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List of works by Madalena Maria de Magalhães Pinto

1,2-Dihydroxyxanthone: Effect on A375-C5 Melanoma Cell Growth Associated with Interference with THP-1 Human Macrophage Activity

scientific article published on 04 June 2019

1-Hydr-oxy-3-(3-methyl-but-2-en-yloxy)xanthone

scientific article published on 13 October 2009

5,7-Dihydroxychromones and 8-hydroxytetrahydrochromones from Horsfieldia irya.

scientific article

A New Dihydrochromone Dimer and Other Secondary Metabolites from Cultures of the Marine Sponge-Associated Fungi Neosartorya fennelliae KUFA 0811 and Neosartorya tsunodae KUFC 9213. ⬇️

scientific article

A New Linalool Derivative and Other Constituents fromPiper ribesoides

scientific article published on 01 April 1989

A New Meroditerpene and a New Tryptoquivaline Analog from the Algicolous Fungus Neosartorya takakii KUFC 7898. ⬇️

scientific article published on 15 June 2015

A New Meroterpene, A New Benzofuran Derivative and Other Constituents from Cultures of the Marine Sponge-Associated Fungus Acremonium persicinum KUFA 1007 and Their Anticholinesterase Activities ⬇️

scientific article published on 25 June 2019

A new cyclic hexapeptide and a new isocoumarin derivative from the marine sponge-associated fungus Aspergillus similanensis KUFA 0013. ⬇️

scientific article

A novel curcumin derivative which inhibits P-glycoprotein, arrests cell cycle and induces apoptosis in multidrug resistance cells.

scientific article published on 19 November 2016

Absolute Stereochemistry Determination of Bioactive Marine-Derived Cyclopeptides by Liquid Chromatography Methods: An Update Review (2018–2022)

scientific article published in 2023

Antibacterial and antibiofilm activities of the metabolites isolated from the culture of the mangrove-derived endophytic fungus Eurotium chevalieri KUFA 0006.

scientific article published on 03 June 2017

Anticancer and cancer preventive compounds from edible marine organisms

scientific article published on 6 April 2017

Antifouling potential of Nature-inspired sulfated compounds.

scientific article published on 13 February 2017

Antithrombotics from the Sea: Polysaccharides and Beyond

scientific article published on 16 March 2019

Antitumor Activity of Quinazolinone Alkaloids Inspired by Marine Natural Products

scientific article published on 31 July 2018

Antitumor Activity of Some Prenylated Xanthones.

scientific article published on 11 August 2009

Artelastocarpin and carpelastofuran, two new flavones, and cytotoxicities of prenyl flavonoids from Artocarpus elasticus against three cancer cell lines.

scientific article published in December 2001

BDDE-Inspired Chalcone Derivatives to Fight Bacterial and Fungal Infections

scientific article published on 08 May 2022

Bioactive xanthones with effect on P-glycoprotein and prediction of intestinal absorption

Bis-Indolyl Benzenoids, Hydroxypyrrolidine Derivatives and Other Constituents from Cultures of the Marine Sponge-Associated Fungus Aspergillus candidus KUFA0062. ⬇️

scientific article published on 6 April 2018

Boronic Acids and Their Derivatives in Medicinal Chemistry: Synthesis and Biological Applications

scientific article published on 21 September 2020

Bromoalkoxyxanthones as promising antitumor agents: synthesis, crystal structure and effect on human tumor cell lines.

scientific article

Carboxyxanthones: Bioactive Agents and Molecular Scaffold for Synthesis of Analogues and Derivatives

scientific article published on 05 January 2019

Chemistry of the fumiquinazolines and structurally related alkaloids

scientific article published on 09 August 2018

Chiral Derivatives of Xanthones with Antimicrobial Activity

scientific article published on 16 January 2019

Chiral Separations in Preparative Scale: A Medicinal Chemistry Point of View

scientific article published on 21 April 2020

Chiral Stationary Phases for Liquid Chromatography: Recent Developments

scientific article published on 28 February 2019

Chiral Thioxanthones as Modulators of P-glycoprotein: Synthesis and Enantioselectivity Studies.

