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List of works by Ta-Yuan Chang

A novel cholesterol stain reveals early neuronal cholesterol accumulation in the Niemann-Pick type C1 mouse brain

scientific article

A simple and efficient procedure for the rapid homogenization of cultured animal cells grown in monolayer ⬇️

scientific article published on September 15, 1981

ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD.

scientific article

Acat1 gene ablation in mice increases hematopoietic progenitor cell proliferation in bone marrow and causes leukocytosis.

scientific article published on 11 July 2013

Activation of acyl-coenzyme A:cholesterol acyltransferase activity by cholesterol is not due to altered mRNA levels in HepG2 cells

scientific article published on May 1996

Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid beta-peptide

scientific article

Acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2) is induced in monocyte-derived macrophages: in vivo and in vitro studies

scientific article

Adenovirus expressing an NPC1-GFP fusion gene corrects neuronal and nonneuronal defects associated with Niemann pick type C disease

scientific article published in September 2005

Aspartate carbamyltransferase (Streptococcus faecalis).

scientific article published on January 1978

Binding between the Niemann-Pick C1 protein and a photoactivatable cholesterol analog requires a functional sterol-sensing domain

scholarly article

Biotinylated theta-toxin derivative as a probe to examine intracellular cholesterol-rich domains in normal and Niemann-Pick type C1 cells

scientific article published on February 2003

Cellular pregnenolone esterification by acyl-CoA:cholesterol acyltransferase

scientific article

Chinese hamster ovary cell mutants affecting cholesterol metabolism

scientific article published on April 1997

Cholesterol is superior to 7-ketocholesterol or 7 alpha-hydroxycholesterol as an allosteric activator for acyl-coenzyme A:cholesterol acyltransferase 1

scientific article (publication date: 28 March 2003)

Cloning and characterization of the human megakaryocyte growth and development factor (MGDF) gene

scientific article published in January 1995

Comparison of phosphatidylethanolamine and phosphatidylcholine vesicles produced by treating cholate-phospholipid micelles with cholestyramine

scientific article published on 01 July 1989

Distinct endosomal compartments in early trafficking of low density lipoprotein-derived cholesterol

scientific article published on 28 April 2003

Fate of Endogenously Synthesized Cholesterol in Niemann-Pick Type C1 Cells

scientific article published in Journal of Biological Chemistry

High-efficiency stable gene transfection using chloroquine-treated Chinese hamster ovary cells

scientific article published on September 1991

Human ACAT1 gene expression and its involvement in the development of atherosclerosis

scientific article published on January 2006

Human acyl-CoA:cholesterol acyltransferase 2 gene expression in intestinal Caco-2 cells and in hepatocellular carcinoma.

scientific article

Human acyl-CoA:cholesterol acyltransferase-1 in the endoplasmic reticulum contains seven transmembrane domains

scientific article (publication date: 13 August 1999)

Immunolocalization of Acyl-Coenzyme A:CholesterolO-Acyltransferase in Macrophages

scientific article published in Journal of Biological Chemistry

Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases Aβ1-42 clearance

scientific article

Localization of acyl coenzyme A:cholesterol acyltransferase gene to human chromosome 1q25

scientific article

Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

scientific article

NuMA is a major acceptor of poly(ADP-ribosyl)ation by tankyrase 1 in mitosis.

scientific article

Preparation and characterization of unilamellar vesicles from cholate-phospholipid micelle treated with cholestyramine

scientific article published in September 1986

Promotion of tau phosphorylation by MAP kinase Erk1/2 is accompanied by reduced cholesterol level in detergent-insoluble membrane fraction in Niemann-Pick C1-deficient cells.

scientific article published on March 2003

Purification of Recombinant Acyl-Coenzyme A:Cholesterol Acyltransferase 1 (ACAT1) from H293 Cells and Binding Studies between the Enzyme and Substrates Using Difference Intrinsic Fluorescence Spectroscopy ⬇️

scientific article published on October 29, 2010

Role of Niemann-Pick type C1 protein in intracellular trafficking of low density lipoprotein-derived cholesterol

scientific article published in February 2000

Role of the N-terminal hydrophilic domain of acyl-coenzyme A:cholesterol acyltransferase 1 on the enzyme's quaternary structure and catalytic efficiency

scientific article published in March 2002

Roles of acyl-coenzyme A:cholesterol acyltransferase-1 and -2

scientific article (publication date: June 2001)

Roles of endogenously synthesized sterols in the endocytic pathway

scientific article published on 31 May 2006

Somatic cell genetic analysis of two classes of CHO cell mutants expressing opposite phenotypes in sterol-depedent regulation of cholesterol metabolism

scientific article published in November 1994

Somatic cell genetic and biochemical characterization of cell lines resulting from human genomic DNA transfections of Chinese hamster ovary cell mutants defective in sterol-dependent activation of sterol synthesis and LDL receptor expression

scientific article published on May 1994

TNF-alpha stimulates the ACAT1 expression in differentiating monocytes to promote the CE-laden cell formation

scientific article

The cytosolic adaptor AP-1A is essential for the trafficking and function of Niemann-Pick type C proteins

scientific article published on 20 February 2013

The epigenetic drug 5-azacytidine interferes with cholesterol and lipid metabolism

scientific article

The structure of acyl coenzyme A-cholesterol acyltransferase and its potential relevance to atherosclerosis.

scientific article

Trafficking defects in endogenously synthesized cholesterol in fibroblasts, macrophages, hepatocytes, and glial cells from Niemann-Pick type C1 mice

scientific article

Translocation of both lysosomal LDL-derived cholesterol and plasma membrane cholesterol to the endoplasmic reticulum for esterification may require common cellular factors involved in cholesterol egress from the acidic compartments (lysosomes/endoso

scientific article published on February 1995

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