List of works - Antonio Rescifina

(+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties

scientific article published on 8 December 2017

3-Amino-2(5H)furanones as inhibitors of subgenomic hepatitis C virus RNA replication

scientific article published on 7 September 2008

3D-QSAR assisted identification of FABP4 inhibitors: An effective scaffold hopping analysis/QSAR evaluation

scientific article published on 29 November 2018

4-Nitro-2,1,3-benzoxadiazole derivatives as potential fluorescent sigma receptor probes

scholarly article in RSC Advances, vol. 5 no. 58, 2015

5'-Spiro-cyclopropanated lactose derivatives as suitable intermediates for the chain elongation: synthesis of a new 6-deoxy-6-methyl δ-eptulose

scientific article published on 25 January 2016

A Pseudouridine Isoxazolidinyl Nucleoside Analogue Structural Analysis: A Morphological Approach

A Rare Natural Benzo[k,l]xanthene as a Turn-Off Fluorescent Sensor for Cu2+ Ion

scientific article published on 21 September 2020

A Structure- and Ligand-Based Virtual Screening of a Database of "Small" Marine Natural Products for the Identification of "Blue" Sigma-2 Receptor Ligands

scientific article published on 14 October 2018

A molecular hybrid producing simultaneously singlet oxygen and nitric oxide by single photon excitation with green light

scientific article published on 20 December 2018

A top-down approach to crystal engineering of a racemic Δ2-isoxazoline

scientific article published on 16 January 2014

Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review.

scientific article

An Integrated Pharmacophore/Docking/3D-QSAR Approach to Screening a Large Library of Products in Search of Future Botulinum Neurotoxin A Inhibitors

scientific article published on 12 December 2020

Antiangiogenic Effect of (±)-Haloperidol Metabolite II Valproate Ester [(±)-MRJF22] in Human Microvascular Retinal Endothelial Cells

scientific article published on 25 October 2016

Biomimetic Synthesis of Natural and “Unnatural” Lignans by Oxidative Coupling of Caffeic Esters

scientific article from 2008

Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors

scientific article published on 21 September 2017

Computational Tools in the Discovery of FABP4 Ligands: A Statistical and Molecular Modeling Approach

scientific article published on 31 October 2019

Conversion of oximes to carbonyl compounds by triscetylpyridinium tetrakis(oxodiperoxotungsto) phosphate (PCWP)-mediated oxidation with hydrogen peroxide.

scientific article published in June 2008

Could N-(diethylcarbamothioyl)benzamide be a good ionophore for sensor membranes?

Crystal Morphologies and Polymorphs in Tolbutamide Microcrystalline Powder ⬇️

scientific article published on October 5, 2012

Cucurbit[7]uril as a catalytic nanoreactor for one-pot synthesis of isoxazolidines in water

scientific article published on 29 January 2020

DNA intercalators based on (1,10-phenanthrolin-2-yl)isoxazolidin-5-yl core with better growth inhibition and selectivity than cisplatin upon head and neck squamous cells carcinoma

scientific article published on 26 November 2017

Development of a Sigma-2 Receptor affinity filter through a Monte Carlo based QSAR analysis.

scientific article published on 29 May 2017

Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis

scientific article published on 27 August 2018

Diastereo- and enantioselective synthesis of 1'-C-branched N,O-nucleosides

scientific article published in May 2003

Discovery of High-Affinity Cannabinoid Receptors Ligands through a 3D-QSAR Ushered by Scaffold-Hopping Analysis

Discovery of benzimidazole-based L. mexicana cysteine protease CPB2.8ΔCTE inhibitors as potential therapeutics for leishmaniasis.

scientific article published on 4 May 2018

Enantioselective syntheses and cytotoxicity of N,O-nucleosides

scientific article

Ensemble-based ADME-Tox profiling and virtual screening for the discovery of new inhibitors of the Leishmania mexicana cysteine protease CPB2.8ΔCTE.

