List of works - Pasquale Mosesso

A comparative study of the anticlastogenic effects of chlorophyllin on N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) or 7,12-dimethylbenz (α) anthracene (DMBA) induced micronuclei in mammalian cells in vitro and in vivo.

scientific article published on 15 September 2012

A selective de-O-methylation of guaiacyl lignans to corresponding catechol derivatives by 2-iodoxybenzoic acid (IBX). The role of the catechol moiety on the toxicity of lignans.

scientific article

Approach followed for the refined exposure assessment as part of the safety assessment of food additives under re‐evaluation

scientific article published in October 2017

Caffeine effect on the mitotic delay induced by G2 treatment with UVC or mitomycin C.

scientific article published on September 1998

Catalytic inhibition of topoisomerase II in Werner's syndrome cell lines enhances chromosomal damage induced by X-rays in the G2 phase of the cell cycle

scientific article published on July 2000

Chromosome radiosensitivity in human G2 lymphocytes and cell-cycle progression

scientific article published on 01 May 1999

Clarification of some aspects related to genotoxicity assessment

scientific article published in December 2017

Clastogenic effects of the dithiocarbamate fungicides thiram and ziram in Chinese hamster cell lines cultured in vitro

scientific article published on January 1994

Cytogenetic analyses of Azadirachtin reveal absence of genotoxicity but marked antiproliferative effects in human lymphocytes and CHO cells in vitro.

scientific article

Cytogenetic evaluation of extractable agents from airborne particulate matter generated in the city of Catania (Italy).

scientific article published in July 2004

Cytogenetic evidence that DNA topoisomerase II is not involved in radiation induced chromsome-type aberrations.

scientific article published on 15 June 2015

Distribution of camptothecin-induced break points in Chinese hamster cells treated in late S and G2 phases of the cell cycle

scientific article published on May 1998

Effect of blueberries (BB) on micronuclei induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and 7,12-dimethylbenz(a)anthracene (DMBA) in mammalian cells, assessed in in vitro and in vivo assays.

scientific article published on 20 September 2013

Enhancement of genetic instability in human B cells by Epstein-Barr virus latent infection

scientific article published on May 2001

Evaluation of bleomycin-induced chromosome aberrations under simulated microgravity conditions in human lymphocytes using "FISH" techniques.

scientific article published on January 1998

Evaluation of cytogenetic effects of a naturally occurring non-ice-nucleation Pseudomonas fluorescens strain in Chinese hamster ovary (CHO) cells

scientific article published on 01 January 1995

Evidence that camptothecin-induced aberrations in the G2 phase of cell cycle of Chinese hamster ovary (CHO) cell lines is associated with transcription

article

Furan carcinogenicity: DNA binding and genotoxicity of furan in rats in vivo.

scientific article published on 03 August 2012

Genotoxicity assessment of chemical mixtures

scientific article published on 18 December 2018

Genotoxicity studies on sertaconazole

scientific article

HUman MicroNucleus project: international database comparison for results with the cytokinesis-block micronucleus assay in human lymphocytes: I. Effect of laboratory protocol, scoring criteria, and host factors on the frequency of micronuclei

scientific article

High-dose-level effects in mutagenicity assays utilizing mammalian cells in culture.

scientific article

In vitro cytogenetic assays: chromosomal aberrations and micronucleus tests.

scientific article published in January 2013

In vitro cytogenetic results supporting a DNA nonreactive mechanism for ochratoxin A, potentially relevant for its carcinogenicity.

scientific article published on 23 May 2008

Induction of chromosomal aberrations (unstable and stable) by inhibitors of topoisomerase II, m-AMSA and VP16, using conventional Giemsa staining and chromosome painting techniques.

scientific article

Lack of effect of caffeine post-treatment on X-ray-induced chromosomal aberrations in Werner's syndrome lymphoblastoid cell lines: a preliminary report

scientific article

Lonidamine: a non-mutagenic antitumor agent

scientific article published on September 1990

Low molecular weight polyethylene glycol induces chromosome aberrations in Chinese hamster cells cultured in vitro

scientific article

Methyltrioxorhenium catalysed synthesis of highly oxidised aryltetralin lignans with anti-topoisomerase II and apoptogenic activities

scientific article published on November 2005

Ochratoxin a causes DNA damage and cytogenetic effects but no DNA adducts in rats.

