List of works - Takeo Nakanishi

A new orally active antitumor 1 R ,2 R -cyclohexanediamine-platinum(IV) complex: trans -( n -valerato)chloro(1 R ,2 R -cyclohexanediamine) (oxalato)platinum(IV)

scientific article published on 01 January 1999

A novel role for OATP2A1/SLCO2A1 in a murine model of colon cancer

scientific article published on 29 November 2017

A novel xenobiotic responsive element regulated by aryl hydrocarbon receptor is involved in the induction of BCRP/ABCG2 in LS174T cells.

scientific article

A role of prostaglandin transporter in regulating PGE₂ release from human bronchial epithelial BEAS-2B cells in response to LPS.

scientific article published on 29 April 2013

Accumulation of trans-1-amino-3-[(18)F]fluorocyclobutanecarboxylic acid in prostate cancer due to androgen-induced expression of amino acid transporters

scientific article

Active intestinal absorption of fluoroquinolone antibacterial agent ciprofloxacin by organic anion transporting polypeptide, Oatp1a5.

scientific article

An orally active antitumor cyclohexanediamine-Pt(IV) complex

scientific article published on 01 May 1996

Analysis of the Metabolic Pathway of Bosentan and of the Cytotoxicity of Bosentan Metabolites Based on a Quantitative Modeling of Metabolism and Transport in Sandwich-Cultured Human Hepatocytes.

scientific article published on 26 October 2015

Apple-derived Nanoparticles Modulate Expression of Organic-Anion-Transporting Polypeptide (OATP) 2B1 in Caco-2 Cells

scientific article published on 05 November 2018

Application of quantitative time-lapse imaging (QTLI) for evaluation of Mrp2-based drug-drug interaction induced by liver metabolites.

scientific article published on 2 July 2012

Association of miR-145 With Statin-Induced Skeletal Muscle Toxicity in Human Rhabdomyosarcoma RD Cells

scientific article published on 21 April 2017

Bcrp1 transcription in mouse testis is controlled by a promoter upstream of a novel first exon (E1U) regulated by steroidogenic factor-1

scientific article

Breast cancer resistance protein (BCRP/ABCG2): its role in multidrug resistance and regulation of its gene expression.

scientific article

Breast cancer resistance protein (BCRP/MXR/ABCG2) in acute myeloid leukemia: discordance between expression and function

scientific article published on July 2004

Breast cancer resistance protein (BCRP/MXR/ABCG2) in adult acute lymphoblastic leukaemia: frequent expression and possible correlation with shorter disease-free survival

scientific article

Cancer cell-targeted drug delivery utilizing oligopeptide transport activity

Cancer cell-targeted drug delivery utilizing oligopeptide transport activity.

scientific article published in October 2000

Cancer cells uptake porphyrinsviaheme carrier protein 1

Carnitine precursor γ-butyrobetaine is a novel substrate of the Na(+)- and Cl(-)-dependent GABA transporter Gat2.

scientific article published on 12 October 2011

Carrier-Mediated Prodrug Uptake to Improve the Oral Bioavailability of Polar Drugs: An Application to an Oseltamivir Analogue

scientific article (publication date: February 2016)

Characteristics of transcription-regulatory elements for gene expression from plasmid vectors in human trophoblast cell lines

scientific article published on 5 April 2006

Co-localization of microsomal prostaglandin E synthase-1 with cyclooxygenase-1 in layer II of murine placental syncytiotrophoblasts.

scientific article published on 6 April 2017

Comparison of transgene expression mediated by several Fiber-modified adenovirus vectors in trophoblast cells

scientific article published on 16 December 2004

Contribution of Equilibrative Nucleoside Transporters 1 and 2 to Gemcitabine Uptake in Pancreatic Cancer Cells.

scientific article published on 22 April 2018

Contribution of equilibrative nucleoside transporter(s) to intestinal basolateral and apical transports of anticancer trifluridine.

scientific article

Current Progress Toward a Better Understanding of Drug Disposition Within the Lungs: Summary Proceedings of the First Workshop on Drug Transporters in the Lungs.

scientific article published on 14 April 2017

Different Involvement of OAT in Renal Disposition of Oral Anticoagulants Rivaroxaban, Dabigatran, and Apixaban.