scientific article

Experimental and in silico characterization of a biologically active inosose

FABP4 inhibitors 3D-QSAR model and isosteric replacement of BMS309403 datasets

scientific article published on 19 December 2018

Fourfold Filtered Statistical/Computational Approach for the Identification of Imidazole Compounds as HO-1 Inhibitors from Natural Products

scientific article published on 12 February 2019

Functionalization of Single and Multi-Walled Carbon Nanotubes with Polypropylene Glycol Decorated Pyrrole for the Development of Doxorubicin Nano-Conveyors for Cancer Drug Delivery

scientific article published on 31 May 2020

Gemcitabine anticancer activity enhancement by water soluble celecoxib/sulfobutyl ether-β-cyclodextrin inclusion complex

scientific article published on 20 November 2018

Haloperidol metabolite II prodrug: asymmetric synthesis and biological evaluation on rat C6 glioma cells.

scientific article published on 6 November 2014

Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors.

scientific article published on 14 July 2017

How molecular interactions affect crystal morphology: The case of haloperidol ⬇️

scientific article published on 07 June 2011

Hydroxamic Acid-Based Histone Deacetylase (HDAC) Inhibitors Bearing a Pyrazole Scaffold and a Cinnamoyl Linker

scientific article published on 21 February 2019

Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands

scientific article published on 25 August 2017

Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region

scientific article published on 24 September 2020

Identification of potentially potent Heme Oxygenase-1 inhibitors through 3D-QSAR coupled to scaffold hopping analysis.

scientific article

Intramolecular Cycloadditions of α-Allyloxycarbonylnitrones: Stereoselective Synthesis of 3-Amino-2(5H)furanones

scientific article published on 01 June 2002

Isoxazolidinyl polycyclic aromatic hydrocarbons as DNA-intercalating antitumor agents.

scientific article published on 28 October 2010

Light-Controlled Simultaneous "On Demand" Release of Cytotoxic Combinations for Bimodal Killing of Cancer Cells

scientific article published on 30 March 2018

Mild Friedel-Crafts Reactions inside a Hexameric Resorcinarene Capsule: C-Cl Bond Activation through Hydrogen Bonding to Bridging Water Molecules.

scientific article published on 13 March 2018

Molecular modeling studies of pseudouridine isoxazolidinyl nucleoside analogues as potential inhibitors of the pseudouridine 5'-monophosphate glycosidase

scientific article

Morphing of Ibogaine: A Successful Attempt into the Search for Sigma-2 Receptor Ligands

scientific article published on 23 January 2019

New Anti SARS-Cov-2 Targets for Quinoline Derivatives Chloroquine and Hydroxychloroquine

scientific article published on 14 August 2020

New Arylethanolimidazole Derivatives as HO-1 Inhibitors with Cytotoxicity against MCF-7 Breast Cancer Cells

scientific article published on 11 March 2020

New rearrangement of 4-isoxazoline system: conversion of ketones into alpha,beta-unsaturated amides

scientific article published in May 2003

Novel Structural Insight into Inhibitors of Heme Oxygenase-1 (HO-1) by New Imidazole-Based Compounds: Biochemical and In Vitro Anticancer Activity Evaluation

scientific article published on 18 May 2018

Novel isoxazole polycyclic aromatic hydrocarbons as DNA-intercalating agents.

scientific article

Phosphonated carbocyclic 2'-oxa-3'-azanucleosides as new antiretroviral agents

scientific article

Physicochemical Characterization and Antioxidant Activity Evaluation of Idebenone/Hydroxypropyl-β-Cyclodextrin Inclusion Complex †

scientific article published on 25 September 2019

Potassium caffeate/caffeic acid co-crystal: the rat race between the catecholic and carboxylic moieties in an atypical co-crystal

scientific article published on 01 December 2012

Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors

scientific article published on 9 February 2018

Prevalence of oxetanose forms in the tautomeric equilibrium of β-hydroxy-1,5-dicarbonyl monosaccharides

scientific article published on 03 September 2013

Production of filmable medium-chain-length polyhydroxyalkanoates produced from glycerol by Pseudomonas mediterranea

scientific article published on 10 January 2014

Progress in the development of more effective and safer analgesics for pain management

scientific article published on 16 September 2019

Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application

scientific article published on 12 February 2019

Putative Inhibitors of SARS-CoV-2 Main Protease from A Library of Marine Natural Products: A Virtual Screening and Molecular Modeling Study

scientific article published on 23 April 2020

Recent advances in drug discovery of phototherapeutic non-porphyrinic anticancer agents.

