List of works - Mario A Pagano

2-Dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole: a novel powerful and selective inhibitor of protein kinase CK2.

scientific article published in September 2004

A noncanonical sequence phosphorylated by casein kinase 1 in beta-catenin may play a role in casein kinase 1 targeting of important signaling proteins

scientific article (publication date: 2 September 2003)

Aurora-A site specificity: a study with synthetic peptide substrates

scientific article

Autophosphorylation at the regulatory beta subunit reflects the supramolecular organization of protein kinase CK2.

scientific article

Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA)

scientific article

CFTR mutations altering CFTR fragmentation

scientific article published on January 2013

CK2 regulates in vitro the activity of the yeast cyclin-dependent kinase inhibitor Sic1

scientific article published in 2005

Cooperative Modulation of Protein Kinase CK2 by Separate Domains of Its Regulatory β-Subunit†

scientific article published on 01 October 2000

Cross-talk between PDGF and S1P signalling elucidates the inhibitory effect and potential antifibrotic action of the immunomodulator FTY720 in activated HSC-cultures.

scientific article published on 29 November 2007

Cystic fibrosis transmembrane regulator fragments with the Phe508 deletion exert a dual allosteric control over the master kinase CK2.

scientific article

Detection of phospho-sites generated by protein kinase CK2 in CFTR: mechanistic aspects of Thr1471 phosphorylation

scientific article

Development and exploitation of CK2 inhibitors

scientific article published on June 2005

Fatty Acid-Derived Pro-Toxicants of the Rat Selective Toxicant Norbormide

scientific article published on 4 May 2016

Geldanamycin-induced Lyn dissociation from aberrant Hsp90-stabilized cytosolic complex is an early event in apoptotic mechanisms in B-chronic lymphocytic leukemia

scientific article

Identification of Ellagic Acid as Potent Inhibitor of Protein Kinase CK2: A Successful Example of a Virtual Screening Application

Inhibition of protein kinase CK2 by condensed polyphenolic derivatives. An in vitro and in vivo study

scientific article

Interaction between the SH3 domain of Src family kinases and the proline-rich motif of HTLV-1 p13: a novel mechanism underlying delivery of Src family kinases to mitochondria

scientific article published in November 2011

Label-free fluorescence detection of kinase activity using a gold nanoparticle based indicator displacement assay

scientific article published on 27 November 2014

Linear motifs in the C-terminus of D. melanogaster cryptochrome

scientific article published on 9 February 2007

Lyn sustains oncogenic signaling in chronic lymphocytic leukemia by strengthening SET-mediated inhibition of PP2A.

scientific article published on 30 April 2015

Lyn-mediated SHP-1 recruitment to CD5 contributes to resistance to apoptosis of B-cell chronic lymphocytic leukemia cells.

scientific article

Lyn-mediated mitochondrial tyrosine phosphorylation is required to preserve mitochondrial integrity in early liver regeneration

scientific article published on 23 December 2009

Lyn-mediated procaspase 8 dimerization blocks apoptotic signaling in B-cell chronic lymphocytic leukemia

scientific article published on 18 December 2013

MBNL142 and MBNL143 gene isoforms, overexpressed in DM1-patient muscle, encode for nuclear proteins interacting with Src family kinases

scientific article published on 15 August 2013

Mass Spectrometry Analysis of a Protein Kinase CK2β Subunit Interactome Isolated from Mouse Brain by Affinity Chromatography

article

Modulation of protein kinase CK2 activity by fragments of CFTR encompassing F508 may reflect functional links with cystic fibrosis pathogenesis

scientific article published on 3 July 2008

Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole

scientific article published in December 2004

Pancreatic and duodenal homeobox 1 (PDX1) phosphorylation at serine-269 is HIPK2-dependent and affects PDX1 subnuclear localization

scientific article

Phosphorylation of calmodulin fragments by protein kinase CK2. Mechanistic aspects and structural consequences.

scientific article

Polyhalogenobenzimidazoles: synthesis and their inhibitory activity against casein kinases

scientific journal article

Protein kinase CK2: a newcomer in the 'druggable kinome'.

scientific article published in December 2006

Pyrazoloquinazoline Tricyclic System as Novel Scaffold to Design New Kinase CK2 Inhibitors

Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2

scientific article

Semi-synthetic derivatives of natural isoflavones from Maclura pomifera as a novel class of PDE-5A inhibitors.

scientific article

Structural features underlying the selectivity of the kinase inhibitors NBC and dNBC: role of a nitro group that discriminates between CK2 and DYRK1A

scientific article

Tetrabromocinnamic Acid (TBCA) and Related Compounds Represent a New Class of Specific Protein Kinase CK2 Inhibitors

scholarly article by Mario A Pagano published in January 2007

The Regulatory β Subunit of Protein Kinase CK2 Contributes to the Recognition of the Substrate Consensus Sequence. A Study with an eIF2β-Derived Peptide†

scientific article published in 2008

The pleiotropic protein kinase CK2 phosphorylates HTLV-1 Tax protein in vitro, targeting its PDZ-binding motif

scientific article published on 5 June 2010

The selectivity of inhibitors of protein kinase CK2: an update

scientific article

The tyrosine phosphatase SHP-1 inhibits proliferation of activated hepatic stellate cells by impairing PDGF receptor signaling.

scientific article published on 18 October 2013

Thiol redox systems and protein kinases in hepatic stellate cell regulatory processes

scientific article published on April 2010

Tyrosine phosphorylation and liver regeneration: A glance at intracellular transducers.

scientific article published on 20 December 2011

TyrosineVersusSerine/Threonine Phosphorylation by Protein Kinase Casein Kinase-2

scientific article published in Journal of Biological Chemistry

Understanding protein kinase CK2 mis-regulation upon F508del CFTR expression

scientific article

Unique features of HIV-1 Rev protein phosphorylation by protein kinase CK2 (‘casein kinase-2’)

article

pCMB Treatment Reveals the Essential Role of Cysteinyl Residues in Conferring Functional Competence to the Regulatory Subunit of Protein Kinase CK2

scientific article published on 01 January 2000

List of works by Mario A Pagano

2-Dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole: a novel powerful and selective inhibitor of protein kinase CK2.

