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List of works by Lars-Oliver Klotz

(-)-Epicatechin inhibits nitration and dimerization of tyrosine in hydrophilic as well as hydrophobic environments

scientific article published in December 2001

1,4-Naphthoquinones as inducers of oxidative damage and stress signaling in HaCaT human keratinocytes.

scientific article

1,4-naphthoquinones: from oxidative damage to cellular and inter-cellular signaling

scientific article

2-Methyl-1,4-naphthoquinone, vitamin K(3), decreases gap-junctional intercellular communication via activation of the epidermal growth factor receptor/extracellular signal-regulated kinase cascade.

scientific article published on September 2002

A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity

scientific article published on 11 September 2019

Activation of ErbB2 by 2-methyl-1,4-naphthoquinone (menadione) in human keratinocytes: role of EGFR and protein tyrosine phosphatases

scientific article

Activation of JNK and p38 but not ERK MAP kinases in human skin cells by 5-aminolevulinate-photodynamic therapy

scientific article published on October 1998

Activation pattern of mitogen-activated protein kinases elicited by peroxynitrite: attenuation by selenite supplementation

scientific article published on April 1999

Acute and long-term effects of arsenite in HepG2 cells: modulation of insulin signaling

scientific article published on 18 February 2014

Amphiphilic properties of (-)-epicatechin and their significance for protection of cells against peroxynitrite

scientific article published in July 2003

Arsenite-induced stress signaling: modulation of the phosphoinositide 3'-kinase/Akt/FoxO signaling cascade

scientific article published on 4 February 2013

Cellular adaptation to xenobiotics: Interplay between xenosensors, reactive oxygen species and FOXO transcription factors

scientific article published on 3 August 2017

Central role of Ferrous/Ferric iron in the ultraviolet B irradiation-mediated signaling pathway leading to increased interstitial collagenase (matrix-degrading metalloprotease (MMP)-1) and stromelysin-1 (MMP-3) mRNA levels in cultured human dermal f

scientific article published on 01 February 1998

Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy

scientific article published on May 2006

Comparing nitrosative versus oxidative stress toward zinc finger-dependent transcription. Unique role for NO.

scientific article published on 16 January 2002

Contribution of UVB and UVA to UV-dependent stimulation of cyclooxygenase-2 expression in artificial epidermis

scientific article published on 6 February 2004

Copper Homeostasis in the Model Organism C. elegans

scientific article published in 2024

Copper ions strongly activate the phosphoinositide-3-kinase/Akt pathway independent of the generation of reactive oxygen species

scientific article published in January 2002

Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162].

scientific article published on 26 October 2017

Critical role of L-arginine in endothelial cell survival during oxidative stress

scientific article published on 12 May 2003

Defenses against peroxynitrite

scientific article published on 01 January 1999

Defenses against peroxynitrite: selenocompounds and flavonoids.

scientific article

Detection of a functional xenobiotic response element in a widely employed FoxO-responsive reporter construct

scientific article published on 15 October 2011

Dicumarol is a potent reversible inhibitor of gap junctional intercellular communication

scientific article

Different susceptibility of malignant versus nonmalignant human T cells toward ultraviolet A-1 radiation-induced apoptosis

scientific article published on February 2004

Differential capability of metabolic substrates to promote hepatocellular lipid accumulation

scientific article published on 27 October 2018

Doxorubicin induces EGF receptor-dependent downregulation of gap junctional intercellular communication in rat liver epithelial cells

scientific article

Epicatechin selectively prevents nitration but not oxidation reactions of peroxynitrite

scientific article published in July 2001

Epidermal growth factor receptor is a common mediator of quinone-induced signaling leading to phosphorylation of connexin-43: role of glutathione and tyrosine phosphatases

scientific article published on 21 July 2003

Epidermal growth factor- and stress-induced loss of gap junctional communication is mediated by ERK-1/ERK-2 but not ERK-5 in rat liver epithelial cells

scientific article

Epigallocatechin gallate-induced modulation of FoxO signaling in mammalian cells and C. elegans: FoxO stimulation is masked via PI3K/Akt activation by hydrogen peroxide formed in cell culture

scientific article

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).

