Search filters

List of works by Mario Mellado

1.61 T-cells expressing TLR4 and CXCR4 are associated with an RA diagnostic in early inflammatory arthritis

A framework for computational and experimental methods: Identifying dimerization residues in CCR chemokine receptors

scientific article published on 01 September 2005

A novel MEK-ERK-AMPK signaling axis controls chemokine receptor CCR7-dependent survival in human mature dendritic cells

scientific article

A potential immune escape mechanism by melanoma cells through the activation of chemokine-induced T cell death

scientific article published on 01 May 2001

Agent-based model of macrophage action on endocrine pancreas

scientific article published on January 2012

Autocrine production of IFN-gamma by macrophages controls their recruitment to kidney and the development of glomerulonephritis in MRL/lpr mice

scientific article published on 01 July 2002

Blockade of endothelial G(i) protein enhances early engraftment in intraportal cell transplant to mouse liver

scientific article published in January 2012

CCL2 Shapes Macrophage Polarization by GM-CSF and M-CSF: Identification of CCL2/CCR2-Dependent Gene Expression Profile

scientific article published on 17 March 2014

CCR5/CD4/CXCR4 oligomerization prevents HIV-1 gp120IIIB binding to the cell surface

scientific article

CCR7-mediated physiological lymphocyte homing involves activation of a tyrosine kinase pathway

scientific article (publication date: 2003)

CD69 modulates sphingosine-1-phosphate-induced migration of skin dendritic cells

scientific article published on 17 March 2011

CXCL12 Regulates through JAK1 and JAK2 Formation of Productive Immunological Synapses

scientific article published on 27 April 2015

CXCL12-mediated murine neural progenitor cell movement requires PI3Kβ activation

scientific article published on 19 April 2013

CXCL13/CXCR5 signaling enhances BCR-triggered B-cell activation by shaping cell dynamics ⬇️

scientific article published on June 9, 2011

CXCR3 chemokine receptor distribution in normal and inflamed tissues: expression on activated lymphocytes, endothelial cells, and dendritic cells

scientific article published on 01 March 2001

CXCR4-mediated suppressor of cytokine signaling up-regulation inactivates growth hormone function.

scientific article published on 10 August 2004

Chapter 5. Multiple approaches to the study of chemokine receptor homo- and heterodimerization.

scientific article

Characterization of monoclonal antibodies specific for the human growth hormone 22K and 20K isoforms

scientific article published on 01 April 1996

Chemokine Detection Using Receptors Immobilized on an SPR Sensor Surface.

scientific article published on 14 November 2015

Chemokine control of HIV-1 infection

Chemokine receptor 2 blockade prevents asthma in a cynomolgus monkey model

scientific article published on 20 November 2007

Chemokine receptor dimerization and chemotaxis.

scientific article published on January 2009

Chemokine receptor dimerization: two are better than one.

scientific article published in November 2001

Chemokine receptor oligomerization: a further step toward chemokine function.

scientific article published on July 2012

Chemokine receptor oligomerization: functional considerations.

scientific article published on 12 October 2009

Chemokine signaling and functional responses: the role of receptor dimerization and TK pathway activation.

scientific article

Chemokine signaling defines novel targets for therapeutic intervention.

scientific article

Chemokines integrate JAK/STAT and G‐protein pathways during chemotaxis and calcium flux responses ⬇️

scientific article published on May 1, 2003

Comprehensive analysis of lymph node stroma-expressed Ig superfamily members reveals redundant and nonredundant roles for ICAM-1, ICAM-2, and VCAM-1 in lymphocyte homing

scientific article

DC-SIGN ligation on dendritic cells results in ERK and PI3K activation and modulates cytokine production.

scientific article published on 24 January 2006

DeltahGHR, a novel biosafe cell surface-labeling molecule for analysis and selection of genetically transduced human cells.

scientific article

Determination of human growth hormone in human serum samples by surface plasmon resonance immunoassay

scientific article published on 20 January 2009

Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7

scholarly article

Drug testing in cellular chemotaxis assays

scientific article published on 01 June 2008

Dynamic Regulation of CXCR1 and CXCR2 Homo- and Heterodimers

scientific article published on 04 November 2009

EBI2 regulates CXCL13-mediated responses by heterodimerization with CXCR5.

scientific article published on 22 August 2012

Epithelial chemokine CXCL14 synergizes with CXCL12 via allosteric modulation of CXCR4.

scientific article

Expression analysis of the thyrotropin-releasing hormone receptor (TRHR) in the immune system using agonist anti-TRHR monoclonal antibodies.