A noncanonical sequence phosphorylated by casein kinase 1 in beta-catenin may play a role in casein kinase 1 targeting of important signaling proteins

Aurora-A site specificity: a study with synthetic peptide substrates

Autophosphorylation at the regulatory beta subunit reflects the supramolecular organization of protein kinase CK2.

Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA)

CFTR mutations altering CFTR fragmentation

CK2 regulates in vitro the activity of the yeast cyclin-dependent kinase inhibitor Sic1

Cooperative Modulation of Protein Kinase CK2 by Separate Domains of Its Regulatory β-Subunit†

Cross-talk between PDGF and S1P signalling elucidates the inhibitory effect and potential antifibrotic action of the immunomodulator FTY720 in activated HSC-cultures.

Cystic fibrosis transmembrane regulator fragments with the Phe508 deletion exert a dual allosteric control over the master kinase CK2.

Detection of phospho-sites generated by protein kinase CK2 in CFTR: mechanistic aspects of Thr1471 phosphorylation

Development and exploitation of CK2 inhibitors

Fatty Acid-Derived Pro-Toxicants of the Rat Selective Toxicant Norbormide

Geldanamycin-induced Lyn dissociation from aberrant Hsp90-stabilized cytosolic complex is an early event in apoptotic mechanisms in B-chronic lymphocytic leukemia

Identification of Ellagic Acid as Potent Inhibitor of Protein Kinase CK2: A Successful Example of a Virtual Screening Application

Inhibition of protein kinase CK2 by condensed polyphenolic derivatives. An in vitro and in vivo study

Interaction between the SH3 domain of Src family kinases and the proline-rich motif of HTLV-1 p13: a novel mechanism underlying delivery of Src family kinases to mitochondria

Label-free fluorescence detection of kinase activity using a gold nanoparticle based indicator displacement assay

Linear motifs in the C-terminus of D. melanogaster cryptochrome

Lyn sustains oncogenic signaling in chronic lymphocytic leukemia by strengthening SET-mediated inhibition of PP2A.

Lyn-mediated SHP-1 recruitment to CD5 contributes to resistance to apoptosis of B-cell chronic lymphocytic leukemia cells.

Lyn-mediated mitochondrial tyrosine phosphorylation is required to preserve mitochondrial integrity in early liver regeneration

Lyn-mediated procaspase 8 dimerization blocks apoptotic signaling in B-cell chronic lymphocytic leukemia

MBNL142 and MBNL143 gene isoforms, overexpressed in DM1-patient muscle, encode for nuclear proteins interacting with Src family kinases

Mass Spectrometry Analysis of a Protein Kinase CK2β Subunit Interactome Isolated from Mouse Brain by Affinity Chromatography

Modulation of protein kinase CK2 activity by fragments of CFTR encompassing F508 may reflect functional links with cystic fibrosis pathogenesis

Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole

Pancreatic and duodenal homeobox 1 (PDX1) phosphorylation at serine-269 is HIPK2-dependent and affects PDX1 subnuclear localization

Phosphorylation of calmodulin fragments by protein kinase CK2. Mechanistic aspects and structural consequences.

Polyhalogenobenzimidazoles: synthesis and their inhibitory activity against casein kinases

Protein kinase CK2: a newcomer in the 'druggable kinome'.

Pyrazoloquinazoline Tricyclic System as Novel Scaffold to Design New Kinase CK2 Inhibitors

Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2

Semi-synthetic derivatives of natural isoflavones from Maclura pomifera as a novel class of PDE-5A inhibitors.

Structural features underlying the selectivity of the kinase inhibitors NBC and dNBC: role of a nitro group that discriminates between CK2 and DYRK1A

Tetrabromocinnamic Acid (TBCA) and Related Compounds Represent a New Class of Specific Protein Kinase CK2 Inhibitors

The Regulatory β Subunit of Protein Kinase CK2 Contributes to the Recognition of the Substrate Consensus Sequence. A Study with an eIF2β-Derived Peptide†

The pleiotropic protein kinase CK2 phosphorylates HTLV-1 Tax protein in vitro, targeting its PDZ-binding motif

The selectivity of inhibitors of protein kinase CK2: an update

The tyrosine phosphatase SHP-1 inhibits proliferation of activated hepatic stellate cells by impairing PDGF receptor signaling.

Thiol redox systems and protein kinases in hepatic stellate cell regulatory processes

Tyrosine phosphorylation and liver regeneration: A glance at intracellular transducers.

TyrosineVersusSerine/Threonine Phosphorylation by Protein Kinase Casein Kinase-2

Understanding protein kinase CK2 mis-regulation upon F508del CFTR expression

Unique features of HIV-1 Rev protein phosphorylation by protein kinase CK2 (‘casein kinase-2’)

pCMB Treatment Reveals the Essential Role of Cysteinyl Residues in Conferring Functional Competence to the Regulatory Subunit of Protein Kinase CK2