scientific article published in August 2005

Perturbation of mitosis through inhibition of histone acetyltransferases: the key to ochratoxin a toxicity and carcinogenicity?

scientific article

Potassium bromate but not X-rays cause unexpectedly elevated levels of DNA breakage similar to those induced by ultraviolet light in Cockayne syndrome (CS-B) fibroblasts

scientific article

Re-evaluation of calcium silicate (E 552), magnesium silicate (E 553a(i)), magnesium trisilicate (E 553a(ii)) and talc (E 553b) as food additives

scientific article published on 02 August 2018

Re-evaluation of carrageenan (E 407) and processed Eucheuma seaweed (E 407a) as food additives

scientific article published on 26 April 2018

Re-evaluation of gellan gum (E 418) as food additive

scientific article published on 20 June 2018

Re-evaluation of polyglycerol esters of fatty acids (E 475) as a food additive

scientific article published on 20 December 2017

Re-evaluation of propane-1,2-diol (E 1520) as a food additive

scientific article published on 05 April 2018

Re-evaluation of propane-1,2-diol alginate (E 405) as a food additive

scientific article published on 27 July 2018

Re-evaluation of silicon dioxide (E 551) as a food additive

scientific article published on 17 January 2018

Re-evaluation of sodium nitrate (E 251) and potassium nitrate (E 252) as food additives

scientific article

Re-evaluation of sodium, potassium and calcium salts of fatty acids (E 470a) and magnesium salts of fatty acids (E 470b) as food additives

scientific article published on 02 March 2018

Relationship between chromatin structure, DNA damage and repair following X-irradiation of human lymphocytes

scientific article published on 16 March 2010

Report from working group on in vitro tests for chromosomal aberrations

scientific article

Re‐evaluation of acacia gum (E 414) as a food additive

scientific article published in April 2017

Re‐evaluation of alginic acid and its sodium, potassium, ammonium and calcium salts (E 400–E 404) as food additives

scientific article published in November 2017

Re‐evaluation of fatty acids (E 570) as a food additive

scientific article published in May 2017

Re‐evaluation of glutamic acid (E 620), sodium glutamate (E 621), potassium glutamate (E 622), calcium glutamate (E 623), ammonium glutamate (E 624) and magnesium glutamate (E 625) as food additives

scientific article published in July 2017

Re‐evaluation of glycerol (E 422) as a food additive

scientific article published in March 2017

Re‐evaluation of guar gum (E 412) as a food additive

scientific article published in February 2017

Re‐evaluation of konjac gum (E 425 i) and konjac glucomannan (E 425 ii) as food additives

scientific article published in June 2017

Re‐evaluation of lecithins (E 322) as a food additive

scientific article published in April 2017

Re‐evaluation of locust bean gum (E 410) as a food additive

scientific article published in January 2017

Re‐evaluation of mono‐ and di‐glycerides of fatty acids (E 471) as food additives

scientific article published in November 2017

Re‐evaluation of oxidised starch (E 1404), monostarch phosphate (E 1410), distarch phosphate (E 1412), phosphated distarch phosphate (E 1413), acetylated distarch phosphate (E 1414), acetylated starch (E 1420), acetylated distarch adipate (E 1422)...

scientific article published in October 2017

Re‐evaluation of pectin (E 440i) and amidated pectin (E 440ii) as food additives

scientific article published in July 2017

Re‐evaluation of polyglycerol polyricinoleate (E 476) as a food additive

scientific article published in March 2017

Re‐evaluation of potassium nitrite (E 249) and sodium nitrite (E 250) as food additives

scientific article published in June 2017

Re‐evaluation of sorbitan monostearate (E 491), sorbitan tristearate (E 492), sorbitan monolaurate (E 493), sorbitan monooleate (E 494) and sorbitan monopalmitate (E 495) when used as food additives

