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List of works by Jose A Martinez-Climent

A cyclin-D1 interaction with BAX underlies its oncogenic role and potential as a therapeutic target in mantle cell lymphoma

scientific article

A quantitative analysis of genomic instability in lymphoid and plasma cell neoplasms based on the PIG-A gene.

scientific article

Abnormalities of chromosome band 11q23 and the MLL gene in pediatric myelomonocytic and monoblastic leukemias. Identification of the t(9;11) as an indicator of long survival

scientific article published on 01 November 1995

Abnormalities on 1q and 7q are associated with poor outcome in sporadic Burkitt's lymphoma. A cytogenetic and comparative genomic hybridization study

scientific article published on 01 October 2003

Acquired mutations in BCL2 family proteins conferring resistance to the BH3 mimetic ABT-199 in lymphoma.

scientific article published on 30 April 2014

Acute lymphoblastic leukaemia in a child with hereditary spherocytosis

scientific article published on 01 September 1995

Additional cytogenetic changes do not influence the outcome of patients with newly diagnosed acute promyelocytic leukemia treated with an ATRA plus anthracyclin based protocol. A report of the Spanish group PETHEMA

scientific article published on 01 August 2001

Analysis of translocations that involve the NUP98 gene in patients with 11p15 chromosomal rearrangements

scientific article published in December 2004

BCR-ABL induces the expression of Skp2 through the PI3K pathway to promote p27Kip1 degradation and proliferation of chronic myelogenous leukemia cells

scientific article published on 01 April 2005

Bcl-6 mutation status provides clinically valuable information in early-stage B-cell chronic lymphocytic leukemia.

scientific article published in April 2004

Biallelic inactivation of TRAF3 in a subset of B-cell lymphomas with interstitial del(14)(q24.1q32.33).

scientific article

Blockade of the NFκB pathway drives differentiating glioblastoma-initiating cells into senescence both in vitro and in vivo.

scientific article

C/EBPα induces highly efficient macrophage transdifferentiation of B lymphoma and leukemia cell lines and impairs their tumorigenicity

scientific article

Cellular plasticity confers migratory and invasive advantages to a population of glioblastoma-initiating cells that infiltrate peritumoral tissue.

scientific article published on June 2013

Characterization of 8p21.3 chromosomal deletions in B-cell lymphoma: TRAIL-R1 and TRAIL-R2 as candidate dosage-dependent tumor suppressor genes.

scientific article

Chromosomal abnormalities in women with breast cancer after autologous stem cell transplantation are infrequent and may not predict development of therapy-related leukemia or myelodysplastic syndrome

scientific article published on 01 June 2000

Clinical and prognostic significance of chromosomal abnormalities in childhood acute myeloid leukemia de novo

scientific article published on 01 January 1995

Combined clinical and genomic signatures for the prognosis of early stage non-small cell lung cancer based on gene copy number alterations

scientific article

Comprehensive whole genome array CGH profiling of mantle cell lymphoma model genomes.

scientific article published on 30 June 2004

Cytogenetic response induced by interferon alpha in the myeloproliferative disorder with eosinophilia, T cell lymphoma and the chromosomal translocation t(8;13)(p11;q12)

scientific article published in June 1998

DNA methylation profiling identifies two splenic marginal zone lymphoma subgroups with different clinical and genetic features

scientific article published on 22 January 2015

Deletion of chromosome 11q predicts response to anthracycline-based chemotherapy in early breast cancer

scientific article published on 01 January 2007

Deregulation of the telomerase reverse transcriptase (TERT) gene by chromosomal translocations in B-cell malignancies

scientific article published on 11 May 2010

Detection of 11q23/MLL rearrangements in infant leukemias with fluorescence in situ hybridization and molecular analysis.

scientific article published on August 1995

Detection of translocations affecting the BCL6 locus in B cell non-Hodgkin's lymphoma by interphase fluorescence in situ hybridization

scientific article published on 01 September 2001

Divergence of Vascular Specification in Visceral Lymphoid Organs-Genetic Determinants and Differentiation Checkpoints.

scientific article published on 17 July 2015

Do long lived seabirds reduce the negative effects of acute pollution on adult survival by skipping breeding? A study with European storm petrels (Hydrobates pelagicus) during the "Prestige" oil-spill

scientific article published on 29 September 2010

Downregulation of FOXP1 is required during germinal center B-cell function.

scientific article published on 11 April 2013

Epigenetic down-regulation of BIM expression is associated with reduced optimal responses to imatinib treatment in chronic myeloid leukaemia.

scientific article published on 4 May 2009

Epigenetic regulation of miRNA genes in acute leukemia.

scientific article published on 06 December 2011

Expression of MALT1 oncogene in hematopoietic stem/progenitor cells recapitulates the pathogenesis of human lymphoma in mice ⬇️

scientific article published on June 11, 2012

Expression profiles of adult T-cell leukemia-lymphoma and associations with clinical responses to zidovudine and interferon alpha

scientific article

GeneChip analyses point to novel pathogenetic mechanisms in mantle cell lymphoma

scientific article

Genomic abnormalities acquired in the blastic transformation of splenic marginal zone B-cell lymphoma.

scientific article published on March 2003

Genomic loss of 18p predicts an adverse clinical outcome in patients with high-risk breast cancer

scientific article published in December 2002

Genomic profiling of mantle cell lymphoma

scientific article

High-throughput sequencing analysis of the chromosome 7q32 deletion reveals IRF5 as a potential tumour suppressor in splenic marginal-zone lymphoma.

