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List of works by Eng Eong Ooi

2505. A Novel Mobile Phone Application for Remote Research Data Collection is Effective in Monitoring Chronic Sequelae After Acute Viral Infections

A Dynamic Immune Response Shapes COVID-19 Progression

scientific article published on 30 April 2020

A Non-structural 1 Protein G53D Substitution Attenuates a Clinically Tested Live Dengue Vaccine

scientific article published on 01 May 2020

A Prospective Clinical Study on the Use of Reverse Transcription-Polymerase Chain Reaction for the Early Diagnosis of Dengue Fever

scientific article (publication date: November 2006)

A Report of Adult Human Adenovirus Infections in a Tertiary Hospital

scientific article

A T164S mutation in the dengue virus NS1 protein is associated with greater disease severity in mice

scientific article published on 01 June 2019

A TLR3 ligand that exhibits potent inhibition of influenza virus replication and has strong adjuvant activity has the potential for dual applications in an influenza pandemic.

scientific article

A human PrM antibody that recognizes a novel cryptic epitope on dengue E glycoprotein

scientific article

A label-free immunosensor for diagnosis of Dengue infection with simple electrical measurements

scientific article published on 7 October 2009

A method for full genome sequencing of all four serotypes of the dengue virus

scientific article published on 30 June 2010

A simple and powerful method for the estimation of intervention effects on serological endpoints using paired interval-censored data

scientific article

A simple method for Alexa Fluor dye labelling of dengue virus

scientific article published on 23 April 2010

A systematic approach to the development of a safe live attenuated Zika vaccine.

scientific article published on 12 March 2018

Acinetobacter calcoaceticus–Acinetobacter baumannii complex species in clinical specimens in Singapore

article

Acquired carbapenemases in Enterobactericeae in Singapore, 1996-2012

scientific article published on 01 October 2013

Activation of the innate immune system provides broad-spectrum protection against influenza A viruses with pandemic potential in mice

scientific article

An adjuvant for the induction of potent, protective humoral responses to an H5N1 influenza virus vaccine with antigen-sparing effect in mice

scientific article

An outbreak of primary dengue infection among migrant Chinese workers in Singapore characterized by prominent gastrointestinal symptoms and a high proportion of symptomatic cases

scientific article

Analysis of Dengue Virus Genetic Diversity during Human and Mosquito Infection Reveals Genetic Constraints

scientific article

Antibiotic susceptibility of 50 clinical isolates of Burkholderia pseudomallei from Singapore

scientific article published on 02 September 2006

Antibody-Dependent Dengue Virus Entry Modulates Cell Intrinsic Responses for Enhanced Infection

scientific article published on 18 September 2019

Antimicrobial activity of cathelicidin peptides against Burkholderia pseudomallei, the causative agent of melioidosis

Application of a targeted-enrichment methodology for full-genome sequencing of Dengue 1-4, Chikungunya and Zika viruses directly from patient samples

scientific article published on 25 April 2019

Assessing the epidemiological effect of wolbachia for dengue control

scientific article

Association between microsatellites within the human MHC and nasopharyngeal carcinoma

scientific article published on 01 April 1997

Asymptomatic SARS-CoV-2 infection

scientific article published on 12 June 2020

Asymptomatic dengue infection may trigger Guillain-Barré syndrome

scientific article published on 26 September 2016

Attenuated dengue viruses are genetically more diverse than their respective wild-type parents

scientific article published on 20 May 2021

Augmentation of 5-lipoxygenase activity and expression during dengue serotype-2 infection

scientific article published on 30 October 2013

Burkholderia pseudomallei aerosol infection results in differential inflammatory responses in BALB/c and C57Bl/6 mice

article

Celgosivir treatment misfolds dengue virus NS1 protein, induces cellular pro-survival genes and protects against lethal challenge mouse model

scientific article

Cell surface α2,3-linked sialic acid facilitates Zika virus internalization

scientific article published on 01 January 2019

Challenges in prevaccination screening for previous dengue infection

scientific article published on 01 January 2021

Characteristics of acute febrile illness and determinants of illness recovery among adults presenting to Singapore primary care clinics

scientific article

Characterization of early host responses in adults with dengue disease

scientific article

Chikungunya and dengue fever among hospitalized febrile patients in northern Tanzania

scientific article published on January 2012

Chikungunya in Singapore: imported cases among travelers visiting friends and relatives

scientific article published in July 2009

Chloroquine for influenza prevention: a randomised, double-blind, placebo controlled trial

scientific article

Chymase is a Predictive Biomarker of Dengue Hemorrhagic Fever in Pediatric and Adult Patients

scientific article published on 25 August 2017

Contribution of herpesvirus specific CD8 T cells to anti-viral T cell response in humans.

