List of works - Lucía García-Ortega

A non-cytotoxic but ribonucleolytically specific ribotoxin variant: implication of tryptophan residues in the cytotoxicity of hirsutellin A.

scientific article published on May 2012

Anomalous electrophoretic behavior of a very acidic protein: ribonuclease U2.

scientific article published in September 2005

Binding and enzymatic properties of Ageritin, a fungal ribotoxin with novel zinc-dependent function

scientific article published on 18 June 2019

Characterization of a new toxin from the entomopathogenic fungus Metarhizium anisopliae: the ribotoxin anisoplin

scientific article published on 29 July 2016

Cleavage of the sarcin-ricin loop of 23S rRNA differentially affects EF-G and EF-Tu binding

scientific article

Conserved asparagine residue 54 of alpha-sarcin plays a role in protein stability and enzyme activity

scientific article published in December 2004

Deletion of the NH2-terminal beta-hairpin of the ribotoxin alpha-sarcin produces a nontoxic but active ribonuclease.

scientific article

Fungal Ribotoxins: A Review of Potential Biotechnological Applications.

scientific article published on 21 February 2017

Fungal extracellular ribotoxins as insecticidal agents

scientific article

Fungal ribotoxins: Natural protein-based weapons against insects

scientific article published on 14 March 2014

Hirsutellin A: A Paradigmatic Example of the Insecticidal Function of Fungal Ribotoxins.

scientific article published on 09 July 2013

Implication of an Asp residue in the ribonucleolytic activity of hirsutellin A reveals new electrostatic interactions at the active site of ribotoxins

scientific article published on 24 August 2011

Influence of key residues on the heterologous extracellular production of fungal ribonuclease U2 in the yeast Pichia pastoris

scientific article

Involvement of loop 5 lysine residues and the N-terminal β-hairpin of the ribotoxin hirsutellin A on its insecticidal activity.

scientific article published on 19 November 2015

Involvement of loops 2 and 3 of α-sarcin on its ribotoxic activity.

scientific article published on 15 January 2015

Involvement of the amino-terminal beta-hairpin of the Aspergillus ribotoxins on the interaction with membranes and nonspecific ribonuclease activity.

scientific article published on August 2001

Leucine 145 of the ribotoxin alpha-sarcin plays a key role for determining the specificity of the ribosome-inactivating activity of the protein.

scientific article published on January 2003

Minimized natural versions of fungal ribotoxins show improved active site plasticity.

scientific article published on 7 March 2017

Modeling the highly specific ribotoxin recognition of ribosomes

scientific article published on 01 December 2005

NMR structure of the noncytotoxic alpha-sarcin mutant Delta(7-22): the importance of the native conformation of peripheral loops for activity.

scientific article published in April 2004

Precise alignment of peptidyl tRNA by the decoding center is essential for EF-G-dependent translocation

scientific article published in October 2008

Production and characterization of a noncytotoxic deletion variant of the Aspergillus fumigatus allergen Aspf1 displaying reduced IgE binding.

scientific article

Production and characterization of scFvA33T1, an immunoRNase targeting colon cancer cells

scientific article published on 25 July 2012

RNase U2 and alpha-sarcin: a study of relationships

scientific article published on 01 January 2001

Ribonuclease U2: cloning, production inPichia pastorisand affinity chromatography purification of the active recombinant protein

scientific article published on 01 August 2000

Structural and enzymatic properties of Ageritin, a novel metal-dependent ribotoxin-like protein with antitumor activity

scientific article published on 18 September 2018

The acidic ribosomal stalk proteins are not required for the highly specific inactivation exerted by α-sarcin of the eukaryotic ribosome.

scientific article published on 4 March 2014

The behavior of sea anemone actinoporins at the water-membrane interface

scientific article published on 20 May 2011

The ribonucleolytic activity of the ribotoxin α-sarcin is not essential for in vitro protein biosynthesis inhibition

scientific article published on 13 July 2011

The solubility of the ribotoxin alpha-sarcin, produced as a recombinant protein in Escherichia coli, is increased in the presence of thioredoxin

scientific article published on 01 April 2000

List of works by Lucía García-Ortega

A non-cytotoxic but ribonucleolytically specific ribotoxin variant: implication of tryptophan residues in the cytotoxicity of hirsutellin A.

Anomalous electrophoretic behavior of a very acidic protein: ribonuclease U2.

Binding and enzymatic properties of Ageritin, a fungal ribotoxin with novel zinc-dependent function

Characterization of a new toxin from the entomopathogenic fungus Metarhizium anisopliae: the ribotoxin anisoplin

Cleavage of the sarcin-ricin loop of 23S rRNA differentially affects EF-G and EF-Tu binding

Conserved asparagine residue 54 of alpha-sarcin plays a role in protein stability and enzyme activity

Deletion of the NH2-terminal beta-hairpin of the ribotoxin alpha-sarcin produces a nontoxic but active ribonuclease.

Fungal Ribotoxins: A Review of Potential Biotechnological Applications.

Fungal extracellular ribotoxins as insecticidal agents

Fungal ribotoxins: Natural protein-based weapons against insects

Hirsutellin A: A Paradigmatic Example of the Insecticidal Function of Fungal Ribotoxins.

Implication of an Asp residue in the ribonucleolytic activity of hirsutellin A reveals new electrostatic interactions at the active site of ribotoxins

Influence of key residues on the heterologous extracellular production of fungal ribonuclease U2 in the yeast Pichia pastoris

Involvement of loop 5 lysine residues and the N-terminal β-hairpin of the ribotoxin hirsutellin A on its insecticidal activity.

Involvement of loops 2 and 3 of α-sarcin on its ribotoxic activity.

Involvement of the amino-terminal beta-hairpin of the Aspergillus ribotoxins on the interaction with membranes and nonspecific ribonuclease activity.

Leucine 145 of the ribotoxin alpha-sarcin plays a key role for determining the specificity of the ribosome-inactivating activity of the protein.

Minimized natural versions of fungal ribotoxins show improved active site plasticity.

Modeling the highly specific ribotoxin recognition of ribosomes

NMR structure of the noncytotoxic alpha-sarcin mutant Delta(7-22): the importance of the native conformation of peripheral loops for activity.

Precise alignment of peptidyl tRNA by the decoding center is essential for EF-G-dependent translocation

Production and characterization of a noncytotoxic deletion variant of the Aspergillus fumigatus allergen Aspf1 displaying reduced IgE binding.

Production and characterization of scFvA33T1, an immunoRNase targeting colon cancer cells

RNase U2 and alpha-sarcin: a study of relationships

Ribonuclease U2: cloning, production inPichia pastorisand affinity chromatography purification of the active recombinant protein

Structural and enzymatic properties of Ageritin, a novel metal-dependent ribotoxin-like protein with antitumor activity

The acidic ribosomal stalk proteins are not required for the highly specific inactivation exerted by α-sarcin of the eukaryotic ribosome.

The behavior of sea anemone actinoporins at the water-membrane interface

The ribonucleolytic activity of the ribotoxin α-sarcin is not essential for in vitro protein biosynthesis inhibition

The solubility of the ribotoxin alpha-sarcin, produced as a recombinant protein in Escherichia coli, is increased in the presence of thioredoxin