scientific article published in May 2017

Re‐evaluation of soybean hemicellulose (E 426) as a food additive

scientific article published in March 2017

Re‐evaluation of tara gum (E 417) as a food additive

scientific article published in June 2017

Re‐evaluation of tragacanth (E 413) as a food additive

scientific article published in June 2017

Re‐evaluation of xanthan gum (E 415) as a food additive ⬇️

scientific article published in July 2017

Safety of benzophenone to be used as flavouring

scientific article published in November 2017

Safety of ethyl acrylate to be used as flavouring

scientific article published in November 2017

Safety of hydroxyanthracene derivatives for use in food

scientific article published on 23 January 2018

Safety of the proposed amendment of the specifications for the food additive polyvinyl alcohol‐polyethylene glycol‐graft‐co‐polymer (E 1209)

scientific article published in June 2017

Scientific Opinion of Flavouring Group Evaluation 406 (FGE.406): (S)-1-(3-(((4-amino-2,2-dioxido-1H-benzo[c][1,2,6]thiadiazin-5-yl)oxy)methyl)piperidin-1-yl)-3-methylbutan-1-one

scientific article published on 23 February 2018

Scientific Opinion of Flavouring Group Evaluation 410 (FGE.410): 4’,5,7‐trihydroxyflavanone from chemical group 25 (phenol derivatives containing ring‐alkyl, ring‐alkoxy, and side‐chains with an oxygenated functional group)

scientific article published in November 2017

Scientific Opinion of Flavouring Group Evaluation 411 (FGE.411): 2-(4-methylphenoxy)-N-(1H-pyrazol-3-yl)-N-(thiophen-2-ylmethyl)acetamide from chemical group 30 (miscellaneous substances)

scientific article published on 19 October 2018

Scientific Opinion on Flavouring Group Evaluation 200, Revision 1 (FGE.200 Rev.1): 74 α,β-unsaturated aliphatic aldehydes and precursors from chemical subgroup 1.1.1 of FGE.19

scientific article published on 19 October 2018

Scientific Opinion on Flavouring Group Evaluation 201 Revision 2 (FGE.201Rev2): 2-alkylated, aliphatic, acyclic alpha,beta-unsaturated aldehydes and precursors, with or without additional double-bonds, from chemical subgroup 1.1.2 of FGE.19

scientific article published on 17 October 2018

Scientific Opinion on Flavouring Group Evaluation 203, Revision 2 (FGE.203Rev2): α,β-unsaturated aliphatic aldehydes and precursors from chemical subgroup 1.1.4 of FGE.19 with two or more conjugated double-bonds and with or without additional non-co

scientific article published on 20 July 2018

Scientific Opinion on Flavouring Group Evaluation 208 Revision 2 (FGE.208Rev2): Consideration of genotoxicity data on alicyclic aldehydes with α,β‐unsaturation in ring/side‐chain and precursors from chemical subgroup 2.2 of FGE.19

scientific article published in May 2017

Scientific Opinion on Flavouring Group Evaluation 226 Revision 1 (FGE.226Rev1): consideration of genotoxicity data on one α,β‐unsaturated aldehyde from chemical subgroup 1.1.1(b) of FGE.19

scientific article published in May 2017

Scientific Opinion on Flavouring Group Evaluation 49, Revision 1 (FGE.49Rev1): xanthine alkaloids from the priority list

scientific article published in April 2017

Scientific Opinion on Flavouring Group Evaluation 63, Revision 3 (FGE.63Rev3): aliphatic secondary alcohols, ketones and related esters evaluated by JECFA (59th and 69th meetings) structurally related to saturated and unsaturated aliphatic seconda...

scientific article published in January 2017

Scientific Opinion on Flavouring Group Evaluation 7, Revision 5 (FGE.07Rev5): saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched‐chain carboxylic acids from chemical gr...

