List of works - Bart Cornelissen

111In-BnDTPA-F3: an Auger electron-emitting radiotherapeutic agent that targets nucleolin

scientific article published on 20 February 2012

123/125I-labelled 2-iodo-L: -phenylalanine and 2-iodo-D: -phenylalanine: comparative uptake in various tumour types and biodistribution in mice.

scientific article published on 30 March 2006

18F-Trifluoromethanesulfinate Enables Direct C-H 18F-Trifluoromethylation of Native Aromatic Residues in Peptides

scientific article published on 13 January 2020

A Carbon-Fiber Sheet Resistor for MR-, CT-, SPECT-, and PET-Compatible Temperature Maintenance in Small Animals

scientific article published on 01 June 2019

A comparison of the behavior of (64)Cu-acetate and (64)Cu-ATSM in vitro and in vivo

scientific article published on 12 December 2013

A dual radiolabelling approach for tracking metal complexes: investigating the speciation of copper bis(thiosemicarbazonates) in vitro and in vivo

scientific article

Amplification of DNA damage by a γH2AX-targeted radiopharmaceutical.

scientific article

Associations between the uptake of 111In-DTPA-trastuzumab, HER2 density and response to trastuzumab (Herceptin) in athymic mice bearing subcutaneous human tumour xenografts.

scientific article

Bioorthogonal chemistry: implications for pretargeted nuclear (PET/SPECT) imaging and therapy

scientific article published on 20 March 2014

Call to arms: need for radiobiology in molecular radionuclide therapy

scientific article published on 08 May 2019

Can γH2AX be used to personalise cancer treatment?

scientific article published on December 2013

Cell penetrating peptides for in vivo molecular imaging applications.

scientific article published on January 2008

Chlorambucil targets BRCA1/2-deficient tumours and counteracts PARP inhibitor resistance

scientific article published on 24 May 2019

Claudin-4 SPECT Imaging Allows Detection of Aplastic Lesions in a Mouse Model of Breast Cancer.

scientific article

Combination Strategies to Improve Targeted Radionuclide Therapy

scientific article published on 09 October 2020

Comparative biodistribution study of the new tumor tracer [123I]-2-iodo-L-phenylalanine with [123I]-2-iodo-L-tyrosine

scientific article published on January 2006

Comparison between 1 T MRI and non-MRI based volumetry in inoculated tumours in mice.

scientific article

DNA double-strand break repair: a theoretical framework and its application.

scientific article published on 27 January 2016

Development of a T-cell Receptor Mimic Antibody against Wild-Type p53 for Cancer Immunotherapy

scientific article published on 31 March 2017

Development of an enzymatic pretargeting strategy for dual-modality imaging

scientific article

Drug-resistant AML cells and primary AML specimens are killed by 111In-anti-CD33 monoclonal antibodies modified with nuclear localizing peptide sequences.

scientific article

Dual-isotope imaging allows in vivo immunohistochemistry using radiolabelled antibodies in tumours

scientific article published on 05 February 2019

Early Detection in a Mouse Model of Pancreatic Cancer by Imaging DNA Damage Response Signalling

scientific article published on 20 December 2019

ErbB-2 blockade and prenyltransferase inhibition alter epidermal growth factor and epidermal growth factor receptor trafficking and enhance (111)In-DTPA-hEGF Auger electron radiation therapy.

scientific article published on 15 April 2011

Hypoxia imaging using PET and SPECT: the effects of anesthetic and carrier gas on [Cu]-ATSM, [Tc]-HL91 and [F]-FMISO tumor hypoxia accumulation

scientific article

Imaging DNA Damage Repair in vivo Following 177Lu-DOTATATE Therapy

scientific article published on 22 November 2019

Imaging DNA damage allows detection of preneoplasia in the BALB-neuT model of breast cancer.

