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List of works by Frank Lezoualc'h

5-HT4 receptor and Alzheimer's disease: the amyloid connection

scientific article published on 9 February 2007

A high-affinity monoclonal antibody with functional activity against the 5-hydroxytryptaminergic (5-HT4) receptor

scientific article

Bivalent ligands as specific pharmacological tools for G protein-coupled receptor dimers

scientific article

Catecholamines facilitate VEGF-dependent angiogenesis via β2-adrenoceptor-induced Epac1 and PKA activation

scientific article published on 20 April 2017

Characterization of human 5-HT4(d) receptor desensitization in CHO cells

scientific article

Constitutive dimerization of human serotonin 5-HT4 receptors in living cells

scientific article

Cyclic AMP Sensor EPAC Proteins and Their Role in Cardiovascular Function and Disease

scientific article published on March 2016

Design and synthesis of specific probes for human 5-HT4 receptor dimerization studies

scientific article

Design, synthesis, and biological evaluation of new 5-HT4 receptor agonists: application as amyloid cascade modulators and potential therapeutic utility in Alzheimer's disease

scientific article

Distinct functional effects of human 5-HT4 receptor isoforms on beta-amyloid secretion

scientific article published on 06 March 2008

Epac mediates beta-adrenergic receptor-induced cardiomyocyte hypertrophy

scientific journal article

Epac1 and Epac2 are differentially involved in inflammatory and remodeling processes induced by cigarette smoke

scientific article

Functional characterization of the cAMP-binding proteins Epac in cardiac myocytes

scientific article published on January 2009

Functional effects of PTPN11 (SHP2) mutations causing LEOPARD syndrome on epidermal growth factor-induced phosphoinositide 3-kinase/AKT/glycogen synthase kinase 3beta signaling

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Identification of a tetrahydroquinoline analog as a pharmacological inhibitor of the cAMP-binding protein Epac

scientific article

Immunomodulation by maternal autoantibodies of the fetal serotoninergic 5-HT4 receptor and its consequences in early BALB/c mouse embryonic development

scientific article published on 19 April 2007

Multivalent-based drug design applied to serotonin 5-HT(4) receptor oligomers

scientific article published on January 2009

New insights into serotonin 5-HT4 receptors : a novel therapeutic target for Alzheimer's disease?

scientific article

New insights into the human 5-HT4 receptor binding site: exploration of a hydrophobic pocket

scientific article

PKC-delta and PKC-epsilon: foes of the same family or strangers?

scientific article published on 23 July 2011

Rap-linked cAMP signaling Epac proteins: compartmentation, functioning and disease implications

scientific article published on 22 March 2011

Review of 5-HT4R ligands: state of art and clinical applications

scientific article published on January 2010

Role of Epac in brain and heart

scientific article published on February 2012

Role of the cAMP-binding protein Epac in cardiovascular physiology and pathophysiology

scientific article published on 25 October 2009

SL65.0155, a novel 5-hydroxytryptamine(4) receptor partial agonist with potent cognition-enhancing properties

scientific article

Small GTP-binding proteins and their regulators in cardiac hypertrophy

scientific article published on 13 February 2008

Sustained Epac activation induces calmodulin dependent positive inotropic effect in adult cardiomyocytes

scientific journal article

Synthesis of specific bivalent probes that functionally interact with 5-HT(4) receptor dimers

scientific article

The cAMP binding protein Epac regulates cardiac myofilament function

scholarly article

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