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List of works by Piero Picci

153Samarium-EDTMP administration followed by hematopoietic stem cell support for bone metastases in osteosarcoma patients

scientific article published on 21 November 2011

1q gain and CDT2 overexpression underlie an aggressive and highly proliferative form of Ewing sarcoma

scientific article

4-Demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin (PNU-159548): a promising new candidate for chemotherapeutic treatment of osteosarcoma patients.

scientific article published on September 2005

A Genome-Wide Scan Identifies Variants in NFIB Associated with Metastasis in Patients with Osteosarcoma

scientific article

A Quinoline-Based DNA Methyltransferase Inhibitor as a Possible Adjuvant in Osteosarcoma Therapy

scientific article published on 29 June 2018

A phase II trial of sorafenib in relapsed and unresectable high-grade osteosarcoma after failure of standard multimodal therapy: an Italian Sarcoma Group study ⬇️

scientific article published on April 28, 2011

Adhesion molecules in high-grade soft tissue sarcomas: correlation to clinical outcome

scientific article published on 01 March 1998

Adjuvant and neo-adjuvant chemotherapy for Ewing's sarcoma family tumors and osteosarcoma of the extremity: further outcome for patients event-free survivors 5 years from the beginning of treatment

scientific article published on 24 October 2007

Adjuvant and neoadjuvant chemotherapy for Ewing sarcoma family tumors in patients aged between 40 and 60: report of 35 cases and comparison of results with 586 younger patients treated with the same protocols in the same years

scientific article published on 01 February 2007

Adjuvant and neoadjuvant chemotherapy for osteosarcoma of the extremities: 27 year experience at Rizzoli Institute, Italy

article

Adriamycin-methotrexate high dose versus adriamycin-methotrexate moderate dose as adjuvant chemotherapy for osteosarcoma of the extremities: a randomized study

scientific article published on 01 November 1986

Advances in emerging drugs for osteosarcoma

scientific article published on 28 May 2015

Alpha-tocopheryl succinate alters cell cycle distribution sensitising human osteosarcoma cells to methotrexate-induced apoptosis

scientific article published on February 2006

Alpha-tocopheryl succinate induces cytostasis and apoptosis in osteosarcoma cells: the role of E2F1.

scientific article

Altered G1 phase regulation in osteosarcoma

scientific article published on 01 October 1997

Alveolar soft part sarcoma

scientific article published on 01 May 1996

An aza-macrocycle containing maltolic side-arms (maltonis) as potential drug against human pediatric sarcomas.

scientific article

Analysis of SAS gene and CDK4 and MDM2 proteins in low-grade osteosarcoma.

scientific article published in January 1999

Analysis of dihydrofolate reductase and reduced folate carrier gene status in relation to methotrexate resistance in osteosarcoma cells

scientific article published on January 2004

Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types

journal article published in 2015

Aneurysmal bone cyst of the mobile spine: report on 41 cases

scientific article

Antitumor activity of the insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 in musculoskeletal tumors.

scientific article

Array comparative genomic hybridization reveals frequent alterations of G1/S checkpoint genes in undifferentiated pleomorphic sarcoma of bone

scientific article published on 19 January 2011

Benefits and adverse events in younger versus older patients receiving neoadjuvant chemotherapy for osteosarcoma: findings from a meta-analysis

scientific article

Biological indicators of prognosis in Ewing's sarcoma: an emerging role for lectin galactoside-binding soluble 3 binding protein (LGALS3BP).

scientific article

Bisphosphonate treatment of aggressive primary, recurrent and metastatic Giant Cell Tumour of Bone.

scientific article

Bone marrow biopsy in the initial staging of Ewing sarcoma: Experience from a single institution

scientific article published on 05 February 2019

Bone metastases in osteosarcoma patients treated with neoadjuvant or adjuvant chemotherapy: the Rizzoli experience in 52 patients

scientific article published on 01 December 2006

C-kit receptor expression in Ewing's sarcoma: lack of prognostic value but therapeutic targeting opportunities in appropriate conditions.

scientific article published in May 2003

CD99 acts as an oncosuppressor in osteosarcoma

scientific article

CD99 drives terminal differentiation of osteosarcoma cells by acting as a spatial regulator of ERK 1/2.

scientific article

CD99 inhibits neural differentiation of human Ewing sarcoma cells and thereby contributes to oncogenesis

scientific article

CD99 isoforms dictate opposite functions in tumour malignancy and metastases by activating or repressing c-Src kinase activity.

scientific article published on 30 April 2007

CD99 suppresses osteosarcoma cell migration through inhibition of ROCK2 activity.

