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List of works by Arwyn T. Jones

A role for the small GTPase Rab21 in the early endocytic pathway

scientific article

Arginine-rich peptides and their internalization mechanisms.

scientific article published on August 2007

BH3 helix-derived biophotonic nanoswitches regulate cytochrome c release in permeabilised cells ⬇️

scientific article published on November 1, 2013

Cell entry of cell penetrating peptides: tales of tails wagging dogs

scientific article published on 10 April 2012

Cell-penetrating antimicrobial peptides - prospectives for targeting intracellular infections

scientific article

Cell-penetrating peptide sequence and modification dependent uptake and subcellular distribution of green florescent protein in different cell lines

scientific article published on 18 April 2019

Cellular internalization and distribution of arginine-rich peptides as a function of extracellular peptide concentration, serum, and plasma membrane associated proteoglycans

scientific article published on 13 February 2008

Cellular uptake of arginine-rich peptides: roles for macropinocytosis and actin rearrangement

scientific article published in December 2004

Cellular uptake, distribution and cytotoxicity of the hydrophobic cell penetrating peptide sequence PFVYLI linked to the proapoptotic domain peptide PAD.

scientific article published on 4 May 2009

Chemical synthesis of cell-permeable apoptotic peptides from in vivo produced proteins.

scientific article

Co-operative Membrane Disruption Between Cell-penetrating Peptide and Cargo: Implications for the Therapeutic Use of the Bcl-2 Converter Peptide D-NuBCP-9-r8 ⬇️

scientific article published on September 20, 2011

Comparison of the endocytic properties of linear and branched PEIs, and cationic PAMAM dendrimers in B16f10 melanoma cells.

scientific article published on 26 October 2006

Contrasting roles for actin in the cellular uptake of cell penetrating peptide conjugates.

scientific article

Control of targeting ligand display by pH-responsive polymers on gold nanoparticles mediates selective entry into cancer cells.

scientific article

Cyanine dye mediated mitochondrial targeting enhances the anti-cancer activity of small-molecule cargoes

scientific article published on 25 March 2020

Design, Synthesis and Evaluation of New Bioactive Oxadiazole Derivatives as Anticancer Agents Targeting Bcl-2

scientific article published on 26 November 2020

Design, synthesis and in vitro anticancer evaluation of 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides

scientific article published on 6 October 2013

Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes.

scientific article published on 20 January 2014

Distal phenylalanine modification for enhancing cellular delivery of fluorophores, proteins and quantum dots by cell penetrating peptides

scientific article

Disulfiram-induced cytotoxicity and endo-lysosomal sequestration of zinc in breast cancer cells

scientific article

Dynamic colocalization microscopy to characterize intracellular trafficking of nanomedicines

scientific article published on 10 October 2011

Ecosystem type drives soil eukaryotic diversity and composition in Europe

scientific article published in 2023

Effects of Na+/H+ exchanger inhibitors on subcellular localisation of endocytic organelles and intracellular dynamics of protein transduction domains HIV-TAT peptide and octaarginine

scientific article published on 14 July 2006

Electrospray mass spectrometric evidence for the occurrence of two major variants in native pig pepsin A.

scientific article published on January 1996

Endocytosis, intracellular traffic and fate of cell penetrating peptide based conjugates and nanoparticles.

scientific article

Establishment of subcellular fractionation techniques to monitor the intracellular fate of polymer therapeutics I. Differential centrifugation fractionation B16F10 cells and use to study the intracellular fate of HPMA copolymer - doxorubicin.

scientific article published on July 2006

Flotillin-dependent endocytosis and a phagocytosis-like mechanism for cellular internalization of disulfide-based poly(amido amine)/DNA polyplexes.

scientific article published on 22 January 2011

Fluorescence labelling of extracellular vesicles using a novel thiol-based strategy for quantitative analysis of cellular delivery and intracellular traffic

scientific article

Guanidine-Containing Molecular Transporters: Sorbitol-Based Transporters Show High Intracellular Selectivity toward Mitochondria

scholarly article by Kaustabh K. Maiti et al published 3 August 2007 in Angewandte Chemie International Edition

Human pepsin 3b peptide map sequence analysis, genotype and hydrophobic nature

scientific article published on 01 August 1993

Inhibition of Endosome Fusion by Wortmannin Persists in the Presence of Activated rab5 ⬇️

scientific article published on February 1, 1998

Inhibition of calcium-independent mannose 6-phosphate receptor incorporation into trans-Golgi network-derived clathrin-coated vesicles by wortmannin

scientific article published on September 1997

Inhibition of in vitro endosomal vesicle fusion activity by aminoglycoside antibiotics

scientific article published on September 1998

Interleukin-4-inducing principle from Schistosoma mansoni eggs contains a functional C-terminal nuclear localization signal necessary for nuclear translocation in mammalian cells but not for its uptake.

