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List of works by Massimo Conese

A VSV-G Pseudotyped Last Generation Lentiviral Vector Mediates High Level and Persistent Gene Transfer in Models of Airway Epithelium In Vitro and In Vivo ⬇️

scientific article published on August 2, 2010

A Vaccine against Cancer: Can There Be a Possible Strategy to Face the Challenge? Possible Targets and Paradoxical Effects

scientific article published in 2023

A ligand-free, soluble urokinase receptor is present in the ascitic fluid from patients with ovarian cancer.

scientific article

Airway epithelial cell-pathogen interactions

scientific article published in August 2004

Amniotic mesenchymal stem cells: a new source for hepatocyte-like cells and induction of CFTR expression by coculture with cystic fibrosis airway epithelial cells

scientific article

Analysis of inflammatory and immune response biomarkers in sputum and exhaled breath condensate by a multi-parametric biochip array in cystic fibrosis

scientific article published on 01 April 2011

Antibiotic therapy affects functional behaviour in cystic fibrosis blood mononuclear cells.

scientific article published on 11 June 2015

Assembly and Functional Analysis of an S/MAR Based Episome with the Cystic Fibrosis Transmembrane Conductance Regulator Gene

scientific article published on 17 April 2018

Bacterial infections and inflammation in the lungs of cystic fibrosis patients

scientific article

Bacterial internalization is not sufficient to clear Pseudomonas aeruginosa infection in human fetal airway xenografts

scientific article published on 01 December 2010

Biodistribution and transgene expression with nonviral cationic vector/DNA complexes in the lungs

scientific article published in October 2000

Biological cost of hypermutation in Pseudomonas aeruginosa strains from patients with cystic fibrosis

scientific article published on 01 May 2007

Blood and tissue fibrinolytic profiles in patients with colorectal carcinoma.

scientific article

Burkholderia cenocepacia strains isolated from cystic fibrosis patients are apparently more invasive and more virulent than rhizosphere strains

scientific article

CFTR expression and activity from the human CFTR locus in BAC vectors, with regulatory regions, isolated by a single-step procedure

scientific article published on 10 June 2010

CFTR-dependent chloride efflux in cystic fibrosis mononuclear cells is increased by ivacaftor therapy

scientific article published on 26 April 2017

Comparison between cationic polymers and lipids in mediating systemic gene delivery to the lungs

scientific article

Correction of defective CFTR/ENaC function and tightness of cystic fibrosis airway epithelium by amniotic mesenchymal stromal (stem) cells

scientific article

Correctors of mutant CFTR enhance subcortical cAMP-PKA signaling through modulating ezrin phosphorylation and cytoskeleton organization.

scientific article

Cultured human mesangial cells produce both type 1 and type 2 plasminogen activator inhibitors

scientific article published on 01 December 1995

Cystic Fibrosis and the Innate Immune System: Therapeutic Implications ⬇️

scientific article published on March 1, 2011

Cytokine levels in sputum of cystic fibrosis patients before and after antibiotic therapy

scientific article

Dysregulated interleukin-8 secretion and NF-kappaB activity in human cystic fibrosis nasal epithelial cells

scientific article

Effect of acute lung injury on VLA-4 and CXCR4 expression in resident and circulating hematopoietic stem/progenitor cells

scientific article

Effects of treatment in the levels of circulating cytokines and growth factors in cystic fibrosis and dialyzed patients by multi-analytical determination with a biochip array platform

scientific article published on 19 April 2013

Engraftment of bone marrow-derived stem cells to the lung in a model of acute respiratory infection by Pseudomonas aeruginosa.

scientific article

Evaluation of genome-wide expression profiles of blood and sputum neutrophils in cystic fibrosis patients before and after antibiotic therapy

scientific article

Functional human CFTR produced by a stable minichromosome

scientific article published on 16 August 2002

G-CSF and GM-CSF Modify Neutrophil Functions at Concentrations found in Cystic Fibrosis

scientific article published on 10 September 2019

Gap Junctions Are Involved in the Rescue of CFTR-Dependent Chloride Efflux by Amniotic Mesenchymal Stem Cells in Coculture with Cystic Fibrosis CFBE41o- Cells

scientific article published on 11 January 2018

Gene and cell therapy for cystic fibrosis: From bench to bedside ⬇️

scientific article published on June 1, 2011

Gene therapy progress and prospects: episomally maintained self-replicating systems.

scientific article published in December 2004

Gene transfer by means of lipo- and polyplexes: role of clathrin and caveolae-mediated endocytosis

scientific article published on January 2006

Genomic context vectors and artificial chromosomes for cystic fibrosis gene therapy.

