List of works - Thierry Soldati

A brief historical and evolutionary perspective on the origin of cellular microbiology research

scientific article published on 19 July 2019

A dibasic motif in the tail of a class XIV apicomplexan myosin is an essential determinant of plasma membrane localization

scientific article

A microfluidic cell-trapping device for single-cell tracking of host-microbe interactions

scientific article published on 18 July 2016

A myosin I is involved in membrane recycling from early endosomes

scientific article published on September 2000

A myosin IK-Abp1-PakB circuit acts as a switch to regulate phagocytosis efficiency

scientific article

A potentially exhaustive screening strategy reveals two novel divergent myosins in Dictyostelium.

scientific article

Actin polymerization driven by WASH causes V-ATPase retrieval and vesicle neutralization before exocytosis ⬇️

scientific article

Adrenergic antagonists restrict replication of Legionella

scientific article

Alternative ribosomal initiation gives rise to chicken brain-type creatine kinase isoproteins with heterogeneous amino termini.

scientific article published in March 1990

Amoebae-Based Screening Reveals a Novel Family of Compounds Restricting Intracellular Legionella pneumophila

scientific article

Antimycobacterial activity in a single-cell infection assay of ellagitannins from Combretum aculeatum and their bioavailable metabolites

scientific article published on 23 March 2019

Antimycobacterial drug discovery using Mycobacteria-infected amoebae identifies anti-infectives and new molecular targets.

scientific article published on 2 March 2018

Autophagy in Dictyostelium: Mechanisms, regulation and disease in a simple biomedical model.

scientific article published on 7 October 2016

Autophagy in Dictyostelium: genes and pathways, cell death and infection

scientific article published on 28 August 2010

Autophagy researchers

Breaking fat! How mycobacteria and other intracellular pathogens manipulate host lipid droplets

scientific article published on 3 June 2017

Ca2+-Triggered Peptide Secretion in Single Cells Imaged with Green Fluorescent Protein and Evanescent-Wave Microscopy

scientific article published on 01 June 1997

Cellular Microbiology 1999-2019

scientific article published on 02 September 2019

Charged solvatochromic dyes as signal transducers in pH independent fluorescent and colorimetric ion selective nanosensors.

scientific article published on 9 September 2015

Conidial Melanin of the Human-Pathogenic Fungus Aspergillus fumigatus Disrupts Cell Autonomous Defenses in Amoebae

scientific article published on 26 May 2020

Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162].

scientific article published on 26 October 2017

Detecting, visualizing and quantitating the generation of reactive oxygen species in an amoeba model system

scientific article

Dictyostelium EHD associates with Dynamin and participates in phagosome maturation.

scientific article published on 11 May 2016

Dictyostelium discoideum flotillin homologues are essential for phagocytosis and participate in plasma membrane recycling and lysosome biogenesis

Dictyostelium discoideumprotein disulfide isomerase, an endoplasmic reticulum resident enzyme lacking a KDEL-type retrieval signal

article

Dictyostelium myosin IK is involved in the maintenance of cortical tension and affects motility and phagocytosis

scientific article published on February 2000

Dissection of amoeboid movement into two mechanically distinct modes.

scientific article

Distinct Mycobacterium marinum phosphatases determine pathogen vacuole phosphoinositide pattern, phagosome maturation, and escape to the cytosol

scientific article published on 07 February 2019

Do Class I Myosins Exert Their Functions through Regulation of Actin Dynamics?

article

Dual targeting of antioxidant and metabolic enzymes to the mitochondrion and the apicoplast of Toxoplasma gondii

scientific article (publication date: 31 August 2007)

Dynamin A, Myosin IB and Abp1 Couple Phagosome Maturation to F-Actin Binding

scientific article published on 26 October 2011

ESCRT and autophagy cooperate to repair ESX-1-dependent damage to the Mycobacterium-containing vacuole

Eat Prey, Live: Dictyostelium discoideum As a Model for Cell-Autonomous Defenses.

scientific article published in January 2017

Eat, kill or die: when amoeba meets bacteria

scientific article

Editorial: Amoebae as Host Models to Study the Interaction With Pathogens

scientific article published on 19 March 2019

Establishment and validation of whole-cell based fluorescence assays to identify anti-mycobacterial compounds using the Acanthamoeba castellanii-Mycobacterium marinum host-pathogen system

scientific article (publication date: 2014)

