List of works - Nadia Naffakh

A genetically engineered waterfowl influenza virus with a deletion in the stalk of the neuraminidase has increased virulence for chickens.

scientific article

Advances in Analyzing Virus-Induced Alterations of Host Cell Splicing

scientific article published on 19 December 2018

April 2009: an outbreak of swine-origin influenza A(H1N1) virus with evidence for human-to-human transmission

scientific article published on 13 May 2009

Avian Influenza A virus polymerase association with nucleoprotein, but not polymerase assembly, is impaired in human cells during the course of infection

scientific article

CD36-specific antibodies block release of HIV-1 from infected primary macrophages and its transmission to T cells.

scientific article

Cloning of the chicken RNA polymerase I promoter and use for reverse genetics of influenza A viruses in avian cells

scientific article published on November 2005

Codon conservation in the influenza A virus genome defines RNA packaging signals

scientific article

Cold-sensitivity of polymerase complexes from human or avian influenza A viruses

Comparative Analysis of the Ability of the Polymerase Complexes of Influenza Viruses Type A, B and C to Assemble into Functional RNPs that Allow Expression and Replication of Heterotypic Model RNA Templates In Vivo

article

Comparative Profiling of Ubiquitin Proteasome System Interplay with Influenza A Virus PB2 Polymerase Protein Recapitulating Virus Evolution in Humans.

scientific article published on 22 November 2017

Confronting influenza virus: a common but ever-changing pathogen

scientific article

Delivery of therapeutic proteins from genetically-modified cells

scientific article

Differential effect of nucleotide substitutions in the 3' arm of the influenza A virus vRNA promoter on transcription/replication by avian and human polymerase complexes is related to the nature of PB2 amino acid 627.

scientific article published on November 2002

Enhancement of the influenza A hemagglutinin (HA)-mediated cell-cell fusion and virus entry by the viral neuraminidase (NA).

scientific article

Experimental Approaches to Study Genome Packaging of Influenza A Viruses

scientific article

Exploration of binary virus-host interactions using an infectious protein complementation assay

scientific article published on July 2013

Expression of a foreign gene by stable recombinant influenza viruses harboring a dicistronic genomic segment with an internal promoter

article

Failure of zanamivir therapy for pneumonia in a bone-marrow transplant recipient infected by a zanamivir-sensitive influenza A (H1N1) virus.

scientific article

Gene transfer for erythropoiesis enhancement

scientific article published on August 1996

Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations

scientific article

Genetic analysis of the compatibility between polymerase proteins from human and avian strains of influenza A viruses

scientific article published in May 2000

HMGB1 protein binds to influenza virus nucleoprotein and promotes viral replication

scientific article

Hemagglutinin residues of recent human A(H3N2) influenza viruses that contribute to the inability to agglutinate chicken erythrocytes

scientific article

Hemagglutinin residues of recent human A(H3N2) viruses that affect agglutination of chicken erythrocytes

Host restriction of avian influenza viruses at the level of the ribonucleoproteins.

scientific article

Host-range determinants on the PB2 protein of influenza A viruses control the interaction between the viral polymerase and nucleoprotein in human cells

scientific article published on 31 January 2007

In vitro characterization of naturally occurring influenza H3NA- viruses lacking the NA gene segment: toward a new mechanism of viral resistance?

scientific article published on September 2010

Influenza A Virus Polymerase Recruits the RNA Helicase DDX19 to Promote the Nuclear Export of Viral mRNAs

scientific article published on 22 September 2016

Influenza A virus neuraminidase enhances meningococcal adhesion to epithelial cells through interaction with sialic acid-containing meningococcal capsules

scientific article published on 15 June 2009

Influenza A virus progeny vRNP trafficking in live infected cells studied with the virus-encoded fluorescently tagged PB2 protein

scientific article

Influenza virus polymerase subunits co-evolve to ensure proper levels of dimerization of the heterotrimer

scientific article published on 03 October 2019

Length variations in the NA stalk of an H7N1 influenza virus have opposite effects on viral excretion in chickens and ducks.

scientific article published on 19 October 2011

Long-term control of erythropoietin secretion by doxycycline in mice transplanted with engineered primary myoblasts

scientific article

Metal-Tagging Transmission Electron Microscopy and Immunogold Labeling on Tokuyasu Cryosections to Image Influenza A Virus Ribonucleoprotein Transport and Packaging

article

Multiple hosts and Influenza A viruses genetic mixing

scientific article published on 01 December 2013

Mutations Conferring Increased Sensitivity to Tripartite Motif 22 Restriction Accumulated Progressively in the Nucleoprotein of Seasonal Influenza A (H1N1) Viruses between 1918 and 2009.

