List of works by Reuben J. Peters

1.55Å-resolution structure of ent-copalyl diphosphate synthase and exploration of general acid function by site-directed mutagenesis

scientific article

16-Aza-ent-beyerane and 16-Aza-ent-trachylobane: potent mechanism-based inhibitors of recombinant ent-kaurene synthase from Arabidopsis thaliana

scientific article published on 25 September 2007

18O2 labeling experiments illuminate the oxidation of ent-kaurene in bacterial gibberellin biosynthesis

scientific article published on 31 August 2017

A (conditional) role for labdane-related diterpenoid natural products in rice stomatal closure

scientific article published on 12 February 2021

A Pair of Residues That Interactively Affect Diterpene Synthase Product Outcome

scientific article published on 7 February 2017

A Tandem Array of ent-Kaurene Synthases in Maize with Roles in Gibberellin and More Specialized Metabolism

scientific article

A Third Class: Functional Gibberellin Biosynthetic Operon in Beta-Proteobacteria

scientific article published on 27 November 2018

A functional genomics approach to tanshinone biosynthesis provides stereochemical insights.

scientific article

A modular approach for facile biosynthesis of labdane-related diterpenes

scientific article published on 5 May 2007

A novel labda-7,13e-dien-15-ol-producing bifunctional diterpene synthase from Selaginella moellendorffii

scientific article

A single residue change leads to a hydroxylated product from the class II diterpene cyclization catalyzed by abietadiene synthase

scientific article published on 20 November 2012

A single residue switch converts abietadiene synthase into a pimaradiene specific cyclase.

scientific article published on December 2007

A single residue switch for Mg(2+)-dependent inhibition characterizes plant class II diterpene cyclases from primary and secondary metabolism

scientific article

Abietadiene synthase catalysis: conserved residues involved in protonation-initiated cyclization of geranylgeranyl diphosphate to (+)-copalyl diphosphate

scientific article (publication date: 12 February 2002)

Abietadiene synthase catalysis: mutational analysis of a prenyl diphosphate ionization-initiated cyclization and rearrangement

scientific article

Alternative termination chemistries utilized by monoterpene cyclases: chimeric analysis of bornyl diphosphate, 1,8-cineole, and sabinene synthases

scientific article

An operon for production of bioactive gibberellin A4 phytohormone with wide distribution in the bacterial rice leaf streak pathogen Xanthomonas oryzae pv. oryzicola.

scientific article published on 30 January 2017

An unexpected diterpene cyclase from rice: functional identification of a stemodene synthase

scientific article

Analysis of the Genome Sequence of the Medicinal Plant Salvia miltiorrhiza

scientific article

Anent-kaurene-derived diterpenoid virulence factor fromXanthomonas oryzaepv. oryzicola

scientific article published on 18 November 2014

Arginine in the FARM and SARM: A Role in Chain-Length Determination for Arginine in the Aspartate-Rich Motifs of Isoprenyl Diphosphate Synthases from

scientific article published on 6 October 2018

Author Correction: CYP72A enzymes catalyse 13-hydrolyzation of gibberellins

scientific article published on 01 November 2019

Author Correction: Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis

scientific article published on 15 October 2020

Bifunctional abietadiene synthase: free diffusive transfer of the (+)-copalyl diphosphate intermediate between two distinct active sites

scientific article (publication date: 19 September 2001)

Bifunctional abietadiene synthase: mutual structural dependence of the active sites for protonation-initiated and ionization-initiated cyclizations

scientific article

Biochemical characterization of the castor bean ent-kaurene synthase(-like) family supports quantum chemical view of diterpene cyclization

scientific article published on 5 May 2014

Biosynthesis of Diterpenoids in Tripterygium Adventitious Root Cultures

scientific article

Biosynthesis of lycosantalonol, a cis-prenyl derived diterpenoid

scientific article published on 21 November 2014

Biosynthesis of the diterpenoid lycosantalonol via nerylneryl diphosphate in Solanum lycopersicum

scientific article

Biosynthesis, elicitation and roles of monocot terpenoid phytoalexins

scientific article published on 26 March 2014

Blocking Deprotonation with Retention of Aromaticity in a Plant ent-Copalyl Diphosphate Synthase Leads to Product Rearrangement

