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List of works by Rodolphe Fischmeister

5-HT4 receptor ligands: applications and new prospects

scientific article

A cardiac mitochondrial cAMP signaling pathway regulates calcium accumulation, permeability transition and cell death

scientific article published on 21 April 2016

A comparative analysis of the time course of cardiac Ca2+ current response to rapid applications of beta-adrenergic and dihydropyridine agonists

scientific article published on 01 August 1993

A comparative study of the effects of three guanylyl cyclase inhibitors on the L-type Ca2+ and muscarinic K+ currents in frog cardiac myocytes.

scientific article published on August 1997

A dual effect of cardiac glycosides on Ca current in single cells of frog heart.

scientific article published in March 1986

A loudspeaker-driven system for rapid and multiple solution exchanges in patch-clamp experiments.

scientific article published in April 1992

A new regulation of IL-6 production in adult cardiomyocytes by beta-adrenergic and IL-1 beta receptors and induction of cellular hypertrophy by IL-6 trans-signalling

scientific journal article

A specific pattern of phosphodiesterases controls the cAMP signals generated by different Gs-coupled receptors in adult rat ventricular myocytes.

scientific article

Abnormal sodium current properties contribute to cardiac electrical and contractile dysfunction in a mouse model of myotonic dystrophy type 1.

scientific article published on 10 December 2014

Acetylcholine inhibits Ca2+ current by acting exclusively at a site proximal to adenylyl cyclase in frog cardiac myocytes

scientific article published on 01 March 1996

Acute cardiac effects of neuregulin-1/ErbB signalling.

scientific article

Alteration of vascular reactivity in heart failure: role of phosphodiesterases 3 and 4.

scientific article

Anti-SSA/Ro52 autoantibodies blocking the cardiac 5-HT4 serotoninergic receptor could explain neonatal lupus congenital heart block

scientific article published on 01 October 2000

Antihypertensive and endothelium-dependent vasodilator effects of aqueous extract of Cistus ladaniferus

scientific article published on 26 August 2009

Antihypertensive and vasodilator effects of methanolic extract of Inula viscosa: Biological evaluation and POM analysis of cynarin, chlorogenic acid as potential hypertensive.

scientific article

Arbutus unedo induces endothelium-dependent relaxation of the isolated rat aorta

scientific article published in September 2002

Augmentation of cardiac contractility with no change in L-type Ca2+ current in transgenic mice with a cardiac-directed expression of the human adenylyl cyclase type 8 (AC8).

scientific article

Binding constants determined from Ca2+ current responses to rapid applications and washouts of nifedipine in frog cardiac myocytes.

scientific article published in July 1996

Calcium-mediated inactivation of the calcium conductance in cesium-loaded frog heart cells.

scientific article

Calmodulin kinase II inhibition limits the pro-arrhythmic Ca2+ waves induced by cAMP-phosphodiesterase inhibitors.

scientific article

Carboxy-terminal fragment of fibroblast growth factor 23 induces heart hypertrophy in sickle cell disease

scientific article published on 27 October 2016

Cardiac specific increase in aldosterone production induces coronary dysfunction in aldosterone synthase-transgenic mice.

scientific article

Cardiovascular effects of Urtica dioica L. in isolated rat heart and aorta

scientific article published in September 2002

Changes in external Na induce a membrane current related to the Na-Ca exchange in cesium-loaded frog heart cells.

scientific article

Characterization of human 5-HT4(d) receptor desensitization in CHO cells

scientific article

Characterization of serotonin(4) receptors in adrenocortical aldosterone-producing adenomas: in vivo and in vitro studies

scientific article (publication date: March 2002)

Characterization of the cyclic nucleotide phosphodiesterase subtypes involved in the regulation of the L-type Ca2+ current in rat ventricular myocytes.

scientific article published on May 1999

Compartmentation of cyclic nucleotide signaling in the heart: the role of cyclic nucleotide phosphodiesterases.