Ethane-freezing/methanol-fixation of cell monolayers: a procedure for improved preservation of structure and antigenicity for light and electron microscopies.

scientific article published on January 1998

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).

scientific article published on 18 May 2017

Evolution of the ferric reductase domain (FRD) superfamily: modularity, functional diversification, and signature motifs

scientific article

Exploring anti-bacterial compounds against intracellular Legionella

scientific article

Expression of Rab9 protein in Escherichia coli: purification and isoprenylation in vitro

scientific article

Flotillin and RacH modulate the intracellular immunity of Dictyostelium to Mycobacterium marinum infection

scientific article published on 24 June 2007

Flotillin and RacH modulate the intracellular immunity of Dictyostelium to Mycobacterium marinum infection

Functions of theDictyosteliumLIMP-2 and CD36 homologues in bacteria uptake, phagolysosome biogenesis and host cell defence

scientific article published on 03 September 2018

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

High-resolution dissection of phagosome maturation reveals distinct membrane trafficking phases

scientific article

In Silico Driven Design and Synthesis of Rhodanine Derivatives as Novel Antibacterials Targeting the Enoyl Reductase InhA.

scientific article published on 5 January 2016

Infection by tubercular mycobacteria is spread by nonlytic ejection from their amoeba hosts

scientific article

Inhibitors of Mycobacterium marinum virulence identified in a Dictyostelium discoideum host model

scientific article published on 20 July 2017

Intracompartmental sorting of essential myosin light chains: molecular dissection and in vivo monitoring by epitope tagging.

scientific article

Involvement of the AP-1 adaptor complex in early steps of phagocytosis and macropinocytosis

scientific article published on 14 November 2003

Lipid droplet dynamics at early stages of Mycobacterium marinum infection in Dictyostelium

scientific article

Live imaging of Mycobacterium marinum infection in Dictyostelium discoideum

scientific article published on January 2015

Localization of all four ZnT zinc transporters in Dictyostelium and impact of ZntA and ZntB knockout on bacteria killing

scientific article published in 2018

Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network

scientific journal article

Maturation Changes in Purified Phagosomes

scientific article published on 01 January 2008

Membrane targeting of the small GTPase Rab9 is accompanied by nucleotide exchange

scientific article published in May 1994

Methods to Monitor and Quantify Autophagy in the Social Amoeba Dictyostelium discoideum

scientific article published on 3 July 2017

Mitochondrial translation in absence of local tRNA aminoacylation and methionyl tRNA Met formylation in Apicomplexa

scientific article published on 8 April 2010

Molecular characterization of the evolution of phagosomes

scientific article

Molecular mechanisms of membrane trafficking. What do we learn from Dictyostelium discoideum?

scientific article published in October 1999

Morphology and dynamics of the endocytic pathway in Dictyostelium discoideum

scientific article

Mucolipin controls lysosome exocytosis in Dictyostelium

scientific article published on 22 February 2012

Mycobacteria and the Intraphagosomal Environment: Take It With a Pinch of Salt(s)!

Mycobacteria and the intraphagosomal environment: take it with a pinch of salt(s)!

scientific article published on 17 April 2012

Mycobacterium Marinum

Mycobacterium bovis uses the ESX-1 Type VII secretion system to escape predation by the soil-dwelling amoeba Dictyostelium discoideum

scientific article published on 02 January 2020

Mycobacterium marinum Degrades Both Triacylglycerols and Phospholipids from Its Dictyostelium Host to Synthesise Its Own Triacylglycerols and Generate Lipid Inclusions

scientific article

Mycobacterium marinum antagonistically induces an autophagic response while repressing the autophagic flux in a TORC1- and ESX-1-dependent manner

scientific article

Mycobacterium marinum produces distinct mycobactin and carboxymycobactin siderophores to promote growth in broth and phagocytes

scientific article published on 11 February 2020

Myosin-I nomenclature.

scientific article

Of Amoebae and Men: Extracellular DNA Traps as an Ancient Cell-Intrinsic Defense Mechanism

scientific article published on 08 July 2016

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

scientific article (publication date: July 2016)