scientific article

Cost-Effective Real-Time Reverse Transcriptase PCR (RT-PCR) To Screen for Dengue Virus followed by Rapid Single-Tube Multiplex RT-PCR for Serotyping of the Virus

scientific article (publication date: March 2007)

Cross-Reactivity and Anti-viral Function of Dengue Capsid and NS3-Specific Memory T Cells Toward Zika Virus

scientific article published on 01 October 2018

Cross-reactive antibodies enhance live attenuated virus infection for increased immunogenicity.

scientific article published on 19 September 2016

Current Status of Dengue Therapeutics Research and Development

scientific article

Decision Tree Algorithms Predict the Diagnosis and Outcome of Dengue Fever in the Early Phase of Illness

scientific article

Dengue

scientific article published on 01 January 2019

Dengue Disease Modelling and Forecasting: Utility and Limitations

scientific article published in April 2016

Dengue E Protein Domain III-Based DNA Immunisation Induces Strong Antibody Responses to All Four Viral Serotypes

scientific article (publication date: 2015)

Dengue Mosaic Vaccines Enhance Cellular Immunity and Expand the Breadth of Neutralizing Antibody Against All Four Serotypes of Dengue Viruses in Mice

scientific article published on 20 June 2019

Dengue Virus-Infected Dendritic Cells, but Not Monocytes, Activate Natural Killer Cells through a Contact-Dependent Mechanism Involving Adhesion Molecules

scientific article published on August 2017

Dengue and Dengue Hemorrhagic Fever

Dengue pre-vaccination serology screening for the use of Dengvaxia®

scientific article published on 01 December 2019

Dengue seroepidemiology in Singapore

scientific article published in The Lancet

Dengue subgenomic RNA binds TRIM25 to inhibit interferon expression for epidemiological fitness

scientific article published on 2 July 2015

Dengue subgenomic flaviviral RNA disrupts immunity in mosquito salivary glands to increase virus transmission

scientific article published on 28 July 2017

Dengue vaccine-induced CD8+ T cell immunity confers protection in the context of enhancing, interfering maternal antibodies

scientific article published on 21 December 2017

Dengue virus activates cGAS through the release of mitochondrial DNA

scientific article

Dengue virus activates polyreactive, natural IgG B cells after primary and secondary infection

scientific article

Dengue virus compartmentalization during antibody-enhanced infection

scientific article

Dengue virus growth, purification, and fluorescent labeling

scientific article published on January 2014

Dengue virus induces PCSK9 expression to alter antiviral responses and disease outcomes

scientific article published on 09 July 2020

Dengue virus neutralization in cells expressing Fc gamma receptors

scientific article

Dengue--old disease, new challenges in an ageing population.

scientific article published in August 2013

Dengue: an update on treatment options

scientific article

Development of a Western blot assay for detection of antibodies against coronavirus causing severe acute respiratory syndrome

scientific article published on March 2004

Development of a simplified assay for the detection of neutralizing antibodies to Japanese encephalitis virus

scientific article published on April 2001

Development of real-time PCR assays and evaluation of their potential use for rapid detection of Burkholderia pseudomallei in clinical blood specimens

scientific article

Diagnosis of dengue: an update

scientific article published on August 2012

Discovery and Validation of Prognostic Biomarker Models to Guide Triage among Adult Dengue Patients at Early Infection

scientific article

Disentangling etiologies of CNS infections in Singapore using multiple correspondence analysis and random forest

scientific article published on 26 October 2020

Distribution of Aedes mosquitoes in the Kilimanjaro Region of northern Tanzania

scientific article published on May 2016

Dose- and schedule-dependent protective efficacy of celgosivir in a lethal mouse model for dengue virus infection informs dosing regimen for a proof of concept clinical trial.