scientific article published on October 2006

Constitutive dimerization of human serotonin 5-HT4 receptors in living cells

scientific article

Contribution of BKCa channels to vascular tone regulation by PDE3 and PDE4 is lost in heart failure

scientific article published on 01 January 2019

Control of cytoplasmic and nuclear protein kinase A by phosphodiesterases and phosphatases in cardiac myocytes

scientific article

Crosstalk between Rap1 and Rac regulates secretion of sAPPalpha

scientific article

Cyclic AMP compartmentation due to increased cAMP-phosphodiesterase activity in transgenic mice with a cardiac-directed expression of the human adenylyl cyclase type 8 (AC8).

scientific article

Cyclic AMP phosphodiesterases and Ca2+ current regulation in cardiac cells.

scientific article

Cyclic AMP synthesis and hydrolysis in the normal and failing heart

scientific article published on 24 April 2014

Cyclic Adenosine Monophosphate Phosphodiesterase Type 4 Protects Against Atrial Arrhythmias

scientific article published on 01 June 2012

Cyclic GMP regulation of the L-type Ca(2+) channel current in human atrial myocytes

scientific article published in June 2001

Cyclic guanosine monophosphate compartmentation in rat cardiac myocytes

scientific article published on May 2006

Cyclic nucleotide phosphodiesterases in heart and vessels: A therapeutic perspective.

scientific article published on 13 May 2016

Decreased expression and activity of cAMP phosphodiesterases in cardiac hypertrophy and its impact on beta-adrenergic cAMP signals

scientific article published on 10 September 2009

Decreased sarcolipin protein expression and enhanced sarco(endo)plasmic reticulum Ca2+ uptake in human atrial fibrillation

scientific article

Design and synthesis of specific probes for human 5-HT4 receptor dimerization studies

scientific article

Differential effects of pertussis toxin on the muscarinic regulation of Ca2+ and K+ currents in frog cardiac myocytes.

scientific article

Differential functional effects of two 5-HT4 receptor isoforms in adult cardiomyocytes.

scientific article published on August 2005

Differential regulation of cardiac excitation-contraction coupling by cAMP phosphodiesterase subtypes.

scientific article published on 9 August 2013

Dominant negative Ras attenuates pathological ventricular remodeling in pressure overload cardiac hypertrophy

scientific article

Effect of serotonin4 (5-HT4) receptor agonists on aldosterone secretion in idiopathic hyperaldosteronism

scientific article published on 01 November 2000

Enzymatic assays for probing mitochondrial apoptosis.

scientific article published in January 2015

Feedback control through cGMP-dependent protein kinase contributes to differential regulation and compartmentation of cGMP in rat cardiac myocytes.

scientific article published on 16 September 2010

Functional expression and regulation of the hyperpolarization activated non-selective cation current in embryonic stem cell-derived cardiomyocytes.

scientific article

Functional expression of the hyperpolarization-activated, non-selective cation current I(f) in immortalized HL-1 cardiomyocytes

scientific article

Functional localization of cAMP signalling in cardiac myocytes.

scientific article published on August 2006

Functional studies of the 5'-untranslated region of human 5-HT4 receptor mRNA.

scientific article

G protein-mediated inhibitory effect of a nitric oxide donor on the L-type Ca2+ current in rat ventricular myocytes

scientific article

Glucagon stimulates the cardiac Ca2+ current by activation of adenylyl cyclase and inhibition of phosphodiesterase

scientific article published in Nature

Identification of a tetrahydroquinoline analog as a pharmacological inhibitor of the cAMP-binding protein Epac

scientific article

Identification of optimal reference genes for transcriptomic analyses in normal and diseased human heart

scientific article published on 22 September 2017

Immunomodulation by maternal autoantibodies of the fetal serotoninergic 5-HT4 receptor and its consequences in early BALB/c mouse embryonic development

scientific article published on 19 April 2007

Influence of cell confluence on the cAMP signalling pathway in vascular smooth muscle cells.