scientific article published on 6 May 2013

CD99 triggering in Ewing sarcoma delivers a lethal signal through p53 pathway reactivation and cooperates with doxorubicin

scientific article published on 11 December 2014

CIC-DUX4fusion-positive round-cell sarcomas of soft tissue and bone: a single-institution morphological and molecular analysis of seven cases

Candidate germline polymorphisms of genes belonging to the pathways of four drugs used in osteosarcoma standard chemotherapy associated with risk, survival and toxicity in non-metastatic high-grade osteosarcoma

scientific article published on 22 August 2016

Canine tumor cross-species genomics uncovers targets linked to osteosarcoma progression

scientific article

Case report 301. Diagnosis: dedifferentiated chondrosarcoma of the upper end of the humerus

scientific article published on 01 January 1985

Case report 437: Solitary (unicameral, simple) bone cyst of the scapula

scientific article published on 01 January 1987

Case report 489

scientific article published on 01 January 1988

Case report 489: Hibernoma of left thigh

scientific article published on 01 January 1988

Case report 517. Mesenchymal chondrosarcoma of the femur

scientific article published on 01 January 1989

Case report 629: Osseous hydatidosis

scientific article published on 01 January 1990

Caveolin-1 reduces osteosarcoma metastases by inhibiting c-Src activity and met signaling.

scientific article published on August 2007

Centrosome abnormalities in giant cell tumour of bone: possible association with chromosomal instability

scientific article published on 08 January 2010

Changes in p14(ARF) do not play a primary role in human chondrosarcoma tissues

scientific article published in September 2001

Changes of the p16 gene but not the p53 gene in human chondrosarcoma tissues

scientific article published on 01 March 2000

Chondrosarcoma of the mobile spine: report on 22 cases

scientific article

Chordoma of the mobile spine and sacrum: a retrospective analysis of a series of patients surgically treated at two referral centers

scientific article

Chordoma of the mobile spine: fifty years of experience

scientific article

Clear cell chondrosarcoma of bone. A report of 8 cases

scientific article published on 01 January 1991

Clinical Significance of Tumor Protein D52 Immunostaining in a Large Series of Ewing's Sarcoma Family of Tumors

scientific article published on 21 February 2011

Clinical correlations of genetic changes by comparative genomic hybridization in Ewing sarcoma and related tumors

scientific article published on 01 October 1999

Clinical impact of the methotrexate resistance-associated genes C-MYC and dihydrofolate reductase (DHFR) in high-grade osteosarcoma.

scientific article

Clinical outcome of central conventional chondrosarcoma

scientific article published on 30 May 2012

Clinicopathological significance of cell cycle regulation markers in a large series of genetically confirmed Ewing's Sarcoma Family of Tumors

scientific article published on 01 March 2011

Combined use of expression and CGH arrays pinpoints novel candidate genes in Ewing sarcoma family of tumors

scientific article published on 14 January 2009

Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma

scientific article (publication date: 12 February 2012)

Comparison of the outcome of conventional osteosarcoma at two specialist international orthopaedic oncology centres

scientific article published on January 2004

Contribution of MEK/MAPK and PI3-K signaling pathway to the malignant behavior of Ewing's sarcoma cells: therapeutic prospects

scientific article published on January 2004

Copy number alterations and neoplasia-specific mutations in MELK, PDCD1LG2, TLN1, and PAX5 at 9p in different neoplasias

scientific article published on 24 March 2014

Correlation between apoptosis and TP53 status in osteosarcoma

scientific article published on 01 September 1998

Corrigendum: Positively selected enhancer elements endow osteosarcoma cells with metastatic competence

scientific article published on 01 April 2018

DNA copy number amplifications in sarcomas with homogeneously staining regions and double minutes

scientific article published on 01 April 2001

Detection of circulating tumor cells in liquid biopsy from Ewing sarcoma patients.

scientific article published on 9 January 2018

Diagnostic utility of molecular investigation in extraskeletal myxoid chondrosarcoma

scientific article published on 07 February 2014

Differential gene expression in classic giant cell tumours of bone: Tenascin C as biological risk factor for local relapses and metastases.

scientific article published in July 2010

Difficulty distinguishing benign notochordal cell tumor from chordoma further suggests a link between them

scientific article

Effect of TP53 Arg72Pro and MDM2 SNP309 polymorphisms on the risk of high-grade osteosarcoma development and survival

scientific article published in May 2009

Efficacy of and resistance to anti-IGF-1R therapies in Ewing's sarcoma is dependent on insulin receptor signaling

scientific article published on 31 January 2011

Elevated TNFR1 and serotonin in bone metastasis are correlated with poor survival following bone metastasis diagnosis for both carcinoma and sarcoma primary tumors

scientific article

Emerging drugs for high-grade osteosarcoma

scientific article published on 09 August 2010

Enchondroma vs. chondrosarcoma: a simple, easy-to-use, new magnetic resonance sign

scientific article

Epidermal growth factor receptor signalling contributes to osteoblastic stromal cell proliferation, osteoclastogenesis and disease progression in giant cell tumour of bone.

