List of works - Joseph Quinn

18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery

scientific article published in February 2018

A copper-lowering strategy attenuates amyloid pathology in a transgenic mouse model of Alzheimer's disease.

scientific article

A randomized placebo-controlled pilot trial of omega-3 fatty acids and alpha lipoic acid in Alzheimer's disease

scientific article published on January 2014

A translational continuum of model systems for evaluating treatment strategies in Alzheimer's disease: isradipine as a candidate drug.

scientific article

ADAM10 expression and promoter haplotype in Alzheimer's disease

scientific article

APOE ε4 increases risk for dementia in pure synucleinopathies

scientific article published on February 2013

APOE, MAPT, and SNCA genes and cognitive performance in Parkinson disease

scientific article

Aberrant detergent-insoluble excitatory amino acid transporter 2 accumulates in Alzheimer disease.

scientific article

Age and apolipoprotein E*4 allele effects on cerebrospinal fluid beta-amyloid 42 in adults with normal cognition

scientific article published in July 2006

Alterations in mitochondrial number and function in Alzheimer's disease fibroblasts

scientific article published on 12 April 2015

An aberrant protein complex in CSF as a biomarker of Alzheimer disease

scientific article published on 30 April 2008

An anatomical study of cholinergic innervation in rat cerebral cortex

scientific article published on May 1988

Analysis of extracellular RNA in cerebrospinal fluid

scientific article

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Application of targeted quantitative proteomics analysis in human cerebrospinal fluid using a liquid chromatography matrix-assisted laser desorption/ionization time-of-flight tandem mass spectrometer (LC MALDI TOF/TOF) platform

scientific article

Ascorbic acid and rates of cognitive decline in Alzheimer's disease.

scientific article published on January 2009

Association of cerebrospinal fluid Aβ42 with A2M gene in cognitively normal subjects

scientific article published on 04 September 2013

Association of cognitive domains with postural instability/gait disturbance in Parkinson's disease.

scientific article published on 14 April 2015

Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans

scientific article published on 16 February 2012

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Beta-amyloid plaques induce neuritic dystrophy of nitric oxide-producing neurons in a transgenic mouse model of Alzheimer's disease

scientific article published in April 2001

Biomarkers for Alzheimer's disease: showing the way or leading us astray?

scientific article published on January 2013

Blood-brain barrier impairment in Alzheimer disease: stability and functional significance

scientific article published on May 2007

Brain volume loss in MCI predicts dementia.

scientific article published in January 2006

CCR6: a biomarker for Alzheimer's-like disease in a triple transgenic mouse model

scientific article

CSF Aβ(42) and tau in Parkinson's disease with cognitive impairment.

scientific article

Caffeoylquinic acids in Centella asiatica protect against amyloid-β toxicity.

scientific article published on January 2014

Calcium channel blocking as a therapeutic strategy for Alzheimer's disease: The case for isradipine ⬇️

scientific article published on September 8, 2011

Centella asiatica Attenuates Amyloid-β-Induced Oxidative Stress and Mitochondrial Dysfunction

scientific article published on January 2015

Centella asiatica Extract Improves Behavioral Deficits in a Mouse Model of Alzheimer's Disease: Investigation of a Possible Mechanism of Action.

scientific article published on 15 February 2012

Centella asiatica modulates antioxidant and mitochondrial pathways and improves cognitive function in mice

scientific article published on 16 January 2016

Centella asiatica water extract shows low potential for CYP-mediated drug interactions

scientific article published on 24 June 2020

Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression

scientific article

Cerebrospinal fluid biomarkers in mild cognitive impairment and dementia

scientific article

Cerebrospinal fluid peptides as potential Parkinson disease biomarkers: a staged pipeline for discovery and validation.

scientific article

Cerebrospinal fluid tau and beta-amyloid: how well do these biomarkers reflect autopsy-confirmed dementia diagnoses?

scientific article published in December 2003

Chronic dietary alpha-lipoic acid reduces deficits in hippocampal memory of aged Tg2576 mice

scientific article published on 31 January 2006

Chronic melatonin therapy fails to alter amyloid burden or oxidative damage in old Tg2576 mice: implications for clinical trials

scientific article

Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins

scientific article

Comment: Gene-environment interactions in dementia—

article

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

scientific article

Common variation in the LRRK2 gene is a risk factor for Parkinson's disease

scientific article

Complement 3 and factor h in human cerebrospinal fluid in Parkinson's disease, Alzheimer's disease, and multiple-system atrophy

scientific article

Copper in Alzheimer's disease: too much or too little?

scientific article published on May 2009

Cross-sectional and longitudinal relationships between cerebrospinal fluid biomarkers and cognitive function in people without cognitive impairment from across the adult life span

scientific article

Detecting Alzheimer disease before it happens: The key to prevention?

