List of works - Ennio Prosperi

2-Methoxyestradiol: new perspectives in colon carcinoma treatment

scientific article published on 15 September 2010

A functional in vitro cell-free system for studying DNA repair in isolated nuclei

scientific article published on 06 May 2020

An active mechanism flanks and modulates the export of the small ribosomal subunits.

scientific article published on 18 March 2009

Analysis of p21CDKN1A recruitment to DNA excision repair foci in the UV-induced DNA damage response

scientific article published in January 2004

Analysis of proliferating cell nuclear antigen (PCNA) associated with DNA.

scientific article

Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure-activity relationships and molecular modeling studies.

scientific article published on 12 May 2007

Arylthioindoles: Promising compounds against cancer cell proliferation

scientific article published on January 2010

CREBBP and p300 lysine acetyl transferases in the DNA damage response

scientific article published on 23 November 2017

DDB2 association with PCNA is required for its degradation after UV-induced DNA damage

scientific article published on 4 November 2013

Degradation of p21CDKN1A after DNA damage is independent of type of lesion, and is not required for DNA repair.

scientific article published on 24 March 2009

Distinct pools of proliferating cell nuclear antigen associated to DNA replication sites interact with the p125 subunit of DNA polymerase delta or DNA ligase I.

scientific article published on February 2004

Generation of the Rubinstein-Taybi syndrome type 2 patient-derived induced pluripotent stem cell line (IAIi001-A) carrying the EP300 exon 23 stop mutation c.3829A > T, p.(Lys1277*)

scientific article published on 18 June 2018

Helicobacter pylori releases a factor(s) inhibiting cell cycle progression of human gastric cell lines by affecting cyclin E/cdk2 kinase activity and Rb protein phosphorylation through enhanced p27(KIP1) protein expression

scientific article published on November 2002

Human proliferating cell nuclear antigen, poly(ADP-ribose) polymerase-1, and p21waf1/cip1. A dynamic exchange of partners

scientific article (publication date: 10 October 2003)

In Situ Analysis of DNA-Protein Complex Formation upon Radiation-Induced DNA Damage

scientific article published on 15 November 2019

Interaction of p21(CDKN1A) with PCNA regulates the histone acetyltransferase activity of p300 in nucleotide excision repair

scientific article published on 7 February 2008

Intracellular localization of the cyclin-dependent kinase inhibitor p21CDKN1A-GFP fusion protein during cell cycle arrest

scientific article

Killing of tumor cells: a drama in two acts

scientific article published on 27 May 2011

Loss of histone H2AX increases sensitivity of immortalized mouse fibroblasts to the topoisomerase II inhibitor etoposide.

scientific article published in September 2008

Loss of p21 CDKN1A impairs entry to quiescence and activates a DNA damage response in normal fibroblasts induced to quiescence

scientific article published on 01 January 2009

Multiple effects of berberine derivatives on colon cancer cells.

scientific article published on 18 June 2014

Multiple roles of the cell cycle inhibitor p21(CDKN1A) in the DNA damage response.

scientific article published on 22 January 2010

Replication fork stalling in WRN-deficient cells is overcome by prompt activation of a MUS81-dependent pathway

scientific article published on 13 October 2008

Replication-dependent DNA damage response triggered by roscovitine induces an uncoupling of DNA replication proteins.

scientific article

Small ribosomal subunits associate with nuclear myosin and actin in transit to the nuclear pores.

scientific article

Spatiotemporal dynamics of p21CDKN1A protein recruitment to DNA-damage sites and interaction with proliferating cell nuclear antigen

scientific article published on 21 March 2006

Study of the effects of a new pyrazolecarboxamide: changes in mitochondria and induction of apoptosis

scientific article published on 18 April 2009

Targeting Proliferating Cell Nuclear Antigen (PCNA) as an Effective Strategy to Inhibit Tumor Cell Proliferation

scientific article published on 15 January 2020

The fellowship of the rings: distinct pools of proliferating cell nuclear antigen trimer at work.

