List of works - Wiljan Hendriks

A closed binding pocket and global destabilization modify the binding properties of an alternatively spliced form of the second PDZ domain of PTP-BL

scientific article

A decrease in size and number of basal forebrain cholinergic neurons is paralleled by diminished hippocampal cholinergic innervation in mice lacking leukocyte common antigen-related protein tyrosine phosphatase activity

scientific article

A novel strategy for the development of selective active-site inhibitors of the protein tyrosine phosphatase-like proteins islet-cell antigen 512 (IA-2) and phogrin (IA-2beta).

scientific article published on July 2003

A null mutation in the cystatin M/E gene of ichq mice causes juvenile lethality and defects in epidermal cornification

scientific journal article

Altered MAP kinase phosphorylation and impaired motor coordination in PTPRR deficient mice

scientific article

Alu B2 type repeats in the alpha A crystallin locus in the mole rat (Spalax ehrenbergi) genome

scientific article

An animal model for Norrie disease (ND): gene targeting of the mouse ND gene

scientific article published in January 1996

Analysis of protein-protein interaction between late cornified envelope proteins and corneodesmosin

scientific article published on 01 October 2014

Assignment of Ptprn2, the gene encoding receptor-type protein tyrosine phosphatase IA-2beta, a major autoantigen in insulin-dependent diabetes mellitus, to mouse chromosome region 12F.

scientific article

Assignment of the human gene for receptor-type protein tyrosine phosphatase IA-2 (PTPRN) to chromosome region 2q35 --> q36.1 and identification of an intragenic genetic marker

scientific article

Assignment1 of the PTP-SL/PTPBR7 gene (Ptprr/PTPRR) to mouse chromosome region 8A2 by in situ hybridization

scientific article (publication date: 1999)

Cathepsin B as a potential cystatin M/E target in the mouse hair follicle.

scientific article published on 08 June 2017

Certainty-based marking in a formative assessment improves student course appreciation but not summative examination scores

scientific article published on 31 May 2019

Characterization of multiple transcripts and isoforms derived from the mouse protein tyrosine phosphatase gene Ptprr

scientific article published in October 2004

Characterization of the myotonic dystrophy region predicts multiple protein isoform-encoding mRNAs

scientific article published on July 1, 1992

Cloning and characterization of mCRIP2, a mouse LIM-only protein that interacts with PDZ domain IV of PTP-BL

scientific journal article

Colocalisation of the protein tyrosine phosphatases PTP-SL and PTPBR7 with beta4-adaptin in neuronal cells

scientific article

Complete structure of the hamster alpha A crystallin gene. Reflection of an evolutionary history by means of exon shuffling

scientific article published in September 1985

Comprehensive protein tyrosine phosphatase mRNA profiling identifies new regulators in the progression of glioma

scientific article published on September 2016

Delayed peripheral nerve regeneration and central nervous system collateral sprouting in leucocyte common antigen-related protein tyrosine phosphatase-deficient mice

scientific article published on March 2003

Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse

scientific article published on September 1998

Downregulation of protein tyrosine phosphatase PTP-BL represses adipogenesis

scientific article published on 9 April 2009

Duck lactate dehydrogenase B/epsilon-crystallin gene. Lens recruitment of a GC-promoter

scientific article published in February 1993

Duck lens epsilon-crystallin and lactate dehydrogenase B4 are identical: a single-copy gene product with two distinct functions.

scientific article

Effects of LAR and PTP-BL phosphatase deficiency on adult mouse retinal cells activated by lens injury

scientific article published in May 2005

Effects of dual targeting of tumor cells and stroma in human glioblastoma xenografts with a tyrosine kinase inhibitor against c-MET and VEGFR2

scientific article

ErbB2, EphrinB1, Src kinase and PTPN13 signaling complex regulates MAP kinase signaling in human cancers

scientific article

Evolution of eye lens crystallins: the stress connection

scientific article

Gene duplication and conversion events shaped three homologous, differentially expressed myosin regulatory light chain (MLC2) genes

scientific article published on 15 March 2012

Genetic variability of the murine creatine kinase B gene locus and related pseudogenes in different inbred strains of mice

scientific article

Identification and molecular characterization of BP75, a novel bromodomain-containing protein

scientific journal article

Identification and sequence analysis of two new members of the SKALP/elafin and SPAI-2 gene family. Biochemical properties of the transglutaminase substrate motif and suggestions for a new nomenclature.