scientific article

Differential Effect of Grapefruit Juice on Intestinal Absorption of Statins Due to Inhibition of Organic Anion Transporting Polypeptide and/or P-glycoprotein

article

Direct evidence for peptide transporter (PepT1)-mediated uptake of a nonpeptide prodrug, valacyclovir

scientific article published in September 1998

Drug efflux by breast cancer resistance protein is a mechanism of resistance to the benzimidazole insulin-like growth factor receptor/insulin receptor inhibitor, BMS-536924

scientific article

Effect of back pressure on emulsification of lipid nanodispersions in a high-pressure homogenizer

scientific article published on 17 November 2011

Effect of tyrosine kinase inhibitors on renal handling of creatinine by MATE1.

scientific article published on 18 June 2018

Experimental Evidence for Resecretion of PGE2 across Rat Alveolar Epithelium by OATP2A1/SLCO2A1-Mediated Transcellular Transport

scientific article published on 12 November 2018

Functional Characterization of Apical Transporters Expressed in Rat Proximal Tubular Cells (PTCs) in Primary Culture

article

Functional characterization of human breast cancer resistance protein (BCRP, ABCG2) expressed in the oocytes of Xenopus laevis

scientific article

Functional cooperation of SMCTs and URAT1 for renal reabsorption transport of urate

scientific article published on 4 September 2012

Functional cooperation of URAT1 (SLC22A12) and URATv1 (SLC2A9) in renal reabsorption of urate

scientific article published on 4 January 2013

Functional cyclic AMP response element in the breast cancer resistance protein (BCRP/ABCG2) promoter modulates epidermal growth factor receptor pathway- or androgen withdrawal-mediated BCRP/ABCG2 transcription in human cancer cells.

scientific article

Functional pleiotropy of organic anion transporting polypeptide OATP2B1 due to multiple binding sites

scientific article published on 27 December 2011

Genetic polymorphisms of OATP transporters and their impact on intestinal absorption and hepatic disposition of drugs.

scientific article published on 20 December 2011

Hepatic uptake of gamma-butyrobetaine, a precursor of carnitine biosynthesis, in rats.

scientific article

How does whisky lower serum urate level?

scientific article published on 10 September 2013

Identification and characterization of the major alternative promoter regulating Bcrp1/Abcg2 expression in the mouse intestine

scientific article

Identification and functional characterization of uric acid transporter Urat1 (Slc22a12) in rats

scientific article published on 11 November 2010

Identification of MRP2 as a targetable factor limiting oxaliplatin accumulation and response in gastrointestinal cancer

scientific article published on 19 February 2019

Identification of the Uptake Transporter Responsible for Distribution of Acotiamide into Stomach Tissue

scientific article published on 10 March 2020

Immunolocalization and pharmacological relevance of oligopeptide transporter PepT1 in intestinal absorption of beta-lactam antibiotics

scientific article

Impact of FDA-Approved Drugs on the Prostaglandin Transporter OATP2A1/SLCO2A1.

scientific article

Impact of breast cancer resistance protein expression on the in vitro efficacy of anticancer drugs in pancreatic cancer cell lines

scientific article

Improvement of L-dopa absorption by dipeptidyl derivation, utilizing peptide transporter PepT1.

scientific article published in December 1998

In vivo evidence of organic cation transporter-mediated tracheal accumulation of the anticholinergic agent ipratropium in mice

scientific article published on 19 May 2013

In-vitro evidence of enhanced breast cancer resistance protein-mediated intestinal urate secretion by uremic toxins in Caco-2 cells.

scientific article published on 17 December 2014

Intestinal absorption of HMG-CoA reductase inhibitor pitavastatin mediated by organic anion transporting polypeptide and P-glycoprotein/multidrug resistance 1.

scientific article published on 27 December 2010

Intestinal absorption of HMG-CoA reductase inhibitor pravastatin mediated by organic anion transporting polypeptide

scientific article published on 5 August 2010

Involvement of Concentrative Nucleoside Transporter 1 in Intestinal Absorption of Trifluridine Using Human Small Intestinal Epithelial Cells

scientific article

Involvement of OCTN1 (SLC22A4) in pH-dependent transport of organic cations.

scientific article

Kinetic Evaluation of Determinant Factors for Cellular Accumulation of Protoporphyrin IX Induced by External 5-Aminolevulinic Acid for Photodynamic Cancer Therapy

scientific article published on 8 May 2015

Kinetic analyses of trans-1-amino-3-[18F]fluorocyclobutanecarboxylic acid transport in Xenopus laevis oocytes expressing human ASCT2 and SNAT2.