scientific article

Epithelial cell adhesion molecules and epithelial mesenchymal transition (EMT) markers in Ewing's sarcoma family of tumors (ESFTs). Do they offer any prognostic significance?

scientific article published on 17 August 2012

Epithelial marker expression does not rule out a diagnosis of Ewing's sarcoma family of tumours

scientific article published on 02 September 2011

Evaluation of the molecular mechanisms involved in the gain of function of a Li-Fraumeni TP53 mutation

scientific article published on August 2005

Ewing Sarcoma: Current Management and Future Approaches Through Collaboration

scientific article published on 24 August 2015

Ewing sarcoma in patients over 40 years of age: a prospective analysis of 31 patients treated at a single institution

scientific article published on 18 July 2016

Ewing's sarcoma family tumours. Differences in clinicopathological characteristics at presentation between localised and metastatic tumours

scientific article

Excision repair cross-complementation group 1 protein expression predicts survival in patients with high-grade, non-metastatic osteosarcoma treated with neoadjuvant chemotherapy.

scientific article

Expression of P-glycoprotein in high-grade osteosarcomas in relation to clinical outcome

scientific article published on 01 November 1995

Expression of an IGF-I receptor dominant negative mutant induces apoptosis, inhibits tumorigenesis and enhances chemosensitivity in Ewing's sarcoma cells.

scientific article published on September 2002

Expression of insulin-like growth factor system components in Ewing's sarcoma and their association with survival.

scientific article

Fibrocartilaginous mesenchymoma of bone: a single-institution experience with molecular investigations and a review of the literature

scientific article

Frequent deletion of CDKN2A and recurrent coamplification of KIT, PDGFRA, and KDR in fibrosarcoma of bone--an array comparative genomic hybridization study.

scientific article

From a 16th century monastery to a 21st century orthopaedic hospital

scientific article

Full-lung tomograms and bone scanning in the initial work-up of patients with osteogenic sarcoma. A review of 126 cases

scientific article published on October 1982

Fusion events lead to truncation of FOS in epithelioid hemangioma of bone

scientific article

Galectin-1 (GAL-1) expression is a useful tool to differentiate between small cell osteosarcoma and Ewing sarcoma

scientific article published on 17 May 2013

Gene expression profiling of giant cell tumor of bone reveals downregulation of extracellular matrix components decorin and lumican associated with lung metastasis.

scientific article published on 11 October 2014

Generation of human single-chain antibody to the CD99 cell surface determinant specifically recognizing Ewing's sarcoma tumor cells.

scientific article

Genetic analysis of fibrosarcoma of bone, a rare tumour entity closely related to osteosarcoma and malignant fibrous histiocytoma of bone

article

Genetic characterization of mesenchymal, clear cell, and dedifferentiated chondrosarcoma.

scientific article

Genetic imbalances in 67 synovial sarcomas evaluated by comparative genomic hybridization

scientific article published on 01 November 1998

Genome-wide association study identifies the GLDC/IL33 locus associated with survival of osteosarcoma patients

scientific article published on 6 December 2017

Genome-wide association study identifies two susceptibility loci for osteosarcoma

scientific article (publication date: July 2013)

Genomic imbalances associated with methotrexate resistance in human osteosarcoma cell lines detected by comparative genomic hybridization-based techniques.

scientific article published in September 2003

Giant cell reparative granuloma and other giant cell lesions of the bones of the hands and feet

scientific article published on 01 January 1986

Grade of chemotherapy-induced necrosis as a predictor of local and systemic control in 881 patients with non-metastatic osteosarcoma of the extremities treated with neoadjuvant chemotherapy in a single institution

scientific article published on 01 September 2005

Growth inhibition and sensitization to cisplatin by zoledronic acid in osteosarcoma cells

scientific article published on 20 November 2006

HSPA8 as a novel fusion partner of NR4A3 in extraskeletal myxoid chondrosarcoma

scientific article published on 6 April 2017

High Dose Ifosfamide in Relapsed and Unresectable High-Grade Osteosarcoma Patients: A Retrospective Series

scientific article published on 31 October 2020

High-dose chemotherapy in the treatment of relapsed osteosarcoma: an Italian sarcoma group study

scientific article published in April 2002

High-grade focal areas in low-grade central osteosarcoma: high-grade or still low-grade osteosarcoma?