scientific article published in August 1997

Identification and typing of members of the protein-tyrosine phosphatase gene family expressed in mouse brain

scientific article published in September 1992

Identification of a novel MET mutation in high-grade glioma resulting in an auto-active intracellular protein

scientific article published on 11 April 2015

Identification of a novel inactivating mutation in Isocitrate Dehydrogenase 1 (IDH1-R314C) in a high grade astrocytoma.

scientific article published on 27 July 2016

Immune response in mice that lack the interferon-gamma receptor

scientific article published on 19 March 1993

Impaired PTPN13 phosphatase activity in spontaneous or HPV-induced squamous cell carcinomas potentiates oncogene signaling through the MAP kinase pathway

scientific article

Impaired mammary gland development and function in mice lacking LAR receptor-like tyrosine phosphatase activity

scientific article published in August 1997

Inactivation of LAR family phosphatase genes Ptprs and Ptprf causes craniofacial malformations resembling Pierre-Robin sequence

scientific article published on 17 July 2013

Isocitrate dehydrogenase 1-mutated human gliomas depend on lactate and glutamate to alleviate metabolic stress

scientific article published on 12 July 2018

Late cornified envelope (LCE) proteins: distinct expression patterns of LCE2 and LCE3 members suggest nonredundant roles in human epidermis and other epithelia

scientific article published on 03 January 2016

Maturation of ureter-bladder connection in mice is controlled by LAR family receptor protein tyrosine phosphatases

scientific article

Mice lacking leukocyte common antigen-related (LAR) protein tyrosine phosphatase domains demonstrate spatial learning impairment in the two-trial water maze and hyperactivity in multiple behavioural tests

scientific article

Mild impairment of motor nerve repair in mice lacking PTP-BL tyrosine phosphatase activity

scientific article

Molecular cloning of a mouse epithelial protein-tyrosine phosphatase with similarities to submembranous proteins

scientific article published on December 1995

Mouse choroideremia gene mutation causes photoreceptor cell degeneration and is not transmitted through the female germline.

scientific article published in June 1997

Multimerisation of receptor-type protein tyrosine phosphatases PTPBR7 and PTP-SL attenuates enzymatic activity

scientific article published on 17 November 2007

Multimerization of the protein-tyrosine phosphatase (PTP)-like insulin-dependent diabetes mellitus autoantigens IA-2 and IA-2beta with receptor PTPs (RPTPs). Inhibition of RPTPalpha enzymatic activity

scientific article (publication date: 13 December 2002)

No evidence for involvement of mouse protein-tyrosine phosphatase-BAS-like Fas-associated phosphatase-1 in Fas-mediated apoptosis

scientific article

One-Tube-Only Standardized Site-Directed Mutagenesis: An Alternative Approach to Generate Amino Acid Substitution Collections

scientific article

PDZ domains-glue and guide.

scientific article

PTEN-PDZ domain interactions: binding of PTEN to PDZ domains of PTPN13.

scientific article

PTPs emerge as PIPs: protein tyrosine phosphatases with lipid-phosphatase activities in human disease ⬇️

scientific article published on July 29, 2013

Phosphorylation target site specificity for AGC kinases DMPK E and Lats2.

scientific article

Protein Tyrosine Phosphatase PTPRS Is an Inhibitory Receptor on Human and Murine Plasmacytoid Dendritic Cells

scientific journal article

Protein tyrosine phosphatase receptor type R deficient mice exhibit increased exploration in a new environment and impaired novel object recognition memory

scientific article published on 18 February 2014

Protein tyrosine phosphatase receptor type R is required for Purkinje cell responsiveness in cerebellar long-term depression

scientific article

Protein tyrosine phosphatase variants in human hereditary disorders and disease susceptibilities ⬇️

scientific article published on May 23, 2013

Protein tyrosine phosphatases in glioma biology

scientific article published on 21 November 2009

Protein tyrosine phosphatases in health and disease ⬇️

scientific article published on October 1, 2012

Protein tyrosine phosphatases: functional inferences from mouse models and human diseases.

