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List of works by Claudia Lukas

53BP1 fosters fidelity of homology-directed DNA repair

scientific article published on 27 June 2016

53BP1 nuclear bodies enforce replication timing at under-replicated DNA to limit heritable DNA damage

scientific article published on 25 February 2019

53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

scientific article published on 13 February 2011

A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression

scientific article

ATR prohibits replication catastrophe by preventing global exhaustion of RPA.

scientific article

Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex

scientific article

Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase

scientific article

Checking on DNA damage in S phase

scientific article published in October 2004

Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway

scientific article published on 23 July 2006

Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation

scientific article

DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks

scientific article

Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation

scientific article (publication date: April 2002)

Deregulation of the RB pathway in human testicular germ cell tumours ⬇️

scientific article published on June 1, 2003

Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage

scientific article

Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1

scientific article

Ectopic expression of RNF168 and 53BP1 increases mutagenic but not physiological non-homologous end joining

scientific article published on 27 April 2015

HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

scientific article

Human CtIP promotes DNA end resection

scientific article

Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks

scientific article

Imaging of protein movement induced by chromosomal breakage: tiny 'local' lesions pose great 'global' challenges

scientific article

Inhibition of Chk1 by CEP-3891 accelerates mitotic nuclear fragmentation in response to ionizing Radiation.

scientific article

Integrating proteomic and functional genomic technologies in discovery-driven translational breast cancer research

scientific article

LEDGF (p75) promotes DNA-end resection and homologous recombination

scientific article

Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks

scientific article published on December 2016

Mammalian cell cycle checkpoints: signalling pathways and their organization in space and time

scientific article published in August 2004

Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention

scientific article

Molecular biology. Shielding broken DNA for a quick fix.

scientific article published in February 2013

More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance

scientific article published on 03 October 2011

Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis

scientific article

Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1

scientific article published on 11 November 2011

Profiling DNA damage response following mitotic perturbations

scientific article published on 15 December 2016

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

scientific article

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

scientific article

Rapid destruction of human Cdc25A in response to DNA damage

scientific journal article

Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks

scientific article (publication date: 24 April 2006)

TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes

scientific article

The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage

scientific article published on 27 July 2014

The chromatin scaffold protein SAFB1 renders chromatin permissive for DNA damage signaling

scientific article published on 19 September 2013

The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage

scientific article

The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases

scientific article published on 24 April 2013

The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator

scientific article

The regulatory landscape of the human HPF1- and ARH3-dependent ADP-ribosylome

scientific article published on 08 October 2021

Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage

scientific article

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