scientific article published on 13 November 2014

Imaging DNA damage in vivo using gammaH2AX-targeted immunoconjugates

scientific article

Imaging of Claudin-4 in Pancreatic Ductal Adenocarcinoma Using a Radiolabelled Anti-Claudin-4 Monoclonal Antibody

scientific article published on 25 August 2017

Imaging the DNA damage response with PET and SPECT

scientific article

Imaging the inside of a tumour: a review of radionuclide imaging and theranostics targeting intracellular epitopes

scientific article published on 07 January 2014

In Vivo Pretargeted Imaging of HER2 and TAG-72 Expression Using the HaloTag Enzyme.

scientific article

In vitro and in vivo evaluation of [123I]-VEGF165 as a potential tumor marker

scientific article published on July 2005

In vitro and in vivo targeting properties of iodine-123- or iodine-131-labeled monoclonal antibody 14C5 in a non-small cell lung cancer and colon carcinoma model.

scientific article

In vivo apoptosis detection with radioiodinated Annexin V in LoVo tumour-bearing mice following Tipifarnib (Zarnestra, R115777) farnesyltransferase inhibitor therapy.

scientific article

Influence of farnesyl transferase inhibitor treatment on epidermal growth factor receptor status.

scientific article published on August 2004

Manual and automated Cu-mediated radiosynthesis of the PARP inhibitor [18F]olaparib

scientific article published on 28 February 2020

Micro-CT for anatomic referencing in PET and SPECT: radiation dose, biologic damage, and image quality

scientific article published on 07 October 2011

Monitoring response to anti-angiogenic mTOR inhibitor therapy in vivo using 111In-bevacizumab

scientific article

Optimization by experimental design of precursor synthesis and radiolabeling of 2-iodo-L-phenylalanine, a novel amino acid for tumor imaging

scientific article published in June 2006

PET and SPECT Imaging for the Acceleration of Anti-Cancer Drug Development.

scientific article published on 22 April 2015

PET imaging of DNA damage using (89)Zr-labelled anti-γH2AX-TAT immunoconjugates

scientific article published on 2 June 2015

PET imaging of PARP expression using [F]olaparib ⬇️

scientific article published on 02 November 2018

Phase I trial to evaluate the tumor and normal tissue uptake, radiation dosimetry and safety of (111)In-DTPA-human epidermal growth factor in patients with metastatic EGFR-positive breast cancer

scientific article

Pre-labelling versus direct labelling of anthrax proteins for imaging of matrix metalloproteinases activity using DOTA-GA

scientific article published on 01 May 2019

Probing the limits of Q-tag bioconjugation of antibodies

scientific article published on 01 September 2019

Properties of [(111)In]-labeled HIV-1 tat peptide radioimmunoconjugates in tumor-bearing mice following intravenous or intratumoral injection.

scientific article published on January 2008

Radioiodinated recombinant human TSH: a novel radiopharmaceutical for thyroid cancer metastases detection.

scientific article published on February 2004

Scaling-down antibody radiolabeling reactions with zirconium-89.

scientific article

Selective permeabilization of the blood-brain barrier at sites of metastasis

scientific article published on 09 October 2013

Small animal positron emission tomography during vagus nerve stimulation in rats: a pilot study

scientific article

Subcutaneous tumor volume measurement in the awake, manually restrained mouse using MRI.

scientific article

Synthesis and assessment of [11C]acetylhomotaurine as an imaging agent for the study of the pharmacodynamic properties of acamprosate by positron emission tomography

scientific article

Synthesis, biodistribution and effects of farnesyltransferase inhibitor therapy on tumour uptake in mice of 99mTc labelled epidermal growth factor.

scientific article

Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation.

scientific article published on 6 December 2012

Targeting the Nucleus: An Overview of Auger-Electron Radionuclide Therapy ⬇️

scientific article published on December 1, 2010

Targeting the Tumour: Cell Penetrating Peptides for Molecular Imaging and Radiotherapy.