scientific article published on 10 March 2018

Chiral enantioresolution of cathinone derivatives present in "legal highs", and enantioselectivity evaluation on cytotoxicity of 3,4-methylenedioxypyrovalerone (MDPV)

scientific article published on 13 June 2016

Chromone Derivatives and Other Constituents from Cultures of the Marine Sponge-Associated Fungus KUFA0220 and Their Antibacterial Activity ⬇️

article

Clionasterol: a potent inhibitor of complement component C1.

scientific article published in February 2003

Computational studies of new potential antimalarial compounds--stereoelectronic complementarity with the receptor

scientific article published in September 2003

Constituents ofPolyalthia jucunda. and Their Cytotoxic Effect on Human Cancer Cell Lines

Constituents ofSchisandra verruculosa. and Their Cytotoxic Effect on Human Cancer Cell Lines ⬇️

Cytotoxic activity of lupane-type triterpenes from Glochidion sphaerogynum and Glochidion eriocarpum two of which induce apoptosis.

scientific article

Cytotoxicities of xanthones and cinnamate esters from Hypericum hookerianum

scientific article

Cytotoxicity of prenylated xanthones and other constituents from the wood of Garcinia merguensis.

scientific article

Definition of an electronic profile of compounds with inhibitory activity against hematin aggregation in malaria parasite

scientific article published on June 2004

Design and synthesis of new inhibitors of p53–MDM2 interaction with a chalcone scaffold

Development and characterization of PLGA nanoparticles containing 1,3-dihydroxy-2-methylxanthone with improved antitumor activity on a human breast cancer cell line

scientific article published on 29 July 2019

Development and characterization of PLGA nanospheres and nanocapsules containing xanthone and 3-methoxyxanthone.

scientific article

Development of noncytotoxic PLGA nanoparticles to improve the effect of a new inhibitor of p53-MDM2 interaction

scientific article published on 12 July 2013

Dihydroxyxanthones prenylated derivatives: Synthesis, structure elucidation, and growth inhibitory activity on human tumor cell lines with improvement of selectivity for MCF-7

scientific article published on 23 June 2007

Discovery of a New Xanthone against Glioma: Synthesis and Development of (Pro)liposome Formulations

article

Drug-like Properties and ADME of Xanthone Derivatives: The Antechamber of Clinical Trials.

scientific article published on 25 April 2016

Dual anticoagulant/antiplatelet persulfated small molecules

scientific article published on 15 March 2011

Dual inhibitors of P-glycoprotein and tumor cell growth: (re)discovering thioxanthones.

scientific article

Effect of abietane diterpenes from Plectranthus grandidentatus on T- and B-lymphocyte proliferation.

scientific article published in January 2004

Effect of abietane diterpenes from Plectranthus grandidentatus on the growth of human cancer cell lines.

scientific article published in September 2002

Effect of sprouting and light cycle on antioxidant activity of Brassica oleracea varieties.

scientific article published on 2 June 2014

Effects of natural prenylated flavones in the phenotypical ER (+) MCF-7 and ER (-) MDA-MB-231 human breast cancer cells

scientific article published on 20 December 2005

Efficacy, Stability, and Safety Evaluation of New Polyphenolic Xanthones Towards Identification of Bioactive Compounds to Fight Skin Photoaging

scientific article published on 16 June 2020

Emerging sulfated flavonoids and other polyphenols as drugs: nature as an inspiration.

scientific article published on 28 March 2013

Enantiomeric Resolution and Docking Studies of Chiral Xanthonic Derivatives on Chirobiotic Columns

scientific article

Enantiomeric resolution of kielcorin derivatives by HPLC on polysaccharide stationary phases using multimodal elution

scientific article published in May 2004

Enantioresolution of chiral derivatives of xanthones on (S,S)-Whelk-O1 and L-phenylglycine stationary phases and chiral recognition mechanism by docking approach for (S,S)-Whelk-O1.