scientific article published in March 2017

Scientific opinion of Flavouring Group Evaluation 502 (FGE.502): grill flavour ‘Grillin’ 5078’

scientific article published in September 2017

Scientific opinion of Flavouring Group Evaluation 503 (FGE.503): grill flavour ‘Grillin’ CB‐200SF’

scientific article published in September 2017

Scientific opinion on flavouring group evaluation 77, revision 3 (FGE.77Rev3): consideration of pyridine, pyrrole and quinoline derivatives evaluated by JECFA (63rd meeting) structurally related to pyridine, pyrrole, indole and quinoline derivatives

scientific article published on 25 April 2018

Scientific opinion on the safety of green tea catechins

scientific article published on 18 April 2018

Scientific opinion on the safety of monacolins in red yeast rice

scientific article published on 03 August 2018

Statement on the validity of the conclusions of a mouse carcinogenicity study on sucralose (E 955) performed by the Ramazzini Institute

scientific article published in May 2017

Terrestrial gastropods (Helix spp) as sentinels of primary DNA damage for biomonitoring purposes: a validation study.

scientific article published on 26 February 2013

The genetic toxicology of 6-mercaptopurine

scientific article

The induction of forward gene mutation and gene conversion in yeasts by treatment with cyclophosphamide in vitro and in vivo

scientific article published on 01 November 1983

The involvement of chromatin condensation in camptothecin-induced chromosome breaks in G0 human lymphocytes

scientific article published on 01 January 1999

The novel human gene aprataxin is directly involved in DNA single-strand-break repair.

scientific article

The protective effect of L-carnitine in peripheral blood human lymphocytes exposed to oxidative agents

scientific article published on 23 November 2005

The use of cyprinodont fish, Aphanius fasciatus, as a sentinel organism to detect complex genotoxic mixtures in the coastal lagoon ecosystem.

scientific article published on 24 December 2011

Ultrasound driven assembly of lignin into microcapsules for storage and delivery of hydrophobic molecules

scientific article

Utility of B-13 progenitor-derived hepatocytes in hepatotoxicity and genotoxicity studies

scientific article

Werner's syndrome cell lines are hypersensitive to camptothecin-induced chromosomal damage

scientific article

Werner's syndrome lymphoblastoid cells are hypersensitive to topoisomerase II inhibitors in the G2 phase of the cell cycle

scientific article

X-ray-induced chromosome aberrations in human lymphocytes in vitro are potentiated under simulated microgravity conditions (Clinostat).

scientific article published in January 2001

List of works by Pasquale Mosesso

A comparative study of the anticlastogenic effects of chlorophyllin on N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) or 7,12-dimethylbenz (α) anthracene (DMBA) induced micronuclei in mammalian cells in vitro and in vivo.

A selective de-O-methylation of guaiacyl lignans to corresponding catechol derivatives by 2-iodoxybenzoic acid (IBX). The role of the catechol moiety on the toxicity of lignans.

Approach followed for the refined exposure assessment as part of the safety assessment of food additives under re‐evaluation

Caffeine effect on the mitotic delay induced by G2 treatment with UVC or mitomycin C.

Catalytic inhibition of topoisomerase II in Werner's syndrome cell lines enhances chromosomal damage induced by X-rays in the G2 phase of the cell cycle

Chromosome radiosensitivity in human G2 lymphocytes and cell-cycle progression

Clarification of some aspects related to genotoxicity assessment

Clastogenic effects of the dithiocarbamate fungicides thiram and ziram in Chinese hamster cell lines cultured in vitro

Cytogenetic analyses of Azadirachtin reveal absence of genotoxicity but marked antiproliferative effects in human lymphocytes and CHO cells in vitro.

Cytogenetic evaluation of extractable agents from airborne particulate matter generated in the city of Catania (Italy).

Cytogenetic evidence that DNA topoisomerase II is not involved in radiation induced chromsome-type aberrations.

Distribution of camptothecin-induced break points in Chinese hamster cells treated in late S and G2 phases of the cell cycle

Effect of blueberries (BB) on micronuclei induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and 7,12-dimethylbenz(a)anthracene (DMBA) in mammalian cells, assessed in in vitro and in vivo assays.

Enhancement of genetic instability in human B cells by Epstein-Barr virus latent infection

Evaluation of bleomycin-induced chromosome aberrations under simulated microgravity conditions in human lymphocytes using "FISH" techniques.