scientific article

Interventricular differences in β-adrenergic responses in the canine heart: role of phosphodiesterases.

scientific article

Is cAMP good or bad? Depends on where it's made

scientific article published on 01 March 2006

Isolation of the serotoninergic 5-HT4(e) receptor from human heart and comparative analysis of its pharmacological profile in C6-glial and CHO cell lines

scientific article

Local response of L-type Ca(2+) current to nitric oxide in frog ventricular myocytes

scientific article

Longitudinal distribution of Na+ and Ca2+ channels and beta-adrenoceptors on the sarcolemmal membrane of frog cardiomyocytes

scientific article published on 01 September 1997

Mechanism of action of acetylcholine on calcium current in single cells from frog ventricle

scientific article published on 01 July 1986

Metabolic Inhibition Induces Transient Increase of L-type Ca Current in Human and Rat Cardiac Myocytes ⬇️

scientific article published on 26 March 2019

Metabolic inhibition reduces cardiac L-type Ca2+ channel current due to acidification caused by ATP hydrolysis

scientific article published on 31 August 2017

Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): standardised reporting for model reproducibility, interoperability, and data sharing.

scientific article

Molecular and functional characterization of a 5‐HT4 receptor cloned from human atrium ⬇️

scientific article published on August 4, 1997

Mouse bestrophin-2 is a bona fide Cl(-) channel: identification of a residue important in anion binding and conduction

scientific article

Muscarinic and beta-adrenergic regulation of heart rate, force of contraction and calcium current is preserved in mice lacking endothelial nitric oxide synthase

scientific article published on 01 March 1999

Muscarinic regulation of the L-type calcium current in isolated cardiac myocytes.

scientific article published on January 1997

NO donors potentiate the beta-adrenergic stimulation of I(Ca,L) and the muscarinic activation of I(K,ACh) in rat cardiac myocytes

scientific article

Negative feedback exerted by cAMP-dependent protein kinase and cAMP phosphodiesterase on subsarcolemmal cAMP signals in intact cardiac myocytes: an in vivo study using adenovirus-mediated expression of CNG channels.

scientific article published in October 2004

New VMD2 gene mutations identified in patients affected by Best vitelliform macular dystrophy.

scientific article published on 07 February 2007

New insights into the human 5-HT4 receptor binding site: exploration of a hydrophobic pocket

scientific article

Nitric oxide regulates the calcium current in isolated human atrial myocytes.

scientific article

PDE4 and mAKAPβ are nodal organizers of β2-ARs nuclear PKA signaling in cardiac myocytes.

scientific article

PDEs create local domains of cAMP signaling.

scientific article published on 23 August 2011

Peroxynitrite is a positive inotropic agent in atrial and ventricular fibres of the frog heart

scientific article published on 01 December 1999

Phosphodiesterase 2 Protects Against Catecholamine-Induced Arrhythmia and Preserves Contractile Function After Myocardial Infarction.

scientific article published on 31 October 2016

Phosphodiesterase 2: anti-adrenergic friend or hypertrophic foe in heart disease?

scientific article published on 24 August 2016

Phosphodiesterase 4B in the cardiac L-type Ca²⁺ channel complex regulates Ca²⁺ current and protects against ventricular arrhythmias in mice

scientific journal article

Phosphodiesterase types 3 and 4 regulate the phasic contraction of neonatal rat bladder smooth myocytes via distinct mechanisms

scientific article published on 23 January 2014

Phosphodiesterase-2 is up-regulated in human failing hearts and blunts β-adrenergic responses in cardiomyocytes

scientific article published on 26 June 2013

Phosphoinositide 3-kinase γ protects against catecholamine-induced ventricular arrhythmia through protein kinase A-mediated regulation of distinct phosphodiesterases

scientific journal article

Positive and negative inotropic effects of NO donors in atrial and ventricular fibres of the frog heart

scientific article published on 01 July 1999

Post-translational modifications of cardiac tubulin during chronic heart failure in the rat

scientific article published on 01 August 2002

Post-translational modifications of tubulin and microtubule stability in adult rat ventricular myocytes and immortalized HL-1 cardiomyocytes.