scientific article published in July 2008

Diagnostic Values of Cerebrospinal Fluid T-Tau and Aβ₄₂ using Meso Scale Discovery Assays for Alzheimer's Disease

scientific article

Docosahexaenoic acid supplementation and cognitive decline in Alzheimer disease: a randomized trial

scientific article

Dyslipidemia and blood-brain barrier integrity in Alzheimer's disease

scientific article

Effects of a gamma-secretase inhibitor in a randomized study of patients with Alzheimer disease

scientific article published in February 2006

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

scientific article

Evaluation of mild cognitive impairment subtypes in Parkinson's disease.

scientific article

F(2)-isoprostanes as biomarkers of late-onset Alzheimer's disease.

scientific article published on September 2007

F2-isoprostanes in Alzheimer and other neurodegenerative diseases

scientific article

Failure of biomarkers in clinical trials of Alzheimer's disease: blaming the messenger?

scientific article published on January 2009

GBA Variants are associated with a distinct pattern of cognitive deficits in Parkinson's disease

scientific article

Gastrointestinal Motility and Response to Levodopa in Parkinson's Disease: A Proof‐of‐Concept Study

scientific article published in 2022

Gender Effects on Plasma and Brain Copper ⬇️

scientific article published on October 19, 2011

Gene expression profiles of transcripts in amyloid precursor protein transgenic mice: up-regulation of mitochondrial metabolism and apoptotic genes is an early cellular change in Alzheimer's disease.

scientific article published on 28 April 2004

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Identification and validation of novel cerebrospinal fluid biomarkers for staging early Alzheimer's disease

scientific article (publication date: 12 January 2011)

Identification of Glycoproteins in Human Cerebrospinal Fluid with a Complementary Proteomic Approach

scientific article published on 01 October 2006

Incidence of New-Onset Seizures in Mild to Moderate Alzheimer Disease ⬇️

scientific article published on March 1, 2012

Increased CSF E-Selectin in Clinical Alzheimer's Disease without Altered CSF Aβ42 and Tau.

scientific article published in August 2015

Increased cerebrospinal fluid F2-isoprostanes are associated with aging and latent Alzheimer's disease as identified by biomarkers

scientific article published on 15 July 2010

Inflammation and cerebral amyloidosis are disconnected in an animal model of Alzheimer's disease

scientific article published in April 2003

Influence of lifestyle modifications on age-related free radical injury to brain

scientific article

Isoprostanes and related products of lipid peroxidation in neurodegenerative diseases.

scientific article published on March 2004

L-type voltage-gated calcium channel blockade with isradipine as a therapeutic strategy for Alzheimer's disease ⬇️

scientific article published on September 9, 2010

Lipid peroxidation in aging brain and Alzheimer's disease

scientific article

MRI substudy participation in Alzheimer disease (AD) clinical trials: baseline comparability of a substudy sample to entire study population

scientific article

Memory, mood, and vitamin D in persons with Parkinson's disease

scientific article published on January 2013

Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

scientific article published on 21 March 2006

Modeling of pathological traits in Alzheimer's disease based on systemic extracellular signaling proteome.

scientific article

Modulation of tau phosphorylation by environmental copper

scientific article

Mouse cerebral prostaglandins, but not oxidative damage, change with age and are responsive to indomethacin treatment

scientific article published in March 2002

Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease.

scientific article

Non-targeted lipidomics of CSF and frontal cortex grey and white matter in control, mild cognitive impairment, and Alzheimer's disease subjects

scientific article published on 10 April 2015

Novel antigenic determinant expressed in neurons of the dorsolateral hypothalamus in rat and human

scientific article published on April 1992

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

scientific article

Nutrient biomarker patterns, cognitive function, and MRI measures of brain aging.

scientific article published on 28 December 2011

Open label tissue plasminogen activator for stroke: The Oregon experience

article

Oral zinc reduces amyloid burden in Tg2576 mice

scientific article

People with Parkinson's disease and normal MMSE score have a broad range of cognitive performance

scientific article

Peripheral Blood NRF2 Expression as a Biomarker in Human Health and Disease

scientific article published on 30 December 2020

Peripheral F2-isoprostanes and F4-neuroprostanes are not increased in Alzheimer's disease

scientific article published in August 2002

Phytic Acid as a Potential Treatment for Alzheimer's Pathology: Evidence from Animal and in vitro Models ⬇️

scientific article published on January 1, 2011

Plasma exosomal α-synuclein is likely CNS-derived and increased in Parkinson's disease.

scientific article

Plasma omega-3 PUFA and white matter mediated executive decline in older adults

scientific article published on 16 December 2013

Posttraumatic stress disorder as a risk factor for obesity among male military veterans

scientific article published in December 2007

Precision Medicine: Clarity for the Complexity of Dementia.