scientific article published on June 2007

Hematopoietic and mesenchymal stem cells for the treatment of chronic respiratory diseases: role of plasticity and heterogeneity

scientific article

Hematopoietic stem/progenitor cells express functional mitochondrial energy-dependent cystic fibrosis transmembrane conductance regulator

scientific article published on 20 June 2011

Human Amniotic Mesenchymal Stem Cells and Fibroblasts Accelerate Wound Repair of Cystic Fibrosis Epithelium

scientific article published on 19 May 2022

Human Cellular Models for the Investigation of Lung Inflammation and Mucus Production in Cystic Fibrosis

scientific article published on 15 November 2018

Human airway epithelial cells investigated by atomic force microscopy: A hint to cystic fibrosis epithelial pathology.

scientific article published on 30 August 2016

Human amnion-derived cells: prospects for the treatment of lung diseases.

scientific article published on January 2014

Human respiratory cells from nasal polyps as a model for gene transfer by non-viral cationic vectors

scientific article published on 01 January 2001

Impact of chronic pulmonary infection with Pseudomonas aeruginosa on transfection mediated by viral and nonviral vectors

scientific article published in March 2010

Impact of lentiviral vector-mediated transduction on the tightness of a polarized model of airway epithelium and effect of cationic polymer polyethylenimine

scientific article published on 21 June 2010

Increase in interleukin-8 production from circulating neutrophils upon antibiotic therapy in cystic fibrosis patients

scientific article

Inhibition of nonviral cationic liposome-mediated gene transfer into primary human respiratory cells by interferon-gamma

scientific article published on 18 June 2002

Inhibitory effect of retinoids on the generation of procoagulant activity by blood mononuclear phagocytes

scientific article published on 01 December 1991

Insulin-Like Growth Factor Binding Protein 6 Is Secreted in Extracellular Vesicles upon Hyperthermia and Oxidative Stress in Dendritic Cells But Not in Monocytes

scientific article published on 22 June 2020

Insulin-like growth factor-6 (IGFBP-6) stimulates neutrophil oxidative burst, degranulation and chemotaxis.

scientific article published on 30 October 2017

Intranasal delivery of dopamine to the striatum using glycol chitosan/sulfobutylether-β-cyclodextrin based nanoparticles.

scientific article

Involvement of glycosaminoglycans in vesicular stomatitis virus G glycoprotein pseudotyped lentiviral vector-mediated gene transfer into airway epithelial cells.

scientific article published on December 2008

Isolation and characterization of microparticles in sputum from cystic fibrosis patients

scientific article

Late generation lentiviral vectors: evaluation of inflammatory potential in human airway epithelial cells.

scientific article

Lentiviral Vectors and Cystic Fibrosis Gene Therapy ⬇️

scientific article published on January 29, 2010

Lentiviral small hairpin RNA delivery reduces apical sodium channel activity in differentiated human airway epithelial cells ⬇️

scientific article published on December 1, 2012

Lentivirus-mediated gene transfer to the respiratory epithelium: a promising approach to gene therapy of cystic fibrosis.

scientific article published in October 2004

Magnetically guided lentiviral-mediated transduction of airway epithelial cells

scientific article published on September 2010

Metabolic correction in oligodendrocytes derived from metachromatic leukodystrophy mouse model by using encapsulated recombinant myoblasts

scientific article

Modification of transepithelial ion transport in human cultured bronchial epithelial cells by interferon-gamma

scientific article published on 01 June 2000

Molecular links between endocrine, nervous and immune system during chronic stress

scientific article published on 08 December 2020

Mucoadhesive Properties and Interaction with P-Glycoprotein (P-gp) of Thiolated-Chitosans and -Glycol Chitosans and Corresponding Parent Polymers: A Comparative Study

scientific article published on 24 February 2014

NHERF1 and CFTR restore tight junction organisation and function in cystic fibrosis airway epithelial cells: role of ezrin and the RhoA/ROCK pathway.

scientific article published on 10 September 2012

Na+/H+ exchanger regulatory factor 1 overexpression-dependent increase of cytoskeleton organization is fundamental in the rescue of F508del cystic fibrosis transmembrane conductance regulator in human airway CFBE41o- cells

scientific article

Na+/H+ exchanger regulatory factor isoform 1 overexpression modulates cystic fibrosis transmembrane conductance regulator (CFTR) expression and activity in human airway 16HBE14o- cells and rescues DeltaF508 CFTR functional expression in cystic fibro

scientific article published on 3 October 2005

Nanocarriers for respiratory diseases treatment: recent advances and current challenges

scientific article published on January 2014

Nanoparticle delivery of grape seed-derived proanthocyanidins to airway epithelial cells dampens oxidative stress and inflammation.

scientific article

National scientific associations should have a key role in adapting and implementing standard of care guidelines in European countries

scientific article published on 25 October 2005

Neovascularization is a key feature of liver fibrosis progression: anti-angiogenesis as an innovative way of liver fibrosis treatment

scientific article published on 10 February 2020

Neutrophil recruitment and airway epithelial cell involvement in chronic cystic fibrosis lung disease.

scientific article published in September 2003

Non-viral approach toward gene therapy of cystic fibrosis lung disease.

scientific article

Nonmucoid Pseudomonas aeruginosa expresses alginate in the lungs of patients with cystic fibrosis and in a mouse model.

