List of works - Nicholas A. Williamson

A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule

scientific article

A beacon of hope in stroke therapy-Blockade of pathologically activated cellular events in excitotoxic neuronal death as potential neuroprotective strategies

scientific article published on 17 February 2016

A modular BAM complex in the outer membrane of the alpha-proteobacterium Caulobacter crescentus.

scientific article

A novel strategy for the targeted analysis of protein and peptide metabolites

scientific article

A proteomic characterization shows differences in the milk fat globule membrane of buffalo and bovine milk

article by Hanh T.H. Nguyen et al published September 2017 in Food bioscience

A rigorous method to enrich for exosomes from brain tissue

scientific article published on 26 July 2017

A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition.

scientific article

A truncated fragment of Src protein kinase generated by calpain-mediated cleavage is a mediator of neuronal death in excitotoxicity

scientific article published on 11 February 2013

A type III effector antagonizes death receptor signalling during bacterial gut infection

scientific article published on September 2013

Aurora A phosphorylation of WD40-repeat protein 62 in mitotic spindle regulation.

scientific article published on 29 December 2015

Biologically active constituents of the secretome of human W8B2+ cardiac stem cells.

scientific article

C-terminal Src kinase-homologous kinase (CHK), a unique inhibitor inactivating multiple active conformations of Src family tyrosine kinases

scientific article

Changes in the Cytoplasmic Composition of Amino Acids and Proteins Observed in Staphylococcus aureus during Growth under Variable Growth Conditions Representative of the Human Wound Site

scientific article

Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations

scientific article

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Constraints within major histocompatibility complex class I restricted peptides: Presentation and consequences for T-cell recognition

scientific article published on 23 March 2010

Dafachronic acid promotes larval development in Haemonchus contortus by modulating dauer signalling and lipid metabolism

scientific article published on 23 July 2019

Deep proteomic profiling unveils arylsulfatase A as a non-alcoholic steatohepatitis inducible hepatokine and regulator of glycemic control

scientific article published on 10 March 2022

Defining the substrate specificity determinants recognized by the active site of C-terminal Src kinase-homologous kinase (CHK) and identification of β-synuclein as a potential CHK physiological substrate

scientific article

Direct quantitation of MHC-bound peptide epitopes by selected reaction monitoring

scientific article published on 20 May 2011

Disrupting assembly of the inner membrane complex blocks Plasmodium falciparum sexual stage development.

scientific article published on 6 October 2017

Dopamine promotes alpha-synuclein aggregation into SDS-resistant soluble oligomers via a distinct folding pathway

scientific article published on 9 June 2005

Dual requirement for a newly identified phosphorylation site in p70s6k

scientific article

Embryonic toxin expression in the cone snail Conus victoriae: primed to kill or divergent function?

scientific article published on 19 April 2011

Exploiting information inherent in binding sites of virus-specific antibodies: design of an HCV vaccine candidate cross-reactive with multiple genotypes.

scientific article published in January 2006

Expression and purification of the minor histocompatibility antigen, HA-1H generated in Escherichia coli

scientific article published on 27 February 2007

FunRich: An open access standalone functional enrichment and interaction network analysis tool

scientific article

Galectin-7 Impairs Placentation and Causes Preeclampsia Features in Mice

scientific article published on 31 August 2020

High throughput LC-MS/MS-based proteomic analysis of excretory-secretory products from short-term in vitro culture of Haemonchus contortus

article

Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity

scientific article

Identification of Conus peptidylprolyl cis-trans isomerases (PPIases) and assessment of their role in the oxidative folding of conotoxins

scientific article

Immune self-reactivity triggered by drug-modified HLA-peptide repertoire

scientific article

Interaction of the molecular chaperone alphaB-crystallin with alpha-synuclein: effects on amyloid fibril formation and chaperone activity

scientific article published in July 2004

Intersectin-1 interacts with the golgin GCC88 to couple the actin network and Golgi architecture

scientific article published on 12 December 2018

MR1 presents microbial vitamin B metabolites to MAIT cells

scientific article

Membrane-Enriched Proteomics Link Ribosome Accumulation and Proteome Reprogramming With Cold Acclimation in Barley Root Meristems

scientific article published on 30 April 2021

Modulation of conotoxin structure and function is achieved through a multienzyme complex in the venom glands of cone snails

scientific article

Modulation of the Catalytic Activity of the Src Family Tyrosine Kinase Hck by Autophosphorylation at a Novel Site in the Unique Domain

scientific article published in Journal of Biological Chemistry

Molecular alterations during larval development of Haemonchus contortus in vitro are under tight post-transcriptional control

article

Molecular markers of preterm labor in the choriodecidua

scientific article

Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation

scientific article

Operational Experience of an Open-Access, Subscription-Based Mass Spectrometry and Proteomics Facility

scientific article published on 3 January 2018

Opposing roles for JNK and Aurora A in regulating the association of WDR62 with spindle microtubules.

