List of works - Heth Turnquist

A window into immunosuppressant immunoregulation: recipient conversion to rapamycin increases potentially tolerogenic immune cells

scientific article published on 01 April 2014

Adenosine triphosphate-competitive mTOR inhibitors: a new class of immunosuppressive agents that inhibit allograft rejection

scientific article

CCL21-induced immune cell infiltration

scientific article

Calreticulin binds to the alpha1 domain of MHC class I independently of tapasin

scientific article published on 01 January 2002

Controlling the burn and fueling the fire: defining the role for the alarmin interleukin-33 in alloimmunity

scientific article

Cutting edge: Flt3 ligand mediates STAT3-independent expansion but STAT3-dependent activation of myeloid-derived suppressor cells.

scientific article published on 17 March 2014

DAP12 promotes IRAK-M expression and IL-10 production by liver myeloid dendritic cells and restrains their T cell allostimulatory ability.

scientific article published on 21 January 2011

Dendritic cells and regulation of graft-versus-host disease and graft-versus-leukemia activity ⬇️

scientific article published on March 7, 2012

Disparate binding of chaperone proteins by HLA-A subtypes

scientific article published on 22 January 2002

Expansion of Regulatory T Cells In Vitro and In Vivo by IL-33

scientific article published on 01 January 2016

Expression of invariant chain can cause an allele-dependent increase in the surface expression of MHC class I molecules

scientific article

HLA class I polymorphism has a dual impact on ligand binding and chaperone interaction.

scientific article

HLA-B polymorphism affects interactions with multiple endoplasmic reticulum proteins

scientific article published on October 2000

Histone deacetylase inhibition facilitates GM-CSF-mediated expansion of myeloid-derived suppressor cells in vitro and in vivo

scientific article published on 25 October 2011

IL-12hi rapamycin-conditioned dendritic cells mediate IFN-γ-dependent apoptosis of alloreactive CD4+ T cells in vitro and reduce lethal graft-versus-host disease.

scientific article

IL-33 broadens its repertoire to affect DC.

scientific article

IL-33 expands suppressive CD11b+ Gr-1(int) and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival.

scientific article

IL-33 synergizes with TCR and IL-12 signaling to promote the effector function of CD8+ T cells

scientific article published on 13 October 2011

IL33-mediated ILC2 activation and neutrophil IL5 production in the lung response after severe trauma: A reverse translation study from a human cohort to a mouse trauma model.

scientific article

Identity Crisis

scientific article published on 01 February 2016

Immunoregulatory functions of mTOR inhibition.

scientific article

Implications for Interleukin-33 in solid organ transplantation ⬇️

scientific article published on March 27, 2013

In Vivo Mobilization and Functional Characterization of Nonhuman Primate Monocytic Myeloid-Derived Suppressor Cells

scientific article published on 15 September 2015

In situ recruitment of regulatory T cells promotes donor-specific tolerance in vascularized composite allotransplantation

scientific article published on 13 March 2020

Infusion of stably immature monocyte-derived dendritic cells plus CTLA4Ig modulates alloimmune reactivity in rhesus macaques

scientific article published in July 2007

Innate immune cell collaborations instigate transplant tolerance

scientific article published on 13 October 2014

Loss of a glycine in the alpha2 domain affects MHC peptide binding but not chaperone binding

scientific article

Low TCR signal strength induces combined expansion of Th2 and regulatory T cell populations that protect mice from the development of type 1 diabetes

scientific article published on 16 April 2014

Murine dendritic cell rapamycin-resistant and rictor-independent mTOR controls IL-10, B7-H1, and regulatory T-cell induction

scientific article published on 26 February 2013

New dog and new tricks: evolving roles for IL-33 in type 2 immunity

scientific article published on 23 March 2015

PIRs mediate innate myeloid cell memory to nonself MHC molecules

scientific article published on 07 May 2020

Peri-alloHCT IL-33 administration expands recipient T-regulatory cells that protect mice against acute GVHD.

scientific article published on 24 May 2016

Rapamycin augments human DC IL-12p70 and IL-27 secretion to promote allogeneic Type 1 polarization modulated by NK cells

scientific article published on 22 August 2013

Rapamycin-conditioned, alloantigen-pulsed myeloid dendritic cells present donor MHC class I/peptide via the semi-direct pathway and inhibit survival of antigen-specific CD8(+) T cells in vitro and in vivo.

scientific article

Regulators with potential: substantiating myeloid-derived suppressor cells in human organ transplantation

scientific article published on 18 September 2013

Regulatory myeloid cells in transplantation

scientific article

Taming the lions: manipulating dendritic cells for use as negative cellular vaccines in organ transplantation.

scientific article published on August 2008

Tapasin decreases immune responsiveness to a model tumor antigen

scientific article published on July 2004

The IL-33/ST2 axis augments effector T-cell responses during acute GVHD.

scientific article published on 26 March 2015

The amyloid precursor-like protein 2 and the adenoviral E3/19K protein both bind to a conformational site on H-2Kd and regulate H-2Kd expression.

scientific article

The interface between tapasin and MHC class I: identification of amino acid residues in both proteins that influence their interaction

scientific article (publication date: 2002)