scientific article

Recent advances in small organic molecules as DNA intercalating agents: synthesis, activity, and modeling.

scientific article published on 03 January 2014

Repurposing of FDA-Approved Drugs for Treating Iatrogenic Botulism: A Paired 3D-QSAR/Docking Approach†

scientific article published on 09 December 2019

Repurposing of Human Kinase Inhibitors in Neglected Protozoan Diseases.

scientific article

Repurposing of oxazolone chemistry: gaining access to functionalized graphene nanosheets in a top-down approach from graphite.

scientific article

S2RSLDB: a comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands

scientific article (publication date: 2017)

Self-catalyzed Mannich-type reaction of enolizable cyclic 1,3-dicarbonyls to acyclic nitrones: an entry to functionalized β-enamino diones

scientific article published on 04 April 2013

Serendipitous discovery of potent human head and neck squamous cell carcinoma anti-cancer molecules: A fortunate failure of a rational molecular design

scientific article published on 5 October 2017

Sigma-2 receptor ligands QSAR model dataset

scientific article published on 16 June 2017

Stereoselective Synthesis of 2'-Amino-2',3'-dideoxynucleosides by Nitrone 1,3-Dipolar Cycloaddition: A New Efficient Entry Toward d4T and Its 2-Methyl Analogue.

scientific article

Stereoselective synthesis and biological evaluations of novel 3'-deoxy-4'-azaribonucleosides as inhibitors of hepatitis C virus RNA replication

scientific article published on July 2009

Structural determinants of resveratrol for cell proliferation inhibition potency: experimental and docking studies of new analogs

scientific article published on 25 March 2010

Structure-Based Approach for the Prediction of Mu-opioid Binding Affinity of Unclassified Designer Fentanyl-Like Molecules. ⬇️

scientific article published on 10 May 2019

Synergic Interplay Between Halogen Bonding and Hydrogen Bonding in the Activation of a Neutral Substrate in a Nanoconfined Space

scientific article published on 27 November 2019

Synthesis and biological activity of isoxazolidinyl polycyclic aromatic hydrocarbons: potential DNA intercalators

scientific article published on January 2006

Synthesis and biological activity of novel bifunctional isoxazolidinyl polycyclic aromatic hydrocarbons.

scientific article

Synthesis and biological evaluation of phosphonated carbocyclic 2'-oxa-3'-aza-nucleosides

scientific article published on 5 October 2005

Synthesis and evaluation of haloperidol metabolite II prodrugs as anticancer agents.

scientific article published on 4 September 2017

Synthesis of C-4'truncated phosphonated carbocyclic 2'-oxa-3'-azanucleosides as antiviral agents.

scientific article

Synthesis of Rosmarinic Acid Amides as Antioxidative and Hypoglycemic Agents

scientific article published on 20 February 2019

Synthesis of phosphonated carbocyclic 2'-oxa-3'-aza-nucleosides: novel inhibitors of reverse transcriptase

scientific article

Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines

scientific article published on 17 September 2018

The Search for Potent, Small-Molecule HDACIs in Cancer Treatment: A Decade After Vorinostat.

scientific article published on 9 February 2017

Zinc(II) triflate-controlled 1,3-dipolar cycloadditions of C-(2-thiazolyl)nitrones: application to the synthesis of a novel isoxazolidinyl analogue of tiazofurin

scientific article published in October 2005

[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor

scientific article published on 10 September 2019

β-cyclodextrin and caffeine complexes with natural polyphenols from olive and olive oils: NMR, thermodynamic, and molecular modeling studies

scientific article published on 3 November 2010

γ-Cyclodextrin as a Catalyst for the Synthesis of 2-Methyl-3,5-diarylisoxazolidines in Water.

scientific article published on 13 April 2017

List of works by Antonio Rescifina

(+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties

3-Amino-2(5H)furanones as inhibitors of subgenomic hepatitis C virus RNA replication

3D-QSAR assisted identification of FABP4 inhibitors: An effective scaffold hopping analysis/QSAR evaluation

4-Nitro-2,1,3-benzoxadiazole derivatives as potential fluorescent sigma receptor probes