scientific article published on 29 October 2015

Histologic evaluation of necrosis in osteosarcoma induced by chemotherapy. Regional mapping of viable and nonviable tumor

scientific article published on 01 October 1985

Histological heterogeneity of Ewing's sarcoma/PNET: an immunohistochemical analysis of 415 genetically confirmed cases with clinical support

scientific article published on 17 October 2009

Histologically verified lung metastases in benign giant cell tumours--14 cases from a single institution.

scientific article

Histone 3.3 mutations in giant cell tumor and giant cell-rich sarcomas of bone.

scientific article published on 9 September 2017

Histotype-tailored neoadjuvant chemotherapy versus standard chemotherapy in patients with high-risk soft-tissue sarcomas (ISG-STS 1001): an international, open-label, randomised, controlled, phase 3, multicentre trial

scientific article

Identification of candidate genes involved in the reversal of malignant phenotype of osteosarcoma cells transfected with the liver/bone/kidney alkaline phosphatase gene.

scientific article published on April 2004

Identification of common and distinctive mechanisms of resistance to different anti-IGF-IR agents in Ewing's sarcoma.

scientific article

Identification of potential biomarkers for giant cell tumor of bone using comparative proteomics analysis.

scientific article

Imaging of bone tumors for the musculoskeletal oncologic surgeon.

scientific article published on 29 December 2011

Immunoreactivity using anti-ERG monoclonal antibodies in sarcomas is influenced by clone selection

scientific article

Immunostaining of the p30/32MIC2 antigen and molecular detection of EWS rearrangements for the diagnosis of Ewing's sarcoma and peripheral neuroectodermal tumor.

scientific article published on April 1996

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

journal article published in 2014

In Ewing's sarcoma CCN3(NOV) inhibits proliferation while promoting migration and invasion of the same cell type

scientific article (publication date: 23 June 2005)

Inferior survival for patients with malignant peripheral nerve sheath tumors defined by aberrant TP53

scientific article published on 26 June 2018

Insulin-like growth factor 2 mRNA-binding protein 3 is a novel post-transcriptional regulator of Ewing sarcoma malignancy

scientific article published on 27 April 2018

Insulin-like growth factor binding protein 3 as an anticancer molecule in Ewing's sarcoma.

scientific article published on September 2006

Integrated approaches to miRNAs target definition: time-series analysis in an osteosarcoma differentiative model.

scientific article published on 30 June 2015

Intracortical osteosarcoma: rare entity or early manifestation of classical osteosarcoma?

scientific article published on 01 January 1983

Intraosseous papillary intralymphatic angioendothelioma (PILA): one new case and review of the literature.

scientific article published on 30 January 2018

Involvement of INK4A gene products in the pathogenesis and development of human osteosarcoma.

scientific article published in December 2001

Italian Cooperative Study for the treatment of children and young adults with localized Ewing sarcoma of bone: a preliminary report of 6 years of experience

article

Late sarcoma development after curettage and bone grafting of benign bone tumors

article

Local recurrence and local control of non-metastatic osteosarcoma of the extremities: a 27-year experience in a single institution

article

Localized Ewing's sarcoma of bone: ten years' experience at the Istituto Ortopedico Rizzoli in 124 cases treated with multimodal therapy

scientific article published on 01 February 1985

Long-term follow-up and post-relapse survival in patients with non-metastatic osteosarcoma of the extremity treated with neoadjuvant chemotherapy.

scientific article published on August 1997

MDM2 and CDK4 expression in periosteal osteosarcoma.

scientific article published on 31 December 2014

MRP1 overexpression determines poor prognosis in prospectively treated patients with localized high-risk soft tissue sarcoma of limbs and trunk wall: an ISG/GEIS study.

scientific article

Malignant fibrous histiocytoma of bone: Analysis of genomic imbalances by comparative genomic hybridisation and C-MYC expression by immunohistochemistry

scientific article published on 19 April 2006

Malignant fibrous histiocytoma: inherited and sporadic forms have loss of heterozygosity at chromosome bands 9p21-22-evidence for a common genetic defect

scientific article published in February 2000

Mapping protein signal pathway interaction in sarcoma bone metastasis: linkage between rank, metalloproteinases turnover and growth factor signaling pathways.

scientific article published on 23 July 2013

Mechanisms of gene amplification and evidence of coamplification in drug-resistant human osteosarcoma cell lines.