Evaluation of cytogenetic effects of a naturally occurring non-ice-nucleation Pseudomonas fluorescens strain in Chinese hamster ovary (CHO) cells

Evidence that camptothecin-induced aberrations in the G2 phase of cell cycle of Chinese hamster ovary (CHO) cell lines is associated with transcription

Furan carcinogenicity: DNA binding and genotoxicity of furan in rats in vivo.

Genotoxicity assessment of chemical mixtures

Genotoxicity studies on sertaconazole

HUman MicroNucleus project: international database comparison for results with the cytokinesis-block micronucleus assay in human lymphocytes: I. Effect of laboratory protocol, scoring criteria, and host factors on the frequency of micronuclei

High-dose-level effects in mutagenicity assays utilizing mammalian cells in culture.

In vitro cytogenetic assays: chromosomal aberrations and micronucleus tests.

In vitro cytogenetic results supporting a DNA nonreactive mechanism for ochratoxin A, potentially relevant for its carcinogenicity.

Induction of chromosomal aberrations (unstable and stable) by inhibitors of topoisomerase II, m-AMSA and VP16, using conventional Giemsa staining and chromosome painting techniques.

Lack of effect of caffeine post-treatment on X-ray-induced chromosomal aberrations in Werner's syndrome lymphoblastoid cell lines: a preliminary report

Lonidamine: a non-mutagenic antitumor agent

Low molecular weight polyethylene glycol induces chromosome aberrations in Chinese hamster cells cultured in vitro

Methyltrioxorhenium catalysed synthesis of highly oxidised aryltetralin lignans with anti-topoisomerase II and apoptogenic activities

Ochratoxin a causes DNA damage and cytogenetic effects but no DNA adducts in rats.

Perturbation of mitosis through inhibition of histone acetyltransferases: the key to ochratoxin a toxicity and carcinogenicity?

Potassium bromate but not X-rays cause unexpectedly elevated levels of DNA breakage similar to those induced by ultraviolet light in Cockayne syndrome (CS-B) fibroblasts

Re-evaluation of calcium silicate (E 552), magnesium silicate (E 553a(i)), magnesium trisilicate (E 553a(ii)) and talc (E 553b) as food additives

Re-evaluation of carrageenan (E 407) and processed Eucheuma seaweed (E 407a) as food additives

Re-evaluation of gellan gum (E 418) as food additive

Re-evaluation of polyglycerol esters of fatty acids (E 475) as a food additive

Re-evaluation of propane-1,2-diol (E 1520) as a food additive

Re-evaluation of propane-1,2-diol alginate (E 405) as a food additive

Re-evaluation of silicon dioxide (E 551) as a food additive

Re-evaluation of sodium nitrate (E 251) and potassium nitrate (E 252) as food additives

Re-evaluation of sodium, potassium and calcium salts of fatty acids (E 470a) and magnesium salts of fatty acids (E 470b) as food additives

Relationship between chromatin structure, DNA damage and repair following X-irradiation of human lymphocytes

Report from working group on in vitro tests for chromosomal aberrations

Re‐evaluation of acacia gum (E 414) as a food additive

Re‐evaluation of alginic acid and its sodium, potassium, ammonium and calcium salts (E 400–E 404) as food additives

Re‐evaluation of fatty acids (E 570) as a food additive

Re‐evaluation of glutamic acid (E 620), sodium glutamate (E 621), potassium glutamate (E 622), calcium glutamate (E 623), ammonium glutamate (E 624) and magnesium glutamate (E 625) as food additives

Re‐evaluation of glycerol (E 422) as a food additive

Re‐evaluation of guar gum (E 412) as a food additive

Re‐evaluation of konjac gum (E 425 i) and konjac glucomannan (E 425 ii) as food additives

Re‐evaluation of lecithins (E 322) as a food additive

Re‐evaluation of locust bean gum (E 410) as a food additive

Re‐evaluation of mono‐ and di‐glycerides of fatty acids (E 471) as food additives

Re‐evaluation of oxidised starch (E 1404), monostarch phosphate (E 1410), distarch phosphate (E 1412), phosphated distarch phosphate (E 1413), acetylated distarch phosphate (E 1414), acetylated starch (E 1420), acetylated distarch adipate (E 1422)...