scientific article

The level of insulin growth factor-1 receptor expression is directly correlated with the tumor uptake of (111)In-IGF-1(E3R) in vivo and the clonogenic survival of breast cancer cells exposed in vitro to trastuzumab (Herceptin).

scientific article

Tumor Imaging Using Radiolabeled Matrix Metalloproteinase-Activated Anthrax Proteins

scientific article published on 06 April 2019

Use of [123I]-2-iodo-L-phenylalanine as a tumor imaging agent in two dogs with synovial cell sarcoma.

scientific article published in September 2007

Valine-based biphenylsulphonamide matrix metalloproteinase inhibitors as tumor imaging agents

scientific article published on 20 March 2006

[18F]AZD2461, an Insight on Difference in PARP Binding Profiles for DNA Damage Response PET Imaging

scientific article published on 27 April 2020

List of works by Bart Cornelissen

111In-BnDTPA-F3: an Auger electron-emitting radiotherapeutic agent that targets nucleolin

123/125I-labelled 2-iodo-L: -phenylalanine and 2-iodo-D: -phenylalanine: comparative uptake in various tumour types and biodistribution in mice.

18F-Trifluoromethanesulfinate Enables Direct C-H 18F-Trifluoromethylation of Native Aromatic Residues in Peptides

A Carbon-Fiber Sheet Resistor for MR-, CT-, SPECT-, and PET-Compatible Temperature Maintenance in Small Animals

A comparison of the behavior of (64)Cu-acetate and (64)Cu-ATSM in vitro and in vivo

A dual radiolabelling approach for tracking metal complexes: investigating the speciation of copper bis(thiosemicarbazonates) in vitro and in vivo

Amplification of DNA damage by a γH2AX-targeted radiopharmaceutical.

Associations between the uptake of 111In-DTPA-trastuzumab, HER2 density and response to trastuzumab (Herceptin) in athymic mice bearing subcutaneous human tumour xenografts.

Bioorthogonal chemistry: implications for pretargeted nuclear (PET/SPECT) imaging and therapy

Call to arms: need for radiobiology in molecular radionuclide therapy

Can γH2AX be used to personalise cancer treatment?

Cell penetrating peptides for in vivo molecular imaging applications.

Chlorambucil targets BRCA1/2-deficient tumours and counteracts PARP inhibitor resistance

Claudin-4 SPECT Imaging Allows Detection of Aplastic Lesions in a Mouse Model of Breast Cancer.

Combination Strategies to Improve Targeted Radionuclide Therapy

Comparative biodistribution study of the new tumor tracer [123I]-2-iodo-L-phenylalanine with [123I]-2-iodo-L-tyrosine

Comparison between 1 T MRI and non-MRI based volumetry in inoculated tumours in mice.

DNA double-strand break repair: a theoretical framework and its application.

Development of a T-cell Receptor Mimic Antibody against Wild-Type p53 for Cancer Immunotherapy

Development of an enzymatic pretargeting strategy for dual-modality imaging

Drug-resistant AML cells and primary AML specimens are killed by 111In-anti-CD33 monoclonal antibodies modified with nuclear localizing peptide sequences.

Dual-isotope imaging allows in vivo immunohistochemistry using radiolabelled antibodies in tumours

Early Detection in a Mouse Model of Pancreatic Cancer by Imaging DNA Damage Response Signalling

ErbB-2 blockade and prenyltransferase inhibition alter epidermal growth factor and epidermal growth factor receptor trafficking and enhance (111)In-DTPA-hEGF Auger electron radiation therapy.

Hypoxia imaging using PET and SPECT: the effects of anesthetic and carrier gas on [Cu]-ATSM, [Tc]-HL91 and [F]-FMISO tumor hypoxia accumulation

Imaging DNA Damage Repair in vivo Following 177Lu-DOTATATE Therapy

Imaging DNA damage allows detection of preneoplasia in the BALB-neuT model of breast cancer.