Optimized Fixation and Immunofluorescence Staining Methods for Dictyostelium Cells

scientific article published on 01 January 2006

PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection

article

Phagosome Proteomes Unite! A Virtual Model of Maturation as a Tool to Study Pathogen-Induced Changes

Phosphorylation of chicken brain-type creatine kinase affects a physiologically important kinetic parameter and gives rise to protein microheterogeneity in vivo

scientific article published in September 1990

Potassium Sensitive Optical Nanosensors Containing Voltage Sensitive Dyes.

scientific article published in January 2015

Powering membrane traffic in endocytosis and recycling

scientific article published on 8 November 2006

Preparation of intact, highly purified phagosomes from Dictyostelium

scientific article published in January 2006

Prison break: pathogens' strategies to egress from host cells

scientific article

Production of Reagents and Optimization of Methods for Studying Calmodulin-Binding Proteins

article

Proteomic characterization of the Mycobacterium marinum-containing vacuole in Dictyostelium discoideum

Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake

scientific article published on 22 August 2006

Quantitative analysis of phagocytosis and phagosome maturation

scientific article published in January 2013

Rab GDI: a solubilizing and recycling factor for rab9 protein

scientific article

Rab GDP dissociation inhibitor: putting rab GTPases in the right place.

scientific article

Rab-GDI presents functional Rab9 to the intracellular transport machinery and contributes selectivity to Rab9 membrane recruitment.

scientific article published in June 1994

Rab7 and Rab9 are recruited onto late endosomes by biochemically distinguishable processes

scientific article

Rab8a regulates the exocyst-mediated kiss-and-run discharge of the Dictyostelium contractile vacuole

scientific article published on 9 February 2012

Rab9 functions in transport between late endosomes and the trans Golgi network

scientific journal article

Reactive oxygen species and mitochondria: A nexus of cellular homeostasis

scientific article

Reconstitution of Rab9 endosomal targeting and nucleotide exchange using purified Rab9-GDP dissociation inhibitor complexes and endosome-enriched membranes

scientific article published on January 1995

Regulation of aggregate size and pattern by adenosine and caffeine in cellular slime molds

scientific article

Role of actin cortex in the subplasmalemmal transport of secretory granules in PC-12 cells.

scientific article published on June 2000

Role of magnesium and a phagosomal P-type ATPase in intracellular bacterial killing

scientific article

Secreted heme peroxidase from Dictyostelium discoideum: Insights into catalysis, structure, and biological role.

scientific article published on 14 December 2017

Selective membrane recruitment of Rab GTPases

scientific article published on January 1995

Setting up and monitoring an infection of Dictyostelium discoideum with mycobacteria

scientific article

Social amoebae trap and kill bacteria by casting DNA nets

scientific article

Survey on medicinal plants traditionally used in Senegal for the treatment of tuberculosis (TB) and assessment of their antimycobacterial activity

scientific article published on 28 December 2017

The Biochemistry Department of the University of Geneva: Understanding the Molecular Basis and Function of Intracellular Organization

scientific article published in December 2009

The ESCRT and autophagy machineries cooperate to repair ESX-1-dependent damage at the Mycobacterium-containing vacuole but have opposite impact on containing the infection

scientific article published on 31 December 2018

The Saposin-Like Protein AplD Displays Pore-Forming Activity and Participates in Defense Against Bacterial Infection During a Multicellular Stage of Dictyostelium discoideum

scientific article

The autophagic machinery ensures nonlytic transmission of mycobacteria

scientific article

The balance in the delivery of ER components and the vacuolar proton pump to the phagosome depends on myosin IK in Dictyostelium

scientific article

The developmental cycle of Dictyostelium discoideum ensures curing of a mycobacterial infection at both cell-autonomous level and by collaborative exclusion

Think zinc: Role of zinc poisoning in the intraphagosomal killing of bacteria by the amoeba Dictyostelium