scientific article published on 3 May 2013

Local Drug-Drug Interaction of Donepezil with Cilostazol at Breast Cancer Resistance Protein (ABCG2) Increases Drug Accumulation in Heart.

scientific article published on 14 October 2015

Long-lasting inhibitory effect of apple and orange juices, but not grapefruit juice, on OATP2B1-mediated drug absorption

scientific article

Major active components in grapefruit, orange, and apple juices responsible for OATP2B1-mediated drug interactions

scientific article published on 21 June 2013

Major active components in grapefruit, orange, and apple juices responsible for OATP2B1-mediated drug interactions

scientific article published on 6 November 2012

Mathematical modeling of the in vitro hepatic disposition of mycophenolic acid and its glucuronide in sandwich-cultured human hepatocytes

scientific article published on 13 December 2013

Methods to Discover Alternative Promoter Usage and Transcriptional Regulation of Murine Bcrp1.

scientific article published on 27 May 2016

Methods to evaluate transporter activity in cancer

scientific article published on January 2010

Modeling approach for multiple transporters-mediated drug-drug interactions in sandwich-cultured human hepatocytes: effect of cyclosporin A on hepatic disposition of mycophenolic acid phenyl-glucuronide.

scientific article published on 14 November 2014

Molecular localization and characterization of multiple binding sites of organic anion transporting polypeptide 2B1 (OATP2B1) as the mechanism for substrate and modulator dependent drug–drug interaction

article

More relevant prediction for in vivo drug interaction of candesartan cilexetil on hepatic bile acid transporter BSEP using sandwich-cultured hepatocytes

scientific article published on 23 July 2013

Na+ - and Cl- -coupled active transport of nitric oxide synthase inhibitors via amino acid transport system B(0,+)

scientific article

Novel 5' untranslated region variants of BCRP mRNA are differentially expressed in drug-selected cancer cells and in normal human tissues: implications for drug resistance, tissue-specific expression, and alternative promoter usage

scientific article published on May 2006

Novel LC-MS/MS method for simultaneous quantification of KW-7158, a new drug candidate for urinary incontinence and bladder hyperactivity, and its metabolites in rat plasma: a pharmacokinetic study in male and female rats

scientific article published on 16 February 2012

OATP transporter-mediated drug absorption and interaction

scientific article

OATP2A1/SLCO2A1-mediated prostaglandin E2 loading into intracellular acidic compartments of macrophages contributes to exocytotic secretion

scientific article published on 13 October 2015

Organic Anion Transporting Polypeptide (OATP)2B1 Contributes to Gastrointestinal Toxicity of Anticancer Drug SN-38, Active Metabolite of Irinotecan Hydrochloride.

scientific article published on 2 November 2015

Organic anion transporting polypeptide 2B1 expression correlates with uptake of estrone-3-sulfate and cell proliferation in estrogen receptor-positive breast cancer cells.

scientific article

Organic cation transporter-mediated renal secretion of ipratropium and tiotropium in rats and humans.

scientific article

Oxaliplatin transport mediated by organic cation/carnitine transporters OCTN1 and OCTN2 in overexpressing human embryonic kidney 293 cells and rat dorsal root ganglion neurons.

scientific article published on 23 May 2011

Plasma pharmacokinetics and tissue distribution of the breast cancer resistance protein (BCRP/ABCG2) inhibitor fumitremorgin C in SCID mice bearing T8 tumors.

scientific article published on October 2004

Preclinical studies of vorinostat (suberoylanilide hydroxamic acid) combined with cytosine arabinoside and etoposide for treatment of acute leukemias

scientific article published on 17 February 2009

Prostaglandin Transporter OATP2A1/SLCO2A1 Is Essential for Body Temperature Regulation during Fever

scientific article published on 21 May 2018

Prostaglandin transporter (OATP2A1/SLCO2A1) contributes to local disposition of eicosapentaenoic acid-derived PGE3

scientific article published on 10 December 2015

Putative roles of organic anion transporting polypeptides (OATPs) in cell survival and progression of human cancers

scientific article

Putative transport mechanism and intracellular fate of trans-1-amino-3-18F-fluorocyclobutanecarboxylic acid in human prostate cancer

scientific article

Quantitative time-lapse imaging-based analysis of drug-drug interaction mediated by hepatobiliary transporter, multidrug resistance-associated protein 2, in sandwich-cultured rat hepatocytes.

scientific article

Renal secretion of uric acid by organic anion transporter 2 (OAT2/SLC22A7) in human.

