Search filters

List of works by Christel Herold-Mende

A fusogenic dengue virus-derived peptide enhances antitumor efficacy of an antibody-ribonuclease fusion protein targeting the EGF receptor

scientific article published on October 2014

ABCC drug efflux pumps and organic anion uptake transporters in human gliomas and the blood-tumor barrier

scientific article

AKT1E17K mutations cluster with meningothelial and transitional meningiomas and can be detected by SFRP1 immunohistochemistry

scientific article published on 6 October 2013

AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion

scientific article published on 11 December 2020

ATIM-35. VXM01 PHASE I STUDY IN PATIENTS WITH PROGRESSIVE GLIOBLASTOMA – FINAL RESULTS

ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma

scientific article published on 27 November 2014

Aberrant expression of retinoic acid signaling molecules influences patient survival in astrocytic gliomas

scientific article

Aberrant self-renewal and quiescence contribute to the aggressiveness of glioblastoma

scientific article published on 10 July 2014

Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities

scientific article published on 19 June 2015

An EGF receptor targeting Ranpirnase-diabody fusion protein mediates potent antitumour activity in vitro and in vivo

scientific article

Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma

scientific article published on 29 January 2011

Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations

scientific article published on 21 March 2018

Angiogenic growth factors in tissue homogenates of HNSCC: expression pattern, prognostic relevance, and interrelationships

scientific article published on 31 March 2009

Antigenic expression and spontaneous immune responses support the use of a selected peptide set from the IMA950 glioblastoma vaccine for immunotherapy of grade II and III glioma

scientific article published on 7 November 2017

Antiglioma activity of 2,2':6',2"-terpyridineplatinum(II) complexes in a rat model--effects on cellular redox metabolism

scientific article published on 19 October 2005

Antimalarial versus cytotoxic properties of dual drugs derived from 4-aminoquinolines and Mannich bases: interaction with DNA.

scientific article published on April 2010

Antiproliferative efficacies but minor drug transporter inducing effects of paclitaxel, cisplatin, or 5-fluorouracil in a murine xenograft model for head and neck squamous cell carcinoma

scientific article published on 21 January 2014

Antitumor immunization of head and neck squamous cell carcinoma patients with a virus-modified autologous tumor cell vaccine

scientific article published in January 2005

Antitumor vaccination in patients with head and neck squamous cell carcinomas with autologous virus-modified tumor cells

scientific article published in November 2004

Antitumor vaccination of patients with glioblastoma multiforme: a pilot study to assess feasibility, safety, and clinical benefit

scientific article published on 27 September 2004

Association of Stem Cell-Related Markers and Survival in Astrocytic Gliomas ⬇️

scientific article published on March 1, 2011

Association of drug transporter expression with mortality and progression-free survival in stage IV head and neck squamous cell carcinoma

scientific article

Asymmetric Centriole Numbers at Spindle Poles Cause Chromosome Missegregation in Cancer

scientific article published in August 2017

Autocrine pathways of the vascular endothelial growth factor (VEGF) in glioblastoma multiforme: clinical relevance of radiation-induced increase of VEGF levels

scientific article published in January 2004

BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1.

scientific article published on 23 June 2013

BRAF V600E analysis for the differentiation of papillary craniopharyngiomas and Rathke's cleft cysts.

scientific article published on 2 May 2015

BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas

scientific article published on May 2008

Basal caspase activity promotes migration and invasiveness in glioblastoma cells

scientific article published on December 2007

Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells

scientific article

CD133/prominin1 is prognostic for GBM patient's survival, but inversely correlated with cysteine cathepsins' expression in glioblastoma derived spheroids ⬇️

scientific article published on June 3, 2011

CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas

scientific article published on 17 May 2012

Carbon irradiation overcomes glioma radioresistance by eradicating stem cells and forming an antiangiogenic and immunopermissive niche

