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List of works by Hisashi Hemmi

(R)-mevalonate 3-phosphate is an intermediate of the mevalonate pathway in Thermoplasma acidophilum

scientific article published on 22 April 2014

(S)-2,3-Di-O-geranylgeranylglyceryl phosphate synthase from the thermoacidophilic archaeon Sulfolobus solfataricus. Molecular cloning and characterization of a membrane-intrinsic prenyltransferase involved in the biosynthesis of archaeal ether-linke

scientific article published on 8 September 2004

A Single Amino Acid Mutation Converts (R)-5-Diphosphomevalonate Decarboxylase into a Kinase.

scientific article published on 21 December 2016

A cis-prenyltransferase from Methanosarcina acetivorans catalyzes both head-to-tail and nonhead-to-tail prenyl condensation

scientific article published on 17 May 2016

A heteromeric cis-prenyltransferase is responsible for the biosynthesis of glycosyl carrier lipids in Methanosarcina mazei

scientific article published on 05 October 2019

A highly selective biosynthetic pathway to non-natural C50 carotenoids assembled from moderately selective enzymes

scientific article published on 14 July 2015

A new member of MocR/GabR-type PLP-binding regulator of D-alanyl-D-alanine ligase in Brevibacillus brevis

scientific article published on 17 August 2015

A novel geranylgeranyl reductase from the methanogenic archaeon Methanosarcina acetivorans displays unique regiospecificity.

scientific article

A novel zinc-dependent D-serine dehydratase from Saccharomyces cerevisiae.

scientific article

A phytoene desaturase homolog gene from the methanogenic archaeon Methanosarcina acetivorans is responsible for hydroxyarchaeol biosynthesis.

scientific article

Alicyclobacillus sendaiensis sp. nov., a novel acidophilic, slightly thermophilic species isolated from soil in Sendai, Japan.

scientific article

Alterations in D-amino acid concentrations and microbial community structures during the fermentation of red and white wines

scientific article published on 24 September 2010

Altering the substrate chain-length specificity of an alpha-glucosidase

scientific article published in May 2003

An active-site mutation causes enhanced reactivity and altered regiospecificity of transglucosylation catalyzed by the Bacillus sp. SAM1606 alpha-glucosidase

scientific article published on 01 January 2000

An alternative mechanism of product chain-length determination in type III geranylgeranyl diphosphate synthase

scientific article published in May 2003

Archaeal phospholipid biosynthetic pathway reconstructed in Escherichia coli.

scientific article

Bacillus subtilis spore coat protein LipC is a phospholipase B.

scientific article

Biochemical analysis of a novel lipolytic enzyme YvdO from Bacillus subtilis 168.

scientific article published on 7 April 2010

Biochemical evidence supporting the presence of the classical mevalonate pathway in the thermoacidophilic archaeon Sulfolobus solfataricus

scientific article

Biosynthetic machinery for C25,C25-diether archaeal lipids from the hyperthermophilic archaeon Aeropyrum pernix.

scientific article published on 7 February 2018

Catalytic mechanism of serine racemase from Dictyostelium discoideum

scientific article published on 27 December 2012

Catalytic mechanism of type 2 isopentenyl diphosphate:dimethylallyl diphosphate isomerase: verification of a redox role of the flavin cofactor in a reaction with no net redox change.

scientific article published in September 2004

Cloning, expression, and characterization of cis-polyprenyl diphosphate synthase from the thermoacidophilic archaeon Sulfolobus acidocaldarius

scientific article

Connected cavity structure enables prenyl elongation across the dimer interface in mutated geranylfarnesyl diphosphate synthase from Methanosarcina mazei

scientific article published on 08 May 2011

Conserved Pyridoxal 5'-Phosphate-Binding Protein YggS Impacts Amino Acid Metabolism through Pyridoxine 5'-Phosphate in Escherichia coli

scientific article published on 16 May 2019

Conserved pyridoxal protein that regulates Ile and Val metabolism

scientific article published on 4 October 2013

Construction of an artificial biosynthetic pathway for hyperextended archaeal membrane lipids in the bacterium <i>Escherichia coli</i>

scientific article published on 30 September 2020

Conversion from farnesyl diphosphate synthase to geranylgeranyl diphosphate synthase by random chemical mutagenesis.