scientific article

Pancreatic Beta Cells Are Highly Susceptible to Oxidative and ER Stresses during the Development of Diabetes

article

Phosphorylated self-peptides alter human leukocyte antigen class I-restricted antigen presentation and generate tumor-specific epitopes

scientific article

Post-translational processing of rat ribosomal proteins. Ubiquitous methylation of Lys22 within the zinc-finger motif of RL40 (carboxy-terminal extension protein 52) and tissue-specific methylation of Lys4 in RL29.

scientific article published in June 1997

Proteasome-mediated degradation of the C-terminus of the Alzheimer's disease beta-amyloid protein precursor: effect of C-terminal truncation on production of beta-amyloid protein

scientific article published in November 2003

Proteomic interrogation of venom delivery in marine cone snails: novel insights into the role of the venom bulb

scientific article published on 29 September 2010

Quantitative lipidomic analysis of Ascaris suum

scientific article published on 02 December 2020

Quantitative proteomic analyses of dynamic signalling events in cortical neurons undergoing excitotoxic cell death

scientific article published on 01 March 2019

Refinement in the production and purification of recombinant HCMV IE1-pp65 protein for the generation of epitope-specific T cell immunity

scientific article published on 14 May 2008

Secreted HLA recapitulates the immunopeptidome and allows in-depth coverage of HLA A*02:01 ligands

scientific article published on 17 March 2012

Specialisation of the Venom Gland Proteome in Predatory Cone Snails Reveals Functional Diversification of the Conotoxin Biosynthetic Pathway

article

Species differences in the neuromuscular activity of post-synaptic neurotoxins from two Australian black snakes (Pseudechis porphyriacus and Pseudechis colletti).

scientific article published on 29 March 2013

Stable isotope shifted matrices enable the use of low mass ion precursor scanning for targeted metabolite identification

scientific article published on 17 January 2011

Structural insights into the multifunctionality of rabies virus P3 protein ⬇️

scientific article published on 29 March 2023

Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis

scientific article (publication date: 9 May 2003)

T cell determinants incorporating beta-amino acid residues are protease resistant and remain immunogenic in vivo

scientific article published on September 2005

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

scientific article

Tear Interferon-Gamma as a Biomarker for Evaporative Dry Eye Disease

scientific article published on September 2016

The A-chain of insulin is a hot-spot for CD4+ T cell epitopes in human type 1 diabetes.

scientific article published on 9 March 2009

The ataxin-1 interactome reveals direct connection with multiple disrupted nuclear transport pathways

scientific article published on 03 July 2020

The bacterial arginine glycosyltransferase effector NleB preferentially modifies Fas-associated death domain protein (FADD).

scientific article

The developmental lipidome of Haemonchus contortus

scientific article published on 01 September 2018

The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation

scientific article

The insulin A-chain epitope recognized by human T cells is posttranslationally modified

scientific article

The molecular basis of cross-reactivity in the Australian Snake Venom Detection Kit (SVDK).

scientific article published on 12 August 2007

The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain.

scientific article

The yeast homolog of mammalian ribosomal protein S30 is expressed from a duplicated gene without a ubiquitin-like protein fusion sequence. Evolutionary implications

scientific article published in June 1996

Tumors reveal their secrets to cytotoxic T cells

scholarly article

Use of proteomics to define targets of T-cell immunity

scientific article

Variability of allergens in commercial fish extracts for skin prick testing

scientific article published on 15 April 2019

List of works by Nicholas A. Williamson

A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule

A beacon of hope in stroke therapy-Blockade of pathologically activated cellular events in excitotoxic neuronal death as potential neuroprotective strategies

A modular BAM complex in the outer membrane of the alpha-proteobacterium Caulobacter crescentus.

A novel strategy for the targeted analysis of protein and peptide metabolites

A proteomic characterization shows differences in the milk fat globule membrane of buffalo and bovine milk

A rigorous method to enrich for exosomes from brain tissue

A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition.

A truncated fragment of Src protein kinase generated by calpain-mediated cleavage is a mediator of neuronal death in excitotoxicity

A type III effector antagonizes death receptor signalling during bacterial gut infection

Aurora A phosphorylation of WD40-repeat protein 62 in mitotic spindle regulation.

Biologically active constituents of the secretome of human W8B2+ cardiac stem cells.

C-terminal Src kinase-homologous kinase (CHK), a unique inhibitor inactivating multiple active conformations of Src family tyrosine kinases

Changes in the Cytoplasmic Composition of Amino Acids and Proteins Observed in Staphylococcus aureus during Growth under Variable Growth Conditions Representative of the Human Wound Site

Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Constraints within major histocompatibility complex class I restricted peptides: Presentation and consequences for T-cell recognition

Dafachronic acid promotes larval development in Haemonchus contortus by modulating dauer signalling and lipid metabolism

Deep proteomic profiling unveils arylsulfatase A as a non-alcoholic steatohepatitis inducible hepatokine and regulator of glycemic control

Defining the substrate specificity determinants recognized by the active site of C-terminal Src kinase-homologous kinase (CHK) and identification of β-synuclein as a potential CHK physiological substrate

Direct quantitation of MHC-bound peptide epitopes by selected reaction monitoring

Disrupting assembly of the inner membrane complex blocks Plasmodium falciparum sexual stage development.