scientific article published on March 2008

Protein tyrosine phosphatases: sequences and beyond

scientific article

Protein-tyrosine phosphatases expressed in mouse epidermal keratinocytes.

scientific article published on May 1996

Proteinaceous Regulators and Inhibitors of Protein Tyrosine Phosphatases.

scientific article published on 12 February 2018

Proteolytic processing of the receptor-type protein tyrosine phosphatase PTPBR7.

scientific article published on 27 November 2006

Psoriasis-Associated Late Cornified Envelope (LCE) Proteins Have Antibacterial Activity.

scientific article published on 17 June 2017

Rapid assessment of protein-tyrosine phosphatase expression levels by RT-PCR with degenerate primers

scientific article

Receptor-like protein tyrosine phosphatases: alike and yet so different

scientific article published on November 1997

Redox-regulated affinity of the third PDZ domain in the phosphotyrosine phosphatase PTP-BL for cysteine-containing target peptides.

scientific article published in July 2005

Stimulated regeneration of the crushed adult rat optic nerve correlates with attenuated expression of the protein tyrosine phosphatases RPTPalpha, STEP, and LAR.

scientific article published in December 2004

Subcellular localization and differentiation-induced redistribution of the protein tyrosine phosphatase PTP-BL in Neuroblastoma cells.

scientific article published on December 2005

Tailor-Made Protein Tyrosine Phosphatases: In Vitro Site-Directed Mutagenesis of PTEN and PTPRZ-B.

scientific article published in January 2016

Targeted disruption of the IA-2beta gene causes glucose intolerance and impairs insulin secretion but does not prevent the development of diabetes in NOD mice.

scientific article

The LAR protein tyrosine phosphatase enables PDGF β-receptor activation through attenuation of the c-Abl kinase activity

scientific article published on 12 February 2011

The alternative splicing product alpha Ains-crystallin is structurally equivalent to alpha A and alpha B subunits in the rat alpha-crystallin aggregate

scientific article published in January 1990

The cystatin M/E-cathepsin L balance is essential for tissue homeostasis in epidermis, hair follicles, and cornea.

scientific article published on 21 May 2010

The gene (PTPN13) encoding the protein tyrosine phosphatase PTP-BL/PTP-BAS is located in mouse chromosome region 5E/F and human chromosome region 4q21

scientific article published on 01 January 1996

The mouse Ptprr gene encodes two protein tyrosine phosphatases, PTP-SL and PTPBR7, that display distinct patterns of expression during neural development.

scientific article published in November 1999

The mouse gene Ptprf encoding the leukocyte common antigen-related molecule LAR: cloning, characterization, and chromosomal localization

scientific journal article

The neuronal nitric oxide synthase PDZ motif binds to -G(D,E)XV* carboxyterminal sequences.

scientific article

The structure of the vimentin gene

scientific article published in November 1983

The zyxin-related protein TRIP6 interacts with PDZ motifs in the adaptor protein RIL and the protein tyrosine phosphatase PTP-BL

scientific article

Tyrosine-specific MAPK phosphatases and the control of ERK signaling in PC12 cells

scientific article published on 29 November 2006

Valosin containing protein (VCP/p97) is a novel substrate for the protein tyrosine phosphatase PTPL1.

scientific article published on 24 September 2012

List of works by Wiljan Hendriks

A closed binding pocket and global destabilization modify the binding properties of an alternatively spliced form of the second PDZ domain of PTP-BL

A decrease in size and number of basal forebrain cholinergic neurons is paralleled by diminished hippocampal cholinergic innervation in mice lacking leukocyte common antigen-related protein tyrosine phosphatase activity

A novel strategy for the development of selective active-site inhibitors of the protein tyrosine phosphatase-like proteins islet-cell antigen 512 (IA-2) and phogrin (IA-2beta).