Cellular pharmacokinetic/pharmacodynamic relationship of platinum cytostatics in head and neck squamous cell carcinoma evaluated by liquid chromatography coupled to tandem mass spectrometry

scientific article

Chemotherapy with BCNU in recurrent glioma: Analysis of clinical outcome and side effects in chemotherapy-naïve patients

scientific article published in January 2015

Chromogenic in situ hybridization is a reliable alternative to fluorescence in situ hybridization for diagnostic testing of 1p and 19q loss in paraffin-embedded gliomas

scientific article

Chronophin regulates active vitamin B6 levels and transcriptomic features of glioblastoma cell lines cultured under non-adherent, serum-free conditions.

scientific article

Clinical and immunological correlates of long term survival in glioblastoma.

scientific article

Clinical impact and functional aspects of tenascin-C expression during glioma progression

scientific article (publication date: 20 March 2002)

Clonal analysis in recurrent astrocytic, oligoastrocytic and oligodendroglial tumors implicates IDH1- mutation as common tumor initiating event

scientific article

Combined Treatment of ATRA with Epigenetic Drugs Increases Aggressiveness of Glioma Xenografts

scientific article published on April 2016

Comparative analysis of in vitro conditions for rat adult neural progenitor cells

scientific article published on 17 January 2007

Comparative analysis of transcriptomics based hypoxia signatures in head- and neck squamous cell carcinoma

scientific article

Comparative study of the novel RGD motif-containing ITGαvβ6 binding peptides SFLAP3 and SFITGv6 for diagnostic application in HNSCC.

scientific article published on 19 April 2018

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

article

Comprehensive Characterization of Cancer Driver Genes and Mutations

article

Comprehensive analysis of glycolytic enzymes as therapeutic targets in the treatment of glioblastoma

scientific article

Correlated MRI and Ultramicroscopy (MR-UM) of Brain Tumors Reveals Vast Heterogeneity of Tumor Infiltration and Neoangiogenesis in Preclinical Models and Human Disease

Cytogenetic characterization of head and neck squamous cell carcinoma cell lines as model systems for the functional analyses of tumor-associated genes

scientific article

DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis

scientific article published on 14 March 2017

DNA methylation-based classification of central nervous system tumours

scientific article published on 14 March 2018

Different angiogenic phenotypes in primary and secondary glioblastomas

scientific article published on May 2006

Differential genomic and proteomic profiling of glioblastoma cells exposed to terpyridineplatinum(II) complexes

scientific article

Differentiation therapy exerts antitumor effects on stem-like glioma cells

scientific article published on 4 May 2010

Discriminating expression of differentiation markers evolves in transplants of benign and malignant human skin keratinocytes through stromal interactions

scientific article published on July 2003

Dissecting the genomic complexity underlying medulloblastoma

scientific article

Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system

scientific article published on 24 October 2013

Effective Eradication of Glioblastoma Stem Cells by Local Application of an AC133/CD133-Specific T-cell-Engaging Antibody and CD8 T Cells

scientific article published on 3 April 2015

Effector T-cell infiltration positively impacts survival of glioblastoma patients and is impaired by tumor-derived TGF-β.

scientific article

Elimination of undifferentiated cancer cells by pluripotent stem cell inhibitors

scientific article published on 27 March 2014

Endothelial Cells Derived from Non-malignant Tissues Are of Limited Value as Models for Brain Tumor Vasculature

scientific article published on May 2015

Enzymatic assay for quantitative analysis of (D)-2-hydroxyglutarate

scientific article

Epigenetically mediated downregulation of the differentiation-promoting chaperon protein CRABP2 in astrocytic gliomas

scientific article published on 8 March 2012

Evaluation of drug transporters' significance for multidrug resistance in head and neck squamous cell carcinoma

scientific article published on 24 August 2010

Expansive growth of two glioblastoma stem-like cell lines is mediated by bFGF and not by EGF.

scientific article published on 08 October 2013

Expression and putative functions of GDF-15, a member of the TGF-beta superfamily, in human glioma and glioblastoma cell lines

scientific article

Expression and regulation of AC133 and CD133 in glioblastoma ⬇️

scientific article published on September 7, 2011

Expression of SGLT-1 in preneoplastic and neoplastic lesions of the head and neck

scientific article published on January 2004

Expression of nuclear receptor corepressors and class I histone deacetylases in astrocytic gliomas ⬇️

scientific article published on December 10, 2010

Expression profiles of angiogenic growth factors in squamous cell carcinomas of the head and neck

scientific article

FGFR1:TACC1 fusion is a frequent event in molecularly defined extraventricular neurocytoma.

