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List of works by Isaac Almendros

A Novel Chip for Cyclic Stretch and Intermittent Hypoxia Cell Exposures Mimicking Obstructive Sleep Apnea

scientific article published on 29 July 2016

A prospective multicenter cohort study of cutaneous melanoma: clinical staging and potential associations with HIF-1α and VEGF expressions.

scientific article

Acetylsalicylic Acid Prevents Intermittent Hypoxia-Induced Vascular Remodeling in a Murine Model of Sleep Apnea.

scientific article published on 24 May 2018

Adipose tissue macrophage polarization by intermittent hypoxia in a mouse model of OSA: effect of tumor microenvironment

scientific article published on 14 March 2015

Ageing and chronic intermittent hypoxia mimicking sleep apnea do not modify local brain tissue stiffness in healthy mice

scientific article

Aging Reduces Intermittent Hypoxia-induced Lung Carcinoma Growth in a Mouse Model of Sleep Apnea

scientific article published on 01 November 2018

Altered CD8+ T-Cell Lymphocyte Function and TC1 Cell Stemness Contribute to Enhanced Malignant Tumor Properties in Murine Models of Sleep Apnea

scientific article

Alzheimer's Disease Mutant Mice Exhibit Reduced Brain Tissue Stiffness Compared to Wild-type Mice in both Normoxia and following Intermittent Hypoxia Mimicking Sleep Apnea

scientific article published on 19 January 2018

Aorta macrophage inflammatory and epigenetic changes in a murine model of obstructive sleep apnea: Potential role of CD36.

scientific article published on 27 February 2017

Aortic remodelling induced by obstructive apneas is normalized with mesenchymal stem cells infusion

scientific article published on 07 August 2019

Atrial fibrosis in a chronic murine model of obstructive sleep apnea: mechanisms and prevention by mesenchymal stem cells.

scientific article

Bioengineered Lungs: A Challenge and An Opportunity

scientific article published in November 2017

Biomarkers of carcinogenesis and tumour growth in patients with cutaneous melanoma and obstructive sleep apnoea.

scientific article published on 8 March 2018

Bioprintable Lung Extracellular Matrix Hydrogel Scaffolds for 3D Culture of Mesenchymal Stromal Cells

scientific article published in 2021

Brain tissue hypoxia and oxidative stress induced by obstructive apneas is different in young and aged rats.

scientific article published on July 2014

Cancer and Sleep Apnea: Cutaneous Melanoma as a Case Study

scientific article published on 01 December 2019

Changes in oxygen partial pressure of brain tissue in an animal model of obstructive apnea.

scientific article published on 15 January 2010

Chronic Sleep Disruption Alters Gut Microbiota, Induces Systemic and Adipose Tissue Inflammation and Insulin Resistance in Mice

scientific article published on 14 October 2016

Chronic intermittent hypoxia mimicking sleep apnoea increases spontaneous tumorigenesis in mice

scientific article

Circulating exosomes potentiate tumor malignant properties in a mouse model of chronic sleep fragmentation

scientific article published on 13 July 2016

Clinical physiology and sleep: highlights from the European Respiratory Society Congress 2018 presented by early career members

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Clinical physiology and sleep: insights from the European Respiratory Society Congress 2017.

scientific article published in November 2017

Differential effect of intermittent hypoxia and sleep fragmentation on PD-1/PD-L1 upregulation

scientific article published on 29 November 2019

Does obstructive sleep apnea confer risk to induce or enhance tumor malignancy?

scientific article published on 8 October 2015

ERS International Congress, Madrid, 2019: highlights from the Sleep and Clinical Physiology Assembly

scientific article published on 01 April 2020

Early Career Members at the ERS International Congress 2017: highlights from the Assemblies.

scientific article published in December 2017

Early Career Members at the ERS Lung Science Conference: cell-matrix interactions in lung disease and regeneration: Early career forum

scientific article published on 01 June 2018

Early Career Members at the Lung Science Conference and the Sleep and Breathing Conference 2019

scientific article published on 01 September 2019

Early and mid-term effects of obstructive apneas in myocardial injury and inflammation.

scientific article published on 26 October 2011

Early effects of continuous positive airway pressure in a rodent model of allergic rhinitis.

scientific article published on 5 November 2016

Early intermittent hypoxia induces proatherogenic changes in aortic wall macrophages in a murine model of obstructive sleep apnea

scientific article published in October 2014

Effect of resveratrol on visceral white adipose tissue inflammation and insulin sensitivity in a mouse model of sleep apnea

scientific article published on 9 October 2014

Effects of Sustained and Intermittent Hypoxia on Human Lung Cancer Cells

scientific article published on 01 October 2019

Effects of heated humidification on nasal inflammation in a CPAP rat model.

scientific article published on 9 March 2010

Exosomal Cargo Properties, Endothelial Function and Treatment of Obesity Hypoventilation Syndrome: A Proof of Concept Study

scientific article published on 15 May 2018

Exosomes and Metabolic Function in Mice Exposed to Alternating Dark-Light Cycles Mimicking Night Shift Work Schedules

scientific article

Fragmented sleep accelerates tumor growth and progression through recruitment of tumor-associated macrophages and TLR4 signaling

scientific article

Frequency and magnitude of intermittent hypoxia modulate endothelial wound healing in a cell culture model of sleep apnea

scientific article

Heterotypic paracrine signaling drives fibroblast senescence and tumor progression of large cell carcinoma of the lung

scientific article published on 30 June 2016

Highlights from the 2018 European Respiratory Society International Congress: sleep and clinical physiology

scientific article published on 08 July 2019

Hypoxia-induced PD-L1/PD-1 crosstalk impairs T-cell function in sleep apnoea.