scientific article published on 24 December 2015

Prevention of age-related spatial memory deficits in a transgenic mouse model of Alzheimer's disease by chronic Ginkgo biloba treatment

scientific article published in November 2003

Quantitative proteomic analysis of age-related changes in human cerebrospinal fluid

scientific article published in February 2005

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article

Rarity of the Alzheimer disease-protective APP A673T variant in the United States

scientific article

Reduced CSF PLTP activity in Alzheimer's disease and other neurologic diseases; PLTP induces ApoE secretion in primary human astrocytes in vitro

scientific article published in May 2005

Reliability and validity of food frequency questionnaire and nutrient biomarkers in elders with and without mild cognitive impairment

scientific article

Review of selected databases of longitudinal aging studies

scientific article

Role of soluble epoxide hydrolase in age-related vascular cognitive decline.

scientific article

SNCA variant associated with Parkinson disease and plasma alpha-synuclein level

scientific article

STX, a Novel Membrane Estrogen Receptor Ligand, Protects Against Amyloid-β Toxicity.

scientific article published on 03 February 2016

Safety and acceptability of the research lumbar puncture

scientific article published in October 2005

Serum vitamin d concentrations are associated with falling and cognitive function in older adults ⬇️

scientific article published on October 1, 2012

Sex differences in progression to mild cognitive impairment and dementia in Parkinson's disease

scientific article published on 9 February 2018

Significance and confounders of peripheral DJ-1 and alpha-synuclein in Parkinson's disease.

scientific article

Surgery is associated with ventricular enlargement as well as cognitive and functional decline

scientific article published on 20 November 2015

Targeted Lipidomics of Fontal Cortex and Plasma Diacylglycerols (DAG) in Mild Cognitive Impairment and Alzheimer's Disease: Validation of DAG Accumulation Early in the Pathophysiology of Alzheimer's Disease

scientific article published on September 2015

Targeted discovery and validation of plasma biomarkers of Parkinson's disease

scientific article

Tau phosphorylation pathway genes and cerebrospinal fluid tau levels in Alzheimer's disease

scientific article published on 27 August 2012

The ageing systemic milieu negatively regulates neurogenesis and cognitive function.

scientific article

The blood-brain barrier and microvascular water exchange in Alzheimer's disease.

scientific article

Visuospatial functioning is associated with sleep disturbance and hallucinations in nondemented patients with Parkinson's disease

scientific article published on 10 June 2019

YKL-40: a novel prognostic fluid biomarker for preclinical Alzheimer's disease

scientific article

apoE isoforms and measures of anxiety in probable AD patients and Apoe-/- mice

scientific article published in May 2005

List of works by Joseph Quinn

18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery

A copper-lowering strategy attenuates amyloid pathology in a transgenic mouse model of Alzheimer's disease.

A randomized placebo-controlled pilot trial of omega-3 fatty acids and alpha lipoic acid in Alzheimer's disease

A translational continuum of model systems for evaluating treatment strategies in Alzheimer's disease: isradipine as a candidate drug.

ADAM10 expression and promoter haplotype in Alzheimer's disease

APOE ε4 increases risk for dementia in pure synucleinopathies

APOE, MAPT, and SNCA genes and cognitive performance in Parkinson disease

Aberrant detergent-insoluble excitatory amino acid transporter 2 accumulates in Alzheimer disease.

Age and apolipoprotein E*4 allele effects on cerebrospinal fluid beta-amyloid 42 in adults with normal cognition

Alterations in mitochondrial number and function in Alzheimer's disease fibroblasts

An aberrant protein complex in CSF as a biomarker of Alzheimer disease

An anatomical study of cholinergic innervation in rat cerebral cortex

Analysis of extracellular RNA in cerebrospinal fluid

Analysis of shared heritability in common disorders of the brain

Application of targeted quantitative proteomics analysis in human cerebrospinal fluid using a liquid chromatography matrix-assisted laser desorption/ionization time-of-flight tandem mass spectrometer (LC MALDI TOF/TOF) platform

Ascorbic acid and rates of cognitive decline in Alzheimer's disease.

Association of cerebrospinal fluid Aβ42 with A2M gene in cognitively normal subjects

Association of cognitive domains with postural instability/gait disturbance in Parkinson's disease.

Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Beta-amyloid plaques induce neuritic dystrophy of nitric oxide-producing neurons in a transgenic mouse model of Alzheimer's disease

Biomarkers for Alzheimer's disease: showing the way or leading us astray?

Blood-brain barrier impairment in Alzheimer disease: stability and functional significance

Brain volume loss in MCI predicts dementia.