scientific article published on 31 July 2012

Early events of SARS coronavirus infection in vero cells

scientific article published in November 2003

Early molecular correlates of adverse events following yellow fever vaccination

scientific article published on 5 October 2017

Economic analysis of pandemic influenza vaccination strategies in Singapore.

scientific article

Economic impact of dengue illness and the cost-effectiveness of future vaccination programs in Singapore

scientific article

Effect of increasing age on the trend of dengue and dengue hemorrhagic fever in Singapore

scientific article published on 01 September 2003

Efficacy and safety of celgosivir in patients with dengue fever (CELADEN): a phase 1b, randomised, double-blind, placebo-controlled, proof-of-concept trial

scientific article

Emergence potential of sylvatic dengue virus type 4 in the urban transmission cycle is restrained by vaccination and homotypic immunity

scientific article published on 26 February 2013

Epidemiology, Outcomes and Prognosis of Central Nervous System Infections in Singapore. Preliminary results from The Singapore Neurologic Infections Programme (SNIP).

scientific article published on 4 October 2017

Epitope characterization of the protective monoclonal antibody VN04-2 shows broadly neutralizing activity against highly pathogenic H5N1.

scientific article

Erratum: Author Correction: Mimicking immune signatures of flavivirus infection with targeted adjuvants improves dengue subunit vaccine immunogenicity

scientific article published on 24 October 2019

Etiology of severe non-malaria febrile illness in Northern Tanzania: a prospective cohort study

scientific article

Evaluation of the NS1 Rapid Test and the WHO Dengue Classification Schemes for Use as Bedside Diagnosis of Acute Dengue Fever in Adults ⬇️

scientific article published on February 1, 2011

Evolution of Subgenomic RNA Shapes Dengue Virus Adaptation and Epidemiological Fitness

scientific article published on 28 June 2019

Evolution of subgenomic RNA shapes dengue virus adaptation and epidemiological fitness

scholarly article published 19 February 2018

Extended Evaluation of Virological, Immunological and Pharmacokinetic Endpoints of CELADEN: A Randomized, Placebo-Controlled Trial of Celgosivir in Dengue Fever Patients

scientific article

Fc receptors and their influence on efficacy of therapeutic antibodies for treatment of viral diseases

scientific article

First experimental in vivo model of enhanced dengue disease severity through maternally acquired heterotypic dengue antibodies

scientific article

Flavivirus serocomplex cross-reactive immunity is protective by activating heterologous memory CD4 T cells.

scientific article published on 4 July 2018

Gene Microarray Analyses of Daboia russelli russelli Daboiatoxin Treatment of THP-1 Human Macrophages Infected with Burkholderia pseudomallei.

scientific article published on 22 November 2015

Genetic diversity of respiratory enteroviruses and rhinoviruses in febrile adults, Singapore, 2007-2013

scientific article published on 30 September 2019

Genomic Epidemiology of a Dengue Virus Epidemic in Urban Singapore

scientific article

Genomic signature of early T-cell response is associated with lower antibody titer threshold for sterilizing immunity

scientific article published on 30 March 2019

Higher risk of infection with dengue at the weekend among male Singaporeans

scientific article

Host cell transcriptome profile during wild-type and attenuated dengue virus infection

scientific article

Hypertonic saline reduces vascular leakage in a mouse model of severe dengue

scientific article

Hypoxia enhances antibody-dependent dengue virus infection

scientific article

Identification and characterization of host proteins bound to dengue virus 3' UTR reveal an antiviral role for quaking proteins.

scientific article

Immune modulation in COVID-19: Strategic considerations for personalized therapeutic intervention

scientific article published on 01 July 2020

Immunological characterization of the spike protein of the severe acute respiratory syndrome coronavirus

scientific article published on April 2004

Impact of immune enhancement on Covid-19 polyclonal hyperimmune globulin therapy and vaccine development

scientific article published on 16 April 2020

In vitro inhibition of human influenza A virus replication by chloroquine

scientific article

Induction of Human T-cell and Cytokine Responses Following Vaccination with a Novel Influenza Vaccine

scientific article published in Scientific Reports

Influenza B outbreak among influenza-vaccinated welfare home residents in Singapore.