A null mutation in the cystatin M/E gene of ichq mice causes juvenile lethality and defects in epidermal cornification

Altered MAP kinase phosphorylation and impaired motor coordination in PTPRR deficient mice

Alu B2 type repeats in the alpha A crystallin locus in the mole rat (Spalax ehrenbergi) genome

An animal model for Norrie disease (ND): gene targeting of the mouse ND gene

Analysis of protein-protein interaction between late cornified envelope proteins and corneodesmosin

Assignment of Ptprn2, the gene encoding receptor-type protein tyrosine phosphatase IA-2beta, a major autoantigen in insulin-dependent diabetes mellitus, to mouse chromosome region 12F.

Assignment of the human gene for receptor-type protein tyrosine phosphatase IA-2 (PTPRN) to chromosome region 2q35 --> q36.1 and identification of an intragenic genetic marker

Assignment1 of the PTP-SL/PTPBR7 gene (Ptprr/PTPRR) to mouse chromosome region 8A2 by in situ hybridization

Cathepsin B as a potential cystatin M/E target in the mouse hair follicle.

Certainty-based marking in a formative assessment improves student course appreciation but not summative examination scores

Characterization of multiple transcripts and isoforms derived from the mouse protein tyrosine phosphatase gene Ptprr

Characterization of the myotonic dystrophy region predicts multiple protein isoform-encoding mRNAs

Cloning and characterization of mCRIP2, a mouse LIM-only protein that interacts with PDZ domain IV of PTP-BL

Colocalisation of the protein tyrosine phosphatases PTP-SL and PTPBR7 with beta4-adaptin in neuronal cells

Complete structure of the hamster alpha A crystallin gene. Reflection of an evolutionary history by means of exon shuffling

Comprehensive protein tyrosine phosphatase mRNA profiling identifies new regulators in the progression of glioma

Delayed peripheral nerve regeneration and central nervous system collateral sprouting in leucocyte common antigen-related protein tyrosine phosphatase-deficient mice

Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse

Downregulation of protein tyrosine phosphatase PTP-BL represses adipogenesis

Duck lactate dehydrogenase B/epsilon-crystallin gene. Lens recruitment of a GC-promoter

Duck lens epsilon-crystallin and lactate dehydrogenase B4 are identical: a single-copy gene product with two distinct functions.

Effects of LAR and PTP-BL phosphatase deficiency on adult mouse retinal cells activated by lens injury

Effects of dual targeting of tumor cells and stroma in human glioblastoma xenografts with a tyrosine kinase inhibitor against c-MET and VEGFR2

ErbB2, EphrinB1, Src kinase and PTPN13 signaling complex regulates MAP kinase signaling in human cancers

Evolution of eye lens crystallins: the stress connection

Gene duplication and conversion events shaped three homologous, differentially expressed myosin regulatory light chain (MLC2) genes

Genetic variability of the murine creatine kinase B gene locus and related pseudogenes in different inbred strains of mice

Identification and molecular characterization of BP75, a novel bromodomain-containing protein

Identification and sequence analysis of two new members of the SKALP/elafin and SPAI-2 gene family. Biochemical properties of the transglutaminase substrate motif and suggestions for a new nomenclature.

Identification and typing of members of the protein-tyrosine phosphatase gene family expressed in mouse brain

Identification of a novel MET mutation in high-grade glioma resulting in an auto-active intracellular protein

Identification of a novel inactivating mutation in Isocitrate Dehydrogenase 1 (IDH1-R314C) in a high grade astrocytoma.

Immune response in mice that lack the interferon-gamma receptor

Impaired PTPN13 phosphatase activity in spontaneous or HPV-induced squamous cell carcinomas potentiates oncogene signaling through the MAP kinase pathway

Impaired mammary gland development and function in mice lacking LAR receptor-like tyrosine phosphatase activity

Inactivation of LAR family phosphatase genes Ptprs and Ptprf causes craniofacial malformations resembling Pierre-Robin sequence

Isocitrate dehydrogenase 1-mutated human gliomas depend on lactate and glutamate to alleviate metabolic stress

Late cornified envelope (LCE) proteins: distinct expression patterns of LCE2 and LCE3 members suggest nonredundant roles in human epidermis and other epithelia

Maturation of ureter-bladder connection in mice is controlled by LAR family receptor protein tyrosine phosphatases

Mice lacking leukocyte common antigen-related (LAR) protein tyrosine phosphatase domains demonstrate spatial learning impairment in the two-trial water maze and hyperactivity in multiple behavioural tests

Mild impairment of motor nerve repair in mice lacking PTP-BL tyrosine phosphatase activity

Molecular cloning of a mouse epithelial protein-tyrosine phosphatase with similarities to submembranous proteins

Mouse choroideremia gene mutation causes photoreceptor cell degeneration and is not transmitted through the female germline.