scientific article

Enantioselective Synthesis, Enantiomeric Separations and Chiral Recognition

scientific article published on 08 April 2020

Enantioseparation and chiral recognition mechanism of new chiral derivatives of xanthones on macrocyclic antibiotic stationary phases

scientific article published on 11 April 2012

Enhanced cytotoxicity of prenylated chalcone against tumour cells via disruption of the p53-MDM2 interaction.

scientific article published on 14 October 2015

Erubescensoic Acid, a New Polyketide and a Xanthonopyrone SPF-3059-26 from the Culture of the Marine Sponge-Associated Fungus KUFA 0220 and Antibacterial Activity Evaluation of Some of Its Constituents ⬇️

article

Evaluation of 2',4'-dihydroxy-3,4,5-trimethoxychalcone as antimitotic agent that induces mitotic catastrophe in MCF-7 breast cancer cells.

scientific article published on 23 June 2014

Flavonoid Glycosides with a Triazole Moiety for Marine Antifouling Applications: Synthesis and Biological Activity Evaluation

scientific article published on 24 December 2020

Flavonoids with an oligopolysulfated moiety: a new class of anticoagulant agents.

scientific article published on 7 December 2010

From Natural Products to New Synthetic Small Molecules: A Journey through the World of Xanthones

scientific article published in 2021

From Natural Xanthones to Synthetic C-1 Aminated 3,4-Dioxygenated Xanthones as Optimized Antifouling Agents

scientific article published on 13 November 2021

Hemisynthetic secofriedelane triterpenes with inhibitory activity against the growth of human tumor cell lines in vitro.

scientific article

Hepatoprotective activity of xanthones and xanthonolignoids against tert-butylhydroperoxide-induced toxicity in isolated rat hepatocytes--comparison with silybin

scientific article published on 01 November 1995

Improvement of the inhibitory effect of xanthones on NO production by encapsulation in PLGA nanocapsules

scientific article published in February 2005

Induction and activation of P-glycoprotein by dihydroxylated xanthones protect against the cytotoxicity of the P-glycoprotein substrate paraquat

scientific article published on 25 January 2014

Inhibition of inflammatory responses by a series of novel dolabrane derivatives

article

Insights into the in vitro antitumor mechanism of action of a new pyranoxanthone.

scientific article

Isolation and Potential Biological Applications of Haloaryl Secondary Metabolites from Macroalgae

scientific article published on 22 January 2019

Lichen Xanthones as Models for New Antifungal Agents

scientific article published on 12 October 2018

Marine Natural Peptides: Determination of Absolute Configuration Using Liquid Chromatography Methods and Evaluation of Bioactivities.

scientific article published on 31 January 2018

Marine Natural Products as Models to Circumvent Multidrug Resistance

scientific article

Marine natural flavonoids: chemistry and biological activities

scientific article published on 04 May 2018

Marine-Derived Compounds with Potential Use as Cosmeceuticals and Nutricosmetics

scientific article published on 29 May 2020

Medicinal Chemistry Strategies to Disrupt the p53-MDM2/MDMX Interaction.

scientific article published on 15 June 2016

Merodrimanes and Other Constituents from Talaromyces thailandiasis

scientific article published on 31 May 2007

Metabolites from Marine-Derived Fungi as Potential Antimicrobial Adjuvants

scientific article published in 2021

Modulation of Autophagy by a Thioxanthone Decreases the Viability of Melanoma Cells.

scientific article published on 10 October 2016

Multidimensional optimization of promising antitumor xanthone derivatives.