scientific article

Intracellular Drug Delivery. Workshop Report from the 28th International Symposium on Controlled Release of Bioactive Materials, San Diego, 23–24 June 2001 ⬇️

scientific article published on December 1, 2001

Intracellular traffic and fate of protein transduction domains HIV-1 TAT peptide and octaarginine. Implications for their utilization as drug delivery vectors

scientific article published on January 2006

Intracellular trafficking pathways and drug delivery: fluorescence imaging of living and fixed cells.

scientific article

Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells

scientific article published on 14 October 2006

Involvement of the endosomal autoantigen EEA1 in homotypic fusion of early endosomes.

scientific article published on July 1998

Low concentration thresholds of plasma membranes for rapid energy-independent translocation of a cell-penetrating peptide

scientific article

Macropinocytosis: searching for an endocytic identity and role in the uptake of cell penetrating peptides

scientific article published on July 2007

Mycolic acids, a promising mycobacterial ligand for targeting of nanoencapsulated drugs in tuberculosis

scientific article published on 6 June 2015

Nanomedicines for the Delivery of Biologics

scientific article published on 03 May 2019

Nanoparticle geometry and surface orientation influence mode of cellular uptake.

scientific article published on 22 February 2013

Novel cis-selective and non-epimerisable C3 hydroxy azapodophyllotoxins targeting microtubules in cancer cells

scientific article published on 23 December 2015

Novel monodisperse PEG-dendrons as new tools for targeted drug delivery: synthesis, characterization and cellular uptake

scientific article

Peptide maps of five human pepsin isoenzymes and other aspartic proteinases

scientific article published on 01 May 1992

Phosphatidylinositol 3-kinase activity is required for early endosome fusion.

scientific article

Phosphatidylinositol 3-kinase regulation of fluid phase endocytosis

scientific article

Post-pegylated lipoplexes are promising vehicles for gene delivery in RPE cells

scientific article published on 5 June 2007

Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitors of varicella zoster virus

scientific article published on 22 October 2007

Rab7b modulates autophagic flux by interacting with Atg4B.

scientific article published on 23 August 2017

Receptor Crosslinking: A General Method to Trigger Internalization and Lysosomal Targeting of Therapeutic Receptor:Ligand Complexes.

scientific article

Regulation of Early Endosome Fusion by Phospholipase D Activity ⬇️

scientific article published on July 18, 1997

Regulation of early-endosome dynamics by phosphatidylinositol 3-phosphate binding proteins.

scientific article published on August 1999

Regulation of endosome fusion.

scientific article

Switching of Macromolecular Ligand Display by Thermoresponsive Polymers Mediates Endocytosis of Multiconjugate Nanoparticles.

scientific article published on 26 February 2018

Synthesis and evaluation of 3-(benzylthio)-5-(1H-indol-3-yl)-1,2,4-triazol-4-amines as Bcl-2 inhibitory anticancer agents

scientific article published on 14 February 2013

Synthesis and evaluation of 5-(1H-indol-3-yl)-N-aryl-1,3,4-oxadiazol-2-amines as Bcl-2 inhibitory anticancer agents.

scientific article published on 27 December 2016

Temperature-, concentration- and cholesterol-dependent translocation of L- and D-octa-arginine across the plasma and nuclear membrane of CD34+ leukaemia cells.

scientific article published on April 2007

The Role of BCA2 in the Endocytic Trafficking of EGFR and Significance as a Prognostic Biomarker in Cancer.

scientific article published on 09 December 2016

The pH sensitive probe 5-(and-6)-carboxyl seminaphthorhodafluor is a substrate for the multidrug resistance-related protein MRP1.

scientific article

The use of inhibitors to study endocytic pathways of gene carriers: optimization and pitfalls

scientific article published on 15 December 2009

Tuning the pH sensitivities of orthoester based compounds for drug delivery applications by simple chemical modification

scientific article published on 13 February 2010

Understanding endocytic pathways and intracellular trafficking: a prerequisite for effective design of advanced drug delivery systems

scientific article published on 01 November 2003

Virtual screening, SAR, and discovery of 5-(indole-3-yl)-2-[(2-nitrophenyl)amino] [1,3,4]-oxadiazole as a novel Bcl-2 inhibitor

scientific article published on 9 January 2017

Visualizing Actin Architectures in Cells Incubated with Cell-Penetrating Peptides.

scientific article published on January 2015

siRNA Inhibition of Endocytic Pathways to Characterize the Cellular Uptake Mechanisms of Folate-Functionalized Glycol Chitosan Nanogels.

scientific article

siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat.

scientific article

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