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List of works by David Sancho

Aggregation of MHC class I molecules on a CD8+ alphabeta T cell clone specifically inhibits non-antigen-specific lysis of target cells

scientific article published in January 2004

Antigen Cross-Presentation and T-Cell Cross-Priming In Cancer Immunology And Immunotherapy

scientific article published on September 2017

Batf3-dependent CD103+ dendritic cells are major producers of IL-12 that drive local Th1 immunity against Leishmania major infection in mice

scientific article published on 28 November 2014

CD69 is an immunoregulatory molecule induced following activation

scientific article

CD69 targeting differentially affects the course of collagen-induced arthritis

scholarly article by David Sancho et al published December 2006 in Journal of Leukocyte Biology

CLEC-2 signaling via Syk in myeloid cells can regulate inflammatory responses

scientific article published on 17 August 2011

Cancer Immunotherapy with Immunomodulatory Anti-CD137 and Anti-PD-1 Monoclonal Antibodies Requires BATF3-Dependent Dendritic Cells

scientific article published on 22 October 2015

Cell adhesion and polarity during immune interactions

scientific article

Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells

scientific article

Critical role for Sec22b-dependent antigen cross-presentation in antitumor immunity

scientific article

Cutting Edge: Dynamic Redistribution of Tetraspanin CD81 at the Central Zone of the Immune Synapse in Both T Lymphocytes and APC

DNGR-1 in dendritic cells limits tissue damage by dampening neutrophil recruitment

scientific article published in Science

DNGR-1 is a specific and universal marker of mouse and human Batf3-dependent dendritic cells in lymphoid and nonlymphoid tissues

scientific article

DNGR-1(+) dendritic cells are located in meningeal membrane and choroid plexus of the noninjured brain

scientific article published on 17 July 2015

Dectin-1/2-induced autocrine PGE2 signaling licenses dendritic cells to prime Th2 responses

scientific article published on 18 April 2018

Dendritic cells in cancer immunology and immunotherapy

scientific article published on 29 August 2019

Distinct Compartmentalization of the Chemokines CXCL1 and CXCL2 and the Atypical Receptor ACKR1 Determine Discrete Stages of Neutrophil Diapedesis

scholarly article by Tamara Girbl et al published 18 December 2018 in Immunity

Effective cancer immunotherapy by natural mouse conventional type-1 dendritic cells bearing dead tumor antigen

scholarly article by Stefanie K Wculek et al published 8 April 2019 in Journal for Immunotherapy of Cancer

Efficient and versatile manipulation of the peripheral CD4+ T-cell compartment by antigen targeting to DNGR-1/CLEC9A.

scientific article

Enhanced anti-tumour immunity requires the interplay between resident and circulating memory CD8+ T cells

scientific article

Enhanced antitumor immunity in mice deficient in CD69.

scientific article

F-Actin Is an Evolutionarily Conserved Damage-Associated Molecular Pattern Recognized by DNGR-1, a Receptor for Dead Cells

Fgr kinase is required for proinflammatory macrophage activation during diet-induced obesity

scientific article published on 17 September 2020

Flexible Signaling of Myeloid C-Type Lectin Receptors in Immunity and Inflammation

scientific article

Flow Cytometry Data Preparation Guidelines for Improved Automated Phenotypic Analysis

Functional CD169 on Macrophages Mediates Interaction with Dendritic Cells for CD8+ T Cell Cross-Priming

scientific article published in February 2018

Functional analysis of ligand-binding and signal transduction domains of CD69 and CD23 C-type lectin leukocyte receptors

scientific journal article

Genealogy, Dendritic Cell Priming, and Differentiation of Tissue-Resident Memory CD8 T Cells

HDAC6 deacetylase activity links the tubulin cytoskeleton with immune synapse organization

scientific article published on April 2004

Human Dendritic Cell Subsets Undergo Distinct Metabolic Reprogramming for Immune Response

Human dendritic cells activated with MV130 induce Th1, Th17 and IL-10 responses via RIPK2 and MyD88 signalling pathways

scientific article published on 11 August 2017

Identification of a dendritic cell receptor that couples sensing of necrosis to immunity

scientific article published on April 2009

Innate Immune Function of Mitochondrial Metabolism

scientific article published on 8 May 2017

Interferon-β production via Dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. albicans

scientific article published on 13 June 2013

Interleukin-15 and interferon-gamma participate in the cross-talk between natural killer and monocytic cells required for tumour necrosis factor production

scientific article published on January 2006

Intratumoral immunotherapy with XCL1 and sFlt3L encoded in recombinant Semliki Forest Virus-derived vectors fosters dendritic cell-mediated T cell cross-priming

