway is involved in pancreatic beta cell secretory function

scholarly article

The T1D-associated lncRNA Lnc13 modulates human pancreatic β cell inflammation by allele-specific stabilization of STAT1 mRNA

scientific article published on 13 April 2020

The cannabinoid ligand LH-21 reduces anxiety and improves glucose handling in diet-induced obese pre-diabetic mice.

scientific article

The diabetes-linked transcription factor PAX4 promotes {beta}-cell proliferation and survival in rat and human islets

scientific article

The diabetes-linked transcription factor Pax4 is expressed in human pancreatic islets and is activated by mitogens and GLP-1.

scientific article published on 7 November 2007

The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects {beta}-cells against stress-induced apoptosis

scientific article published on 2 May 2011

The paired homeodomain transcription factor Pax-2 is expressed in the endocrine pancreas and transactivates the glucagon gene promoter.

scientific article

The pancreatic beta-cell-specific transcription factor Pax-4 inhibits glucagon gene expression through Pax-6.

scientific article

The transcription factor PAX4 acts as a survival gene in INS-1E insulinoma cells

scientific journal article

The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity

scientific article published on 15 February 2018

To β-e or Not to β-e Replicating after 30: Retrospective Dating of Human Pancreatic Islets

scientific article published on October 1, 2010

Transcriptional response of pancreatic beta cells to metabolic stimulation: large scale identification of immediate-early and secondary response genes

scientific article

Transient PAX8 Expression in Islets During Pregnancy Correlates With Beta Cell Survival Revealing a Novel Candidate Gene in Gestational Diabetes Mellitus

article

Using stem cells to produce insulin

scientific article published on 09 July 2015

[Glucose homeostasis ribo-regulated by microRNA]

scientific article published on 01 May 2006

[Pax4, islet plasticity and diabetes]

scientific article published on 01 April 2005