scientific article

CYP701A8: a rice ent-kaurene oxidase paralog diverted to more specialized diterpenoid metabolism

scientific article published on 12 January 2012

CYP72A enzymes catalyse 13-hydrolyzation of gibberellins

scientific article published on 16 September 2019

CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables heterologous production of ferruginol in yeasts

scientific article published on 28 June 2013

CYP76M7 is an ent-cassadiene C11alpha-hydroxylase defining a second multifunctional diterpenoid biosynthetic gene cluster in rice

scientific article

CYP99A3: functional identification of a diterpene oxidase from the momilactone biosynthetic gene cluster in rice

scientific article

Catalytic Bases and Stereocontrol in Lamiaceae Class II Diterpene Cyclases

scientific article published in 2018

Changing Face: A Key Residue for the Addition of Water by Sclareol Synthase

article

Characterization and inhibition of a class II diterpene cyclase from Mycobacterium tuberculosis: implications for tuberculosis

scientific journal article

Characterization of CYP115 As a Gibberellin 3-Oxidase Indicates That Certain Rhizobia Can Produce Bioactive Gibberellin A4.

scientific article published on 15 February 2017

Characterization of CYP71Z18 indicates a role in maize zealexin biosynthesis

scientific article published on 12 October 2015

Characterization of CYP76AH4 clarifies phenolic diterpenoid biosynthesis in the Lamiaceae

scientific article published on 10 October 2013

Characterization of CYP76M5-8 indicates metabolic plasticity within a plant biosynthetic gene cluster

scientific article published on 3 January 2012

Characterization of an orphan diterpenoid biosynthetic operon from Salinispora arenicola ⬇️

scientific article published on 9 September 2014

Characterization of the kaurene oxidase CYP701A3, a multifunctional cytochrome P450 from gibberellin biosynthesis

scientific article published on November 2010

Combinatorial biosynthesis and the basis for substrate promiscuity in class I diterpene synthases

scientific article published on 17 June 2019

Combining metabolomics and transcriptomics to characterize tanshinone biosynthesis in Salvia miltiorrhiza

scientific article published on 28 January 2014

Conserved bases for the initial cyclase in gibberellin biosynthesis: from bacteria to plants

scientific article published on 24 September 2019

Cytochrome P450 promiscuity leads to a bifurcating biosynthetic pathway for tanshinones

scientific article published on 18 December 2015

Direct production of di-hydroxylated sesquiterpenoids by a maize terpene synthase.

scientific article published on 23 March 2018

Diterpene cyclases and the nature of the isoprene fold

scientific article (publication date: 15 August 2010)

Diterpenoid biopolymers: new directions for renewable materials engineering

scientific article (publication date: February 2011)

Diverging Mechanisms: Cytochrome-P450-Catalyzed Demethylation and γ-Lactone Formation in Bacterial Gibberellin Biosynthesis

Diverging Mechanisms: Cytochrome-P450-Catalyzed Demethylation and γ-Lactone Formation in Bacterial Gibberellin Biosynthesis

Doing the gene shuffle to close synteny: dynamic assembly of biosynthetic gene clusters

scientific article published on 20 May 2020

Domain loss has independently occurred multiple times in plant terpene synthase evolution

scientific article published on 17 October 2011

Edaxadiene: a new bioactive diterpene from Mycobacterium tuberculosis ⬇️

scientific journal article

Effect of isotopically sensitive branching on product distribution for pentalenene synthase: support for a mechanism predicted by quantum chemistry

scientific article

Efficient heterocyclisation by (di)terpene synthases

scientific article published on 27 July 2015

Electrostatic effects on (di)terpene synthase product outcome

scientific article published on 8 February 2011

Elucidation of gibberellin biosynthesis in bacteria reveals convergent evolution

scientific article published on 14 November 2016

Evident and latent plasticity across the rice diterpene synthase family with potential implications for the evolution of diterpenoid metabolism in the cereals ⬇️

scientific article

Extending a Single Residue Switch for Abbreviating Catalysis in Plant ent-Kaurene Synthases

scientific article published on 22 November 2016

Extreme promiscuity of a bacterial and a plant diterpene synthase enables combinatorial biosynthesis

scientific article published on 6 April 2016

Following evolution's lead to a single residue switch for diterpene synthase product outcome.

