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List of works by Kyriakos E. Kypreos

ABCA1 promotes the de novo biogenesis of apolipoprotein CIII-containing HDL particles in vivo and modulates the severity of apolipoprotein CIII-induced hypertriglyceridemia

scientific article

Adenovirus mediated expression "in vivo" of the chemokine receptor CXCR1

scientific article published on 04 December 2008

Advances in high-density lipoprotein physiology: surprises, overturns, and promises

scientific article

Allele-dependent thermodynamic and structural perturbations in ApoE variants associated with the correction of dyslipidemia and formation of spherical ApoE-containing HDL particles.

scientific article published on 23 November 2012

ApoA1 Deficiency Reshapes the Phenotypic and Molecular Characteristics of Bone Marrow Adipocytes in Mice

scientific article published in 2022

ApoC-III deficiency prevents hyperlipidemia induced by apoE overexpression

scientific article published in May 2005

Apolipoprotein A-1 regulates osteoblast and lipoblast precursor cells in mice.

scientific article published on 18 April 2016

Apolipoprotein A-I modulates processes associated with diet-induced nonalcoholic fatty liver disease in mice

scientific article

Apolipoprotein E predisposes to obesity and related metabolic dysfunctions in mice

scientific article published on 27 August 2008

Association of the CETP Taq1B and LIPG Thr111Ile Polymorphisms with Glycated Hemoglobin and Blood Lipids in Newly Diagnosed Hyperlipidemic Patients

scientific article published on 30 August 2016

Basic fibroblast growth factor decreases type V/XI collagen expression in cultured bovine aortic smooth muscle cells ⬇️

scientific article published on February 1, 1998

Deficiency in apolipoprotein A-I ablates the pharmacological effects of metformin on plasma glucose homeostasis and hepatic lipid deposition.

scientific article

Deficiency in apolipoprotein E has a protective effect on diet-induced nonalcoholic fatty liver disease in mice

scientific article published on 02 August 2011

Distinct Roles of Apolipoproteins A1 and E in the Modulation of High-Density Lipoprotein Composition and Function.

scientific article published on 22 June 2016

Domains of apoE required for binding to apoE receptor 2 and to phospholipids: implications for the functions of apoE in the brain

scientific article

Domains of apolipoprotein E contributing to triglyceride and cholesterol homeostasis in vivo. Carboxyl-terminal region 203-299 promotes hepatic very low density lipoprotein-triglyceride secretion

scientific article

Effects of bariatric surgery on HDL structure and functionality: results from a prospective trial.

scientific article published on 21 May 2014

Fatty acid-related modulations of membrane fluidity in cells: detection and implications.

scientific article

Generation of a recombinant apolipoprotein E variant with improved biological functions: hydrophobic residues (LEU-261, TRP-264, PHE-265, LEU-268, VAL-269) of apoE can account for the apoE-induced hypertriglyceridemia

scientific article published on 2 December 2004

HDL biogenesis and functions: role of HDL quality and quantity in atherosclerosis

scientific article published on 06 June 2009

HDL quality and functionality: what can proteins and genes predict?

scientific article published on April 2014

High-density lipoprotein (HDL) metabolism and bone mass

scientific article published on 17 March 2017

Hyperlipidemia in APOE2 transgenic mice is ameliorated by a truncated apoE variant lacking the C-terminal domain.

scientific article published on 16 October 2002

Increased CUG triplet repeat-binding protein-1 predisposes to impaired adipogenesis with aging

scientific article published on 05 June 2006

LDL receptor deficiency or apoE mutations prevent remnant clearance and induce hypertriglyceridemia in mice

scientific article published on 7 December 2005

Lack of LCAT reduces the LPS-neutralizing capacity of HDL and enhances LPS-induced inflammation in mice.

scientific article published on 10 July 2015

Lecithin/cholesterol acyltransferase modulates diet-induced hepatic deposition of triglycerides in mice

scientific article published on 20 July 2012

Mechanisms of obesity and related pathologies

scientific article published on 15 September 2009

Mechanisms of obesity and related pathologies: role of apolipoprotein E in the development of obesity.

scientific article published on 15 September 2009

Molecular mechanisms of type III hyperlipoproteinemia: The contribution of the carboxy-terminal domain of ApoE can account for the dyslipidemia that is associated with the E2/E2 phenotype

scientific article published in August 2003

Pathway of biogenesis of apolipoprotein E-containing HDL in vivo with the participation of ABCA1 and LCAT.

scientific article published on April 2007

Perturbations in the HDL metabolic pathway predispose to the development of osteoarthritis in mice following long-term exposure to western-type diet

scientific article published on 11 November 2012

Pharmacodynamic and pharmacokinetic analysis of apoE4 [L261A, W264A, F265A, L268A, V269A], a recombinant apolipoprotein E variant with improved biological properties.

scientific article published on 14 September 2012

Pharmacological Management of Dyslipidemia in Atherosclerosis: Limitations, Challenges, and New Therapeutic Opportunities

scientific article published on 01 January 2018

Pleiotropic effects of apolipoprotein C3 on HDL functionality and adipose tissue metabolic activity.

scientific article published on 12 July 2017

Probing the pathways of chylomicron and HDL metabolism using adenovirus-mediated gene transfer.

scientific article published on April 2004

Qualitative characteristics of HDL in young patients of an acute myocardial infarction.

scientific article

Regulation of endothelial nitric oxide synthase and high-density lipoprotein quality by estradiol in cardiovascular pathology

scientific article published on 12 January 2014

Residues Leu261, Trp264, and Phe265 account for apolipoprotein E-induced dyslipidemia and affect the formation of apolipoprotein E-containing high-density lipoprotein.

scientific article published on 27 July 2007

SR-BI mediates cholesterol efflux via its interactions with lipid-bound ApoE. Structural mutations in SR-BI diminish cholesterol efflux

scientific article published on October 2005

Scavenger Receptor Class B Type I Regulates Plasma Apolipoprotein E Levels and Dietary Lipid Deposition to the Liver

scientific article published on 27 August 2015

Substitutions of glutamate 110 and 111 in the middle helix 4 of human apolipoprotein A-I (apoA-I) by alanine affect the structure and in vitro functions of apoA-I and induce severe hypertriglyceridemia in apoA-I-deficient mice

scientific article

Synchronization of cultured vascular smooth muscle cells following reversal of quiescence induced by treatment with the antioxidant N-acetylcysteine

scientific article published on 01 March 1998

Testosterone and cardiovascular disease: an old idea with modern clinical implications.

scientific article published on February 2011

The amino-terminal 1-185 domain of apoE promotes the clearance of lipoprotein remnants in vivo. The carboxy-terminal domain is required for induction of hyperlipidemia in normal and apoE-deficient mice.

scientific article

The aminoterminal 1-185 domain of human apolipoprotein E suffices for the de novo biogenesis of apoE-containing HDL-like particles in apoA-I deficient mice.

scientific article published on 14 July 2011

The hepatic uptake of VLDL in lrp-ldlr-/-vldlr-/- mice is regulated by LPL activity and involves proteoglycans and SR-BI

scientific article published on 26 March 2008

The low density lipoprotein receptor modulates the effects of hypogonadism on diet-induced obesity and related metabolic perturbations.

scientific article

Type V collagen regulates the assembly of collagen fibrils in cultures of bovine vascular smooth muscle cells.

scientific article published in September 2000

Τhe Antioxidant Function of HDL in Atherosclerosis

scientific article published on 11 June 2019

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