scientific article published on May 1999

Growth Hormone Reprograms Macrophages toward an Anti-Inflammatory and Reparative Profile in an MAFB-Dependent Manner

scientific article published on 26 June 2020

Growth hormone prevents the development of autoimmune diabetes

scientific article

HIV-1 envelope protein gp120 triggers a Th2 response in mice that shifts to Th1 in the presence of human growth hormone

scientific article published in July 1998

HIV-1 infection through the CCR5 receptor is blocked by receptor dimerization.

scholarly article

HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4

scientific article

Healthy and Osteoarthritic Synovial Fibroblasts Produce a Disintegrin and Metalloproteinase with Thrombospondin Motifs 4, 5, 7, and 12: Induction by IL-1β and Fibronectin and Contribution to Cartilage Damage.

scientific article published on 19 July 2016

High mobility group box 1 orchestrates tissue regeneration via CXCR4.

scientific article published on 4 December 2017

Identification of amino acid residues crucial for chemokine receptor dimerization.

scientific article published on 11 January 2004

Implementation of a SPR immunosensor for the simultaneous detection of the 22K and 20K hGH isoforms in human serum samples.

scientific article published on 30 April 2013

Janus kinases 1 and 2 regulate chemokine-mediated integrin activation and naïve T-cell homing.

scientific article

Leukocyte attraction through the CCR5 receptor controls progress from insulitis to diabetes in non-obese diabetic mice.

scientific article published in February 2004

Ligand stabilization of CXCR4/delta-opioid receptor heterodimers reveals a mechanism for immune response regulation.

scientific article published on February 2008

Methods to immobilize GPCR on the surface of SPR sensors.

scientific article published on January 2015

Monocyte chemoattractant protein-1-induced CCR2B receptor desensitization mediated by the G protein-coupled receptor kinase 2 ⬇️

scientific article published on March 17, 1998

Opioids trigger alpha 5 beta 1 integrin-mediated monocyte adhesion

scientific article published on February 2006

PI3Kgamma activation by CXCL12 regulates tumor cell adhesion and invasion.

scientific article

Real-time detection of the chemokine CXCL12 in urine samples by surface plasmon resonance

scientific article published on 13 February 2013

Regulation of macrophage activation and septic shock susceptibility via p21(WAF1/CIP1).

scientific article published in March 2009

Remodeling our concept of chemokine receptor function: From monomers to oligomers

scientific article published on 02 May 2018

Separating Actin-Dependent Chemokine Receptor Nanoclustering from Dimerization Indicates a Role for Clustering in CXCR4 Signaling and Function

scientific article published in April 2018

Similarities and differences in RANTES- and (AOP)-RANTES-triggered signals: implications for chemotaxis

scientific article published on February 1999

Single- and multi-analyte determination of gonadotropic hormones in urine by Surface Plasmon Resonance immunoassay.

scientific article published on 7 June 2009

Structures of T Cell Immunoglobulin Mucin Protein 4 Show a Metal-Ion-Dependent Ligand Binding Site where Phosphatidylserine Binds

scientific article

Suppressor of cytokine signaling 1 blocks mitosis in human melanoma cells.

scientific article

Surface plasmon resonance immunoassay analysis of pituitary hormones in urine and serum samples

scientific article published on 27 January 2009

T Cell Migration in Rheumatoid Arthritis

scientific article

Technical advance: Surface plasmon resonance-based analysis of CXCL12 binding using immobilized lentiviral particles

scientific article published on 18 May 2011

Th17 polarization of memory Th cells in early arthritis: the vasoactive intestinal peptide effect

scientific article published on 8 May 2015

The atypical receptor CCRL2 is required for CXCR2-dependent neutrophil recruitment and tissue damage

scientific article published on 25 July 2017

The chemokine SDF-1alpha triggers a chemotactic response and induces cell polarization in human B lymphocytes.

scientific article published in July 1998

Type I phosphatidylinositol 4-phosphate 5-kinase homo- and heterodimerization determines its membrane localization and activity.

scientific article published on 24 February 2015

Use of Lentiviral Particles As a Cell Membrane-Based mFasL Delivery System for In Vivo Treatment of Inflammatory Arthritis.

scientific article

Use of Resonance Energy Transfer Techniques for In Vivo Detection of Chemokine Receptor Oligomerization

scientific article published in January 2016

Vasoactive intestinal peptide maintains the nonpathogenic profile of human th17-polarized cells

scientific article published on 08 May 2014

Wnt and RUNX2 mediate cartilage breakdown by osteoarthritis synovial fibroblast-derived ADAMTS-7 and -12

scientific article published on 22 March 2019

Paulina is supported by:

About Paulina

Help