Imaging DNA damage in vivo using gammaH2AX-targeted immunoconjugates

Imaging of Claudin-4 in Pancreatic Ductal Adenocarcinoma Using a Radiolabelled Anti-Claudin-4 Monoclonal Antibody

Imaging the DNA damage response with PET and SPECT

Imaging the inside of a tumour: a review of radionuclide imaging and theranostics targeting intracellular epitopes

In Vivo Pretargeted Imaging of HER2 and TAG-72 Expression Using the HaloTag Enzyme.

In vitro and in vivo evaluation of [123I]-VEGF165 as a potential tumor marker

In vitro and in vivo targeting properties of iodine-123- or iodine-131-labeled monoclonal antibody 14C5 in a non-small cell lung cancer and colon carcinoma model.

In vivo apoptosis detection with radioiodinated Annexin V in LoVo tumour-bearing mice following Tipifarnib (Zarnestra, R115777) farnesyltransferase inhibitor therapy.

Influence of farnesyl transferase inhibitor treatment on epidermal growth factor receptor status.

Manual and automated Cu-mediated radiosynthesis of the PARP inhibitor [18F]olaparib

Micro-CT for anatomic referencing in PET and SPECT: radiation dose, biologic damage, and image quality

Monitoring response to anti-angiogenic mTOR inhibitor therapy in vivo using 111In-bevacizumab

Optimization by experimental design of precursor synthesis and radiolabeling of 2-iodo-L-phenylalanine, a novel amino acid for tumor imaging

PET and SPECT Imaging for the Acceleration of Anti-Cancer Drug Development.

PET imaging of DNA damage using (89)Zr-labelled anti-γH2AX-TAT immunoconjugates

PET imaging of PARP expression using [F]olaparib ⬇️

Phase I trial to evaluate the tumor and normal tissue uptake, radiation dosimetry and safety of (111)In-DTPA-human epidermal growth factor in patients with metastatic EGFR-positive breast cancer

Pre-labelling versus direct labelling of anthrax proteins for imaging of matrix metalloproteinases activity using DOTA-GA

Probing the limits of Q-tag bioconjugation of antibodies

Properties of [(111)In]-labeled HIV-1 tat peptide radioimmunoconjugates in tumor-bearing mice following intravenous or intratumoral injection.

Radioiodinated recombinant human TSH: a novel radiopharmaceutical for thyroid cancer metastases detection.

Scaling-down antibody radiolabeling reactions with zirconium-89.

Selective permeabilization of the blood-brain barrier at sites of metastasis

Small animal positron emission tomography during vagus nerve stimulation in rats: a pilot study

Subcutaneous tumor volume measurement in the awake, manually restrained mouse using MRI.

Synthesis and assessment of [11C]acetylhomotaurine as an imaging agent for the study of the pharmacodynamic properties of acamprosate by positron emission tomography

Synthesis, biodistribution and effects of farnesyltransferase inhibitor therapy on tumour uptake in mice of 99mTc labelled epidermal growth factor.

Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation.

Targeting the Nucleus: An Overview of Auger-Electron Radionuclide Therapy ⬇️

Targeting the Tumour: Cell Penetrating Peptides for Molecular Imaging and Radiotherapy.

The level of insulin growth factor-1 receptor expression is directly correlated with the tumor uptake of (111)In-IGF-1(E3R) in vivo and the clonogenic survival of breast cancer cells exposed in vitro to trastuzumab (Herceptin).

Tumor Imaging Using Radiolabeled Matrix Metalloproteinase-Activated Anthrax Proteins

Use of [123I]-2-iodo-L-phenylalanine as a tumor imaging agent in two dogs with synovial cell sarcoma.

Valine-based biphenylsulphonamide matrix metalloproteinase inhibitors as tumor imaging agents

[18F]AZD2461, an Insight on Difference in PARP Binding Profiles for DNA Damage Response PET Imaging