scientific article published on March 2004

Quantitative mRNA analysis of serotonin 5-HT4 receptor isoforms, calcium handling proteins and ion channels in human atrial fibrillation

scientific article published on 28 March 2007

RNA-binding protein CUGBP1 regulates insulin secretion via activation of phosphodiesterase 3B in mice.

scientific article published on 2 June 2016

Rate-limiting steps in the beta-adrenergic stimulation of cardiac calcium current

scientific article

Real-time assessment of myocardial contractility using shear wave imaging

scientific article published on 01 June 2011

Regulation of the amyloid precursor protein ectodomain shedding by the 5-HT4 receptor and Epac.

scientific article published on February 2005

Role of cyclic nucleotide phosphodiesterase isoforms in cAMP compartmentation following beta2-adrenergic stimulation of ICa,L in frog ventricular myocytes

scientific article

Role of the NO-cGMP pathway in the muscarinic regulation of the L-type Ca2+ current in human atrial myocytes.

scientific article published on February 1998

SL65.0155, a novel 5-hydroxytryptamine(4) receptor partial agonist with potent cognition-enhancing properties

scientific article

Sequential changes in autonomic regulation of cardiac myocytes after in vivo endotoxin injection in rat

scientific article published on 01 October 1999

Simultaneous measurements of intracellular cAMP and L-type Ca2+ current in single frog ventricular myocytes

scientific article

Slow inward Ca current in frog heart: theoretical evidence against a voltage-dependent inactivation

scientific article published on 01 September 1982

Spatiotemporal dynamics of beta-adrenergic cAMP signals and L-type Ca2+ channel regulation in adult rat ventricular myocytes: role of phosphodiesterases

scientific article

Species- and tissue-dependent effects of NO and cyclic GMP on cardiac ion channels

scientific article

Sympathetic regulation of cardiac calcium current is due exclusively to cAMP-dependent phosphorylation ⬇️

scientific article published on June 13, 1991

Tannins and catechin gallate mediate the vasorelaxant effect of Arbutus unedo on the rat isolated aorta ⬇️

scientific article published in November 2004

The (R)-enantiomer of CE3F4 is a preferential inhibitor of human exchange protein directly activated by cyclic AMP isoform 1 (Epac1)

scientific article published on 04 October 2013

The 5-HT4 receptor antagonist ML10375 inhibits the constitutive activity of human 5-HT4(c) receptor.

scientific article published on October 1998

The cAMP binding protein Epac modulates Ca2+ sparks by a Ca2+/calmodulin kinase signalling pathway in rat cardiac myocytes

scientific article published on 28 June 2007

The human serotonin 5-HT4 receptor regulates secretion of non-amyloidogenic precursor protein.

scientific article

Two transmembrane Cys residues are involved in 5-HT4 receptor dimerization.

scientific article published on 12 March 2007

Variation of intracellular Ca2+ following Ca2+ current in heart. A theoretical study of ionic diffusion inside a cylindrical cell.

scientific article published on March 1983

Volume sensitivity of the bestrophin family of chloride channels

scientific article published on 25 November 2004

[Role of cyclic nucleotide phosphodiesterases in the cAMP compartmentation in cardiac cells]

scientific article published on 03 April 2012

[Role of cyclic nucleotide phosphodiesterases type 3 and 4 in cardiac excitation-contraction coupling and arrhythmias]

scientific article published on 01 June 2013

beta3-adrenergic receptor activation increases human atrial tissue contractility and stimulates the L-type Ca2+ current

scientific article published on September 2008

cGMP-stimulated cyclic nucleotide phosphodiesterase regulates the basal calcium current in human atrial myocytes

scientific article

β-Adrenergic cAMP signals are predominantly regulated by phosphodiesterase type 4 in cultured adult rat aortic smooth muscle cells

scientific article

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