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List of works by Michael E. Weale

A Bayesian method to incorporate hundreds of functional characteristics with association evidence to improve variant prioritization.

scientific article

A critical evaluation of genomic control methods for genetic association studies

scientific article published on May 2009

A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis

scientific article

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

scientific article

A genome-wide investigation of SNPs and CNVs in schizophrenia

scientific article

A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB

scientific article

A novel polymorphism associated with lactose tolerance in Africa: multiple causes for lactase persistence?

scientific article published on 21 November 2006

A single-nucleotide polymorphism tagging set for human drug metabolism and transport

scientific article published on 19 December 2004

Alternative ion channel splicing in mesial temporal lobe epilepsy and Alzheimer's disease

scientific article published on January 2007

An additional k-means clustering step improves the biological features of WGCNA gene co-expression networks

scientific article

An assessment of the Irish population for large-scale genetic mapping studies involving epilepsy and other complex diseases

Analysis of European case-control studies suggests that common inherited variation in mitochondrial DNA is not involved in susceptibility to amyotrophic lateral sclerosis

scientific article published on 13 March 2012

Armenian Y chromosome haplotypes reveal strong regional structure within a single ethno-national group

scientific article (publication date: December 2001)

Assessing models for genetic prediction of complex traits: a comparison of visualization and quantitative methods

scientific article published on 22 May 2015

Assessment of common variability and expression quantitative trait loci for genome-wide associations for progressive supranuclear palsy

scientific article

Association of Multidrug Resistance in Epilepsy with a Polymorphism in the Drug-Transporter GeneABCB1

article

Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study

scientific article published on October 2010

Common genetic variants in complement genes other than CFH, CD46 and the CFHRs are not associated with aHUS.

scientific article

Common genetic variants influence human subcortical brain structures

scientific article

Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis

scientific article

Correction: A Genome-Wide Investigation of SNPs and CNVs in Schizophrenia

Corrigendum to "Assessment of common variability and expression quantitative trait loci for genome-wide associations for progressive supranuclear palsy." [Neurobiol. Aging 35 (2014) 1514.e1-1514.e12].

scientific article published on 19 October 2015

Delta-centralization fails to control for population stratification in genetic association studies

scientific article

Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A.

scientific article published on 06 September 2013

Evolution of a length polymorphism in the human PER3 gene, a component of the circadian system

scientific article

Fine-mapping, gene expression and splicing analysis of the disease associated LRRK2 locus

scientific article

Founding mothers of Jewish communities: geographically separated Jewish groups were independently founded by very few female ancestors

scientific article

Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis

scientific article

Gene expression changes with age in skin, adipose tissue, blood and brain

scientific article

Genes predict village of origin in rural Europe

scientific article

Genetic and isotopic analysis and the UK Border Agency

Genetic determinants of variable metabolism have little impact on the clinical use of leading antipsychotics in the CATIE study

scientific article published on October 2008

Genetic enhancement of cognition in a kindred with cone-rod dystrophy due to RIMS1 mutation

scientific article

Genetic evidence for a pathogenic role for the vitamin D3 metabolizing enzyme CYP24A1 in multiple sclerosis

scientific article

Genetic intra-tumour heterogeneity in epithelial ovarian cancer and its implications for molecular diagnosis of tumours

scientific article published on 01 February 2007

Genetic signatures reveal high-altitude adaptation in a set of ethiopian populations ⬇️

scientific article

Genetic variability in the regulation of gene expression in ten regions of the human brain

scientific article

Genome scans and candidate gene approaches in the study of common diseases and variable drug responses

article

Genome-scale methods converge on key mitochondrial genes for the survival of human cardiomyocytes in hypoxia

scientific article

Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.

scientific article

Genome-wide association study of major recurrent depression in the U.K. population

scientific article published in June 2010

High-resolution Y chromosome haplotypes of Israeli and Palestinian Arabs reveal geographic substructure and substantial overlap with haplotypes of Jews

scientific article (publication date: December 2000)