scientific article published on 4 April 2018

Neuraminidase of 2007-2008 influenza A(H1N1) viruses shows increased affinity for sialic acids due to the D344N substitution

scientific article published on January 2011

Neuraminidase stalk length and additional glycosylation of the hemagglutinin influence the virulence of influenza H5N1 viruses for mice

scientific article published on 18 February 2009

Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase

scientific article

Productive infection of human skeletal muscle cells by pandemic and seasonal influenza A(H1N1) viruses.

scientific article

Recombinant influenza A viruses harboring optimized dicistronic NA segment with an extended native 5' terminal sequence: induction of heterospecific B and T cell responses in mice

scientific article published on 3 November 2005

Recruitment of RED-SMU1 complex by Influenza A Virus RNA polymerase to control Viral mRNA splicing

scientific article

Replication-competent influenza A virus that encodes a split-green fluorescent protein-tagged PB2 polymerase subunit allows live-cell imaging of the virus life cycle

scientific article

Residue 627 of PB2 is a determinant of cold sensitivity in RNA replication of avian influenza viruses.

scientific article published on June 2001

Resistance Development to Influenza Virus Sialidase Inhibitors

article

Sensitivity of H5N1 influenza viruses to oseltamivir: an update

Shortening the unstructured, interdomain region of the non-structural protein NS1 of an avian H1N1 influenza virus increases its replication and pathogenicity in chickens

scientific article

Structural basis of an essential interaction between influenza polymerase and Pol II CTD.

scientific article published on 21 December 2016

Synthesis and evaluation of novel 3-C-alkylated-Neu5Ac2en derivatives as probes of influenza virus sialidase 150-loop flexibility

scientific article

Targeting host calpain proteases decreases influenza A virus infection.

scientific article

Temperature-Sensitive Mutants in the Influenza A Virus RNA Polymerase: Alterations in the PA Linker Reduce Nuclear Targeting of the PB1-PA Dimer and Result in Viral Attenuation

scientific article published on 8 April 2015

The RBPome of influenza A virus NP-mRNA reveals a role for TDP-43 in viral replication

scientific article published in 2024

The Transcription/Replication Activity of the Polymerase of Influenza A Viruses Is Not Correlated with the Level of Proteolysis Induced by the PA Subunit

article published in 2001

The generation of recombinant influenza A viruses expressing a PB2 fusion protein requires the conservation of a packaging signal overlapping the coding and noncoding regions at the 5' end of the PB2 segment

scientific article

The influenza A virus NS1 protein interacts with the nucleoprotein of viral ribonucleoprotein complexes

scientific article published on 16 March 2011

The influenza fingerprints: NS1 and M1 proteins contribute to specific host cell ultrastructure signatures upon infection by different influenza A viruses.

scientific article

Time-Resolved Visualisation of Nearly-Native Influenza A Virus Progeny Ribonucleoproteins and Their Individual Components in Live Infected Cells

scientific article (publication date: 2016)

Transplantation of adult-derived myoblasts in mice following gene transfer

scientific article published in September 1993

[Interspecies transmission, adaptation to humans and pathogenicity of animal influenza viruses].

scientific article

List of works by Nadia Naffakh

A genetically engineered waterfowl influenza virus with a deletion in the stalk of the neuraminidase has increased virulence for chickens.

Advances in Analyzing Virus-Induced Alterations of Host Cell Splicing

April 2009: an outbreak of swine-origin influenza A(H1N1) virus with evidence for human-to-human transmission

Avian Influenza A virus polymerase association with nucleoprotein, but not polymerase assembly, is impaired in human cells during the course of infection

CD36-specific antibodies block release of HIV-1 from infected primary macrophages and its transmission to T cells.

Cloning of the chicken RNA polymerase I promoter and use for reverse genetics of influenza A viruses in avian cells

Codon conservation in the influenza A virus genome defines RNA packaging signals

Cold-sensitivity of polymerase complexes from human or avian influenza A viruses

Comparative Analysis of the Ability of the Polymerase Complexes of Influenza Viruses Type A, B and C to Assemble into Functional RNPs that Allow Expression and Replication of Heterotypic Model RNA Templates In Vivo

Comparative Profiling of Ubiquitin Proteasome System Interplay with Influenza A Virus PB2 Polymerase Protein Recapitulating Virus Evolution in Humans.

Confronting influenza virus: a common but ever-changing pathogen

Delivery of therapeutic proteins from genetically-modified cells

Differential effect of nucleotide substitutions in the 3' arm of the influenza A virus vRNA promoter on transcription/replication by avian and human polymerase complexes is related to the nature of PB2 amino acid 627.

Enhancement of the influenza A hemagglutinin (HA)-mediated cell-cell fusion and virus entry by the viral neuraminidase (NA).