CCR6: a biomarker for Alzheimer's-like disease in a triple transgenic mouse model

CSF Aβ(42) and tau in Parkinson's disease with cognitive impairment.

Caffeoylquinic acids in Centella asiatica protect against amyloid-β toxicity.

Calcium channel blocking as a therapeutic strategy for Alzheimer's disease: The case for isradipine ⬇️

Centella asiatica Attenuates Amyloid-β-Induced Oxidative Stress and Mitochondrial Dysfunction

Centella asiatica Extract Improves Behavioral Deficits in a Mouse Model of Alzheimer's Disease: Investigation of a Possible Mechanism of Action.

Centella asiatica modulates antioxidant and mitochondrial pathways and improves cognitive function in mice

Centella asiatica water extract shows low potential for CYP-mediated drug interactions

Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression

Cerebrospinal fluid biomarkers in mild cognitive impairment and dementia

Cerebrospinal fluid peptides as potential Parkinson disease biomarkers: a staged pipeline for discovery and validation.

Cerebrospinal fluid tau and beta-amyloid: how well do these biomarkers reflect autopsy-confirmed dementia diagnoses?

Chronic dietary alpha-lipoic acid reduces deficits in hippocampal memory of aged Tg2576 mice

Chronic melatonin therapy fails to alter amyloid burden or oxidative damage in old Tg2576 mice: implications for clinical trials

Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins

Comment: Gene-environment interactions in dementia—

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

Common variation in the LRRK2 gene is a risk factor for Parkinson's disease

Complement 3 and factor h in human cerebrospinal fluid in Parkinson's disease, Alzheimer's disease, and multiple-system atrophy

Copper in Alzheimer's disease: too much or too little?

Cross-sectional and longitudinal relationships between cerebrospinal fluid biomarkers and cognitive function in people without cognitive impairment from across the adult life span

Detecting Alzheimer disease before it happens: The key to prevention?

Diagnostic Values of Cerebrospinal Fluid T-Tau and Aβ₄₂ using Meso Scale Discovery Assays for Alzheimer's Disease

Docosahexaenoic acid supplementation and cognitive decline in Alzheimer disease: a randomized trial

Dyslipidemia and blood-brain barrier integrity in Alzheimer's disease

Effects of a gamma-secretase inhibitor in a randomized study of patients with Alzheimer disease

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

Evaluation of mild cognitive impairment subtypes in Parkinson's disease.

F(2)-isoprostanes as biomarkers of late-onset Alzheimer's disease.

F2-isoprostanes in Alzheimer and other neurodegenerative diseases

Failure of biomarkers in clinical trials of Alzheimer's disease: blaming the messenger?

GBA Variants are associated with a distinct pattern of cognitive deficits in Parkinson's disease

Gastrointestinal Motility and Response to Levodopa in Parkinson's Disease: A Proof‐of‐Concept Study

Gender Effects on Plasma and Brain Copper ⬇️

Gene expression profiles of transcripts in amyloid precursor protein transgenic mice: up-regulation of mitochondrial metabolism and apoptotic genes is an early cellular change in Alzheimer's disease.

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Identification and validation of novel cerebrospinal fluid biomarkers for staging early Alzheimer's disease

Identification of Glycoproteins in Human Cerebrospinal Fluid with a Complementary Proteomic Approach

Incidence of New-Onset Seizures in Mild to Moderate Alzheimer Disease ⬇️

Increased CSF E-Selectin in Clinical Alzheimer's Disease without Altered CSF Aβ42 and Tau.

Increased cerebrospinal fluid F2-isoprostanes are associated with aging and latent Alzheimer's disease as identified by biomarkers

Inflammation and cerebral amyloidosis are disconnected in an animal model of Alzheimer's disease

Influence of lifestyle modifications on age-related free radical injury to brain

Isoprostanes and related products of lipid peroxidation in neurodegenerative diseases.

L-type voltage-gated calcium channel blockade with isradipine as a therapeutic strategy for Alzheimer's disease ⬇️

Lipid peroxidation in aging brain and Alzheimer's disease

MRI substudy participation in Alzheimer disease (AD) clinical trials: baseline comparability of a substudy sample to entire study population

Memory, mood, and vitamin D in persons with Parkinson's disease

Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

Modeling of pathological traits in Alzheimer's disease based on systemic extracellular signaling proteome.

Modulation of tau phosphorylation by environmental copper

Mouse cerebral prostaglandins, but not oxidative damage, change with age and are responsive to indomethacin treatment

Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease.

Non-targeted lipidomics of CSF and frontal cortex grey and white matter in control, mild cognitive impairment, and Alzheimer's disease subjects

Novel antigenic determinant expressed in neurons of the dorsolateral hypothalamus in rat and human