High-throughput analysis of informative CYP2D6 compound haplotypes

scientific article published in February 2003

Identification of common variants associated with human hippocampal and intracranial volumes

scientific article published on 15 April 2012

Identifying candidate causal variants responsible for altered activity of the ABCB1 multidrug resistance gene

scientific article published on 14 June 2004

Increased prevalence of M694V in patients with ankylosing spondylitis: additional evidence for a link with familial mediterranean fever

scientific article published on October 2010

Inferring separate parental admixture components in unknown DNA samples using autosomal SNPs

scientific article published on 27 June 2012

Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci

scientific article published on 30 January 2013

Insights into TREM2 biology by network analysis of human brain gene expression data

scientific article

Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain

scientific article

Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis

scientific article published on 10 July 2012

Large-scale pathways-based association study in amyotrophic lateral sclerosis

scientific article

Little genetic differentiation as assessed by uniparental markers in the presence of substantial language variation in peoples of the Cross River region of Nigeria

scientific article

Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study

scientific article published in February 2018

Long-range LD can confound genome scans in admixed populations

scientific article published on July 2008

MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies

scientific article

Multicentre search for genetic susceptibility loci in sporadic epilepsy syndrome and seizure types: a case-control study

scientific article published in November 2007

Multiple origins of Ashkenazi Levites: Y chromosome evidence for both Near Eastern and European ancestries

scientific article

Multiple rare variants as a cause of a common phenotype: several different lactase persistence associated alleles in a single ethnic group

scientific article published on 24 November 2009

Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis

scientific article

Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders

scientific article

Network-Informed Gene Ranking Tackles Genetic Heterogeneity in Exome-Sequencing Studies of Monogenic Disease

scientific article published on 23 September 2015

New genetic evidence supports isolation and drift in the Ladin communities of the South Tyrolean Alps but not an ancient origin in the Middle East

scientific article (publication date: 2008)

No major role of common SV2A variation for predisposition or levetiracetam response in epilepsy.

scientific article published on 31 October 2008

Novel genetic loci associated with hippocampal volume

scientific article published on 18 January 2017

Novel genetic loci underlying human intracranial volume identified through genome-wide association

scientific article (publication date: 3 October 2016)

Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes

scientific article

Population genetic approaches to neurological disease: Parkinson's disease as an example

scientific article

Population genetic structure of variable drug response

scientific article

Population genomics: Linkage disequilibrium holds the key

scientific article published on 01 July 2001

Positive selection on a high-sensitivity allele of the human bitter-taste receptor TAS2R16.

scientific article published in July 2005

Promoter polymorphisms and allelic imbalance in ABCB1 expression

scientific article published in November 2007

Quality control for genome-wide association studies

scientific article published on January 2010

Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies

scientific article

Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies

article

Rare Deep-Rooting Y Chromosome Lineages in Humans: Lessons for Phylogeography ⬇️

scientific article published on September 1, 2003

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease

scientific article

Recursive splicing in long vertebrate genes

scientific article

Reply to 'Haplotype block structure of the cytochrome P450 CYP2C gene cluster on chromosome 10'

article

Resolving the polymorphism-in-probe problem is critical for correct interpretation of expression QTL studies

scientific article published on 21 February 2013

Sex-Specific Genetic Data Support One of Two Alternative Versions of the Foundation of the Ruling Dynasty of the Nso' in Cameroon.

scientific article

Smoking Gun or Circumstantial Evidence? Comparison of Statistical Learning Methods using Functional Annotations for Prioritizing Risk Variants.

scientific article

Systematic assessment of the influence of complement gene polymorphisms on kidney transplant outcome.

scientific article published on 12 December 2015

Tapping into success and collaboration

scientific article published in Nature

The C9ORF72 expansion mutation is a common cause of ALS+/-FTD in Europe and has a single founder

scientific article

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

scientific article

The T allele of a single-nucleotide polymorphism 13.9 kb upstream of the lactase gene (LCT) (C-13.9kbT) does not predict or cause the lactase-persistence phenotype in Africans

scientific article

The influence of density on frequency-dependent selection by wild birds feeding on artificial prey.

scientific article published in June 1998

The potentially deleterious functional variant flavin-containing monooxygenase 2*1 is at high frequency throughout sub-Saharan Africa

scientific article published on October 2008

Transethnic differences in GWAS signals: A simulation study.

scientific article published on 7 May 2018

Using Functional Annotation for the Empirical Determination of Bayes Factors for Genome-Wide Association Study Analysis ⬇️

scientific article (publication date: 27 April 2011)

Widespread sex differences in gene expression and splicing in the adult human brain

scientific article published on January 2013

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