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List of works by Fook Tim Chew

17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use

scientific article published on 09 July 2018

A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus

scientific article published on 20 February 2017

A functional brain-derived neurotrophic factor (BDNF) gene variant increases the risk of moderate-to-severe allergic rhinitis

scientific article

A high-risk airway mycobiome is associated with frequent exacerbation and mortality in COPD

scientific article published on 24 September 2020

A luminance- and contrast-invariant edge-similarity measure

scientific article published in December 2006

A practical genome-enabled legitimacy assay for oil palm breeding and seed production

scientific article published on 05 November 2019

A systematic review of skin ageing genes: gene pleiotropy and genes on the chromosomal band 16q24.3 may drive skin ageing

scientific article published in 2022

ATF5, a possible regulator of osteogenic differentiation in human adipose-derived stem cells

scientific article published on 01 August 2012

Age- and sex-related changes in lymphocyte subpopulations of healthy Asian subjects: from birth to adulthood

scientific article published in March 1996

Allergen Atlas: a comprehensive knowledge center and analysis resource for allergen information.

scientific article published on 11 February 2009

Allergenic differences between the domestic mites Blomia tropicalis and Dermatophagoides pteronyssinus.

scientific article

Allergens and their associated small molecule ligands-their dual role in sensitization

scientific article published in August 2021

Allergic airway diseases in a tropical urban environment are driven by dominant mono-specific sensitization against house dust mites.

scientific article

Association of ambient air-pollution levels with acute asthma exacerbation among children in Singapore

scientific article published in April 1999

Association of interleukin-13 SNP rs20541 (Arg>Gln) to allergic rhinitis in an Asian population of ethnic Chinese in Singapore

scientific article published on 15 August 2013

Associations between home dampness and presence of molds with asthma and allergic symptoms among young children in the tropics.

scientific article published on August 2007

Asthma and TNF variants in Chinese and Malays

article

BIM is a prognostic biomarker for early prednisolone response in pediatric acute lymphoblastic leukemia.

scientific article published on 2 December 2010

Bla g 3: a novel allergen of German cockroach identified using cockroach-specific avian single-chain variable fragment antibody

scientific article published on 5 December 2013

Bla g 6: a troponin C allergen from Blattella germanica with IgE binding calcium dependence.

scientific article published on 2 May 2006

Blo t 2: Group 2 allergen from the dust mite Blomia tropicalis

scientific article published on 22 August 2019

Characterization of Der f 22 - a paralogue of the major allergen Der f 2

scientific article published in Scientific Reports

Characterization of Osteogenically Induced Adipose Tissue-Derived Precursor Cells in 2-Dimensional and 3-Dimensional Environments

scientific article published on 01 January 2006

Characterizing haploinsufficiency of SHELL gene to improve fruit form prediction in introgressive hybrids of oil palm

scientific article

Clinicopathological significance of calreticulin in breast invasive ductal carcinoma.

scientific article

Cloning, expression, purification, characterization, crystallization and X-ray crystallographic analysis of recombinant Der f 21 (rDer f 21) from Dermatophagoides farinae.

scientific article published on 23 October 2015

Cloning, expression, purification, crystallization and preliminary X-ray diffraction studies of a major group 7 allergen, Der f 7, from the dust mite Dermatophagoides farinae

scientific article published on 26 November 2011

Conformational IgE Epitope Mapping of Der p 2 and the Evaluations of Two Candidate Hypoallergens for Immunotherapy.

scientific article published on 21 February 2018

Crystal Structure of Der f 7, a Dust Mite Allergen from Dermatophagoides farinae

scientific article

Crystal structure and epitope analysis of house dust mite allergen Der f 21

scientific article published on 20 March 2019

Detection of two orchid viruses using quartz crystal microbalance (QCM) immunosensors

scientific article published on 01 January 2002

Determinants of indoor allergens in tropical child care centers.

scientific article published on 12 January 2008

Development and Validation of a High-Density SNP Genotyping Array for African Oil Palm.

scientific article

Different phenotypes and factors associated with atopic dermatitis in the young adult Singaporean Chinese population: A cross-sectional study

article

Differential abundance analysis of mesocarp protein from high- and low-yielding oil palms associates non-oil biosynthetic enzymes to lipid biosynthesis

scientific article

Differential gene expression at different stages of mesocarp development in high- and low-yielding oil palm.

scientific article

Differential metabolite profiles during fruit development in high-yielding oil palm mesocarp.