5'-Spiro-cyclopropanated lactose derivatives as suitable intermediates for the chain elongation: synthesis of a new 6-deoxy-6-methyl δ-eptulose

A Pseudouridine Isoxazolidinyl Nucleoside Analogue Structural Analysis: A Morphological Approach

A Rare Natural Benzo[k,l]xanthene as a Turn-Off Fluorescent Sensor for Cu2+ Ion

A Structure- and Ligand-Based Virtual Screening of a Database of "Small" Marine Natural Products for the Identification of "Blue" Sigma-2 Receptor Ligands

A molecular hybrid producing simultaneously singlet oxygen and nitric oxide by single photon excitation with green light

A top-down approach to crystal engineering of a racemic Δ2-isoxazoline

Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review.

An Integrated Pharmacophore/Docking/3D-QSAR Approach to Screening a Large Library of Products in Search of Future Botulinum Neurotoxin A Inhibitors

Antiangiogenic Effect of (±)-Haloperidol Metabolite II Valproate Ester [(±)-MRJF22] in Human Microvascular Retinal Endothelial Cells

Biomimetic Synthesis of Natural and “Unnatural” Lignans by Oxidative Coupling of Caffeic Esters

Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors

Computational Tools in the Discovery of FABP4 Ligands: A Statistical and Molecular Modeling Approach

Conversion of oximes to carbonyl compounds by triscetylpyridinium tetrakis(oxodiperoxotungsto) phosphate (PCWP)-mediated oxidation with hydrogen peroxide.

Could N-(diethylcarbamothioyl)benzamide be a good ionophore for sensor membranes?

Crystal Morphologies and Polymorphs in Tolbutamide Microcrystalline Powder ⬇️

Cucurbit[7]uril as a catalytic nanoreactor for one-pot synthesis of isoxazolidines in water

DNA intercalators based on (1,10-phenanthrolin-2-yl)isoxazolidin-5-yl core with better growth inhibition and selectivity than cisplatin upon head and neck squamous cells carcinoma

Development of a Sigma-2 Receptor affinity filter through a Monte Carlo based QSAR analysis.

Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis

Diastereo- and enantioselective synthesis of 1'-C-branched N,O-nucleosides

Discovery of High-Affinity Cannabinoid Receptors Ligands through a 3D-QSAR Ushered by Scaffold-Hopping Analysis

Discovery of benzimidazole-based L. mexicana cysteine protease CPB2.8ΔCTE inhibitors as potential therapeutics for leishmaniasis.

Enantioselective syntheses and cytotoxicity of N,O-nucleosides

Ensemble-based ADME-Tox profiling and virtual screening for the discovery of new inhibitors of the Leishmania mexicana cysteine protease CPB2.8ΔCTE.

Experimental and in silico characterization of a biologically active inosose

FABP4 inhibitors 3D-QSAR model and isosteric replacement of BMS309403 datasets

Fourfold Filtered Statistical/Computational Approach for the Identification of Imidazole Compounds as HO-1 Inhibitors from Natural Products

Functionalization of Single and Multi-Walled Carbon Nanotubes with Polypropylene Glycol Decorated Pyrrole for the Development of Doxorubicin Nano-Conveyors for Cancer Drug Delivery

Gemcitabine anticancer activity enhancement by water soluble celecoxib/sulfobutyl ether-β-cyclodextrin inclusion complex

Haloperidol metabolite II prodrug: asymmetric synthesis and biological evaluation on rat C6 glioma cells.

Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors.

How molecular interactions affect crystal morphology: The case of haloperidol ⬇️

Hydroxamic Acid-Based Histone Deacetylase (HDAC) Inhibitors Bearing a Pyrazole Scaffold and a Cinnamoyl Linker

Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands

Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region

Identification of potentially potent Heme Oxygenase-1 inhibitors through 3D-QSAR coupled to scaffold hopping analysis.

Intramolecular Cycloadditions of α-Allyloxycarbonylnitrones: Stereoselective Synthesis of 3-Amino-2(5H)furanones

Isoxazolidinyl polycyclic aromatic hydrocarbons as DNA-intercalating antitumor agents.

