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List of works by Dwight A. Towler

"Osteotropic" Wnt/LRP Signals: High-Wire Artists in a Balancing Act Regulating Aortic Structure and Function

scientific article published in March 2017

1,25-Dihydroxyvitamin D3 but not cinacalcet HCl (Sensipar/Mimpara) treatment mediates aortic calcification in a rat model of secondary hyperparathyroidism

scientific article published on 26 April 2005

A GTPase-activating protein binding protein (G3BP1) / antiviral protein relay conveys arteriosclerotic Wnt signals in aortic smooth muscle cells.

scientific article published on 6 April 2018

A dominant negative cadherin inhibits osteoblast differentiation

scientific article

AMPKα1: SUMO Wrestling Runx2 as a Strategy to Inhibit Arteriosclerotic Calcification

scientific article published on July 2016

Activation of vascular smooth muscle parathyroid hormone receptor inhibits Wnt/beta-catenin signaling and aortic fibrosis in diabetic arteriosclerosis

scientific article published on 20 May 2010

Acylation of cellular proteins with endogenously synthesized fatty acids

scientific article published in February 1986

Agonist-like SERM effects on ERalpha-mediated repression of MMP1 promoter activity predict in vivo effects on bone and uterus

scientific article published on 20 April 2008

An osteopontin-NADPH oxidase signaling cascade promotes pro-matrix metalloproteinase 9 activation in aortic mesenchymal cells

scientific article published on 18 May 2006

Androgenic induction of growth and differentiation in the rodent uterus involves the modulation of estrogen-regulated genetic pathways.

scientific article published on 21 October 2004

Aortic Msx2-Wnt calcification cascade is regulated by TNF-alpha-dependent signals in diabetic Ldlr-/- mice

scientific article published on 11 October 2007

Arterial Calcification in Diabetes Mellitus: Preclinical Models and Translational Implications.

scientific article published on 22 December 2016

Arterial calcification and bone physiology: role of the bone–vascular axis ⬇️

scientific article published on April 3, 2012

Arteriosclerosis, bone biology, and calciotropic hormone signaling: learning the ABCs of disease in the bone-vascular axis

scientific article published on 17 September 2014

Arteriosclerotic Calcification: A Serpi(n)ginous Path to Cardiovascular Health?

scientific article

Author Correction: Skeletal and extraskeletal disorders of biomineralization

correction of a scholarly article

Bone morphogenetic proteins

scientific article published on September 2009

Calcific aortic valve disease: a consensus summary from the Alliance of Investigators on Calcific Aortic Valve Disease.

scientific article

Calcific aortic valve disease: not simply a degenerative process: A review and agenda for research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group. Executive summary: Calcific aortic valve disease-2011 update.

scientific article published in October 2011

Calciotropic hormones and arterial physiology: "D"-lightful insights

scientific article published on 01 February 2007

Cancer interaction with the bone microenvironment: a workshop of the National Institutes of Health Tumor Microenvironment Study Section

scientific article published in May 2006

Characterization of retinoic acid- and cell-dependent sequences which regulate zif268 gene expression in osteoblastic cells

scientific article published on November 1994

Chronic kidney disease: the "perfect storm" of cardiometabolic risk illuminates genetic diathesis in cardiovascular disease

scientific article published on 29 May 2013

Commonalities Between Vasculature and Bone: An Osseocentric View of Arteriosclerosis

scientific article published in January 2017

Control of rat tail skin temperature regulation by estrogen receptor-beta selective ligand

scientific article published on 12 August 2009

De novo lipogenesis maintains vascular homeostasis through endothelial nitric-oxide synthase (eNOS) palmitoylation.

scientific article

Diabetic foot osteomyelitis: bone markers and treatment outcomes.

scientific article published on 27 April 2012

Diet-induced diabetes activates an osteogenic gene regulatory program in the aortas of low density lipoprotein receptor-deficient mice

scientific article published on 01 November 1998

Dkk1 and MSX2-Wnt7b signaling reciprocally regulate the endothelial-mesenchymal transition in aortic endothelial cells

scientific article published on 16 May 2013

Ets domain transcription factor PE1 suppresses human interstitial collagenase promoter activity by antagonizing protein-DNA interactions at a critical AP1 element

scientific article

Fibroblast growth factor receptor signaling activates the human interstitial collagenase promoter via the bipartite Ets-AP1 element

scientific article published on July 1997

Gap junctional communication modulates gene transcription by altering the recruitment of Sp1 and Sp3 to connexin-response elements in osteoblast promoters.

scientific article published on 16 April 2003

Gestational exposure to ethanol suppresses msx2 expression in developing mouse embryos.

scientific article published on July 1997

Identification of a rat osteocalcin promoter 3',5'-cyclic adenosine monophosphate response region containing two PuGGTCA steroid hormone receptor binding motifs

scientific article published on March 1995

Imaging aortic matrix metabolism: mirabile visu!