Re‐evaluation of pectin (E 440i) and amidated pectin (E 440ii) as food additives

Re‐evaluation of polyglycerol polyricinoleate (E 476) as a food additive

Re‐evaluation of potassium nitrite (E 249) and sodium nitrite (E 250) as food additives

Re‐evaluation of sorbitan monostearate (E 491), sorbitan tristearate (E 492), sorbitan monolaurate (E 493), sorbitan monooleate (E 494) and sorbitan monopalmitate (E 495) when used as food additives

Re‐evaluation of soybean hemicellulose (E 426) as a food additive

Re‐evaluation of tara gum (E 417) as a food additive

Re‐evaluation of tragacanth (E 413) as a food additive

Re‐evaluation of xanthan gum (E 415) as a food additive ⬇️

Safety of benzophenone to be used as flavouring

Safety of ethyl acrylate to be used as flavouring

Safety of hydroxyanthracene derivatives for use in food

Safety of the proposed amendment of the specifications for the food additive polyvinyl alcohol‐polyethylene glycol‐graft‐co‐polymer (E 1209)

Scientific Opinion of Flavouring Group Evaluation 406 (FGE.406): (S)-1-(3-(((4-amino-2,2-dioxido-1H-benzo[c][1,2,6]thiadiazin-5-yl)oxy)methyl)piperidin-1-yl)-3-methylbutan-1-one

Scientific Opinion of Flavouring Group Evaluation 410 (FGE.410): 4’,5,7‐trihydroxyflavanone from chemical group 25 (phenol derivatives containing ring‐alkyl, ring‐alkoxy, and side‐chains with an oxygenated functional group)

Scientific Opinion of Flavouring Group Evaluation 411 (FGE.411): 2-(4-methylphenoxy)-N-(1H-pyrazol-3-yl)-N-(thiophen-2-ylmethyl)acetamide from chemical group 30 (miscellaneous substances)

Scientific Opinion on Flavouring Group Evaluation 200, Revision 1 (FGE.200 Rev.1): 74 α,β-unsaturated aliphatic aldehydes and precursors from chemical subgroup 1.1.1 of FGE.19

Scientific Opinion on Flavouring Group Evaluation 201 Revision 2 (FGE.201Rev2): 2-alkylated, aliphatic, acyclic alpha,beta-unsaturated aldehydes and precursors, with or without additional double-bonds, from chemical subgroup 1.1.2 of FGE.19

Scientific Opinion on Flavouring Group Evaluation 203, Revision 2 (FGE.203Rev2): α,β-unsaturated aliphatic aldehydes and precursors from chemical subgroup 1.1.4 of FGE.19 with two or more conjugated double-bonds and with or without additional non-co

Scientific Opinion on Flavouring Group Evaluation 208 Revision 2 (FGE.208Rev2): Consideration of genotoxicity data on alicyclic aldehydes with α,β‐unsaturation in ring/side‐chain and precursors from chemical subgroup 2.2 of FGE.19

Scientific Opinion on Flavouring Group Evaluation 226 Revision 1 (FGE.226Rev1): consideration of genotoxicity data on one α,β‐unsaturated aldehyde from chemical subgroup 1.1.1(b) of FGE.19

Scientific Opinion on Flavouring Group Evaluation 49, Revision 1 (FGE.49Rev1): xanthine alkaloids from the priority list

Scientific Opinion on Flavouring Group Evaluation 63, Revision 3 (FGE.63Rev3): aliphatic secondary alcohols, ketones and related esters evaluated by JECFA (59th and 69th meetings) structurally related to saturated and unsaturated aliphatic seconda...

Scientific Opinion on Flavouring Group Evaluation 7, Revision 5 (FGE.07Rev5): saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched‐chain carboxylic acids from chemical gr...

Scientific opinion of Flavouring Group Evaluation 502 (FGE.502): grill flavour ‘Grillin’ 5078’

Scientific opinion of Flavouring Group Evaluation 503 (FGE.503): grill flavour ‘Grillin’ CB‐200SF’