scientific article

Not All Is CFTR - Neutrophils and Cholesterol in Cystic Fibrosis.

scientific article

Oral Manifestations in HIV-Positive Children: A Systematic Review

scientific article published on 31 January 2020

PAI-1 inhibits urokinase-induced chemotaxis by internalizing the urokinase receptor

scientific article published on 01 September 2001

PMA-induced down-regulation of the receptor for alpha 2-macroglobulin in human U937 cells.

scientific article published on January 1995

Paracrine effects and heterogeneity of marrow-derived stem/progenitor cells: relevance for the treatment of respiratory diseases.

scientific article published on 04 May 2013

Pilot Randomized Controlled Trial Evaluating the Effect of Hypertonic Saline With and Without Hyaluronic Acid in Reducing Inflammation in Cystic Fibrosis.

scientific article published on 5 May 2016

Polyethylenimine-mediated gene delivery to the lung and therapeutic applications.

scientific article published on 6 February 2009

Pro-inflammatory effect of cystic fibrosis sputum microparticles in the murine lung

scientific article published on 06 April 2013

Procoagulant activity of mononuclear phagocytes from different anatomical sites in patients with gynecological malignancies

scientific article published on February 1990

Protease nexin-1-urokinase complexes are internalized and degraded through a mechanism that requires both urokinase receptor and alpha 2-macroglobulin receptor.

scientific article published on July 1994

Pseudomonas aeruginosa infection destroys the barrier function of lung epithelium and enhances polyplex-mediated transfection

scientific article published in July 2007

Recycling of the urokinase receptor upon internalization of the uPA:serpin complexes

scientific article

Reduction of tumor-associated fibrinolytic-activity by antimetastatic dosages of 2 ru(ii)-dmso complexes in mice bearing lewis lung-carcinoma

scientific article published on 01 April 1993

Removal of domain D2 or D3 of the human urokinase receptor does not affect ligand affinity

scientific article published on February 1996

Restoration of bacterial killing activity of human respiratory cystic fibrosis cells through cationic vector-mediated cystic fibrosis transmembrane conductance regulator gene transfer

scientific article published in August 1999

Retinoic acid stimulates plasminogen activator inhibitor 2 production by blood mononuclear cells and inhibits urokinase-induced extracellular proteolysis

scientific article published on 01 November 1999

Retinoids inhibit the respiratory burst and degranulation of stimulated human polymorphonuclear leukocytes

scientific article published on 01 November 1991

Role of Biophysical Parameters on ex Vivo and in Vivo Gene Transfer to the Airway Epithelium by Polyethylenimine/Albumin Complexes

article

Role of clathrin- and caveolae-mediated endocytosis in gene transfer mediated by lipo- and polyplexes

scientific article published on September 2005

S-CMC-Lys protective effects on human respiratory cells during oxidative stress

scientific article

S-CMC-Lys-dependent stimulation of electrogenic glutathione secretion by human respiratory epithelium.

scientific article published on 11 November 2005

Serum albumin enhances polyethylenimine-mediated gene delivery to human respiratory epithelial cells

scientific article published on December 2005

Stem cells and cystic fibrosis.

scientific article

Stimulation of β2-adrenergic receptor increases CFTR function and decreases ATP levels in murine hematopoietic stem/progenitor cells

scientific article published on 29 August 2014

Synthesis and characterization of novel chitosan-dopamine or chitosan-tyrosine conjugates for potential nose-to-brain delivery

scientific article published on 30 August 2020

Systemic heparin delivery by the pulmonary route using chitosan and glycol chitosan nanoparticles.

scientific article published on 20 February 2013

The Fountain of Youth: A Tale of Parabiosis, Stem Cells, and Rejuvenation

scientific article published on 28 October 2017

The Role of Adipose-Derived Stem Cells, Dermal Regenerative Templates, and Platelet-Rich Plasma in Tissue Engineering-Based Treatments of Chronic Skin Wounds

scientific article published on 09 January 2020

The novel complex allele [A238V;F508del] of the CFTR gene: clinical phenotype and possible implications for cystic fibrosis etiological therapies

scientific article

The urokinase/urokinase-receptor system and cancer invasion

scientific article published on June 1995

Treatment of Cystic Fibrosis Patients Homozygous for F508del with Lumacaftor-Ivacaftor (Orkambi®) Restores Defective CFTR Channel Function in Circulating Mononuclear Cells

scientific article published on 31 March 2020

Tumor necrosis factor-alpha in airway secretions from cystic fibrosis patients upregulate endothelial adhesion molecules and induce airway epithelial cell apoptosis: implications for cystic fibrosis lung disease

scientific article published on 01 October 2008

Urokinase/urokinase receptor system: internalization/degradation of urokinase-serpin complexes: mechanism and regulation.

scientific article published in March 1995

Validation of an automated sensitive immunoassay for quantitation of cytokines in the sputum of cystic fibrosis patients

scientific article published on 01 January 2007

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