scientific article published on 01 January 2007

Improving mass measurement of coronary artery calcification using threshold correction and thin collimation in multi-detector row computed tomography: in vitro experiment

scientific article published in September 2003

In memorium: Gideon Rodan M.D., Ph.D.

scientific article published in April 2006

Inorganic pyrophosphate: a paracrine regulator of vascular calcification and smooth muscle phenotype

scientific article published on 01 April 2005

MINT, the Msx2 interacting nuclear matrix target, enhances Runx2-dependent activation of the osteocalcin fibroblast growth factor response element

scientific article published on 6 May 2004

MSX2 promotes osteogenesis and suppresses adipogenic differentiation of multipotent mesenchymal progenitors.

scientific article

Mitochondrial ROS deficiency and diabetic complications: AMP[K]-lifying the adaptation to hyperglycemia

scientific article published on 25 October 2013

Molecular and cellular aspects of calcific aortic valve disease

scientific article

Nutrition in Cardioskeletal Health.

scientific article published on 16 May 2016

Osteopontin promoter polymorphism is associated with increased carotid intima-media thickness

scientific article published on 11 April 2008

Osteopontin transcription in aortic vascular smooth muscle cells is controlled by glucose-regulated upstream stimulatory factor and activator protein-1 activities

scientific journal article

Oxidation, inflammation, and aortic valve calcification peroxide paves an osteogenic path

scientific article published in September 2008

Purification and characterization of yeast myristoyl CoA:protein N-myristoyltransferase.

scientific article

Reciprocal regulation of osteocalcin transcription by the homeodomain proteins Msx2 and Dlx5.

scientific article

Reciprocal temporospatial patterns of Msx2 and Osteocalcin gene expression during murine odontogenesis

scientific article published in April 1998

Regulation of osteocalcin gene expression by a novel Ku antigen transcription factor complex

scientific article

Runx2 trans-activation mediated by the MSX2-interacting nuclear target requires homeodomain interacting protein kinase-3.

scientific article

Skeletal anabolism, PTH, and the bone-vascular axis.

scientific article

Skeletal and extraskeletal disorders of biomineralization

scientific article published in 2022

Smooth muscle cell plasticity: fact or fiction?

scientific article

Stage-specific expression of Dlx-5 during osteoblast differentiation: involvement in regulation of osteocalcin gene expression.

scientific article

Stimulus-selective inhibition of rat osteocalcin promoter induction and protein-DNA interactions by the homeodomain repressor Msx2.

scientific article published on November 1997

Stress fracture healing: fatigue loading of the rat ulna induces upregulation in expression of osteogenic and angiogenic genes that mimic the intramembranous portion of fracture repair

scientific article published on 7 October 2008

Structure−Function Analysis of Msx2-Mediated Transcriptional Suppression ⬇️

scientific article (publication date: 26 August 1997)

TNFR1-activated reactive oxidative species signals up-regulate osteogenic Msx2 programs in aortic myofibroblasts.

scientific article

Targeted reduction of vascular Msx1 and Msx2 mitigates arteriosclerotic calcification and aortic stiffness in LDLR-deficient mice fed diabetogenic diets

scientific article

Teriparatide (human parathyroid hormone (1-34)) inhibits osteogenic vascular calcification in diabetic low density lipoprotein receptor-deficient mice

scientific article published on 22 September 2003

The Long Noncoding RNA SPRIGHTLY Regulates Cell Proliferation in Primary Human Melanocytes

scientific article published on 29 January 2016

The alchemy of tendon repair: a primer for the (S)mad scientist

scientific article published on April 2006

The platelet: sensing shear and the endocrine regulation of cardiovascular sclerosis.

scientific article

The rat osteocalcin fibroblast growth factor (FGF)-responsive element: an okadaic acid-sensitive, FGF-selective transcriptional response motif

scientific article published on August 1996

Thematic series on the pathobiology of vascular calcification: an introduction.

scientific article published on May 2011

Transcriptional regulation of SM22alpha by Wnt3a: convergence with TGFbeta(1)/Smad signaling at a novel regulatory element.

scientific article published on 21 January 2009

Vascular Bmp Msx2 Wnt signaling and oxidative stress in arterial calcification

scientific article

Vascular calcification and aortic fibrosis: a bifunctional role for osteopontin in diabetic arteriosclerosis

scientific article

Vascular calcification: it's all the RAGE!

scientific article published on February 2011

Vascular calcification: the killer of patients with chronic kidney disease

scientific article published on 28 May 2009

Vascular smooth muscle LRP6 limits arteriosclerotic calcification in diabetic LDLR-/- mice by restraining noncanonical Wnt signals

scientific article published in June 2015

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