scientific article

Metachronous pulmonary metastases resection in patients with Ewing's sarcoma initially treated with adjuvant or neoadjuvant chemotherapy

scientific article published on 01 June 1995

Metformin as an adjuvant drug against pediatric sarcomas: hypoxia limits therapeutic effects of the drug

scientific article (publication date: 2013)

Metformin inhibits growth and sensitizes osteosarcoma cell lines to cisplatin through cell cycle modulation

scientific article published on 20 November 2013

Methylated RASSF1A in malignant peripheral nerve sheath tumors identifies neurofibromatosis type 1 patients with inferior prognosis

scientific article published on 19 July 2014

Molecular diagnosis in Ewing family tumors: the Rizzoli experience--222 consecutive cases in four years

scientific article

Molecular mechanisms of CD99-induced caspase-independent cell death and cell-cell adhesion in Ewing's sarcoma cells: actin and zyxin as key intracellular mediators.

scientific article

Morphological and immunophenotypic features of primary and metastatic giant cell tumour of bone

scientific article published on 15 December 2009

Murine model for skeletal metastases of Ewing's sarcoma

scientific article

NG2 expression predicts the metastasis formation in soft-tissue sarcoma patients

scientific article published on 01 January 2009

NG2/CSPG4-collagen type VI interplays putatively involved in the microenvironmental control of tumour engraftment and local expansion.

scientific article published on 3 April 2013

NVP-BEZ235 as a new therapeutic option for sarcomas.

scientific article

Neoadjuvant chemotherapy for Ewing's sarcoma of bone: no benefit observed after adding ifosfamide and etoposide to vincristine, actinomycin, cyclophosphamide, and doxorubicin in the maintenance phase--results of two sequential studies

scientific article published on 01 March 1998

Neoadjuvant chemotherapy for extremity osteosarcoma--preliminary results of the Rizzoli's 4th study

scientific article published on 01 January 1998

Neoadjuvant chemotherapy for osteosarcoma of the extremities in patients aged 41-60 years: outcome in 34 cases treated with adriamycin, cisplatinum and ifosfamide between 1984 and 1999

scientific article published on 01 June 2007

Neoadjuvant chemotherapy for radioinduced osteosarcoma of the extremity: The Rizzoli experience in 20 cases

Neoadjuvant chemotherapy in malignant fibrous histiocytoma of bone and in osteosarcoma located in the extremities: analogies and differences between the two tumors

scientific article published on 01 November 1997

Neoadjuvant chemotherapy with high-dose Ifosfamide, high-dose methotrexate, cisplatin, and doxorubicin for patients with localized osteosarcoma of the extremity: a joint study by the Italian and Scandinavian Sarcoma Groups.

scientific article

Neoadjuvant chemotherapy with methotrexate, cisplatin, and doxorubicin with or without ifosfamide in nonmetastatic osteosarcoma of the extremity: an Italian sarcoma group trial ISG/OS-1.

scientific article

No correlation between methotrexate serum level and histologic response in the pre-operative treatment of extremity osteosarcoma

article

Nonmetastatic Ewing family tumors: high-dose chemotherapy with stem cell rescue in poor responder patients. Results of the Italian Sarcoma Group/Scandinavian Sarcoma Group III protocol

article

Nonmetastatic osteosarcoma of the extremity. Neoadjuvant chemotherapy with methotrexate, cisplatin, doxorubicin and ifosfamide. An Italian Sarcoma Group study (ISG/OS-Oss).

scientific article published on November 2014

Oncogene alterations in primary, recurrent, and metastatic human bone tumors

scientific article published on October 1996

Osteoblastoma-like osteosarcoma: High-grade or low-grade osteosarcoma?

scientific article published on 04 November 2018

Osteoid osteoma and osteoblastoma of the talus. A report of 40 cases

scientific article published in 1986

Osteosarcoma (osteogenic sarcoma).

scientific article

Osteosarcoma of the hands and feet: a distinct clinico-pathological subgroup.

scientific article published on 5 December 2012

Osteosarcoma of the mobile spine.

scientific article published on March 2012

Osteosarcoma of the pelvis: a monoinstitutional experience in patients younger than 41 years

scientific article published in November 2012

Osteosarcoma. Low-grade intraosseous-type osteosarcoma, histologically resembling parosteal osteosarcoma, fibrous dysplasia, and desmoplastic fibroma

scientific article published on 01 January 1993

Outcome of advanced, unresectable conventional central chondrosarcoma.

scientific article published on 3 July 2014

Overcoming glutathione S-transferase P1-related cisplatin resistance in osteosarcoma

scientific article published in August 2008

Overcoming resistance to conventional drugs in Ewing sarcoma and identification of molecular predictors of outcome

scientific article published on 23 March 2009

P-glycoprotein expression in osteosarcoma: a basis for risk-adapted adjuvant chemotherapy.