scientific article published on 18 May 2017

Evaluation of sulfur, selenium and tellurium catalysts with antioxidant potential

scientific article published on 4 November 2003

Evidence that singlet oxygen-induced human T helper cell apoptosis is the basic mechanism of ultraviolet-A radiation phototherapy.

scientific article

Extracellular generation of hydrogen peroxide is responsible for activation of EGF receptor by ultraviolet A radiation

scientific article published on 11 August 2006

FOXO1 cysteine-612 mediates stimulatory effects of the coregulators CBP and PGC1α on FOXO1 basal transcriptional activity

scientific article published on 02 March 2018

Flavonoids as Putative Inducers of the Transcription Factors Nrf2, FoxO, and PPARγ

scientific article

Free radicals and related reactive species as mediators of tissue injury and disease: implications for Health.

scientific article

Functional analysis of the glutathione S-transferase 3 from Onchocerca volvulus (Ov-GST-3): a parasite GST confers increased resistance to oxidative stress in Caenorhabditis elegans

scientific article published in January 2003

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

scientific journal article

Glutathione Peroxidase Protects against Peroxynitrite-mediated Oxidations

scientific article published in Journal of Biological Chemistry

Heavy metal ion-induced insulin-mimetic signaling.

scientific article published on January 2009

High efficiency of 5-aminolevulinate-photodynamic treatment using UVA irradiation

scientific article published in June 2001

Highlight: Oxidative Stress and Senescence

scientific article published on 01 March 2008

Highlight: xenobiotics and cell signaling

scientific article published on 01 November 2010

HuR regulates gap junctional intercellular communication by controlling beta-catenin levels and adherens junction integrity

scientific article

Identification of cytosolic leucyl aminopeptidase (EC 3.4.11.1) as the major cysteinylglycine-hydrolysing activity in rat liver

scientific article published in February 2003

Inhibition of heme oxygenase-1 partially reverses the arsenite-mediated decrease of CYP1A1, CYP1A2, CYP3A23, and CYP3A2 catalytic activity in isolated rat hepatocytes

scientific article published on 8 December 2011

Insulin suppresses the production of fibroblast growth factor 23 (FGF23)

article published in the Proceedings of the National Academy of Sciences of the United States of America

Insulin-like modulation of Akt/FoxO signaling by copper ions is independent of insulin receptor.

scientific article

Irradiation of cells with ultraviolet-A (320-400 nm) in the presence of cell culture medium elicits biological effects due to extracellular generation of hydrogen peroxide

scientific article published in April 2003

Label-free molecular mapping and assessment of glycogen in C. elegans

scientific article published on 01 March 2019

Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation.

scholarly article

Linking Alzheimer's disease to insulin resistance: the FoxO response to oxidative stress ⬇️

scientific article published on November 1, 2010

Loss of gap junctional intercellular communication in rat lung epithelial cells exposed to carbon or silica-based nanoparticles

scientific article published on November 2010

Loss of gap junctional intercellular communication in rat lung epithelial cells exposed to quartz particles

scientific article published on 18 September 2009

Loss of the tyrosyl radical in mouse ribonucleotide reductase by (-)-epicatechin

scientific article published in January 2005

Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanisms.

scientific article published on 24 October 2013

Mitogen-activated protein kinase (p38-, JNK-, ERK-) activation pattern induced by extracellular and intracellular singlet oxygen and UVA

scientific article published on 01 March 1999

Mitogen-activated protein kinase activation by singlet oxygen and ultraviolet A.

scientific article published on January 2000

Modifications of glyceraldehyde-3-phosphate dehydrogenase induced by increasing concentrations of peroxynitrite: early recognition by 20S proteasome

scientific article published in February 2003

Modulation of FoxO signaling in human hepatoma cells by exposure to copper or zinc ions

scientific article published on 30 August 2006

Modulation of cellular thiol status affects FoxO activity and life span.

scientific article published on October 2014

Multifaceted functions of the forkhead box transcription factors FoxO1 and FoxO3 in skin

scientific article published on 26 February 2017

Nickel and copper ion-induced stress signaling in human hepatoma cells: analysis of phosphoinositide 3'-kinase/Akt signaling.

scientific article published on 17 October 2008

Nitrotyrosine and protein carbonyls are equally distributed in HT22 cells after nitrosative stress.