Treg-inducing microparticles promote donor-specific tolerance in experimental vascularized composite allotransplantation

scientific article published on 02 December 2019

Tumoral expression of IL-33 inhibits tumor growth and modifies the tumor microenvironment through CD8+ T and NK cells

scientific article

mTOR and GSK-3 shape the CD4+ T-cell stimulatory and differentiation capacity of myeloid DCs after exposure to LPS.

scientific article

mTORC2 Deficiency in Myeloid Dendritic Cells Enhances Their Allogeneic Th1 and Th17 Stimulatory Ability after TLR4 Ligation In Vitro and In Vivo.

scientific article published on 3 April 2015

List of works by Heth Turnquist

A window into immunosuppressant immunoregulation: recipient conversion to rapamycin increases potentially tolerogenic immune cells

Adenosine triphosphate-competitive mTOR inhibitors: a new class of immunosuppressive agents that inhibit allograft rejection

CCL21-induced immune cell infiltration

Calreticulin binds to the alpha1 domain of MHC class I independently of tapasin

Controlling the burn and fueling the fire: defining the role for the alarmin interleukin-33 in alloimmunity

Cutting edge: Flt3 ligand mediates STAT3-independent expansion but STAT3-dependent activation of myeloid-derived suppressor cells.

DAP12 promotes IRAK-M expression and IL-10 production by liver myeloid dendritic cells and restrains their T cell allostimulatory ability.

Dendritic cells and regulation of graft-versus-host disease and graft-versus-leukemia activity ⬇️

Disparate binding of chaperone proteins by HLA-A subtypes

Expansion of Regulatory T Cells In Vitro and In Vivo by IL-33

Expression of invariant chain can cause an allele-dependent increase in the surface expression of MHC class I molecules

HLA class I polymorphism has a dual impact on ligand binding and chaperone interaction.

HLA-B polymorphism affects interactions with multiple endoplasmic reticulum proteins

Histone deacetylase inhibition facilitates GM-CSF-mediated expansion of myeloid-derived suppressor cells in vitro and in vivo

IL-12hi rapamycin-conditioned dendritic cells mediate IFN-γ-dependent apoptosis of alloreactive CD4+ T cells in vitro and reduce lethal graft-versus-host disease.

IL-33 broadens its repertoire to affect DC.

IL-33 expands suppressive CD11b+ Gr-1(int) and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival.

IL-33 synergizes with TCR and IL-12 signaling to promote the effector function of CD8+ T cells

IL33-mediated ILC2 activation and neutrophil IL5 production in the lung response after severe trauma: A reverse translation study from a human cohort to a mouse trauma model.

Identity Crisis

Immunoregulatory functions of mTOR inhibition.

Implications for Interleukin-33 in solid organ transplantation ⬇️

In Vivo Mobilization and Functional Characterization of Nonhuman Primate Monocytic Myeloid-Derived Suppressor Cells

In situ recruitment of regulatory T cells promotes donor-specific tolerance in vascularized composite allotransplantation

Infusion of stably immature monocyte-derived dendritic cells plus CTLA4Ig modulates alloimmune reactivity in rhesus macaques

Innate immune cell collaborations instigate transplant tolerance

Loss of a glycine in the alpha2 domain affects MHC peptide binding but not chaperone binding

Low TCR signal strength induces combined expansion of Th2 and regulatory T cell populations that protect mice from the development of type 1 diabetes

Murine dendritic cell rapamycin-resistant and rictor-independent mTOR controls IL-10, B7-H1, and regulatory T-cell induction

New dog and new tricks: evolving roles for IL-33 in type 2 immunity

PIRs mediate innate myeloid cell memory to nonself MHC molecules

Peri-alloHCT IL-33 administration expands recipient T-regulatory cells that protect mice against acute GVHD.

Rapamycin augments human DC IL-12p70 and IL-27 secretion to promote allogeneic Type 1 polarization modulated by NK cells

Rapamycin-conditioned, alloantigen-pulsed myeloid dendritic cells present donor MHC class I/peptide via the semi-direct pathway and inhibit survival of antigen-specific CD8(+) T cells in vitro and in vivo.

Regulators with potential: substantiating myeloid-derived suppressor cells in human organ transplantation

Regulatory myeloid cells in transplantation

Taming the lions: manipulating dendritic cells for use as negative cellular vaccines in organ transplantation.

Tapasin decreases immune responsiveness to a model tumor antigen

The IL-33/ST2 axis augments effector T-cell responses during acute GVHD.

The amyloid precursor-like protein 2 and the adenoviral E3/19K protein both bind to a conformational site on H-2Kd and regulate H-2Kd expression.

The interface between tapasin and MHC class I: identification of amino acid residues in both proteins that influence their interaction

Treg-inducing microparticles promote donor-specific tolerance in experimental vascularized composite allotransplantation

Tumoral expression of IL-33 inhibits tumor growth and modifies the tumor microenvironment through CD8+ T and NK cells

mTOR and GSK-3 shape the CD4+ T-cell stimulatory and differentiation capacity of myeloid DCs after exposure to LPS.

mTORC2 Deficiency in Myeloid Dendritic Cells Enhances Their Allogeneic Th1 and Th17 Stimulatory Ability after TLR4 Ligation In Vitro and In Vivo.