scientific article

Farewell to oligoastrocytoma: in situ molecular genetics favor classification as either oligodendroglioma or astrocytoma

scientific article published on 21 August 2014

Feasibility of real-time molecular profiling for patients with newly diagnosed glioblastoma without MGMT promoter-hypermethylation - the NCT Neuro Master Match (N2M2) pilot study

scientific article published on 18 November 2017

Gain of 12p encompassing CCND2 is associated with gemistocytic histology in IDH mutant astrocytomas

scientific article published on 20 December 2016

Generation of “LYmph Node Derived Antibody Libraries” (LYNDAL) for selecting fully human antibody fragments with therapeutic potential

scientific article

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition

scientific article

Genomic and expression profiling of glioblastoma stem cell-like spheroid cultures identifies novel tumor-relevant genes associated with survival

scientific article published on 27 October 2009

Glutathione peroxidase 1 activity dictates the sensitivity of glioblastoma cells to oxidative stress ⬇️

scientific article published on August 1, 2012

Glycodelin as a Serum and Tissue Biomarker for Metastatic and Advanced NSCLC

article

Glycolysis and the pentose phosphate pathway are differentially associated with the dichotomous regulation of glioblastoma cell migration versus proliferation

scientific article published on 24 February 2016

Heparanase expression at the invasion front of human head and neck cancers and correlation with poor prognosis

scientific article

Histologically distinct neuroepithelial tumors with histone 3 G34 mutation are molecularly similar and comprise a single nosologic entity

scientific article published on 19 October 2015

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma

scientific article published in October 2012

Human papilloma virus (HPV) 18 proteins E6 and E7 up-regulate ABC transporters in oropharyngeal carcinoma. Involvement of the nonsense-mediated decay (NMD) pathway

scientific article published on 28 April 2018

Human papillomavirus 16 E6/E7-immortalized human gingival keratinocytes with epithelial mesenchymal transition acquire increased expression of cIAP-1, Bclx and p27(Kip1).

scientific article published in December 2009

IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO.

scientific article published on 12 May 2015

Identification and characterization of a peptide with affinity to head and neck cancer

scientific article

Identification of CRKII, CFL1, CNTN1, NME2, and TKT as Novel and Frequent T-Cell Targets in Human IDH-Mutant Glioma

scientific article published on 21 March 2018

Identification of Ligands and Translation to Clinical Applications

scientific article published in September 2017

Identification of T cell target antigens in glioblastoma stem-like cells using an integrated proteomics-based approach in patient specimens

scientific article published on 22 March 2017

Identification of a Novel ITGαvβ6-Binding Peptide Using Protein Separation and Phage Display

scientific article

Identification of a Prognostic Hypoxia-Associated Gene Set in IDH-Mutant Glioma

article

Immunotherapy response assessment in neuro-oncology: a report of the RANO working group

scientific article

In vitro responsiveness of glioma cell lines to multimodality treatment with radiotherapy, temozolomide, and epidermal growth factor receptor inhibition with cetuximab

scientific article published on July 2007

Increased Radiation-Associated T-Cell Infiltration in Recurrent IDH-Mutant Glioma

scientific article published on 21 October 2020

Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma

scientific article published on 10 July 2014

Integration and Comparison of Transcriptomic and Proteomic Data for Meningioma

scientific article published on 05 November 2020

Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas

scientific article published on 20 March 2017

LGR5 is a marker of poor prognosis in glioblastoma and is required for survival of brain cancer stem-like cells

scientific article published on 30 August 2012

LOC283731 promoter hypermethylation prognosticates survival after radiochemotherapy in IDH1 wild-type glioblastoma patients

scientific article

Label-free identification of the glioma stem-like cell fraction using Fourier-transform infrared spectroscopy

scientific article published on 25 March 2014

Lessons we learned from high-throughput and top-down systems biology analyses about glioma stem cells

scientific article published on January 2014

Location-Dependent Patient Outcome and Recurrence Patterns in IDH1-Wildtype Glioblastoma