scientific article published on 6 April 2013

Naphthoquinoxaline metabolite of mitoxantrone is less cardiotoxic than the parent compound and it can be a more cardiosafe drug in anticancer therapy

scientific article published on 14 September 2016

New Alkoxy Flavone Derivatives Targeting Caspases: Synthesis and Antitumor Activity Evaluation

scientific article published on 31 December 2018

New Cyclotetrapeptides and a New Diketopiperzine Derivative from the Marine Sponge-Associated Fungus Neosartorya glabra KUFA 0702. ⬇️

scientific article published on 20 July 2016

New Polyketides and New Benzoic Acid Derivatives from the Marine Sponge-Associated Fungus Neosartorya quadricincta KUFA 0081 ⬇️

scientific article published on 16 July 2016

New Uses for Old Drugs: Pharmacophore‐Based Screening for the Discovery of P‐Glycoprotein Inhibitors ⬇️

scientific article published on March 29, 2011

New chiral derivatives of xanthones: synthesis and investigation of enantioselectivity as inhibitors of growth of human tumor cell lines

scientific article published on 31 December 2013

New chiral stationary phases based on xanthone derivatives for liquid chromatography

scientific article

New isocoumarin derivatives and meroterpenoids from the marine sponge-associated fungus Aspergillus similanensis sp. nov. KUFA 0013 ⬇️

scientific article

New marine-derived indolymethyl pyrazinoquinazoline alkaloids with promising antimicrobial profiles

scientific article published on 21 August 2020

Norhierridin B, a New Hierridin B-Based Hydroquinone with Improved Antiproliferative Activity

scientific article published on 30 March 2020

Old Drugs as New Treatments for Neurodegenerative Diseases

scientific article published on 11 May 2018

One Step Forward towards the Development of Eco-Friendly Antifouling Coatings: Immobilization of a Sulfated Marine-Inspired Compound

scientific article published on 25 September 2020

P-glycoprotein induction in Caco-2 cells by newly synthetized thioxanthones prevents paraquat cytotoxicity.

scientific article

Parkinson disease mutant E46K enhances α-synuclein phosphorylation in mammalian cell lines, in yeast, and in vivo

scientific article

Polyoxygenated cyclohexene derivatives from Ellipeiopsis cherrevensis

scientific article published in March 2002

Polysulfated xanthones: multipathway development of a new generation of dual anticoagulant/antiplatelet agents.

scientific article published on 18 July 2011

Potential small-molecule activators of caspase-7 identified using yeast-based caspase-3 and -7 screening assays

scientific article published on 04 January 2014

Prenylated Chalcone 2 Acts as an Antimitotic Agent and Enhances the Chemosensitivity of Tumor Cells to Paclitaxel.

scientific article published on 29 July 2016

Prenylated derivatives of baicalein and 3,7-dihydroxyflavone: synthesis and study of their effects on tumor cell lines growth, cell cycle and apoptosis.

scientific article published on 30 March 2011

Psoralen analogues: synthesis, inhibitory activity of growth of human tumor cell lines and computational studies.

scientific article published on 24 January 2006

Pyranoxanthones: Synthesis, growth inhibitory activity on human tumor cell lines and determination of their lipophilicity in two membrane models

scientific article published on 18 September 2013

Quantification of 1-(propan-2-ylamino)-4-propoxy-9H-thioxanthen-9-one (TX5), a newly synthetized P-glycoprotein inducer/activator, in biological samples: method development and validation.

scientific article

Quantification of a Sulfated Marine-Inspired Antifouling Compound in Several Aqueous Matrices: Biodegradation Studies and Leaching Assays from Polydimethylsiloxane Coatings

scientific article published in 2022

Recent Advances in Bioactive Flavonoid Hybrids Linked by 1,2,3-Triazole Ring Obtained by Click Chemistry

publication published on 30 December 2021

Receptor-drug association studies in the inhibition of the hematin aggregation process of malaria

scientific article

Resolution and determination of enantiomeric purity of new chiral derivatives of xanthones using polysaccharide-based stationary phases

scientific article published on 25 July 2012

Resolution, determination of enantiomeric purity and chiral recognition mechanism of new xanthone derivatives on (S,S)-whelk-O1 stationary phase.