Leishmania Hijacks Myeloid Cells for Immune Escape

scientific article

Leishmania Uses Mincle to Target an Inhibitory ITAM Signaling Pathway in Dendritic Cells that Dampens Adaptive Immunity to Infection

scientific article

Lipid rafts mediate biosynthetic transport to the T lymphocyte uropod subdomain and are necessary for uropod integrity and function

scientific article published in February 2002

Lung CD103+ dendritic cells restrain allergic airway inflammation through IL-12 production

scientific article published on 18 May 2017

Metabolism of tissue macrophages in homeostasis and pathology

scientific article published in 2021

Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity

scholarly article by María Martínez-López et al published 19 February 2019 in Immunity

Myeloid C-type lectins in innate immunity

scientific article published on December 2006

Optimal Generation of Tissue-Resident but Not Circulating Memory T Cells during Viral Infection Requires Crosspriming by DNGR-1+ Dendritic Cells

scientific article

P-selectin glycoprotein ligand-1 modulates immune inflammatory responses in the enteric lamina propria

scientific article published on 22 March 2011

Rapamycin attenuates atherosclerosis induced by dietary cholesterol in apolipoprotein-deficient mice through a p27 Kip1 -independent pathway

scientific article

Rational design of adjuvants targeting the C-type lectin Mincle

scientific article published on 21 February 2017

Regulation of microtubule-organizing center orientation and actomyosin cytoskeleton rearrangement during immune interactions

scientific article

Role of Fyn in the rearrangement of tubulin cytoskeleton induced through TCR.

scientific article published on April 2006

Role of ICAM-3 in the initial interaction of T lymphocytes and APCs

article published in 2002

SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1-Nrf2

scientific article published on 16 September 2019

SHIP-1 Couples to the Dectin-1 hemITAM and Selectively Modulates Reactive Oxygen Species Production in Dendritic Cells in Response to Candida albicans

scientific article

Selective inactivation of p27(Kip1) in hematopoietic progenitor cells increases neointimal macrophage proliferation and accelerates atherosclerosis

scientific article published on 22 September 2003

Sensing of cell death by myeloid C-type lectin receptors

scientific article

Signaling by myeloid C-type lectin receptors in immunity and homeostasis

scientific article published on 6 January 2012

Signalling versatility following self and non-self sensing by myeloid C-type lectin receptors

scientific article published on 16 September 2014

Spanish Immunology on the move

scientific article published in June 2015

Structure of the Complex of F-Actin and DNGR-1, a C-Type Lectin Receptor Involved in Dendritic Cell Cross-Presentation of Dead Cell-Associated Antigens

scientific article published on 12 May 2015

TCR engagement induces proline-rich tyrosine kinase-2 (Pyk2) translocation to the T cell-APC interface independently of Pyk2 activity and in an immunoreceptor tyrosine-based activation motif-mediated fashion

scientific article published on July 2002

The DC receptor DNGR-1 mediates cross-priming of CTLs during vaccinia virus infection in mice

scientific article published on 16 April 2012

The RhoA effector mDia is induced during T cell activation and regulates actin polymerization and cell migration in T lymphocytes

scientific article (publication date: 15 July 2003)

The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected mice

scientific article published on 16 April 2012

The role of CD69 in acute neutrophil-mediated inflammation

scientific article

The tyrosine kinase PYK-2/RAFTK regulates natural killer (NK) cell cytotoxic response, and is translocated and activated upon specific target cell recognition and killing

scientific article

The use of transgenic mice for the production of a human monoclonal antibody specific for human CD69 antigen

scientific article published on November 2003

Therapeutic effect of all-trans-retinoic acid (at-RA) on an autoimmune nephritis experimental model: role of the VLA-4 integrin

scientific article published on 24 January 2007

Trained Immunity-Based Vaccines: A New Paradigm for the Development of Broad-Spectrum Anti-infectious Formulations

article

Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin

scientific article

U5A2-13, an antigen originally found on mouse NK-like T cells, is an early inducible cell surface antigen during lymphoid activation

scientific article published on January 1, 2003

Von Hippel-Lindau Protein Is Required for Optimal Alveolar Macrophage Terminal Differentiation, Self-Renewal, and Function

article published in 2018