Time-resolved RNA-seq profiling of the infection of Dictyostelium discoideum by Mycobacterium marinum reveals an integrated host response to damage and stress

scholarly article published 27 March 2019

Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plus-end-directed motor

scientific article

Toxoplasma gondii myosins B/C: one gene, two tails, two localizations, and a role in parasite division

scientific article

Transport from late endosomes to trans-Golgi network in semiintact cell extracts

scientific article

Unconventional Myosins, Actin Dynamics and Endocytosis: A Ménage à Trois? ⬇️

scientific article published on June 1, 2003

Unconventional myosins at the crossroad of signal transduction and cytoskeleton remodeling

scientific article published in January 1999

Vacuolins and myosin VII are required for phagocytic uptake and phagosomal membrane recycling in Dictyostelium discoideum

scientific article published on 01 June 2020

Vps13F links bacterial recognition and intracellular killing in Dictyostelium

scientific article

WASH drives early recycling from macropinosomes and phagosomes to maintain surface phagocytic receptors

scientific article published on 19 September 2016

WASH is required for lysosomal recycling and efficient autophagic and phagocytic digestion

scientific article published on 24 July 2013

When Dicty Met Myco, a (Not So) Romantic Story about One Amoeba and Its Intracellular Pathogen

scientific article published in January 2017

List of works by Thierry Soldati

A brief historical and evolutionary perspective on the origin of cellular microbiology research

A dibasic motif in the tail of a class XIV apicomplexan myosin is an essential determinant of plasma membrane localization

A microfluidic cell-trapping device for single-cell tracking of host-microbe interactions

A myosin I is involved in membrane recycling from early endosomes

A myosin IK-Abp1-PakB circuit acts as a switch to regulate phagocytosis efficiency

A potentially exhaustive screening strategy reveals two novel divergent myosins in Dictyostelium.

Actin polymerization driven by WASH causes V-ATPase retrieval and vesicle neutralization before exocytosis ⬇️

Adrenergic antagonists restrict replication of Legionella

Alternative ribosomal initiation gives rise to chicken brain-type creatine kinase isoproteins with heterogeneous amino termini.

Amoebae-Based Screening Reveals a Novel Family of Compounds Restricting Intracellular Legionella pneumophila

Antimycobacterial activity in a single-cell infection assay of ellagitannins from Combretum aculeatum and their bioavailable metabolites

Antimycobacterial drug discovery using Mycobacteria-infected amoebae identifies anti-infectives and new molecular targets.

Autophagy in Dictyostelium: Mechanisms, regulation and disease in a simple biomedical model.

Autophagy in Dictyostelium: genes and pathways, cell death and infection

Autophagy researchers

Breaking fat! How mycobacteria and other intracellular pathogens manipulate host lipid droplets

Ca2+-Triggered Peptide Secretion in Single Cells Imaged with Green Fluorescent Protein and Evanescent-Wave Microscopy

Cellular Microbiology 1999-2019

Charged solvatochromic dyes as signal transducers in pH independent fluorescent and colorimetric ion selective nanosensors.

Conidial Melanin of the Human-Pathogenic Fungus Aspergillus fumigatus Disrupts Cell Autonomous Defenses in Amoebae

Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162].

Detecting, visualizing and quantitating the generation of reactive oxygen species in an amoeba model system

Dictyostelium EHD associates with Dynamin and participates in phagosome maturation.

Dictyostelium discoideum flotillin homologues are essential for phagocytosis and participate in plasma membrane recycling and lysosome biogenesis

Dictyostelium discoideumprotein disulfide isomerase, an endoplasmic reticulum resident enzyme lacking a KDEL-type retrieval signal

Dictyostelium myosin IK is involved in the maintenance of cortical tension and affects motility and phagocytosis

Dissection of amoeboid movement into two mechanically distinct modes.

Distinct Mycobacterium marinum phosphatases determine pathogen vacuole phosphoinositide pattern, phagosome maturation, and escape to the cytosol

Do Class I Myosins Exert Their Functions through Regulation of Actin Dynamics?

Dual targeting of antioxidant and metabolic enzymes to the mitochondrion and the apicoplast of Toxoplasma gondii

Dynamin A, Myosin IB and Abp1 Couple Phagosome Maturation to F-Actin Binding

ESCRT and autophagy cooperate to repair ESX-1-dependent damage to the Mycobacterium-containing vacuole

Eat Prey, Live: Dictyostelium discoideum As a Model for Cell-Autonomous Defenses.