scientific article published on April 1996

Conversion of Mevalonate 3-Kinase into 5-Phosphomevalonate 3-Kinase by Single Amino Acid Mutations

scientific article published on 18 April 2019

Conversion of product specificity of archaebacterial geranylgeranyl-diphosphate synthase. Identification of essential amino acid residues for chain length determination of prenyltransferase reaction.

scientific article published on August 1996

Covalent modification of reduced flavin mononucleotide in type-2 isopentenyl diphosphate isomerase by active-site-directed inhibitors

scientific article

D-Serine Metabolism and Its Importance in Development of Dictyostelium discoideum.

scientific article published on 24 April 2018

Deciphering the molecular basis of the broad substrate specificity of alpha-glucosidase from Bacillus sp. SAM1606.

scientific article published on October 2003

Domain characterization of Bacillus subtilis GabR, a pyridoxal 5'-phosphate-dependent transcriptional regulator.

scientific article

Effect of mutagenesis at the region upstream from the G(Q/E) motif of three types of geranylgeranyl diphosphate synthase on product chain-length

scientific article published in March 2009

Enzymatic assay for D-aspartic acid using D-aspartate oxidase and oxaloacetate decarboxylase

scientific article published on 07 November 2012

Fusion-type lycopene beta-cyclase from a thermoacidophilic archaeon Sulfolobus solfataricus

scientific article published in June 2003

Geranylfarnesyl diphosphate synthase from Methanosarcina mazei: Different role, different evolution.

scientific article

Geranylgeranyl Reductase and Ferredoxin from Methanosarcina acetivorans Are Required for the Synthesis of Fully Reduced Archaeal Membrane Lipid in Escherichia coli Cells

scientific article (publication date: 8 November 2013)

Geranylgeranyl reductase involved in the biosynthesis of archaeal membrane lipids in the hyperthermophilic archaeon Archaeoglobus fulgidus

scientific article published on 01 February 2007

Identification of enzymes involved in the mevalonate pathway of Flavobacterium johnsoniae.

scientific article published on 23 April 2017

Identification of genes affecting lycopene formation in Escherichia coli transformed with carotenoid biosynthetic genes: candidates for early genes in isoprenoid biosynthesis.

scientific article

In Vivo Formation of the Protein Disulfide Bond That Enhances the Thermostability of Diphosphomevalonate Decarboxylase, an Intracellular Enzyme from the Hyperthermophilic Archaeon Sulfolobus solfataricus.

scientific article published on 24 August 2015

Introduction of the archaebacterial geranylgeranyl pyrophosphate synthase gene into Chlamydomonas reinhardtii chloroplast

scientific article published in January 2003

Lysine racemase from a lactic acid bacterium, Oenococcus oeni: structural basis of substrate specificity

scientific article published on 03 October 2012

Menaquinone-specific prenyl reductase from the hyperthermophilic archaeon Archaeoglobus fulgidus

scientific article published on March 2005

Metal ion dependency of serine racemase from Dictyostelium discoideum

scientific article published on 5 February 2012

Modified mevalonate pathway of the archaeon Aeropyrum pernix proceeds via trans-anhydromevalonate 5-phosphate.

article published in the Proceedings of the National Academy of Sciences of the United States of America