Multimerisation of receptor-type protein tyrosine phosphatases PTPBR7 and PTP-SL attenuates enzymatic activity

Multimerization of the protein-tyrosine phosphatase (PTP)-like insulin-dependent diabetes mellitus autoantigens IA-2 and IA-2beta with receptor PTPs (RPTPs). Inhibition of RPTPalpha enzymatic activity

No evidence for involvement of mouse protein-tyrosine phosphatase-BAS-like Fas-associated phosphatase-1 in Fas-mediated apoptosis

One-Tube-Only Standardized Site-Directed Mutagenesis: An Alternative Approach to Generate Amino Acid Substitution Collections

PDZ domains-glue and guide.

PTEN-PDZ domain interactions: binding of PTEN to PDZ domains of PTPN13.

PTPs emerge as PIPs: protein tyrosine phosphatases with lipid-phosphatase activities in human disease ⬇️

Phosphorylation target site specificity for AGC kinases DMPK E and Lats2.

Protein Tyrosine Phosphatase PTPRS Is an Inhibitory Receptor on Human and Murine Plasmacytoid Dendritic Cells

Protein tyrosine phosphatase receptor type R deficient mice exhibit increased exploration in a new environment and impaired novel object recognition memory

Protein tyrosine phosphatase receptor type R is required for Purkinje cell responsiveness in cerebellar long-term depression

Protein tyrosine phosphatase variants in human hereditary disorders and disease susceptibilities ⬇️

Protein tyrosine phosphatases in glioma biology

Protein tyrosine phosphatases in health and disease ⬇️

Protein tyrosine phosphatases: functional inferences from mouse models and human diseases.

Protein tyrosine phosphatases: sequences and beyond

Protein-tyrosine phosphatases expressed in mouse epidermal keratinocytes.

Proteinaceous Regulators and Inhibitors of Protein Tyrosine Phosphatases.

Proteolytic processing of the receptor-type protein tyrosine phosphatase PTPBR7.

Psoriasis-Associated Late Cornified Envelope (LCE) Proteins Have Antibacterial Activity.

Rapid assessment of protein-tyrosine phosphatase expression levels by RT-PCR with degenerate primers

Receptor-like protein tyrosine phosphatases: alike and yet so different

Redox-regulated affinity of the third PDZ domain in the phosphotyrosine phosphatase PTP-BL for cysteine-containing target peptides.

Stimulated regeneration of the crushed adult rat optic nerve correlates with attenuated expression of the protein tyrosine phosphatases RPTPalpha, STEP, and LAR.

Subcellular localization and differentiation-induced redistribution of the protein tyrosine phosphatase PTP-BL in Neuroblastoma cells.

Tailor-Made Protein Tyrosine Phosphatases: In Vitro Site-Directed Mutagenesis of PTEN and PTPRZ-B.

Targeted disruption of the IA-2beta gene causes glucose intolerance and impairs insulin secretion but does not prevent the development of diabetes in NOD mice.

The LAR protein tyrosine phosphatase enables PDGF β-receptor activation through attenuation of the c-Abl kinase activity

The alternative splicing product alpha Ains-crystallin is structurally equivalent to alpha A and alpha B subunits in the rat alpha-crystallin aggregate

The cystatin M/E-cathepsin L balance is essential for tissue homeostasis in epidermis, hair follicles, and cornea.

The gene (PTPN13) encoding the protein tyrosine phosphatase PTP-BL/PTP-BAS is located in mouse chromosome region 5E/F and human chromosome region 4q21

The mouse Ptprr gene encodes two protein tyrosine phosphatases, PTP-SL and PTPBR7, that display distinct patterns of expression during neural development.

The mouse gene Ptprf encoding the leukocyte common antigen-related molecule LAR: cloning, characterization, and chromosomal localization