scientific article

Role of OATP2A1 in PGE(2) secretion from human colorectal cancer cells via exocytosis in response to oxidative stress

scientific article published on 2 February 2016

Roles of Organic Anion Transporting Polypeptide 2A1 (OATP2A1/SLCO2A1) in Regulating the Pathophysiological Actions of Prostaglandins.

scientific article published on 4 December 2017

SGLT2 inhibitor lowers serum uric acid through alteration of uric acid transport activity in renal tubule by increased glycosuria

scientific article

Saturable Hepatic Extraction of Gemcitabine Involves Biphasic Uptake Mediated by Nucleoside Transporters Equilibrative Nucleoside Transporter 1 and 2.

scientific article published on 2 June 2015

Significance of water solubility in the gastrointestinal absorption of trans-bis(n-valerato)(1 R,2R-cyclohexanediamine)(oxalato)platinum(IV), an orally active antitumor platinum complex, and its analogs

scientific article published on 01 February 1998

Solute carrier transporters as targets for drug delivery and pharmacological intervention for chemotherapy

scientific article published on 31 May 2011

Species difference in the effect of grapefruit juice on intestinal absorption of talinolol between human and rat.

scientific article published on 24 September 2009

Species differences in the pharmacokinetics of KW-7158 [(2S)-(+)-3,3,3-Trifluoro-2-hydroxy-2-methyl-N-(5,5,10-trioxo-4,10-dihydrothieno[3,2-c][1]benzothiepin-9-yl)propanamide]: formation of hydrolyzed metabolite in human and animals.

scientific article published on 10 February 2012

Structure and function of ATA3, a new subtype of amino acid transport system A, primarily expressed in the liver and skeletal muscle

scientific journal article

Substrate- and dose-dependent drug interactions with grapefruit juice caused by multiple binding sites on OATP2B1.

scientific article

The ErbB3-binding protein Ebp1 suppresses androgen receptor-mediated gene transcription and tumorigenesis of prostate cancer cells.

scientific article

The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme

scientific article published on 24 March 2004

Total syntheses of (-)- and (+)-goniomitine.

scientific article published on 4 March 2011

Transport characteristics of L-citrulline in renal apical membrane of proximal tubular cells.

scientific article

Transport mechanisms of hepatic uptake and bile excretion in clinical hepatobiliary scintigraphy with 99mTc-N-pyridoxyl-5-methyltryptophan

scientific article published on 13 January 2014

Uric acid analogue as a possible xenobiotic marker of uric acid transporter Urat1 in rats

scientific article published on 27 December 2018

Usefulness of kidney slices for functional analysis of apical reabsorptive transporters

scientific article published on 9 October 2017

[(14)C]Fluciclovine (alias anti-[(14)C]FACBC) uptake and ASCT2 expression in castration-resistant prostate cancer cells

scientific article published on 15 July 2015

List of works by Takeo Nakanishi

A new orally active antitumor 1 R ,2 R -cyclohexanediamine-platinum(IV) complex: trans -( n -valerato)chloro(1 R ,2 R -cyclohexanediamine) (oxalato)platinum(IV)

A novel role for OATP2A1/SLCO2A1 in a murine model of colon cancer

A novel xenobiotic responsive element regulated by aryl hydrocarbon receptor is involved in the induction of BCRP/ABCG2 in LS174T cells.

A role of prostaglandin transporter in regulating PGE₂ release from human bronchial epithelial BEAS-2B cells in response to LPS.

Accumulation of trans-1-amino-3-[(18)F]fluorocyclobutanecarboxylic acid in prostate cancer due to androgen-induced expression of amino acid transporters

Active intestinal absorption of fluoroquinolone antibacterial agent ciprofloxacin by organic anion transporting polypeptide, Oatp1a5.

An orally active antitumor cyclohexanediamine-Pt(IV) complex

Analysis of the Metabolic Pathway of Bosentan and of the Cytotoxicity of Bosentan Metabolites Based on a Quantitative Modeling of Metabolism and Transport in Sandwich-Cultured Human Hepatocytes.

Apple-derived Nanoparticles Modulate Expression of Organic-Anion-Transporting Polypeptide (OATP) 2B1 in Caco-2 Cells

Application of quantitative time-lapse imaging (QTLI) for evaluation of Mrp2-based drug-drug interaction induced by liver metabolites.