scientific article

Increased upper airway collapsibility in a mouse model of Marfan syndrome.

scientific article published on 23 December 2014

Intermittent Hypoxia Is Associated With High Hypoxia Inducible Factor-1α but Not High Vascular Endothelial Growth Factor Cell Expression in Tumors of Cutaneous Melanoma Patients.

scientific article published on 26 April 2018

Intermittent Hypoxia Mimicking Sleep Apnea Increases Passive Stiffness of Myocardial Extracellular Matrix. A Multiscale Study

scientific article published on 15 August 2018

Intermittent Hypoxia Severity in Animal Models of Sleep Apnea

scientific article published on 06 November 2018

Intermittent Hypoxia-Induced Cardiovascular Remodeling Is Reversed by Normoxia in a Mouse Model of Sleep Apnea.

scientific article published on 13 January 2016

Intermittent hypoxia and cancer: Undesirable bed partners?

scientific article published on 14 August 2017

Intermittent hypoxia enhances cancer progression in a mouse model of sleep apnoea

scientific article published in January 2012

Intermittent hypoxia increases kidney tumor vascularization in a murine model of sleep apnea.

scientific article

Intermittent hypoxia increases melanoma metastasis to the lung in a mouse model of sleep apnea.

scientific article

Intermittent hypoxia-induced changes in tumor-associated macrophages and tumor malignancy in a mouse model of sleep apnea.

scientific article published on March 2014

Mesenchymal stem cells reduce inflammation in a rat model of obstructive sleep apnea.

scientific article published on 31 May 2010

Microarray-based analysis of plasma cirDNA epigenetic modification profiling in xenografted mice exposed to intermittent hypoxia

scientific article published on 13 May 2015

Normoxic Recovery Mimicking Treatment of Sleep Apnea Does Not Reverse Intermittent Hypoxia-Induced Bacterial Dysbiosis and Low-Grade Endotoxemia in Mice.

scientific article published on July 2016

Obesity and intermittent hypoxia increase tumor growth in a mouse model of sleep apnea

scientific article

Obesity, sleep apnea, and cancer

scientific article published on 18 February 2020

Obstructive Sleep Apnea and Atherosclerosis: Both the Gut Microbiome and Hypercapnia Matter.

scientific article

Obstructive sleep apnea and Fuhrman grade in patients with clear cell renal cell carcinoma treated surgically.

scientific article published on 23 April 2016

Obstructive sleep apnea intensifies stroke severity following middle cerebral artery occlusion

scientific article published on 29 January 2020

One-lung overventilation does not induce inflammation in the normally ventilated contralateral lung

scientific article published on 22 April 2008

Overnight Change in Urinary Prostacyclin and Thromboxane in Obstructive Sleep Apnea

scientific article published on 05 November 2018

Oxygen diffusion and consumption in extracellular matrix gels: implications for designing three-dimensional cultures.

scientific article published on 30 September 2013

Passive Stiffness of Left Ventricular Myocardial Tissue Is Reduced by Ovariectomy in a Post-menopause Mouse Model

scientific article published on 05 November 2018

Potential role of adult stem cells in obstructive sleep apnea

scientific article

Preview of Sleep and Breathing Conference 2019 and report on Early Career Member international collaboration

scientific article published on 01 March 2019

Prolonged Exposures to Intermittent Hypoxia Promote Visceral White Adipose Tissue Inflammation in a Murine Model of Severe Sleep Apnea: Effect of Normoxic Recovery

scientific article published on 22 December 2016

Relationship Between Sleep Apnea and Cancer.

scientific article published on 02 April 2015

Resveratrol attenuates intermittent hypoxia-induced macrophage migration to visceral white adipose tissue and insulin resistance in male mice

scientific article

Role of Cyclooxygenase-2 on Intermittent Hypoxia-Induced Lung Tumor Malignancy in a Mouse Model of Sleep Apnea.

scientific article published on 16 March 2017

Sex dimorphism in late gestational sleep fragmentation and metabolic dysfunction in offspring mice

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Sleep Apnea and Tumor Agressivity

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Sleep apnoea, insulin resistance and diabetes: the first step is in the fat.

scientific article published on 19 April 2017

Sleep-Disordered Breathing Is Independently Associated With Increased Aggressiveness of Cutaneous Melanoma: A Multicenter Observational Study in 443 Patients

scientific article published on 27 July 2018

Soluble PD-L1 is a potential biomarker of cutaneous melanoma aggressiveness and metastasis in obstructive sleep apnoea patients

scientific article published on 31 January 2019

Temporal trajectories of novel object recognition performance in mice exposed to intermittent hypoxia

scientific article published on 14 December 2017

The force loading rate drives cell mechanosensing through both reinforcement and cytoskeletal softening

scientific article published on 09 July 2021

Treatment with TUG891, a free fatty acid receptor 4 agonist, restores adipose tissue metabolic dysfunction following chronic sleep fragmentation in mice.

scientific article published on 16 March 2016

Tumor Cell Malignant Properties Are Enhanced by Circulating Exosomes in Sleep Apnea.

scientific article published on 25 August 2016

Understanding the Pathophysiological Mechanisms of Cardiometabolic Complications in Obstructive Sleep Apnoea - Towards Personalised Treatment Approaches

scientific article published on 07 April 2020

Upper airway collapse and reopening induce inflammation in a sleep apnoea model

scientific article published on 30 April 2008

Visceral White Adipose Tissue after Chronic Intermittent and Sustained Hypoxia in Mice.

scientific article

Why ERS Early Career Members should attend the International Congress 2019 in Madrid.

scientific article published in June 2019

Zooming in on the ERS fellowships and the International Congress.

scientific article