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List of works by Paul J. Tesar

Accessing naïve human pluripotency

scientific article

Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination

scientific article published in Nature

An ES-like pluripotent state in FGF-dependent murine iPS cells

scientific article (publication date: 2010)

CHD7 functions in the nucleolus as a positive regulator of ribosomal RNA biogenesis

scientific article

CHD7 targets active gene enhancer elements to modulate ES cell-specific gene expression

scientific article

Characterizing medullary and human mesenchymal stem cell-derived adipocytes

scientific article published on 01 June 2006

Chemical Screening Identifies Enhancers of Mutant Oligodendrocyte Survival and Unmasks a Distinct Pathological Phase in Pelizaeus-Merzbacher Disease

scientific article published on 23 August 2018

Clemastine fumarate for promotion of optic nerve remyelination

scientific article published on 10 October 2017

Concise Review: Stem Cell-Based Treatment of Pelizaeus-Merzbacher Disease.

scientific article

Conserved and divergent roles of FGF signaling in mouse epiblast stem cells and human embryonic stem cells

scientific article published in March 2010

DNA and chromatin modification networks distinguish stem cell pluripotent ground states.

scientific article

Depletion of Olig2 in oligodendrocyte progenitor cells infected by Theiler's murine encephalomyelitis virus

scientific article published on 2 December 2015

Derivation of germ-line-competent embryonic stem cell lines from preblastocyst mouse embryos.

scientific article

Derivation of naive human embryonic stem cells.

scientific article published on 12 March 2014

Developing therapeutic strategies to promote myelin repair in multiple sclerosis

scientific article published on 20 June 2019

Direct and indirect contribution of human embryonic stem cell-derived hepatocyte-like cells to liver repair in mice.

scientific article

Diverse Chemical Scaffolds Enhance Oligodendrocyte Formation by Inhibiting CYP51, TM7SF2, or EBP

scientific article published on 14 February 2019

Drug screening for human genetic diseases using iPSC models

scientific article published on 01 August 2018

Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo

scientific article

Dysregulated Glial Differentiation in Schizophrenia May Be Relieved by Suppression of SMAD4- and REST-Dependent Signaling

scientific article published on 01 June 2019

ELF5-enforced transcriptional networks define an epigenetically regulated trophoblast stem cell compartment in the human placenta

scientific article published on 30 March 2010

Epigenomic comparison reveals activation of "seed" enhancers during transition from naive to primed pluripotency

scientific article

Epigenomic enhancer profiling defines a signature of colon cancer

scientific article

Generation and characterization of epiblast stem cells from blastocyst-stage mouse embryos.

scientific article published on January 2013

Genetic factors on mouse chromosome 18 affecting susceptibility to testicular germ cell tumors and permissiveness to embryonic stem cell derivation

scientific article published on 24 November 2009

High Throughput and High Content Screening Capabilities of the University of Cincinnati Drug Discovery Center.

scientific article published in May 2013

Human iPSC Glial Mouse Chimeras Reveal Glial Contributions to Schizophrenia

scientific article

Identification and characterization of cell type-specific and ubiquitous chromatin regulatory structures in the human genome

scientific article

Induction of myelinating oligodendrocytes in human cortical spheroids.

scientific article published on 25 July 2018

Isolation and maintenance of mouse epiblast stem cells

scientific article published on 01 January 2010

Isolation of epiblast stem cells from preimplantation mouse embryos.

scientific article

Lgr5 Marks Post-Mitotic, Lineage Restricted Cerebellar Granule Neurons during Postnatal Development.

scientific article

Lower Dopamine D2 Receptor Expression Levels in Human Dopaminergic Neurons Derived From Opioid-Dependent iPSCs

scientific article published on April 2016

Modeling the Mutational and Phenotypic Landscapes of Pelizaeus-Merzbacher Disease with Human iPSC-Derived Oligodendrocytes

scientific article

NG2 expression in NG2 glia is regulated by binding of SoxE and bHLH transcription factors to a Cspg4 intronic enhancer

article

NPTX1 regulates neural lineage specification from human pluripotent stem cells

scientific article published on 13 February 2014

Oligodendrocyte Intrinsic miR-27a Controls Myelination and Remyelination

scientific article published on 01 October 2019

Physiological genomics identifies genetic modifiers of long QT syndrome type 2 severity

scientific article published on 12 February 2018

Preferential Iron Trafficking Characterizes Glioblastoma Stem-like Cells

scientific article

Rapid and robust generation of functional oligodendrocyte progenitor cells from epiblast stem cells

scientific article published on 25 September 2011

Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells

scientific article published in Nature Communications

Retinal pigmented epithelial cells obtained from human induced pluripotent stem cells possess functional visual cycle enzymes in vitro and in vivo.

scientific article published on 15 October 2013

Snapshots of Pluripotency

scientific article

Stem cells: Cloning advance calls for careful regulation

scientific article published on 5 October 2011

StemCellDB: The Human Pluripotent Stem Cell Database at the National Institutes of Health ⬇️

scientific article published on September 26, 2012

Suppression of proteolipid protein rescues Pelizaeus-Merzbacher disease

scientific article published on 01 July 2020

The Chromatin Environment Around Interneuron Genes in Oligodendrocyte Precursor Cells and Their Potential for Interneuron Reprograming

scientific article published on 08 August 2019

Tracking down the human myelinating cell

scientific article published on 13 October 2011

Transcription Elongation Factor Tcea3 Regulates the Pluripotent Differentiation Potential of Mouse Embryonic Stem Cells Via the Lefty1-Nodal-Smad2 Pathway ⬇️

scientific article published on February 1, 2013

Transcription elongation factors represent in vivo cancer dependencies in glioblastoma

scientific article

Transcription factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells.

scientific article

Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells

scientific journal article

Transcriptome-Wide Analyses of Human Neonatal Articular Cartilage and Human Mesenchymal Stem Cell-Derived Cartilage Provide a New Molecular Target for Evaluating Engineered Cartilage

scientific article published on 10 June 2017

Transgenerational epigenetic effects of theApobec1cytidine deaminase deficiency on testicular germ cell tumor susceptibility and embryonic viability ⬇️

scientific article published on August 24, 2012

Using iPSC-derived human DA neurons from opioid-dependent subjects to study dopamine dynamics

scientific article published on 25 May 2016

iPSC Reprogramming Is Not Just an Open and Shut Case

scientific article published in December 2017

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