scientific article published on 25 April 2017

Screening a Small Library of Xanthones for Antitumor Activity and Identification of a Hit Compound which Induces Apoptosis

scientific article published on 13 January 2016

Solid-phase synthesis of 2'-hydroxychalcones. Effects on cell growth inhibition, cell cycle and apoptosis of human tumor cell lines

scientific article

Strategies to Overcome Heparins' Low Oral Bioavailability

scientific article

Structure and Ligand-based Design of P-glycoprotein Inhibitors: A Historical Perspective ⬇️

scientific article published on January 1, 2012

Structure based design, synthesis, and evaluation of potential inhibitors of steroid sulfatase

scientific article

Structure-Antifouling Activity Relationship and Molecular Targets of Bio-Inspired(thio)xanthones

scientific article published on 30 July 2020

Structure-activity relationship studies for multitarget antithrombotic drugs

scientific article published on 15 November 2016

Structures, Activities and Drug-Likeness of Anti-Infective Xanthone Derivatives Isolated from the Marine Environment: A Review

scientific article published on 10 January 2019

Substituted xanthones as selective and reversible monoamine oxidase A (MAO-A) inhibitors

scientific article published in August 1993

Sulfated small molecules targeting eBV in Burkitt lymphoma: from in silico screening to the evidence of in vitro effect on viral episomal DNA.

scientific article

Synergistic Effects Between Thioxanthones and Oxacillin Against Methicillin-Resistant Staphylococcus aureus.

scientific article published on 19 March 2015

Synthesis and Antitumor Evaluation of Benzopsoralen Analogues

scientific article published on 01 May 2007

Synthesis and antimalarial properties of new chloro-9H-xanthones with an aminoalkyl side chain

scientific article published on July 2007

Synthesis of Coumarins and Derivatives. Part 1. Biomimetic synthesis of esculetin and halogenated derivatives

Synthesis of N-aryl-5-amino-4-cyanopyrazole derivatives as potent xanthine oxidase inhibitors

scientific article published on 05 July 2007

Synthesis of New Glycosylated Flavonoids with Inhibitory Activity on Cell Growth

scientific article published on 05 May 2018

Synthesis of New Proteomimetic Quinazolinone Alkaloids and Evaluation of Their Neuroprotective and Antitumor Effects

scientific article published on 01 February 2019

Synthesis of a natural chalcone and its prenyl analogs--evaluation of tumor cell growth-inhibitory activities, and effects on cell cycle and apoptosis

scientific article

Synthesis of new chiral xanthone derivatives acting as nerve conduction blockers in the rat sciatic nerve

scientific article published on 2 July 2012

Synthesis, Biological Evaluation, and In Silico Studies of Novel Aminated Xanthones as Potential p53-Activating Agents

scientific article published on 22 May 2019

Synthetic Chiral Derivatives of Xanthones: Biological Activities and Enantioselectivity Studies

scientific article published on 22 February 2019

Synthetic secofriedelane and friedelane derivatives as inhibitors of human lymphocyte proliferation and growth of human cancer cell lines in vitro.

scientific article

The Antitumor Activity of a Lead Thioxanthone is Associated with Alterations in Cholesterol Localization

scientific article published on 12 December 2018

The binding of xanthone derivatives to transthyretin.

scientific article published on 19 October 2005

The importance of drug metabolites synthesis: the case-study of cardiotoxic anticancer drugs

scientific article published on 10 April 2017

Three decades of P-gp inhibitors: skimming through several generations and scaffolds.

scientific article published on January 2012

Transcription profiling of the Neurospora crassa response to a group of synthetic (thio)xanthones and a natural acetophenone

scientific article

Xanthone derivatives: new insights in biological activities.

scientific article

Xanthones as inhibitors of growth of human cancer cell lines and their effects on the proliferation of human lymphocytes in vitro.

scientific article published in December 2002

Xanthones from Calophyllum teysmannii var. inophylloide

scientific article published on 01 April 2000

Xanthones from Calophyllum teysmannii var. inophylloide.

scientific article

Α-mangostin and gambogic acid as potential inhibitors of the p53-MDM2 interaction revealed by a yeast approach.

scientific article published on 29 March 2013

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