scholarly article

Full-length transcriptome sequences and splice variants obtained by a combination of sequencing platforms applied to different root tissues of Salvia miltiorrhiza and tanshinone biosynthesis.

scientific article

Functional Divergence of Diterpene Syntheses in the Medicinal Plant Salvia miltiorrhiza ⬇️

scientific article

Functional characterization and evolution of the isotuberculosinol operon in Mycobacterium tuberculosis and related Mycobacteria

scientific article published on 12 October 2012

Functional characterization of the rice kaurene synthase-like gene family

scientific article

Functional characterization of wheat copalyl diphosphate synthases sheds light on the early evolution of labdane-related diterpenoid metabolism in the cereals

scientific article published on 23 September 2012

Functional characterization of wheat ent-kaurene(-like) synthases indicates continuing evolution of labdane-related diterpenoid metabolism in the cereals

scientific article published on 22 September 2012

Functional conservation of the capacity for ent-kaurene biosynthesis and an associated operon in certain rhizobia

scientific article published on 18 October 2013

Functional identification of rice syn-copalyl diphosphate synthase and its role in initiating biosynthesis of diterpenoid phytoalexin/allelopathic natural products

scientific article

Genetic evidence for natural product-mediated plant-plant allelopathy in rice (Oryza sativa).

scientific article published on 12 December 2011

Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis

scientific article published on 20 February 2020

Gibberellin Phytohormone Metabolism

Gibberellin biosynthesis in bacteria: separate ent-copalyl diphosphate and ent-kaurene synthases in Bradyrhizobium japonicum

scientific article

Identification and functional characterization of diterpene synthases for triptolide biosynthesis from Tripterygium wilfordii ⬇️

scientific article

Identification of RoCYP01 (CYP716A155) enables construction of engineered yeast for high-yield production of betulinic acid

scientific article published on 15 July 2019

Identification of a Dolabellane Type Diterpene Synthase and other Root-Expressed Diterpene Synthases in Arabidopsis

scientific article published on 25 November 2016

Identification of syn-pimara-7,15-diene synthase reveals functional clustering of terpene synthases involved in rice phytoalexin/allelochemical biosynthesis

scientific article

Increasing complexity of a diterpene synthase reaction with a single residue switch

scientific article published on 26 March 2008

Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering

scientific article (publication date: February 2010)

Inferring Roles in Defense from Metabolic Allocation of Rice Diterpenoids.

scientific article published on 24 April 2018

Insights into Diterpene Cyclization from Structure of Bifunctional Abietadiene Synthase from Abies grandis

scientific article

Introducing selective agrochemical manipulation of gibberellin metabolism into a cereal crop

scientific article published on 03 February 2020

Investigating inducible short-chain alcohol dehydrogenases/reductases clarifies rice oryzalexin biosynthesis

scientific article published on 23 June 2016

Investigating the Phylogenetic Range of Gibberellin Biosynthesis in Bacteria

scientific article published on 20 April 2017

Investigating the conservation pattern of a putative second terpene synthase divalent metal binding motif in plants

scientific article published on 7 February 2009

Investigation of terpene diversification across multiple sequenced plant genomes

scientific article

Investigation of the Chemical Interface in the Soybean-Aphid and Rice-Bacteria Interactions Using MALDI-Mass Spectrometry Imaging.

scientific article published on 6 May 2015

Isoprenyl diphosphate synthases: the chain length determining step in terpene biosynthesis

scientific article published on 22 November 2018

Isotuberculosinol: the unusual case of an immunomodulatory diterpenoid from Mycobacterium tuberculosis

scientific article

Labeling Studies Clarify the Committed Step in Bacterial Gibberellin Biosynthesis.

