Search filters

List of works by Mar Cuadrado-Tejedor

A First-in-Class Small-Molecule that Acts as a Dual Inhibitor of HDAC and PDE5 and that Rescues Hippocampal Synaptic Impairment in Alzheimer's Disease Mice.

scientific article published on 23 August 2016

Abnormal alpha-synuclein interactions with Rab proteins in alpha-synuclein A30P transgenic mice.

scientific article published in April 2004

Advanced Assay Monitoring APP-Carboxyl-Terminal Fragments as Markers of APP Processing in Alzheimer Disease Mouse Models

scientific article published on 01 January 2016

Age-related mitochondrial alterations without neuronal loss in the hippocampus of a transgenic model of Alzheimer's disease.

scientific article

Changes in cytoskeletal gene expression linked to MPTP-treatment in Mice

scientific article published on 6 July 2005

Chronic Mild Stress Assay Leading to Early Onset and Propagation of Alzheimer's Disease Phenotype in Mouse Models

scientific article published in January 2016

Chronic mild stress accelerates the onset and progression of the Alzheimer's disease phenotype in Tg2576 mice

scientific article published in January 2012

Chronic mild stress in mice promotes cognitive impairment and CDK5-dependent tau hyperphosphorylation.

scientific article published on 14 January 2011

Concomitant histone deacetylase and phosphodiesterase 5 inhibition synergistically prevents the disruption in synaptic plasticity and it reverses cognitive impairment in a mouse model of Alzheimer's disease

scientific article

Current animal models of Alzheimer's disease: challenges in translational research

scientific article published on 29 September 2014

Decreased levels of guanosine 3', 5'-monophosphate (cGMP) in cerebrospinal fluid (CSF) are associated with cognitive decline and amyloid pathology in Alzheimer's disease

scientific article published in June 2015

Design, Synthesis, and Biological Evaluation of First-in-Class Dual Acting Histone Deacetylases (HDACs) and Phosphodiesterase 5 (PDE5) Inhibitors for the Treatment of Alzheimer's Disease.

scientific article published on 8 September 2016

Discovery of in Vivo Chemical Probes for Treating Alzheimer's Disease: Dual Phosphodiesterase 5 (PDE5) and Class I Histone Deacetylase Selective Inhibitors

scientific article published on 21 December 2018

Early changes in hippocampal Eph receptors precede the onset of memory decline in mouse models of Alzheimer's disease.

scientific article published in January 2009

Enhanced expression of the voltage-dependent anion channel 1 (VDAC1) in Alzheimer's disease transgenic mice: an insight into the pathogenic effects of amyloid-β.

scientific article published on January 2011

Epigenetic drugs in Alzheimer's disease

scientific article

GLUT12 Expression in Brain of Mouse Models of Alzheimer's Disease

scientific article published on 31 August 2019

Impact of Scaffold Exploration on Novel Dual-Acting Histone Deacetylases and Phosphodiesterase 5 Inhibitors for the Treatment of Alzheimer's Disease

scientific article

Insulin-like growth factor 2 reverses memory and synaptic deficits in APP transgenic mice

scientific article

La proteína priónica celular en el sistema nervioso central de mamíferos. Correlatos anatomoclínicos

scientific article published on 01 May 2010

Long-term phenylbutyrate administration prevents memory deficits in Tg2576 mice by decreasing Abeta

scientific article published in June 2011

Multitarget Approach for the Treatment of Alzheimer's Disease: Inhibition of Phosphodiesterase 9 (PDE9) and Histone Deacetylases (HDACs) Covering Diverse Selectivity Profiles

scientific article published on 04 September 2019

Overexpression of wild-type human APP in mice causes cognitive deficits and pathological features unrelated to Abeta levels.

scientific article

Pharmacokinetic investigation of sildenafil using positron emission tomography and determination of its effect on cerebrospinal fluid cGMP levels

scientific article published on 7 December 2015

Phenylbutyrate ameliorates cognitive deficit and reduces tau pathology in an Alzheimer's disease mouse model

scientific article published on 14 January 2009

Phenylbutyrate is a multifaceted drug that exerts neuroprotective effects and reverses the Alzheimer´s disease-like phenotype of a commonly used mouse model

scientific article

Phenylbutyrate rescues dendritic spine loss associated with memory deficits in a mouse model of Alzheimer disease

scientific article published on 10 November 2010

Phosphodiesterase inhibition in cognitive decline

scientific article

Rosiglitazone rescues memory impairment in Alzheimer's transgenic mice: mechanisms involving a reduced amyloid and tau pathology

scientific article published on 24 March 2010

Sildenafil protects against 3-nitropropionic acid neurotoxicity through the modulation of calpain, CREB, and BDNF.

scientific article published on 25 January 2010

Sildenafil restores cognitive function without affecting β-amyloid burden in a mouse model of Alzheimer's disease.

scientific article published on December 2011

Synthesis and evaluation of (13)N-labelled azo compounds for β-amyloid imaging in mice

scientific article published on 6 December 2013

Tadalafil crosses the blood-brain barrier and reverses cognitive dysfunction in a mouse model of AD.

scientific article

The cellular prion protein and its role in Alzheimer disease

scientific article published on 29 April 2009

Paulina is supported by:

About Paulina

Help