Eat, kill or die: when amoeba meets bacteria

Editorial: Amoebae as Host Models to Study the Interaction With Pathogens

Establishment and validation of whole-cell based fluorescence assays to identify anti-mycobacterial compounds using the Acanthamoeba castellanii-Mycobacterium marinum host-pathogen system

Ethane-freezing/methanol-fixation of cell monolayers: a procedure for improved preservation of structure and antigenicity for light and electron microscopies.

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).

Evolution of the ferric reductase domain (FRD) superfamily: modularity, functional diversification, and signature motifs

Exploring anti-bacterial compounds against intracellular Legionella

Expression of Rab9 protein in Escherichia coli: purification and isoprenylation in vitro

Flotillin and RacH modulate the intracellular immunity of Dictyostelium to Mycobacterium marinum infection

Flotillin and RacH modulate the intracellular immunity of Dictyostelium to Mycobacterium marinum infection

Functions of theDictyosteliumLIMP-2 and CD36 homologues in bacteria uptake, phagolysosome biogenesis and host cell defence

Guidelines for the use and interpretation of assays for monitoring autophagy

High-resolution dissection of phagosome maturation reveals distinct membrane trafficking phases

In Silico Driven Design and Synthesis of Rhodanine Derivatives as Novel Antibacterials Targeting the Enoyl Reductase InhA.

Infection by tubercular mycobacteria is spread by nonlytic ejection from their amoeba hosts

Inhibitors of Mycobacterium marinum virulence identified in a Dictyostelium discoideum host model

Intracompartmental sorting of essential myosin light chains: molecular dissection and in vivo monitoring by epitope tagging.

Involvement of the AP-1 adaptor complex in early steps of phagocytosis and macropinocytosis

Lipid droplet dynamics at early stages of Mycobacterium marinum infection in Dictyostelium

Live imaging of Mycobacterium marinum infection in Dictyostelium discoideum

Localization of all four ZnT zinc transporters in Dictyostelium and impact of ZntA and ZntB knockout on bacteria killing

Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network

Maturation Changes in Purified Phagosomes

Membrane targeting of the small GTPase Rab9 is accompanied by nucleotide exchange

Methods to Monitor and Quantify Autophagy in the Social Amoeba Dictyostelium discoideum

Mitochondrial translation in absence of local tRNA aminoacylation and methionyl tRNA Met formylation in Apicomplexa

Molecular characterization of the evolution of phagosomes

Molecular mechanisms of membrane trafficking. What do we learn from Dictyostelium discoideum?

Morphology and dynamics of the endocytic pathway in Dictyostelium discoideum

Mucolipin controls lysosome exocytosis in Dictyostelium

Mycobacteria and the Intraphagosomal Environment: Take It With a Pinch of Salt(s)!

Mycobacteria and the intraphagosomal environment: take it with a pinch of salt(s)!

Mycobacterium Marinum

Mycobacterium bovis uses the ESX-1 Type VII secretion system to escape predation by the soil-dwelling amoeba Dictyostelium discoideum

Mycobacterium marinum Degrades Both Triacylglycerols and Phospholipids from Its Dictyostelium Host to Synthesise Its Own Triacylglycerols and Generate Lipid Inclusions

Mycobacterium marinum antagonistically induces an autophagic response while repressing the autophagic flux in a TORC1- and ESX-1-dependent manner

Mycobacterium marinum produces distinct mycobactin and carboxymycobactin siderophores to promote growth in broth and phagocytes

Myosin-I nomenclature.

Of Amoebae and Men: Extracellular DNA Traps as an Ancient Cell-Intrinsic Defense Mechanism

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

Optimized Fixation and Immunofluorescence Staining Methods for Dictyostelium Cells

PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection

PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection

Phagosome Proteomes Unite! A Virtual Model of Maturation as a Tool to Study Pathogen-Induced Changes

Phosphorylation of chicken brain-type creatine kinase affects a physiologically important kinetic parameter and gives rise to protein microheterogeneity in vivo

Potassium Sensitive Optical Nanosensors Containing Voltage Sensitive Dyes.