scientific article

Paediatric chondrosarcomas: a retrospective review of 17 cases

scientific article published on 26 September 2015

Palliative therapy for osteosarcoma.

scientific article published on February 2011

Parosteal osteosarcoma dedifferentiating into telangiectatic osteosarcoma: importance of lytic changes and fluid cavities at imaging

scientific article published on 07 March 2009

Parosteal osteosarcoma: a monocentric retrospective analysis of 195 patients

scientific article published on 23 May 2019

Pattern of relapse in 290 patients with nonmetastatic Ewing's sarcoma family tumors treated at a single institution with adjuvant and neoadjuvant chemotherapy between 1972 and 1999

scientific article published on 18 April 2006

Phenotypic and molecular differences between giant-cell tumour of soft tissue and its bone counterpart.

scientific article

Platelet-derived growth factors enhance proliferation of human stromal stem cells

Positively selected enhancer elements endow osteosarcoma cells with metastatic competence.

scientific article published on 15 January 2018

Postrelapse survival in osteosarcoma of the extremities: prognostic factors for long-term survival

Preclinical Effectiveness of Selective Inhibitor of IRS-1/2 NT157 in Osteosarcoma Cell Lines.

scientific article published on 13 May 2015

Preclinical in vivo study of new insulin-like growth factor-I receptor--specific inhibitor in Ewing's sarcoma

scientific article published on February 2007

Preclinical validation of Aurora kinases-targeting drugs in osteosarcoma

scientific article published on 15 October 2013

Predictive factors of disease-free survival for non-metastatic osteosarcoma of the extremity: an analysis of 300 patients treated at the Rizzoli Institute

scientific article

Predictive factors of histologic response to primary chemotherapy in patients with Ewing sarcoma.

scientific article

Predictive factors of histological response to primary chemotherapy in Ewing's sarcoma

scientific article published in January 1998

Presence and expression of the simian virus-40 genome in human giant cell tumors of bone.

scientific article published in May 2000

Presence of telomerase activity in different musculoskeletal tumor histotypes and correlation with aggressiveness

scientific article published in May 2001

Primary angiosarcoma of bone: a retrospective analysis of 60 patients from 2 institutions.

scientific article published on December 2014

Primary chemotherapy and delayed surgery (neoadjuvant chemotherapy) for osteosarcoma of the extremities. The Istituto Rizzoli Experience in 127 patients treated preoperatively with intravenous methotrexate (high versus moderate doses) and intraarter

scientific article published on 01 June 1990

Primary chemotherapy and delayed surgery for non-metastatic telangiectatic osteosarcoma of the extremities. Results in 28 patients

scientific article published on 01 January 1994

Primary chemotherapy and delayed surgery for nonmetastatic osteosarcoma of the extremities. Results in 164 patients preoperatively treated with high doses of methotrexate followed by cisplatin and doxorubicin

scientific article published on 01 December 1993

Primary high-grade osteosarcoma: comparison between preadolescent and older patients.

scientific article published in March 2005

Primary metastatic Ewing's family tumors: results of the Italian Sarcoma Group and Scandinavian Sarcoma Group ISG/SSG IV Study including myeloablative chemotherapy and total-lung irradiation

article

Primary pseudomyogenic haemangioendothelioma of bone: report of two cases

scientific article published on 11 October 2014

Prognostic and predictive role of CXCR4, IGF-1R and Ezrin expression in localized synovial sarcoma: is chemotaxis important to tumor response?

scientific article

Prognostic and therapeutic relevance of HER2 expression in osteosarcoma and Ewing's sarcoma

scientific article

Prognostic factors for osteosarcoma of the extremity treated with neoadjuvant chemotherapy: 15-year experience in 789 patients treated at a single institution

scientific article published on 01 March 2006

Prognostic impact of reduced connexin43 expression and gap junction coupling of neoplastic stromal cells in giant cell tumor of bone

scientific article published on May 2015

Prognostic relevance of C-myc gene expression in giant-cell tumor of bone

scientific article published on 01 January 1998

Prognostic relevance of CCN3 in Ewing sarcoma

scientific article

Prognostic role of nuclear factor/IB and bone remodeling proteins in metastatic giant cell tumor of bone: A retrospective study.

scientific article published on 2 April 2015

Prognostic significance of miR-34a in Ewing sarcoma is associated with cyclin D1 and ki-67 expression.