Long noncoding RNA TARID directs demethylation and activation of the tumor suppressor TCF21 via GADD45A.

scientific article

Long-term outcome and survival of surgically treated supratentorial low-grade glioma in adult patients

scientific article

Long-term outcome and survival of surgically treated supratentorial low-grade glioma in adult patients

Loss of histone H3K27me3 identifies a subset of meningiomas with increased risk of recurrence

scientific article published on 7 April 2018

MBRS-12. INTERFERENCE WITH THE FUNCTION OF MYC IN GROUP 3 MEDULLOBLASTOMA.

scientific article published on 22 June 2018

MR-Class: A Python Tool for Brain MR Image Classification Utilizing One-vs-All DCNNs to Deal with the Open-Set Recognition Problem

scientific article published in 2023

Mechanistic studies on a novel, highly potent gold-phosphole inhibitor of human glutathione reductase

scientific article (publication date: 27 May 2005)

Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein

scientific article published on 11 April 2013

Meningiomas induced by low-dose radiation carry structural variants of NF2 and a distinct mutational signature

scientific article published on 4 May 2017

MetaboDiff: an R package for differential metabolomic analysis

scholarly article by Andreas Mock published in October 2018

Methylation-based classification of benign and malignant peripheral nerve sheath tumors

scientific article published on 8 February 2016

Microenvironment and brain tumor stem cell maintenance: impact of the niche

scientific article published on January 2014

Microglia isolated from patients with glioma gain antitumor activities on poly (I:C) stimulation

scientific article published on 20 October 2011

Microsatellite instability in pediatric and adult high-grade gliomas

scientific article published in April 2007

Minor role of pregnane-x-receptor for acquired multidrug resistance in head and neck squamous cell carcinoma in vitro

scientific article published on 12 March 2013

Mobile phone specific electromagnetic fields induce transient DNA damage and nucleotide excision repair in serum-deprived human glioblastoma cells.

scientific article published on 12 April 2018

Molecular dissection of the valproic acid effects on glioma cells

scientific article published on 18 August 2016

Molecular profiling of long-term survivors identifies a subgroup of glioblastoma characterized by chromosome 19/20 co-gain

scientific article published on May 2015

NIMG-56IMMUNOTHERAPY RESPONSE ASSESSMENT IN NEURO-ONCOLOGY (iRANO): A REPORT OF THE RANO WORKING GROUP.

scientific article

NKIM-6, a new immortalized human brain capillary endothelial cell line with conserved endothelial characteristics

scientific article published on 19 December 2006

Natural HLA class I ligands from glioblastoma: extending the options for immunotherapy ⬇️

scientific article published on December 23, 2012

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

scientific article

Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets

scientific article published on 15 December 2015

No prognostic value of IDH1 mutations in a series of 100 WHO grade II astrocytomas

scientific article published on 19 April 2012

Non-invasive glioblastoma immunoprofiling by printed peptide arrays

scientific article published on 12 August 2015

Novel anti-apoptotic microRNAs 582-5p and 363 promote human glioblastoma stem cell survival via direct inhibition of caspase 3, caspase 9, and Bim.

scientific article

Novel, improved grading system(s) for IDH-mutant astrocytic gliomas

scientific article published on 23 April 2018

Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo

scientific article published on 25 January 2017

Paracrine effects of mesenchymal stem cells induce senescence and differentiation of glioblastoma stem-like cells

scientific article published on 24 March 2015

Parvovirus H-1 infection of human glioma cells leads to complete viral replication and efficient cell killing

scientific article published on March 2004

Pediatric and Adult High-Grade Glioma Stem Cell Culture Models Are Permissive to Lytic Infection with Parvovirus H-1.