scientific article published on June 2010

Inhibition of SARS coronavirus infection in vitro with clinically approved antiviral drugs

scientific article published in April 2004

Inhibition of megakaryocyte development in the bone marrow underlies dengue virus-induced thrombocytopenia in humanized mice

scientific article

Innate immune responses of pulmonary epithelial cells to Burkholderia pseudomallei infection

scientific article

Japanese encephalitis, Singapore.

scientific article published on March 2006

Lack of association of dengue activity with haze.

scientific article

Leukocyte immunoglobulin-like receptor B1 is critical for antibody-dependent dengue

scientific article published on 13 January 2014

Ligation of Fc gamma receptor IIB inhibits antibody-dependent enhancement of dengue virus infection

scientific article

Live vaccine infection burden elicits adaptive humoral and cellular immunity required to prevent Zika virus infection

scientific article published on 08 October 2020

Localised outbreak of Falciparum malaria in Singapore.

scientific article published in July 2003

Metabolic perturbations and cellular stress underpin susceptibility to symptomatic live-attenuated yellow fever infection

scientific article published on 15 July 2019

Microarray and real-time RT-PCR analyses of differential human gene expression patterns induced by severe acute respiratory syndrome (SARS) coronavirus infection of Vero cells

scientific article published on 22 January 2005

Microneedle‐based intradermal delivery of stabilized dengue virus.

scientific article

Microvesicles from malaria-infected red blood cells activate natural killer cells via MDA5 pathway

scientific article published on 04 October 2018

Mild illness associated with severe acute respiratory syndrome coronavirus infection: lessons from a prospective seroepidemiologic study of health-care workers in a teaching hospital in Singapore

scientific article published on 30 January 2004

Mimicking immune signatures of flavivirus infection with targeted adjuvants improves dengue subunit vaccine immunogenicity

scientific article published on 25 June 2019

Molecular analysis of serum and bronchoalveolar lavage in a mouse model of influenza reveals markers of disease severity that can be clinically useful in humans

scientific article

Molecular biomarkers at the interface of basic and clinical dengue research

scientific article published on November 2013

Molecular determinants of plaque size as an indicator of dengue virus attenuation

scientific article published on 17 May 2016

Monkey malaria in humans: a diagnostic dilemma with conflicting laboratory data.

scientific article

Multilocus sequence types of carbapenem-resistant Pseudomonas aeruginosa in Singapore carrying metallo-beta-lactamase genes, including the novel bla(IMP-26) gene

scientific article

Mutational dynamics of the SARS coronavirus in cell culture and human populations isolated in 2003

scientific article

Naturally acquired human Plasmodium knowlesi infection, Singapore

scientific article

Neuroimmunomodulation: Neuroendocrine Regulation of Immunity: The Effects of Noradrenaline inXenopus Laevis, the South African Clawed Toad

scholarly article by Richard H. Clothier et al published January 1991 in International Journal of Neuroscience

Neutralization of antibody-enhanced dengue infection by VIS513, a pan serotype reactive monoclonal antibody targeting domain III of the dengue E protein

scientific article published on 9 February 2018

Neutralization of dengue virus in the presence of Fc receptor-mediated phagocytosis distinguishes serotype-specific from cross-neutralizing antibodies

scientific article

Neutralizing human monoclonal antibody against H5N1 influenza HA selected from a Fab-phage display library.

scientific article

New dengue virus type 1 genotype in Colombo, Sri Lanka

scientific article published in November 2011

Novel immunofluorescence assay using recombinant nucleocapsid-spike fusion protein as antigen to detect antibodies against severe acute respiratory syndrome coronavirus

scientific article

Optimizing celgosivir therapy in mouse models of dengue virus infection of serotypes 1 and 2: The search for a window for potential therapeutic efficacy

scientific article published on 12 January 2016

Oxygen: viral friend or foe?