Dopamine promotes alpha-synuclein aggregation into SDS-resistant soluble oligomers via a distinct folding pathway

Dual requirement for a newly identified phosphorylation site in p70s6k

Embryonic toxin expression in the cone snail Conus victoriae: primed to kill or divergent function?

Exploiting information inherent in binding sites of virus-specific antibodies: design of an HCV vaccine candidate cross-reactive with multiple genotypes.

Expression and purification of the minor histocompatibility antigen, HA-1H generated in Escherichia coli

FunRich: An open access standalone functional enrichment and interaction network analysis tool

Galectin-7 Impairs Placentation and Causes Preeclampsia Features in Mice

High throughput LC-MS/MS-based proteomic analysis of excretory-secretory products from short-term in vitro culture of Haemonchus contortus

Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity

Identification of Conus peptidylprolyl cis-trans isomerases (PPIases) and assessment of their role in the oxidative folding of conotoxins

Immune self-reactivity triggered by drug-modified HLA-peptide repertoire

Interaction of the molecular chaperone alphaB-crystallin with alpha-synuclein: effects on amyloid fibril formation and chaperone activity

Intersectin-1 interacts with the golgin GCC88 to couple the actin network and Golgi architecture

MR1 presents microbial vitamin B metabolites to MAIT cells

Membrane-Enriched Proteomics Link Ribosome Accumulation and Proteome Reprogramming With Cold Acclimation in Barley Root Meristems

Modulation of conotoxin structure and function is achieved through a multienzyme complex in the venom glands of cone snails

Modulation of the Catalytic Activity of the Src Family Tyrosine Kinase Hck by Autophosphorylation at a Novel Site in the Unique Domain

Molecular alterations during larval development of Haemonchus contortus in vitro are under tight post-transcriptional control

Molecular markers of preterm labor in the choriodecidua

Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation

Operational Experience of an Open-Access, Subscription-Based Mass Spectrometry and Proteomics Facility

Opposing roles for JNK and Aurora A in regulating the association of WDR62 with spindle microtubules.

Pancreatic Beta Cells Are Highly Susceptible to Oxidative and ER Stresses during the Development of Diabetes

Phosphorylated self-peptides alter human leukocyte antigen class I-restricted antigen presentation and generate tumor-specific epitopes

Post-translational processing of rat ribosomal proteins. Ubiquitous methylation of Lys22 within the zinc-finger motif of RL40 (carboxy-terminal extension protein 52) and tissue-specific methylation of Lys4 in RL29.

Proteasome-mediated degradation of the C-terminus of the Alzheimer's disease beta-amyloid protein precursor: effect of C-terminal truncation on production of beta-amyloid protein

Proteomic interrogation of venom delivery in marine cone snails: novel insights into the role of the venom bulb

Quantitative lipidomic analysis of Ascaris suum

Quantitative proteomic analyses of dynamic signalling events in cortical neurons undergoing excitotoxic cell death

Refinement in the production and purification of recombinant HCMV IE1-pp65 protein for the generation of epitope-specific T cell immunity

Secreted HLA recapitulates the immunopeptidome and allows in-depth coverage of HLA A*02:01 ligands

Specialisation of the Venom Gland Proteome in Predatory Cone Snails Reveals Functional Diversification of the Conotoxin Biosynthetic Pathway

Species differences in the neuromuscular activity of post-synaptic neurotoxins from two Australian black snakes (Pseudechis porphyriacus and Pseudechis colletti).

Stable isotope shifted matrices enable the use of low mass ion precursor scanning for targeted metabolite identification

Structural insights into the multifunctionality of rabies virus P3 protein ⬇️

Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis

T cell determinants incorporating beta-amino acid residues are protease resistant and remain immunogenic in vivo

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

Tear Interferon-Gamma as a Biomarker for Evaporative Dry Eye Disease

The A-chain of insulin is a hot-spot for CD4+ T cell epitopes in human type 1 diabetes.

The ataxin-1 interactome reveals direct connection with multiple disrupted nuclear transport pathways

The bacterial arginine glycosyltransferase effector NleB preferentially modifies Fas-associated death domain protein (FADD).

The developmental lipidome of Haemonchus contortus

The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation

The insulin A-chain epitope recognized by human T cells is posttranslationally modified

The molecular basis of cross-reactivity in the Australian Snake Venom Detection Kit (SVDK).

The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain.

The yeast homolog of mammalian ribosomal protein S30 is expressed from a duplicated gene without a ubiquitin-like protein fusion sequence. Evolutionary implications

Tumors reveal their secrets to cytotoxic T cells

Use of proteomics to define targets of T-cell immunity

Variability of allergens in commercial fish extracts for skin prick testing