scientific article published on 10 July 2014

Prognostic significance of serum alkaline phosphatase measurements in patients with osteosarcoma treated with adjuvant or neoadjuvant chemotherapy

scientific article published on 01 February 1993

Prognostic value of CCN3 in osteosarcoma

scientific article published on February 2008

Prognostic value of P-glycoprotein in high-grade osteosarcoma.

scientific article published in October 2007

Proteases and interleukin-6 gene analysis in 92 giant cell tumors of bone

scientific article published in March 2004

Proton pump inhibitor chemosensitization in human osteosarcoma: from the bench to the patients' bed

scientific article published on 24 October 2013

Quality of surgery and neoadjuvant combined therapy in the ISG-GEIS trial on soft tissue sarcomas of limbs and trunk wall.

scientific article published on 30 October 2012

Quantification of the heterogeneity of prognostic cellular biomarkers in ewing sarcoma using automated image and random survival forest analysis

scientific article

Radiological features of 24 periosteal chondrosarcomas

scientific article published on 01 April 2001

Radiological study of 12 high-grade surface osteosarcomas

article

Receptor tyrosine kinase pathway analysis sheds light on similarities between clear-cell sarcoma and metastatic melanoma.

scientific article

Recurring osteoblastoma initially presenting as a typical osteoid osteoma. Report of two cases

scientific article published in January 1991

Redundancy of autocrine loops in human osteosarcoma cells.

scientific article published on February 1999

Response to high-dose ifosfamide in patients with advanced/recurrent Ewing sarcoma

scientific article

Reversal of malignant phenotype in human osteosarcoma cells transduced with the alkaline phosphatase gene

scientific article

Risk factors for local recurrences after limb-salvage surgery for high-grade osteosarcoma of the extremities.

scientific article published on September 1997

Role of MMP-9 and its tissue inhibitor TIMP-1 in human osteosarcoma: findings in 42 patients followed for 1-16 years

scientific article published on 01 August 2004

Sacral Chordoma: Long-term Outcome of a Large Series of Patients Surgically Treated at Two Reference Centers.

scientific article

Sacral osteoid osteoma and osteoblastoma: a report of 13 cases

scientific article published on 01 January 1986

Sclerosing epithelioid fibrosarcoma of the thigh: report of two cases with synchronous bone metastases.

scientific article

Screening for potential targets for therapy in mesenchymal, clear cell, and dedifferentiated chondrosarcoma reveals Bcl-2 family members and TGFβ as potential targets.

scientific article

Second malignancy in 597 patients with ewing sarcoma of bone treated at a single institution with adjuvant and neoadjuvant chemotherapy between 1972 and 1999

scientific article published on 01 October 2005

Second malignant neoplasm in patients with osteosarcoma of the extremities treated with adjuvant and neoadjuvant chemotherapy

scientific article published in December 2006

Sequencing IDH1/2 glioma mutation hotspots in gliomas and malignant peripheral nerve sheath tumors

scientific article published on 4 December 2013

Short, Full-Dose Adjuvant Chemotherapy in High-Risk Adult Soft Tissue Sarcomas: A Randomized Clinical Trial From the Italian Sarcoma Group and the Spanish Sarcoma Group

article

Short, full-dose adjuvant chemotherapy (CT) in high-risk adult soft tissue sarcomas (STS): long-term follow-up of a randomized clinical trial from the Italian Sarcoma Group and the Spanish Sarcoma Group

scientific article published on 11 October 2016

Significant association between human osteosarcoma and simian virus 40.

scientific article

Simultaneous paired analysis of numerical chromosomal aberrations and DNA content in osteosarcoma.

scientific article published in July 2001

Small cell osteosarcoma: clinicopathologic, immunohistochemical, and molecular analysis of 36 cases.

scientific article published in May 2015

Soft Tissue Tumors Rarely Presenting Primary in Bone; Diagnostic Pitfalls.

scientific article published on 29 June 2017

Solid variant of aneurysmal bone cyst

scientific article published on 01 February 1993

Sorafenib and everolimus for patients with unresectable high-grade osteosarcoma progressing after standard treatment: a non-randomised phase 2 clinical trial.

scientific article

Sorafenib blocks tumour growth, angiogenesis and metastatic potential in preclinical models of osteosarcoma through a mechanism potentially involving the inhibition of ERK1/2, MCL-1 and ezrin pathways

scientific article

Suppression of deacetylase SIRT1 mediates tumor-suppressive NOTCH response and offers a novel treatment option in metastatic Ewing sarcoma

scientific article published on 3 October 2014

Surgical treatment and results of 62 patients with epithelioid hemangioendothelioma of bone

scientific article published on 18 March 2014

Survival in high-grade osteosarcoma: improvement over 21 years at a single institution

scientific article published on 04 November 2009

Survival meta-analyses for >1800 malignant peripheral nerve sheath tumor patients with and without neurofibromatosis type 1.