scientific article

Distinct 'Immuno-Allertypes' of Disease and High Frequencies of Sensitisation in Non-Cystic-Fibrosis Bronchiectasis

scientific article published on 01 April 2019

Diurnal biomarkers reveal key photosynthetic genes associated with increased oil palm yield

article

Edible “bird's nest”–induced anaphylaxis: An under-recognized entity?

scientific article published on 01 August 2000

Elevation of human alpha-defensins and S100 calcium-binding proteins A8 and A9 in tear fluid of patients with pterygium.

scientific article

Environmental fungal sensitisation associates with poorer clinical outcomes in COPD

scientific article published on 27 April 2020

Epidemiology of allergic rhinitis and associated risk factors in Asia

article

Epistasis between phenylethanolamine N-methyltransferase and β2-adrenergic receptor influences extracellular epinephrine level and associates with the susceptibility to allergic asthma

scientific article published on 15 January 2020

Evaluating the transferability of Hapmap SNPs to a Singapore Chinese population

scientific article

Evaluation of methods and marker Systems in Genomic Selection of oil palm (Elaeis guineensis Jacq.).

scientific article published on 11 December 2017

Exonic mutations associated with atopic dermatitis disrupt lympho-epithelial Kazal-type related inhibitor action and enhance its degradation

scientific article published on 09 September 2019

Functional variants of 17q12-21 are associated with allergic asthma but not allergic rhinitis

scientific article published on 16 October 2015

Genetic analysis of an allergic rhinitis cohort reveals an intercellular epistasis between FAM134B and CD39.

scientific article

Genetic susceptibility to asthma and atopy among Chinese in Singapore - linkage to markers on chromosome 5q31-33

article

Genetic variants of inducible costimulator are associated with allergic asthma susceptibility

scientific article published on 7 August 2014

Genetic variation in BDNF is associated with allergic asthma and allergic rhinitis in an ethnic Chinese population in Singapore

scientific article

Genome-wide association study identifies PERLD1 as asthma candidate gene

scientific article

Genome-wide association study identifies three key loci for high mesocarp oil content in perennial crop oil palm.

scientific article

Genome-wide association study of Parkinson's disease in East Asians

scientific article

Genome-wide association study of asthma exacerbations despite inhaled corticosteroids use

scientific article published on 10 December 2020

Genomic Selection in Commercial Perennial Crops: Applicability and Improvement in Oil Palm (Elaeis guineensis Jacq.).

scientific article

Geographical comparison of the prevalence of childhood asthma and allergies in Singapore

scientific article published in December 1999

Global Allergy Forum and 3rd Davos Declaration 2015: Atopic dermatitis/Eczema: challenges and opportunities toward precision medicine

scientific article

Home air-conditioning, traffic exposure, and asthma and allergic symptoms among preschool children

scientific article

Home and day-care microenvironment exposure to Blomia tropicalis allergens and their associations with salivary eosinophilic cationic protein (ECP) among preschool children in Singapore

scientific article published on 17 July 2019

Home exposures to environmental tobacco smoke and allergic symptoms among young children in Singapore

scientific article published on 14 December 2007

Homologous Lympho-Epithelial Kazal-type Inhibitor Domains Delay Blood Coagulation by Inhibiting Factor X and XI with Differential Specificity

scientific article published on 12 July 2018

House dust mite fauna of tropical Singapore.

scientific article

Identification of prognostic protein biomarkers in childhood acute lymphoblastic leukemia (ALL).

scientific article published on 21 March 2011

Immunological corollary of the pulmonary mycobiome in bronchiectasis: the CAMEB study

scientific article published on 27 July 2018

Interleukin-13 genetic variants, household carpet use and childhood asthma

scientific article

Interleukin-4 receptor variant Q576R: ethnic differences and association with atopy

scientific article published on 01 October 1999

International consensus (ICON) on: clinical consequences of mite hypersensitivity, a global problem

scientific article

Investigating the effects of preinduction on human adipose-derived precursor cells in an athymic rat model

scientific article published in December 2006

Key glycolytic branch influences mesocarp oil content in oil palm

scientific article published on 29 August 2017

Laboratory assessment of the efficiency of encasing materials against house dust mites and their allergens

scientific article published in October 2003

Linkage disequilibrium pattern in asthma candidate genes from 5q31-q33 in the Singapore Chinese population

scientific article published on 8 January 2010

Mite component–specific IgE repertoire and phenotypes of allergic disease in childhood: The tropical perspective ⬇️

scientific article published on March 1, 2011

Molecular engineering of a therapeutic antibody for Blo t 5-induced allergic asthma

scientific article published on 3 December 2016

Multiple wheat flour allergens and cross-reactive carbohydrate determinants bind IgE in baker's asthma.