scientific article published on 27 July 2020

Passive immunoprophylaxis and therapy with humanized monoclonal antibody specific for influenza A H5 hemagglutinin in mice

scientific article

Patient-based transcriptome-wide analysis identify interferon and ubiquination pathways as potential predictors of influenza A disease severity

scientific article

Patterns of medication use and factors associated with antibiotic use among adult fever patients at Singapore primary care clinics.

scientific article

Peridomestic Aedes malayensis and Aedes albopictus are capable vectors of arboviruses in cities

scientific article

Persistent Dengue Infection in an Immunosuppressed Patient Reveals the Roles of Humoral and Cellular Immune Responses in Virus Clearance

scientific article published on 29 October 2019

Phase 1 Trial of a Therapeutic Anti-Yellow Fever Virus Human Antibody

scientific article published on 01 July 2020

Positive epistasis between viral polymerase and the 3' untranslated region of its genome reveals the epidemiologic fitness of dengue virus

scientific article published on 04 May 2020

Pre- and post-exposure prophylaxis of experimental Burkholderia pseudomallei infection with doxycycline, amoxicillin/clavulanic acid and co-trimoxazole

scientific article

Preclinical evaluation of VIS513, a therapeutic antibody against dengue virus, in non-human primates

scientific article published on 18 May 2017

Preparing for introduction of a dengue vaccine: recommendations from the 1st Dengue v2V Asia-Pacific Meeting

scientific article published on 22 August 2011

Presence of hemagglutination inhibition and neutralization antibodies to Japanese encephalitis virus in wild pigs on an offshore island in Singapore

scientific article published in March 2002

Preventing Dengue Epidemics during the COVID-19 Pandemic

scientific article published on 15 June 2020

Production of Infectious Dengue Virus in Aedes aegypti Is Dependent on the Ubiquitin Proteasome Pathway

scientific article (publication date: November 2015)

Profiles of antibody responses against severe acute respiratory syndrome coronavirus recombinant proteins and their potential use as diagnostic markers

scientific article published on March 2004

Prognosticating Dengue

scientific article published on 28 December 2016

Proliferative growth of SARS coronavirus in Vero E6 cells

scientific article published on 01 December 2003

Proteasome Inhibition Suppresses Dengue Virus Egress in Antibody Dependent Infection

scientific article

Rapid molecular typing of Burkholderia pseudomallei, isolated in an outbreak of melioidosis in Singapore in 2004, based on variable-number tandem repeats

scientific article

Rational Engineering and Characterization of an mAb that Neutralizes Zika Virus by Targeting a Mutationally Constrained Quaternary Epitope.

scientific article

Re: Dengue fever outbreak: prevention possible (author's reply).

scientific article published in September 2013

Reconstructing historical changes in the force of infection of dengue fever in Singapore: implications for surveillance and control

scientific article published on March 2008

Regarding "Dengue--How Best to Classify It"

scientific article published on 2 April 2012

Reply to "Use of Prediction Models for Risk Analysis and Decision-Making in Public Health-The Catch-22 Conundrum".

scientific article published on August 2016

Repurposing Ivermectin as an Anti-dengue Drug

scientific article published on 28 October 2020

Review article: Research on dengue during World War II revisited

scientific article

SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls

scientific article published on 15 July 2020

Safety and immunogenicity of a virus-like particle pandemic influenza A (H1N1) 2009 vaccine: results from a double-blinded, randomized Phase I clinical trial in healthy Asian volunteers.

scientific article

Scrub typhus with sepsis and acute respiratory distress syndrome

scientific article published on 12 June 2013

Sequential immunization induces strong and broad immunity against all four dengue virus serotypes

scientific article published on 24 July 2020

Serial Metabolome Changes in a Prospective Cohort of Subjects with Influenza Viral Infection and Comparison with Dengue Fever.

scientific article published on 31 May 2017

Seroepidemiology of neutralizing antibodies to Japanese encephalitis virus in Singapore: continued transmission despite abolishment of pig farming?

scientific article published on November 2004

Serological response to trivalent inactivated influenza vaccine in HIV-infected adults in Singapore

scientific article published on 17 February 2017

Serum Metabolomics Investigation of Humanized Mouse Model of Dengue Virus Infection

scientific article

Serum Metabolomics Reveals Serotonin as a Predictor of Severe Dengue in the Early Phase of Dengue Fever

scientific article

Serum metabolome and lipidome changes in adult patients with primary dengue infection.