scientific article

Magnesium depletion triggers production of an immune modulating diterpenoid in Mycobacterium tuberculosis

scientific journal article

Magnesium-specific ring expansion/contraction catalysed by the class II diterpene cyclase from pleuromutilin biosynthesis

scientific article published on 16 July 2020

Mechanism of abietadiene synthase catalysis: stereochemistry and stabilization of the cryptic pimarenyl carbocation intermediates

scientific article (publication date: 19 June 2002)

Mining of the <i>Catharanthus roseus</i> Genome Leads to Identification of a Biosynthetic Gene Cluster for Fungicidal Sesquiterpenes

scientific article published in 2021

Molecular Diversity of Terpene Synthases in the Liverwort Marchantia polymorpha

scientific article

Monoterpene biosynthesis pathway construction in Escherichia coli

scientific article published in September 2003

Novel product chemistry from mechanistic analysis of ent-copalyl diphosphate synthases from plant hormone biosynthesis

scientific article published on 23 May 2014

Optimization of recombinant expression enables discovery of novel cytochrome P450 activity in rice diterpenoid biosynthesis

scientific article published on 12 March 2015

Parsing a multifunctional biosynthetic gene cluster from rice: Biochemical characterization of CYP71Z6 & 7

scientific article

Picking sides: distinct roles for CYP76M6 and CYP76M8 in rice oryzalexin biosynthesis

scientific article published on September 2013

Premutilin Synthase: Ring Rearrangement by a Class II Diterpene Cyclase.

scientific article published in February 2018

Probing Labdane-Related Diterpenoid Biosynthesis in the Fungal Genus Aspergillus

scientific article published on 31 January 2017

Probing the Role of the DXDD Motif in Class II Diterpene Cyclases

scientific article published on 01 May 2007

Probing the promiscuity of ent-kaurene oxidases via combinatorial biosynthesis

scientific article published on 16 February 2016

Probing the specificity of CYP112 in bacterial gibberellin biosynthesis

scholarly article by Raimund Nagel published in July 2018

Product Rearrangement from Altering a Single Residue in the Rice syn-Copalyl Diphosphate Synthase ⬇️

scientific article published on 15 February 2016

Rice contains two disparate ent-copalyl diphosphate synthases with distinct metabolic functions

scientific article (publication date: December 2004)

Rv0989c encodes a novel (E)-geranyl diphosphate synthase facilitating decaprenyl diphosphate biosynthesis in Mycobacterium tuberculosis

scientific article

Structure and mechanism of the diterpene cyclase ent-copalyl diphosphate synthase

scientific article

Synergistic substrate inhibition of ent-copalyl diphosphate synthase: a potential feed-forward inhibition mechanism limiting gibberellin metabolism

article by Sladjana Prisic & Reuben J. Peters published May 2007 in Plant Physiology

Synthesis of (+/-)-nosyberkol (isotuberculosinol, revised structure of edaxadiene) and (+/-)-tuberculosinol

scientific article

Terpenoid synthase structures: a so far incomplete view of complex catalysis

scientific article

The application of synthetic biology to elucidation of plant mono-, sesqui-, and diterpenoid metabolism

scientific article published on 11 December 2014

The genome of the medicinal plant Andrographis paniculata provides insight into the biosynthesis of the bioactive diterpenoid neoandrographolide

scientific article published on 02 January 2019

The role of momilactones in rice allelopathy

scientific article published on 06 February 2013

The solution structure of the viral binding domain of Tva, the cellular receptor for subgroup A avian leukosis and sarcoma virus

scientific article

To gibberellins and beyond! Surveying the evolution of (di)terpenoid metabolism

scientific article

Two rings in them all: The labdane-related diterpenoids ⬇️

scientific article published on October 1, 2010

Uncovering the complex metabolic network underlying diterpenoid phytoalexin biosynthesis in rice and other cereal crop plants

article

Unraveling a Tangled Skein: Evolutionary Analysis of the Bacterial Gibberellin Biosynthetic Operon

scientific article published on 03 June 2020

Why are momilactones always associated with biosynthetic gene clusters in plants?

scientific article published on 02 June 2020

alpha-lytic protease precursor: characterization of a structured folding intermediate

scientific article published on April 1999

cis or trans with class II diterpene cyclases.

scientific article published in April 2017

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