scientific article published on 19 May 2016

Potential CanonicalWntPathway Activation in High-Grade Astrocytomas ⬇️

scientific article published on August 2, 2012

Pre-clinical drug screen reveals topotecan, actinomycin D and volasertib as potential new therapeutic candidates for ETMR brain tumor patients

scientific article published on 08 May 2017

Printed peptide arrays identify prognostic TNC serumantibodies in glioblastoma patients

scientific article

Prognostic factors and long-term survival in surgically treated brain metastases from non-small cell lung cancer

scientific article published on 14 January 2016

Prognostic value of the extent of resection in supratentorial WHO grade II astrocytomas stratified for IDH1 mutation status: a single-center volumetric analysis

scientific article published on 25 June 2016

Proximity ligation assay evaluates IDH1R132H presentation in gliomas

scientific article

Quantification of retinoid concentrations in human serum and brain tumor tissues

scientific article published on 17 March 2012

Radiogenomics of Glioblastoma: Machine Learning-based Classification of Molecular Characteristics by Using Multiparametric and Multiregional MR Imaging Features

scientific article

Radiomic subtyping improves disease stratification beyond key molecular, clinical and standard imaging characteristics in patients with glioblastoma

scientific article published on 28 September 2017

Radiosensitivity of Patient-Derived Glioma Stem Cell 3-Dimensional Cultures to Photon, Proton, and Carbon Irradiation

scientific article published on 14 June 2015

Rapid T cell-based identification of human tumor tissue antigens by automated two-dimensional protein fractionation

scientific article

Rapid detection of 2-hydroxyglutarate in frozen sections of IDH mutant tumors by MALDI-TOF mass spectrometry.

scientific article

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

scientific article

Reduced promoter methylation and increased expression of CSPG4 negatively influences survival of HNSCC patients

scientific article

Retinoid resistance and multifaceted impairment of retinoic acid synthesis in glioblastoma

scientific article published on 6 May 2015

Role of NR1I2 (pregnane X receptor) polymorphisms in head and neck squamous cell carcinoma

scientific article published on 4 July 2015

Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations

scientific article

Spatial transcriptome analysis reveals Notch pathway-associated prognostic markers in IDH1 wild-type glioblastoma involving the subventricular zone

scientific article

Specific elimination of CD133+ tumor cells with targeted oncolytic measles virus

scientific article

Stem-cell-like glioma cells are resistant to TRAIL/Apo2L and exhibit down-regulation of caspase-8 by promoter methylation

scientific article published on 12 February 2009

Subgroup-specific localization of human medulloblastoma based on pre-operative MRI.

scientific article

TERT Promoter Mutations and Risk of Recurrence in Meningioma

scientific article published on 13 December 2015

Targeting atypical protein kinase C iota reduces viability in glioblastoma stem-like cells via a notch signaling mechanism

scientific article published on 14 June 2016

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

article

The Wnt secretion protein Evi/Gpr177 promotes glioma tumourigenesis

scientific article

The chromatin remodeler CHD7 regulates adult neurogenesis via activation of SoxC transcription factors

scientific article published in July 2013

The flavonoid kaempferol sensitizes human glioma cells to TRAIL-mediated apoptosis by proteasomal degradation of survivin

scientific article

The pregnane X receptor (PXR) and the nuclear receptor corepressor 2 (NCoR2) modulate cell growth in head and neck squamous cell carcinoma

scientific article published on 22 February 2018

The utility and limitations of neurosphere assay, CD133 immunophenotyping and side population assay in glioma stem cell research

scientific article published on 05 February 2010

Transcriptomic analysis of aggressive meningiomas identifies PTTG1 and LEPR as prognostic biomarkers independent of WHO grade

scientific article

Transmembrane protein CD9 is glioblastoma biomarker, relevant for maintenance of glioblastoma stem cells

scientific article published on 11 November 2015

Troglitazone-mediated sensitization to TRAIL-induced apoptosis is regulated by proteasome-dependent degradation of FLIP and ERK1/2-dependent phosphorylation of BAD.

scientific article

Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas.

scientific article published on 25 June 2009

Undressing of phosphine gold(I) complexes as irreversible inhibitors of human disulfide reductases

scientific article published on March 2006

VXM01 phase I study in patients with progressive glioblastoma: Final results

When Immune Cells Turn Bad-Tumor-Associated Microglia/Macrophages in Glioma.

scientific article published in February 2018

Yes and PI3K bind CD95 to signal invasion of glioblastoma

scientific article

Paulina is supported by:

About Paulina

Help