scientific article

Serum metabolome changes in adult patients with severe dengue in the critical and recovery phases of dengue infection

scientific article published on 24 January 2018

Serum proteome and cytokine analysis in a longitudinal cohort of adults with primary dengue infection reveals predictive markers of DHF.

scientific article

South-Asian tsunami

scientific article

Structural and biological diversity of lipopolysaccharides from Burkholderia pseudomallei and Burkholderia thailandensis

scientific article published on 19 August 2009

Structure mapping of dengue and Zika viruses reveals functional long-range interactions

scientific article published on 29 March 2019

Structure mapping of dengue and Zika viruses reveals new functional long-range interactions

scholarly article published 1 August 2018

Structure-Guided Design of an Anti-dengue Antibody Directed to a Non-immunodominant Epitope

scientific article

Successful clearance of human parainfluenza virus type 2 viraemia with intravenous ribavirin and immunoglobulin in a patient with acute myocarditis

scientific article published on 6 November 2012

Sulfated polysaccharide, curdlan sulfate, efficiently prevents entry/fusion and restricts antibody-dependent enhancement of dengue virus infection in vitro: a possible candidate for clinical application

scientific article

Surveillance, prevention, and control of legionellosis in a tropical city-state

scientific article published on June 2005

The 2007 dengue outbreak in Singapore

scientific article published on 10 February 2010

The 5' and 3' Untranslated Regions of the Flaviviral Genome

scientific article

The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production

scientific article

The C-terminal 50 amino acid residues of dengue NS3 protein are important for NS3-NS5 interaction and viral replication

scientific article

The Lancet Commission on dengue and other Aedes-transmitted viral diseases

scientific article published on 01 June 2020

The combination of type I IFN, TNF-α, and cell surface receptor engagement with dendritic cells enables NK cells to overcome immune evasion by dengue virus

scientific article published on 15 October 2014

The core and accessory genomes of Burkholderia pseudomallei: implications for human melioidosis

scientific article published in October 2008

The early clinical features of dengue in adults: challenges for early clinical diagnosis

scientific article

The effects of aging on host resistance and disease tolerance to SARS-CoV-2 infection

scientific article published on 30 October 2020

The performance of RT-PCR compared with a rapid serological assay for acute dengue fever in a diagnostic laboratory

scientific article

The rapid identification of Clostridium perfringens as the possible aetiology of a diarrhoeal outbreak using PCR

article

The re-emergence of dengue in China

scientific article

The role of pre-existing cross-reactive antibodies in determining the efficacy of vaccination in humans: study protocol for a randomized controlled trial

scientific article

The structural basis for serotype-specific neutralization of dengue virus by a human antibody

scientific article

The use of antibodies in the treatment of infectious diseases.

scientific article published on July 2009

The α-dystroglycan N-terminus is a broad-spectrum antiviral agent against SARS-CoV-2 and enveloped viruses

scientific article published in 2024

Therapeutic antibodies as a treatment option for dengue fever

scientific article published on 04 October 2013

Tissue-specific expansion of Zika virus isogenic variants drive disease pathogenesis

scientific article published in 2023

Tuberculous meningitis is a major cause of mortality and morbidity in adults with central nervous system infections in Kota Kinabalu, Sabah, Malaysia: an observational study

scientific article

Unfolded protein response (UPR) gene expression during antibody-dependent enhanced infection of cultured monocytes correlates with dengue disease severity

scientific article published on June 2011

Usefulness and applicability of the revised dengue case classification by disease: multi-centre study in 18 countries

scientific article

Viral Manipulation of Host Inhibitory Receptor Signaling for Immune Evasion

scientific article

Visualizing dengue virus through Alexa Fluor labeling

scientific article

When Can One Vaccinate with a Live Vaccine after Wild-Type Dengue Infection?

scientific article published on 09 April 2020

bla(OXA-181)-positive Klebsiella pneumoniae, Singapore

scientific article published on September 2012

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