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List of works by Ian C Wood

Alzheimer's disease: the potential of epigenetic treatments and current clinical candidates

scientific article published on 17 June 2020

BRG1 chromatin remodeling activity is required for efficient chromatin binding by repressor element 1-silencing transcription factor (REST) and facilitates REST-mediated repression

scientific article published on 4 October 2006

Binding and activation of the promoter for the neural cell adhesion molecule by Pax-8.

scientific article published on September 1994

Chromatin crosstalk in development and disease: lessons from REST

scientific article

Chromatin switching and transcriptional regulation in disease

scientific article published in August 2008

Differential tetraethylammonium sensitivity of KCNQ1-4 potassium channels

scientific article

Distinct RE-1 silencing transcription factor-containing complexes interact with different target genes

scientific article published on 15 October 2003

Dominant-negative subunits reveal potassium channel families that contribute to M-like potassium currents

scientific article published on 01 March 2002

Downregulated REST transcription factor is a switch enabling critical potassium channel expression and cell proliferation

scientific article published on October 2005

Elevated expression levels of miR-143/5 in saphenous vein smooth muscle cells from patients with Type 2 diabetes drive persistent changes in phenotype and function ⬇️

scientific article

Epigenetic mechanisms in development and disease

scientific article published in June 2013

Evolution of the vertebrate gene regulatory network controlled by the transcriptional repressor REST. ⬇️

scientific article

From Beads on a String to the Pearls of Regulation: the Structure and Dynamics of Chromatin

scientific article published on 01 April 2012

Gene expression in neuronal disease

scientific article published in December 2009

Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes

scientific journal article

Hypoxia-inducible factor-1α (HIF1α) switches on transient receptor potential ankyrin repeat 1 (TRPA1) gene expression via a hypoxia response element-like motif to modulate cytokine release

scientific article published on 26 July 2012

Identification of the REST regulon reveals extensive transposable element-mediated binding site duplication ⬇️

scientific article published on 09 August 2006

Identifying transcriptional regulatory regions using reporter genes and DNA-protein interactions by chromatin immunoprecipitation

scientific article published in January 2008

Inhibition of KCNQ1-4 potassium channels expressed in mammalian cells via M1 muscarinic acetylcholine receptors

scientific article

Inhibition of histone deacetylase 1 or 2 reduces induced cytokine expression in microglia through a protein synthesis independent mechanism ⬇️

scientific article published on 10 August 2017

Inhibition of histone deacetylase 1 or 2 reduces microglia activation through a gene expression independent mechanism

article

Interaction of the repressor element 1-silencing transcription factor (REST) with target genes

scientific article published on December 2003

K(v)1.5 potassium channel gene regulation by Sp1 transcription factor and oxidative stress

scientific article

KvDB; mining and mapping sequence variants in voltage-gated potassium channels

scientific article published in August 2010

Less REST, more vascular disease? Regulation of cell cycle and migration of vascular smooth muscle cells

scientific article

Mapping the methylation status of the miR-145 promoter in saphenous vein smooth muscle cells from individuals with type 2 diabetes ⬇️

scientific article published on 21 December 2016

Maternal Rest/Nrsf Regulates Zebrafish Behavior through snap25a/b. ⬇️

scientific article published on September 2016

MicroRNA-21 drives the switch to a synthetic phenotype in human saphenous vein smooth muscle cells ⬇️

scientific article published on 16 April 2018

Multiple chromatin modifications important for gene expression changes in cardiac hypertrophy

scientific article published in December 2006

Neural specific expression of the m4 muscarinic acetylcholine receptor gene is mediated by a RE1/NRSE-type silencing element

scientific article published on June 1996

Neuronal expression of the rat M1 muscarinic acetylcholine receptor gene is regulated by elements in the first exon

scientific article published on June 1999

One in the eye for herpes simplex virus

scientific article published in August 2002

Potent suppression of vascular smooth muscle cell migration and human neointimal hyperplasia by KV1.3 channel blockers

scientific article

Pro-inflammatory mechanisms of a non-steroidal anti-inflammatory drug

scientific article published on 01 March 2002

Regulation of gene expression in the nervous system

scientific article published on September 2008

Sharp wave-like activity in the hippocampus in vitro in mice lacking the gap junction protein connexin 36.

scientific article published in April 2003

Simvastatin inhibits TNFalpha-induced invasion of human cardiac myofibroblasts via both MMP-9-dependent and -independent mechanisms

scientific article published on 18 May 2007

Structure of the m1 muscarinic acetylcholine receptor gene and its promoter

scientific article published on July 1997

The repressor element 1-silencing transcription factor regulates heart-specific gene expression using multiple chromatin-modifying complexes

scientific article published on 19 March 2007

The transcriptional repressor REST is a critical regulator of the neurosecretory phenotype

scientific article published on September 2006

Transcriptional control of KCNQ channel genes and the regulation of neuronal excitability ⬇️

scientific article published on October 2010

Transcriptional repression of the M channel subunit Kv7.2 in chronic nerve injury

scientific article published on 23 February 2011

Uncovering combinatorial interactions in chromatin ⬇️

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