Association of miR-145 With Statin-Induced Skeletal Muscle Toxicity in Human Rhabdomyosarcoma RD Cells

Bcrp1 transcription in mouse testis is controlled by a promoter upstream of a novel first exon (E1U) regulated by steroidogenic factor-1

Breast cancer resistance protein (BCRP/ABCG2): its role in multidrug resistance and regulation of its gene expression.

Breast cancer resistance protein (BCRP/MXR/ABCG2) in acute myeloid leukemia: discordance between expression and function

Breast cancer resistance protein (BCRP/MXR/ABCG2) in adult acute lymphoblastic leukaemia: frequent expression and possible correlation with shorter disease-free survival

Cancer cell-targeted drug delivery utilizing oligopeptide transport activity

Cancer cell-targeted drug delivery utilizing oligopeptide transport activity.

Cancer cells uptake porphyrinsviaheme carrier protein 1

Carnitine precursor γ-butyrobetaine is a novel substrate of the Na(+)- and Cl(-)-dependent GABA transporter Gat2.

Carrier-Mediated Prodrug Uptake to Improve the Oral Bioavailability of Polar Drugs: An Application to an Oseltamivir Analogue

Characteristics of transcription-regulatory elements for gene expression from plasmid vectors in human trophoblast cell lines

Co-localization of microsomal prostaglandin E synthase-1 with cyclooxygenase-1 in layer II of murine placental syncytiotrophoblasts.

Comparison of transgene expression mediated by several Fiber-modified adenovirus vectors in trophoblast cells

Contribution of Equilibrative Nucleoside Transporters 1 and 2 to Gemcitabine Uptake in Pancreatic Cancer Cells.

Contribution of equilibrative nucleoside transporter(s) to intestinal basolateral and apical transports of anticancer trifluridine.

Current Progress Toward a Better Understanding of Drug Disposition Within the Lungs: Summary Proceedings of the First Workshop on Drug Transporters in the Lungs.

Different Involvement of OAT in Renal Disposition of Oral Anticoagulants Rivaroxaban, Dabigatran, and Apixaban.

Differential Effect of Grapefruit Juice on Intestinal Absorption of Statins Due to Inhibition of Organic Anion Transporting Polypeptide and/or P-glycoprotein

Direct evidence for peptide transporter (PepT1)-mediated uptake of a nonpeptide prodrug, valacyclovir

Drug efflux by breast cancer resistance protein is a mechanism of resistance to the benzimidazole insulin-like growth factor receptor/insulin receptor inhibitor, BMS-536924

Effect of back pressure on emulsification of lipid nanodispersions in a high-pressure homogenizer

Effect of tyrosine kinase inhibitors on renal handling of creatinine by MATE1.

Experimental Evidence for Resecretion of PGE2 across Rat Alveolar Epithelium by OATP2A1/SLCO2A1-Mediated Transcellular Transport

Functional Characterization of Apical Transporters Expressed in Rat Proximal Tubular Cells (PTCs) in Primary Culture

Functional characterization of human breast cancer resistance protein (BCRP, ABCG2) expressed in the oocytes of Xenopus laevis

Functional cooperation of SMCTs and URAT1 for renal reabsorption transport of urate

Functional cooperation of URAT1 (SLC22A12) and URATv1 (SLC2A9) in renal reabsorption of urate

Functional cyclic AMP response element in the breast cancer resistance protein (BCRP/ABCG2) promoter modulates epidermal growth factor receptor pathway- or androgen withdrawal-mediated BCRP/ABCG2 transcription in human cancer cells.

Functional pleiotropy of organic anion transporting polypeptide OATP2B1 due to multiple binding sites

Genetic polymorphisms of OATP transporters and their impact on intestinal absorption and hepatic disposition of drugs.

Hepatic uptake of gamma-butyrobetaine, a precursor of carnitine biosynthesis, in rats.

How does whisky lower serum urate level?

Identification and characterization of the major alternative promoter regulating Bcrp1/Abcg2 expression in the mouse intestine

Identification and functional characterization of uric acid transporter Urat1 (Slc22a12) in rats

Identification of MRP2 as a targetable factor limiting oxaliplatin accumulation and response in gastrointestinal cancer

Identification of the Uptake Transporter Responsible for Distribution of Acotiamide into Stomach Tissue

Immunolocalization and pharmacological relevance of oligopeptide transporter PepT1 in intestinal absorption of beta-lactam antibiotics

Impact of FDA-Approved Drugs on the Prostaglandin Transporter OATP2A1/SLCO2A1.