Light-Controlled Simultaneous "On Demand" Release of Cytotoxic Combinations for Bimodal Killing of Cancer Cells

Mild Friedel-Crafts Reactions inside a Hexameric Resorcinarene Capsule: C-Cl Bond Activation through Hydrogen Bonding to Bridging Water Molecules.

Molecular modeling studies of pseudouridine isoxazolidinyl nucleoside analogues as potential inhibitors of the pseudouridine 5'-monophosphate glycosidase

Morphing of Ibogaine: A Successful Attempt into the Search for Sigma-2 Receptor Ligands

New Anti SARS-Cov-2 Targets for Quinoline Derivatives Chloroquine and Hydroxychloroquine

New Arylethanolimidazole Derivatives as HO-1 Inhibitors with Cytotoxicity against MCF-7 Breast Cancer Cells

New rearrangement of 4-isoxazoline system: conversion of ketones into alpha,beta-unsaturated amides

Novel Structural Insight into Inhibitors of Heme Oxygenase-1 (HO-1) by New Imidazole-Based Compounds: Biochemical and In Vitro Anticancer Activity Evaluation

Novel isoxazole polycyclic aromatic hydrocarbons as DNA-intercalating agents.

Phosphonated carbocyclic 2'-oxa-3'-azanucleosides as new antiretroviral agents

Physicochemical Characterization and Antioxidant Activity Evaluation of Idebenone/Hydroxypropyl-β-Cyclodextrin Inclusion Complex †

Potassium caffeate/caffeic acid co-crystal: the rat race between the catecholic and carboxylic moieties in an atypical co-crystal

Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors

Prevalence of oxetanose forms in the tautomeric equilibrium of β-hydroxy-1,5-dicarbonyl monosaccharides

Production of filmable medium-chain-length polyhydroxyalkanoates produced from glycerol by Pseudomonas mediterranea

Progress in the development of more effective and safer analgesics for pain management

Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application

Putative Inhibitors of SARS-CoV-2 Main Protease from A Library of Marine Natural Products: A Virtual Screening and Molecular Modeling Study

Recent advances in drug discovery of phototherapeutic non-porphyrinic anticancer agents.

Recent advances in small organic molecules as DNA intercalating agents: synthesis, activity, and modeling.

Repurposing of FDA-Approved Drugs for Treating Iatrogenic Botulism: A Paired 3D-QSAR/Docking Approach†

Repurposing of Human Kinase Inhibitors in Neglected Protozoan Diseases.

Repurposing of oxazolone chemistry: gaining access to functionalized graphene nanosheets in a top-down approach from graphite.

S2RSLDB: a comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands

Self-catalyzed Mannich-type reaction of enolizable cyclic 1,3-dicarbonyls to acyclic nitrones: an entry to functionalized β-enamino diones

Serendipitous discovery of potent human head and neck squamous cell carcinoma anti-cancer molecules: A fortunate failure of a rational molecular design

Sigma-2 receptor ligands QSAR model dataset

Stereoselective Synthesis of 2'-Amino-2',3'-dideoxynucleosides by Nitrone 1,3-Dipolar Cycloaddition: A New Efficient Entry Toward d4T and Its 2-Methyl Analogue.

Stereoselective synthesis and biological evaluations of novel 3'-deoxy-4'-azaribonucleosides as inhibitors of hepatitis C virus RNA replication

Structural determinants of resveratrol for cell proliferation inhibition potency: experimental and docking studies of new analogs

Structure-Based Approach for the Prediction of Mu-opioid Binding Affinity of Unclassified Designer Fentanyl-Like Molecules. ⬇️

Synergic Interplay Between Halogen Bonding and Hydrogen Bonding in the Activation of a Neutral Substrate in a Nanoconfined Space

Synthesis and biological activity of isoxazolidinyl polycyclic aromatic hydrocarbons: potential DNA intercalators

Synthesis and biological activity of novel bifunctional isoxazolidinyl polycyclic aromatic hydrocarbons.

Synthesis and biological evaluation of phosphonated carbocyclic 2'-oxa-3'-aza-nucleosides

Synthesis and evaluation of haloperidol metabolite II prodrugs as anticancer agents.

Synthesis of C-4'truncated phosphonated carbocyclic 2'-oxa-3'-azanucleosides as antiviral agents.