scientific article published on 2 December 2006

Non-linear impact of glutathione depletion on C. elegans life span and stress resistance

scientific article published on 06 December 2016

Nuclear trapping of inactive FOXO1 by the Nrf2 activator diethyl maleate

scientific article published on 14 September 2018

Oxidative modification and nitration of human low-density lipoproteins by the reaction of hypochlorous acid with nitrite

scientific article published on July 1997

Peroxynitrite activates the phosphoinositide 3-kinase/Akt pathway in human skin primary fibroblasts

scientific article published on November 2000

Peroxynitrite signaling: receptor tyrosine kinases and activation of stress-responsive pathways.

scientific article

Peroxynitrite: From interception to signaling.

scientific article published on April 2016

Polyphenols of cocoa: inhibition of mammalian 15-lipoxygenase

scientific article published in December 2001

Posttranscriptional regulation of FOXO expression: microRNAs and beyond

scientific article published on 27 February 2016

Posttranscriptional regulation of connexin-43 expression.

scientific article published on 21 March 2012

Protection against peroxynitrite by selenoproteins

scientific article published in March 1998

Protection by organotellurium compounds against peroxynitrite-mediated oxidation and nitration reactions

scientific article published on 01 March 1998

Protein modification elicited by oxidized low-density lipoprotein (LDL) in endothelial cells: protection by (-)-epicatechin

scientific article published on 22 December 2006

Protein oxidation and proteolysis by the nonradical oxidants singlet oxygen or peroxynitrite

scientific article

Quinone-induced Cdc25A inhibition causes ERK-dependent connexin phosphorylation

scientific article published in February 2005

Rac upregulates tissue inhibitor of metalloproteinase-1 expression by redox-dependent activation of extracellular signal-regulated kinase signaling.

scientific article published on 19 September 2006

Reactivity of lipophilic diSchiff-Base coordinated copper in rat hepatocytes

scientific article published on 01 April 1996

Redox regulation of FoxO transcription factors

scientific article

Regulation of glucose-6-phosphatase gene expression by insulin and metformin.

scientific article

Reversible conversion of nitroxyl anion to nitric oxide

scientific article published on 01 January 2002

Role of copper, zinc, selenium and tellurium in the cellular defense against oxidative and nitrosative stress.

scientific article

Role of myoglobin in the antioxidant defense of the heart

scientific article

Selenenyl iodide: a new substrate for mammalian thioredoxin reductase

scientific article published in August 2003

Selenium-binding protein 1 (SELENBP1) is a marker of mature adipocytes

scientific article published on 10 November 2018

Selenoprotein P

scientific article published on 01 January 2002

Selenoprotein P protects low-density lipoprotein against oxidation.

scientific article published in February 2004

Selenoproteins: Antioxidant selenoenzymes and beyond

scientific article published on April 2016

Signal transduction, receptors, mediators and genes: younger than ever - the 13th meeting of the Signal Transduction Society focused on aging and immunology

scientific article

Signaling effects of menadione: from tyrosine phosphatase inactivation to connexin phosphorylation

scientific article published on January 2004

Singlet oxygen inactivates protein tyrosine phosphatase-1B by oxidation of the active site cysteine

scientific article published on 01 October 2006

Singlet oxygen mediates the activation of JNK by UVA radiation in human skin fibroblasts

scientific article published on 01 May 1997

Singlet oxygen-induced attenuation of growth factor signaling: possible role of ceramides

scientific article

Singlet oxygen-induced signaling effects in mammalian cells.

scientific article

Special Issue: cell-cell communication in development and disease

scientific article published on 01 August 2012

Stimulation of phosphoinositide 3-kinase/Akt signaling by copper and zinc ions: mechanisms and consequences.

scientific article published on 4 May 2007

Stress and biological aging: A double-edged sword.

scientific article

Sugar-derived AGEs accelerate pharyngeal pumping rate and increase the lifespan of Caenorhabditis elegans

scientific article published on 13 September 2019

Thalidomide resistance is based on the capacity of the glutathione-dependent antioxidant defense.

scientific article published in November 2008

The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan

scientific article published on 03 December 2019

Toxic and signaling effects of photochemically or chemically generated singlet oxygen in biological systems.

scientific article published on November 1997

Zinc fingers as biologic redox switches?

scientific article published on May 2009

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