Search filters

List of works by Alastair J. Barr

Agonist-independent activation of Gz by the 5-hydroxytryptamine1A receptor co-expressed in Spodoptera frugiperda cells. Distinguishing inverse agonists from neutral antagonists

scientific article published on December 1997

Analysis of Receptor-Type Protein Tyrosine Phosphatase Extracellular Regions with Insights from AlphaFold

scientific article published in 2024

CD148 enhances platelet responsiveness to collagen by maintaining a pool of active Src family kinases.

scientific article published on 23 March 2010

Congenital macrothrombocytopenia with focal myelofibrosis due to mutations in human G6b-B is rescued in humanized mice

scientific article published on 13 June 2018

Crystal Structures of ABL-Related Gene (ABL2) in Complex with Imatinib, Tozasertib (VX-680), and a Type I Inhibitor of the Triazole Carbothioamide Class

scientific article

Crystal structure of human protein tyrosine phosphatase 14 (PTPN14) at 1.65-A resolution

scientific article

Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases

scientific article

Defining the molecular basis of interaction between R3 receptor-type protein tyrosine phosphatases and VE-cadherin

scientific article published on 19 September 2017

Differential regulation of formyl peptide and platelet-activating factor receptors. Role of phospholipase Cbeta3 phosphorylation by protein kinase A.

scientific article published on May 1998

HD-PTP is a catalytically inactive tyrosine phosphatase due to a conserved divergence in its phosphatase domain

scientific article

Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B

scientific article published on 22 August 2019

Identification of a region at the N-terminus of phospholipase C-beta 3 that interacts with G protein beta gamma subunits

scientific article published on 01 February 2000

Large-scale structural analysis of the classical human protein tyrosine phosphatome

scientific article

MAPK-specific tyrosine phosphatases: new targets for drug discovery?

scientific article published on 21 August 2006

Non-peptide antagonists, CP-96,345 and RP 67580, distinguish species variants in tachykinin NK1 receptors.

scientific article published in January 1993

Phospholipase C-beta 2 interacts with mitogen-activated protein kinase kinase 3

scientific article (publication date: 26 April 2002)

Protein Tyrosine Phosphatases as Drug Targets: Strategies and Challenges of Inhibitor Development ⬇️

scientific article published on October 1, 2010

RGS4 inhibits platelet-activating factor receptor phosphorylation and cellular responses

scientific article (publication date: 27 March 2001)

Reconstitution of receptors and GTP-binding regulatory proteins (G proteins) in Sf9 cells. A direct evaluation of selectivity in receptor.G protein coupling

scientific article published on January 1997

Sequence-specific 1H, 13C and 15N backbone resonance assignments of the 34 kDa catalytic domain of human PTPN7.

scientific article published on 30 May 2008

Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states

scientific article

Targeting Receptor-Type Protein Tyrosine Phosphatases with Biotherapeutics: Is Outside-in Better than Inside-Out?

scientific article published on 02 March 2018

Targeting protein tyrosine phosphatase SHP2 for therapeutic intervention

scientific article

The biochemical basis of disease

scholarly article by Alastair J. Barr published in December 2018

The crystal structure of human receptor protein tyrosine phosphatase kappa phosphatase domain 1

scientific article

The presence of NK3 tachykinin receptors on rat uterus

scientific article published on 01 October 1991

Paulina is supported by:

About Paulina

Help