Impact of breast cancer resistance protein expression on the in vitro efficacy of anticancer drugs in pancreatic cancer cell lines

Improvement of L-dopa absorption by dipeptidyl derivation, utilizing peptide transporter PepT1.

In vivo evidence of organic cation transporter-mediated tracheal accumulation of the anticholinergic agent ipratropium in mice

In-vitro evidence of enhanced breast cancer resistance protein-mediated intestinal urate secretion by uremic toxins in Caco-2 cells.

Intestinal absorption of HMG-CoA reductase inhibitor pitavastatin mediated by organic anion transporting polypeptide and P-glycoprotein/multidrug resistance 1.

Intestinal absorption of HMG-CoA reductase inhibitor pravastatin mediated by organic anion transporting polypeptide

Involvement of Concentrative Nucleoside Transporter 1 in Intestinal Absorption of Trifluridine Using Human Small Intestinal Epithelial Cells

Involvement of OCTN1 (SLC22A4) in pH-dependent transport of organic cations.

Kinetic Evaluation of Determinant Factors for Cellular Accumulation of Protoporphyrin IX Induced by External 5-Aminolevulinic Acid for Photodynamic Cancer Therapy

Kinetic analyses of trans-1-amino-3-[18F]fluorocyclobutanecarboxylic acid transport in Xenopus laevis oocytes expressing human ASCT2 and SNAT2.

Local Drug-Drug Interaction of Donepezil with Cilostazol at Breast Cancer Resistance Protein (ABCG2) Increases Drug Accumulation in Heart.

Long-lasting inhibitory effect of apple and orange juices, but not grapefruit juice, on OATP2B1-mediated drug absorption

Major active components in grapefruit, orange, and apple juices responsible for OATP2B1-mediated drug interactions

Major active components in grapefruit, orange, and apple juices responsible for OATP2B1-mediated drug interactions

Mathematical modeling of the in vitro hepatic disposition of mycophenolic acid and its glucuronide in sandwich-cultured human hepatocytes

Methods to Discover Alternative Promoter Usage and Transcriptional Regulation of Murine Bcrp1.

Methods to evaluate transporter activity in cancer

Modeling approach for multiple transporters-mediated drug-drug interactions in sandwich-cultured human hepatocytes: effect of cyclosporin A on hepatic disposition of mycophenolic acid phenyl-glucuronide.

Molecular localization and characterization of multiple binding sites of organic anion transporting polypeptide 2B1 (OATP2B1) as the mechanism for substrate and modulator dependent drug–drug interaction

More relevant prediction for in vivo drug interaction of candesartan cilexetil on hepatic bile acid transporter BSEP using sandwich-cultured hepatocytes

Na+ - and Cl- -coupled active transport of nitric oxide synthase inhibitors via amino acid transport system B(0,+)

Novel 5' untranslated region variants of BCRP mRNA are differentially expressed in drug-selected cancer cells and in normal human tissues: implications for drug resistance, tissue-specific expression, and alternative promoter usage

Novel LC-MS/MS method for simultaneous quantification of KW-7158, a new drug candidate for urinary incontinence and bladder hyperactivity, and its metabolites in rat plasma: a pharmacokinetic study in male and female rats

OATP transporter-mediated drug absorption and interaction

OATP2A1/SLCO2A1-mediated prostaglandin E2 loading into intracellular acidic compartments of macrophages contributes to exocytotic secretion

Organic Anion Transporting Polypeptide (OATP)2B1 Contributes to Gastrointestinal Toxicity of Anticancer Drug SN-38, Active Metabolite of Irinotecan Hydrochloride.

Organic anion transporting polypeptide 2B1 expression correlates with uptake of estrone-3-sulfate and cell proliferation in estrogen receptor-positive breast cancer cells.

Organic cation transporter-mediated renal secretion of ipratropium and tiotropium in rats and humans.

Oxaliplatin transport mediated by organic cation/carnitine transporters OCTN1 and OCTN2 in overexpressing human embryonic kidney 293 cells and rat dorsal root ganglion neurons.

Plasma pharmacokinetics and tissue distribution of the breast cancer resistance protein (BCRP/ABCG2) inhibitor fumitremorgin C in SCID mice bearing T8 tumors.

Preclinical studies of vorinostat (suberoylanilide hydroxamic acid) combined with cytosine arabinoside and etoposide for treatment of acute leukemias