scientific article

Multiplexed genotyping of ABC transporter polymorphisms with the Bioplex suspension array.

scientific article

NMR Structure and IgE Epitopes of Blo t 21, a Major Dust Mite Allergen from Blomia tropicalis

scientific article

Patterns of IgE sensitization in house dust mite-allergic patients: implications for allergen immunotherapy.

scientific article published on 20 October 2015

Pharmacogenomic associations of adverse drug reactions in asthma: systematic review and research prioritisation

scientific article published on 17 January 2020

Piezoelectric quartz crystal based label-free analysis for allergy disease

scientific article published on 01 January 2000

Production and Proteomic Characterization of Pharmaceutical-Grade Dermatophagoides pteronyssinus and Dermatophagoides farinae Extracts for Allergy Vaccines

scientific article published on 01 June 2006

Profiling of metabolites in oil palm mesocarp at different stages of oil biosynthesis

scientific article published on 18 February 2013

Proteomic analysis of human tears: defensin expression after ocular surface surgery.

scientific article

Proteomic analysis of rabbit tear fluid: Defensin levels after an experimental corneal wound are correlated to wound closure

scientific article

Proteomic analysis of the oil palm fruit mesocarp reveals elevated oxidative phosphorylation activity is critical for increased storage oil production

scientific article

Proteomics technology and therapeutics.

scientific article

Replication of genome-wide association study loci for allergic rhinitis and house dust mite sensitization in an Asian population of ethnic Chinese in Singapore

scientific article published on 8 December 2012

Resurgence of measles in Singapore: profile of hospital cases

scientific article published in October 1999

Seasonal trends of viral respiratory tract infections in the tropics ⬇️

scientific article published on August 1, 1998

Self-Assembled Monolayer-Based Piezoelectric Crystal Immunosensor for the Quantification of Total Human Immunoglobulin E

scientific article published on 01 August 1999

Sensitization to Aspergillus species is associated with frequent exacerbations in severe asthma.

scientific article

Sensitization to local dust-mite fauna in Singapore

scientific article published in November 1999

Sensitization to oil palm pollen associates with risks and severity of allergic diseases

scientific article published in 2024

Severe acute respiratory syndrome coronavirus and viral mimicry

scientific article published in June 2003

Singapore's haze and acute asthma in children

scientific article published in The Lancet

Structural basis for the bacterial membrane insertion of dermcidin peptide, DCD-1L.

scientific article published on 24 October 2017

Survival of childhood leukemia in Singapore

scientific article published on 01 May 1996

Systematic characterization of basophil anergy

scientific article

Systematic review of the epidemiology of acne vulgaris

scientific article published on 01 April 2020

TRANSPARENT TESTA GLABRA1 Regulates the Accumulation of Seed Storage Reserves in Arabidopsis.

scientific article

The Asthma-associated PER1-like domain-containing protein 1 (PERLD1) Haplotype Influences Soluble Glycosylphosphatidylinositol Anchor Protein (sGPI-AP) Levels in Serum and Immune Cell Proliferation

scientific article published on 20 January 2020

The effect of ventilation strategies of child care centers on indoor air quality and respiratory health of children in Singapore

article

The major allergen Der p 2 is a cholesterol binding protein

scientific article published in Scientific Reports

The major cockroach allergen Bla g 4 binds tyramine and octopamine

scientific article

The upper and lower airway responses to nasal challenge with house-dust mite Blomia tropicalis

scientific article

Time trends and seasonal variation in acute childhood asthma in tropical Singapore ⬇️

scientific article published on February 1, 1998

Under-recognition of childhood asthma in Singapore: evidence from a questionnaire survey

scientific article published in March 1999

Validation of GWAS Loci for Atopic Dermatitis in a Singapore Chinese Population

article

Validation of pooled genotyping on the Affymetrix 500 k and SNP6.0 genotyping platforms using the polynomial-based probe-specific correction

scientific article

Variation in Uteroglobin-Related Protein 1 (UGRP1) gene is associated with allergic rhinitis in Singapore Chinese.

scientific article

Viability and adipogenic potential of human adipose tissue processed cell population obtained from pump-assisted and syringe-assisted liposuction.

scientific article

Whole metagenome profiling reveals skin microbiome-dependent susceptibility to atopic dermatitis flare

scientific article published on 11 July 2016

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