Molecular biological analysis of microflora in a garbage treatment process under thermoacidophilic conditions

scientific article published in January 2004

Molecular cloning and characterization of a thermostable carboxylesterase from an archaeon, Sulfolobus shibatae DSM5389: non-linear kinetic behavior of a hormone-sensitive lipase family enzyme

scientific article published in January 2004

New Role of Flavin as a General Acid-Base Catalyst with No Redox Function in Type 2 Isopentenyl-diphosphate Isomerase

scientific article

Novel medium-chain prenyl diphosphate synthase from the thermoacidophilic archaeon Sulfolobus solfataricus

scientific article

Novel sugar phosphotransferase system applicable to the efficient labeling of the compounds synthesized via the non-mevalonate pathway in Escherichia coli

scientific article published in January 2002

Occurrence of the (2R,3S)-Isomer of 2-Amino-3,4-dihydroxybutanoic Acid in the Mushroom Hypsizygus marmoreus.

scientific article

Ophthalmic acid accumulation in an Escherichia coli mutant lacking the conserved pyridoxal 5'-phosphate-binding protein YggS.

scientific article published on 11 July 2016

Overexpression of an archaeal geranylgeranyl diphosphate synthase in Escherichia coli cells.

scientific article published in June 1998

PEGylated D-serine dehydratase as a D-serine reducing agent

scientific article published on 4 January 2015

Physiological role of carbon dioxide in spore germination of Clostridium perfringens S40.

scientific article published on 14 July 2009

Polymerase chain reaction-denaturing gradient gel electrophoresis analysis of microbial community structure in landfill leachate

scientific article

Production of ophthalmic acid using engineered Escherichia coli

scientific article published on 19 January 2018

Quantitative analyses of the behavior of exogenously added bacteria during an acidulocomposting process

scientific article published on 23 March 2012

Reaction mechanism of Zn2+-dependent d-serine dehydratase: role of a conserved tyrosine residue interacting with pyridine ring nitrogen of pyridoxal 5'-phosphate

scientific article published on 31 May 2014

Recognition of allylic substrates in Sulfolobus acidocaldarius geranylgeranyl diphosphate synthase: analysis using mutated enzymes and artificial allylic substrates

scientific article published on 01 June 1998

Reconstruction of the "Archaeal" Mevalonate Pathway from the Methanogenic Archaeon Methanosarcina mazei in Escherichia coli Cells

scientific article published on 02 March 2020

Role of the aminotransferase domain in Bacillus subtilis GabR, a pyridoxal 5'-phosphate-dependent transcriptional regulator

scientific article published on 08 December 2014

Simultaneous determination of D-amino acids by the coupling method of D-amino acid oxidase with high-performance liquid chromatography

scientific article published on 13 December 2010

Structure and mutation analysis of archaeal geranylgeranyl reductase

scientific article

Substrate specificity of undecaprenyl diphosphate synthase from the hyperthermophilic archaeon Aeropyrum pernix

scientific article published on 31 May 2013

The implication of YggT of Escherichia coli in osmotic regulation.

scientific article published on 7 December 2009

The product chain length determination mechanism of type II geranylgeranyl diphosphate synthase requires subunit interaction

scientific article published on 4 July 2008

The role of histidine-114 of Ssulfolobus acidocaldarius geranylgeranyl diphosphate synthase in chain-length determination

scientific article published on 01 September 2000

Total synthesis of geranylgeranylglyceryl phosphate enantiomers: substrates for characterization of 2,3-O-digeranylgeranylglyceryl phosphate synthase

scientific article published on March 2006

Type 2 isopentenyl diphosphate isomerase from a thermoacidophilic archaeon Sulfolobus shibatae

scientific article published in March 2004

UDP-glucuronic acid:anthocyanin glucuronosyltransferase from red daisy (Bellis perennis) flowers. Enzymology and phylogenetics of a novel glucuronosyltransferase involved in flower pigment biosynthesis.

scientific article

Utilization of an intermediate of the methylerythritol phosphate pathway, (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate, as the prenyl donor substrate for various prenyltransferases

scientific article

Zinc biosorption by a zinc-resistant bacterium, Brevibacterium sp. strain HZM-1.

scientific article published on October 2000