Experimental Approaches to Study Genome Packaging of Influenza A Viruses

Exploration of binary virus-host interactions using an infectious protein complementation assay

Expression of a foreign gene by stable recombinant influenza viruses harboring a dicistronic genomic segment with an internal promoter

Failure of zanamivir therapy for pneumonia in a bone-marrow transplant recipient infected by a zanamivir-sensitive influenza A (H1N1) virus.

Gene transfer for erythropoiesis enhancement

Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations

Genetic analysis of the compatibility between polymerase proteins from human and avian strains of influenza A viruses

HMGB1 protein binds to influenza virus nucleoprotein and promotes viral replication

Hemagglutinin residues of recent human A(H3N2) influenza viruses that contribute to the inability to agglutinate chicken erythrocytes

Hemagglutinin residues of recent human A(H3N2) viruses that affect agglutination of chicken erythrocytes

Host restriction of avian influenza viruses at the level of the ribonucleoproteins.

Host-range determinants on the PB2 protein of influenza A viruses control the interaction between the viral polymerase and nucleoprotein in human cells

In vitro characterization of naturally occurring influenza H3NA- viruses lacking the NA gene segment: toward a new mechanism of viral resistance?

Influenza A Virus Polymerase Recruits the RNA Helicase DDX19 to Promote the Nuclear Export of Viral mRNAs

Influenza A virus neuraminidase enhances meningococcal adhesion to epithelial cells through interaction with sialic acid-containing meningococcal capsules

Influenza A virus progeny vRNP trafficking in live infected cells studied with the virus-encoded fluorescently tagged PB2 protein

Influenza virus polymerase subunits co-evolve to ensure proper levels of dimerization of the heterotrimer

Length variations in the NA stalk of an H7N1 influenza virus have opposite effects on viral excretion in chickens and ducks.

Long-term control of erythropoietin secretion by doxycycline in mice transplanted with engineered primary myoblasts

Metal-Tagging Transmission Electron Microscopy and Immunogold Labeling on Tokuyasu Cryosections to Image Influenza A Virus Ribonucleoprotein Transport and Packaging

Multiple hosts and Influenza A viruses genetic mixing

Mutations Conferring Increased Sensitivity to Tripartite Motif 22 Restriction Accumulated Progressively in the Nucleoprotein of Seasonal Influenza A (H1N1) Viruses between 1918 and 2009.

Neuraminidase of 2007-2008 influenza A(H1N1) viruses shows increased affinity for sialic acids due to the D344N substitution

Neuraminidase stalk length and additional glycosylation of the hemagglutinin influence the virulence of influenza H5N1 viruses for mice

Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase

Productive infection of human skeletal muscle cells by pandemic and seasonal influenza A(H1N1) viruses.

Recombinant influenza A viruses harboring optimized dicistronic NA segment with an extended native 5' terminal sequence: induction of heterospecific B and T cell responses in mice

Recruitment of RED-SMU1 complex by Influenza A Virus RNA polymerase to control Viral mRNA splicing

Replication-competent influenza A virus that encodes a split-green fluorescent protein-tagged PB2 polymerase subunit allows live-cell imaging of the virus life cycle

Residue 627 of PB2 is a determinant of cold sensitivity in RNA replication of avian influenza viruses.

Resistance Development to Influenza Virus Sialidase Inhibitors

Sensitivity of H5N1 influenza viruses to oseltamivir: an update

Shortening the unstructured, interdomain region of the non-structural protein NS1 of an avian H1N1 influenza virus increases its replication and pathogenicity in chickens

Structural basis of an essential interaction between influenza polymerase and Pol II CTD.

Synthesis and evaluation of novel 3-C-alkylated-Neu5Ac2en derivatives as probes of influenza virus sialidase 150-loop flexibility

Targeting host calpain proteases decreases influenza A virus infection.

Temperature-Sensitive Mutants in the Influenza A Virus RNA Polymerase: Alterations in the PA Linker Reduce Nuclear Targeting of the PB1-PA Dimer and Result in Viral Attenuation

The RBPome of influenza A virus NP-mRNA reveals a role for TDP-43 in viral replication

The Transcription/Replication Activity of the Polymerase of Influenza A Viruses Is Not Correlated with the Level of Proteolysis Induced by the PA Subunit

The generation of recombinant influenza A viruses expressing a PB2 fusion protein requires the conservation of a packaging signal overlapping the coding and noncoding regions at the 5' end of the PB2 segment

The influenza A virus NS1 protein interacts with the nucleoprotein of viral ribonucleoprotein complexes

The influenza fingerprints: NS1 and M1 proteins contribute to specific host cell ultrastructure signatures upon infection by different influenza A viruses.

Time-Resolved Visualisation of Nearly-Native Influenza A Virus Progeny Ribonucleoproteins and Their Individual Components in Live Infected Cells

Transplantation of adult-derived myoblasts in mice following gene transfer

[Interspecies transmission, adaptation to humans and pathogenicity of animal influenza viruses].