scientific article published on 15 November 2012

Synovial sarcoma: retrospective analysis of 250 patients treated at a single institution.

scientific article

Targeted therapies in bone sarcomas.

scientific article

Targeting CD99 in association with doxorubicin: an effective combined treatment for Ewing's sarcoma

scientific article published on 2 December 2005

Targeting GSTP1-1 induces JNK activation and leads to apoptosis in cisplatin-sensitive and -resistant human osteosarcoma cell lines.

scientific article published on 9 November 2011

Targeting glutathione-S transferase enzymes in musculoskeletal sarcomas: a promising therapeutic strategy.

scientific article published in January 2011

Targeting insulin-like growth factor 1 receptor in sarcomas

scientific article published on July 2008

Targeting polo-like kinase 1 by NMS-P937 in osteosarcoma cell lines inhibits tumor cell growth and partially overcomes drug resistance

scientific article published on 7 September 2014

Tenosynovial giant cell tumour/pigmented villonodular synovitis: outcome of 294 patients before the era of kinase inhibitors.

scientific article published on 24 November 2014

The Combination of Sorafenib and Everolimus Abrogates mTORC1 and mTORC2 upregulation in osteosarcoma preclinical models.

scientific article published on 22 February 2013

The Istituto Rizzoli experience with small cell osteosarcoma.

scientific article published on December 1989

The expression of P-glycoprotein is causally related to a less aggressive phenotype in human osteosarcoma cells.

scientific article

The expression of ccn3(nov) gene in musculoskeletal tumors

scientific article published on March 2002

The genomic landscape of the Ewing Sarcoma family of tumors reveals recurrent STAG2 mutation

scientific article

The incidental skeletal lesion: ignore or explore?

scientific article published on 02 October 2009

The role of FDG PET/CT in patients treated with neoadjuvant chemotherapy for localized bone sarcomas

scientific article published on 20 September 2016

The role of surgical margins in treatment of Ewing's sarcoma family tumors: experience of a single institution with 512 patients treated with adjuvant and neoadjuvant chemotherapy

scientific article published on 19 April 2006

The t(X;6) in subungual exostosis results in transcriptional deregulation of the gene for insulin receptor substrate 4

scientific article published on 01 January 2011

The treatment of localized Ewing's sarcoma: the experience at the Istituto Ortopedico Rizzoli in 163 cases treated with and without adjuvant chemotherapy

scientific article published on 01 April 1982

The treatment of nonmetastatic high grade osteosarcoma of the extremity: review of the Italian Rizzoli experience. Impact on the future.

scientific article published on January 2009

Trabectedin efficacy in Ewing sarcoma is greatly increased by combination with anti-IGF signaling agents.

scientific article

Treatment and outcome of recurrent osteosarcoma: experience at Rizzoli in 235 patients initially treated with neoadjuvant chemotherapy

scientific article published on 01 January 2005

Treatment and prognosis for synchronous multifocal osteosarcoma in 42 patients

Troglitazione affects survival of human osteosarcoma cells

scientific article published in March 2002

Tumor response assessment by modified Choi criteria in localized high-risk soft tissue sarcoma treated with chemotherapy

scientific article published on 17 May 2012

Tumoral immune-infiltrate (IF), PD-L1 expression and role of CD8/TIA-1 lymphocytes in localized osteosarcoma patients treated within protocol ISG-OS1.

scientific article published on 4 December 2017

Tumours of the patella

scientific article published on 01 January 1991

Unlocking bone for proteomic analysis and FISH

scientific article published on 18 January 2019

Value of P-glycoprotein and clinicopathologic factors as the basis for new treatment strategies in high-grade osteosarcoma of the extremities

scientific article

Vascular bone tumors: a proposal of a classification based on clinicopathological, radiographic and genetic features ⬇️

scientific article published on September 21, 2012

miR-196a expression in human and canine osteosarcomas: a comparative study

scientific article

miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancy

scientific article published on April 2012

miRNA expression profile in human osteosarcoma: role of miR-1 and miR-133b in proliferation and cell cycle control.

scientific article published on 28 November 2012

p16 expression as a prognostic and predictive marker in high-grade localized osteosarcoma of the extremities: an analysis of 357 cases.

scientific article published on 17 August 2016

p53-dependent activation of microRNA-34a in response to etoposide-induced DNA damage in osteosarcoma cell lines not impaired by dominant negative p53 expression

scientific article published on 9 December 2014

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