scientific article

p21CDKN1A does not interfere with loading of PCNA at DNA replication sites, but inhibits subsequent binding of DNA polymerase delta at the G1/S phase transition

scientific article published on 01 November 2003

p21CDKN1A participates in base excision repair by regulating the activity of poly(ADP-ribose) polymerase-1.

scientific article published on 19 March 2010

p300/CBP acetyl transferases interact with and acetylate the nucleotide excision repair factor XPG.

scientific article published on 3 September 2012

List of works by Ennio Prosperi

2-Methoxyestradiol: new perspectives in colon carcinoma treatment

A functional in vitro cell-free system for studying DNA repair in isolated nuclei

An active mechanism flanks and modulates the export of the small ribosomal subunits.

Analysis of p21CDKN1A recruitment to DNA excision repair foci in the UV-induced DNA damage response

Analysis of proliferating cell nuclear antigen (PCNA) associated with DNA.

Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure-activity relationships and molecular modeling studies.

Arylthioindoles: Promising compounds against cancer cell proliferation

CREBBP and p300 lysine acetyl transferases in the DNA damage response

DDB2 association with PCNA is required for its degradation after UV-induced DNA damage

Degradation of p21CDKN1A after DNA damage is independent of type of lesion, and is not required for DNA repair.

Distinct pools of proliferating cell nuclear antigen associated to DNA replication sites interact with the p125 subunit of DNA polymerase delta or DNA ligase I.

Generation of the Rubinstein-Taybi syndrome type 2 patient-derived induced pluripotent stem cell line (IAIi001-A) carrying the EP300 exon 23 stop mutation c.3829A > T, p.(Lys1277*)

Helicobacter pylori releases a factor(s) inhibiting cell cycle progression of human gastric cell lines by affecting cyclin E/cdk2 kinase activity and Rb protein phosphorylation through enhanced p27(KIP1) protein expression

Human proliferating cell nuclear antigen, poly(ADP-ribose) polymerase-1, and p21waf1/cip1. A dynamic exchange of partners

In Situ Analysis of DNA-Protein Complex Formation upon Radiation-Induced DNA Damage

Interaction of p21(CDKN1A) with PCNA regulates the histone acetyltransferase activity of p300 in nucleotide excision repair

Intracellular localization of the cyclin-dependent kinase inhibitor p21CDKN1A-GFP fusion protein during cell cycle arrest

Killing of tumor cells: a drama in two acts

Loss of histone H2AX increases sensitivity of immortalized mouse fibroblasts to the topoisomerase II inhibitor etoposide.

Loss of p21 CDKN1A impairs entry to quiescence and activates a DNA damage response in normal fibroblasts induced to quiescence

Multiple effects of berberine derivatives on colon cancer cells.

Multiple roles of the cell cycle inhibitor p21(CDKN1A) in the DNA damage response.

Replication fork stalling in WRN-deficient cells is overcome by prompt activation of a MUS81-dependent pathway

Replication-dependent DNA damage response triggered by roscovitine induces an uncoupling of DNA replication proteins.

Small ribosomal subunits associate with nuclear myosin and actin in transit to the nuclear pores.

Spatiotemporal dynamics of p21CDKN1A protein recruitment to DNA-damage sites and interaction with proliferating cell nuclear antigen

Study of the effects of a new pyrazolecarboxamide: changes in mitochondria and induction of apoptosis

Targeting Proliferating Cell Nuclear Antigen (PCNA) as an Effective Strategy to Inhibit Tumor Cell Proliferation

The fellowship of the rings: distinct pools of proliferating cell nuclear antigen trimer at work.

p21CDKN1A does not interfere with loading of PCNA at DNA replication sites, but inhibits subsequent binding of DNA polymerase delta at the G1/S phase transition

p21CDKN1A participates in base excision repair by regulating the activity of poly(ADP-ribose) polymerase-1.

p300/CBP acetyl transferases interact with and acetylate the nucleotide excision repair factor XPG.

Generation of the Rubinstein-Taybi syndrome type 2 patient-derived induced pluripotent stem cell line (IAIi001-A) carrying the EP300 exon 23 stop mutation c.3829A > T, p.(Lys1277*)