scientific article

Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics

scientific article

Homozygous deletion of SOCS1 in primary mediastinal B-cell lymphoma detected by CGH to BAC microarrays

scientific article published on 01 June 2005

Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas

scientific article published on 7 September 2006

Identification and molecular characterization of CALM/AF10fusion products in T cell acute lymphoblastic leukemia and acute myeloid leukemia

scientific article

Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma ⬇️

scientific article published on April 19, 2012

Identification of two subgroups of mantle cell leukemia with distinct clinical and biological features

scientific article published on 01 January 2001

Identified hidden genomic changes in mantle cell lymphoma using high-resolution single nucleotide polymorphism genomic array

scientific article published on 27 May 2009

Imatinib mesylate (STI571) treatment in patients with chronic-phase chronic myelogenous leukaemia previously submitted to autologous stem cell transplantation.

scientific article

Integrative oncogenomic analysis of microarray data in hematologic malignancies

scientific article

Interphase FISH assays for the detection of translocations with breakpoints in immunoglobulin light chain loci

scientific article published on 01 March 2002

Intrinsic resistance to PIM kinase inhibition in AML through p38α-mediated feedback activation of mTOR signaling

scientific article published on 05 June 2016

Involvement of miRNAs in the differentiation of human glioblastoma multiforme stem-like cells

scientific article

KLF2 mutation is the most frequent somatic change in splenic marginal zone lymphoma and identifies a subset with distinct genotype

scientific article published on 27 November 2014

LITAF, a BCL6 target gene, regulates autophagy in mature B-cell lymphomas.

scientific article

LMO2 expression reflects the different stages of blast maturation and genetic features in B-cell acute lymphoblastic leukemia and predicts clinical outcome.

scientific article

Lineage-specific function of Engrailed-2 in the progression of chronic myelogenous leukemia to T-cell blast crisis.

scientific article published on 25 March 2014

Loss of a novel tumor suppressor gene locus at chromosome 8p is associated with leukemic mantle cell lymphoma

scientific article published on 01 December 2001

MALT lymphoma meets stem cells

scientific article published on 24 July 2012

MALT1 is deregulated by both chromosomal translocation and amplification in B-cell non-Hodgkin lymphoma.

scientific article

MALT1 small molecule inhibitors specifically suppress ABC-DLBCL in vitro and in vivo

scientific article published on December 2012

Mantle-cell lymphoma genotypes identified with CGH to BAC microarrays define a leukemic subgroup of disease and predict patient outcome

scientific article

Molecular analysis of the Mono Mac 6 cell line: detection of an MLL-AF9 fusion transcript

scientific article published on 01 February 1995

Molecular cytogenetics of childhood hematological malignancies ⬇️

scientific article published on December 1, 1997

Molecular heterogeneity in MCL defined by the use of specific VH genes and the frequency of somatic mutations.

scientific article published on 2 January 2003

Non-malignant tumors that can mimic cancer during the neonatal period

scientific article published on 01 June 1995

Novel genomic imbalances in B-cell splenic marginal zone lymphomas revealed by comparative genomic hybridization and cytogenetics.

scientific article published in May 2001

ODZ1 allows glioblastoma to sustain invasiveness through a Myc-dependent transcriptional upregulation of RhoA.

scientific article published on 19 September 2016

PD-1/PD-L1 immune checkpoint and p53 loss facilitate tumor progression in activated B-cell diffuse large B-cell lymphomas

scientific article published on 11 April 2019

PIM2 inhibition as a rational therapeutic approach in B-cell lymphoma

scientific article published on 21 September 2011

Partial uniparental disomy: a recurrent genetic mechanism alternative to chromosomal deletion in malignant lymphoma

scientific article published on 01 May 2006

Pediatricians and cancer prevention

scientific article published on 01 February 1997

Preclinical activity of LBH589 alone or in combination with chemotherapy in a xenogeneic mouse model of human acute lymphoblastic leukemia.

scientific article

Recurrent loss of the Y chromosome and homozygous deletions within the pseudoautosomal region 1: association with male predominance in mantle cell lymphoma

scientific article published on 01 June 2008

Reversion of epigenetically mediated BIM silencing overcomes chemoresistance in Burkitt lymphoma.

scientific article published on 22 June 2010

Richter transformation driven by Epstein-Barr virus reactivation during therapy-related immunosuppression in chronic lymphocytic leukemia

scientific article published on 21 February 2018

Scale for assessing quality of life of children survivors of cranial posterior fossa tumors.

scientific article published in January 1994

Soluble intercellular adhesion molecule-1 (s-ICAM-1/s-CD54) in diffuse large B-cell lymphoma: association with clinical characteristics and outcome

scientific article published in March 2003

The BCL6 gene in B-cell lymphomas with 3q27 translocations is expressed mainly from the rearranged allele irrespective of the partner gene

scientific article published on 01 July 2003

The molecular signature of mantle cell lymphoma reveals multiple signals favoring cell survival.

scientific article published in December 2003

The origin and targeting of mucosa-associated lymphoid tissue lymphomas

scientific article published on July 2014

Transformation of follicular lymphoma to diffuse large cell lymphoma is associated with a heterogeneous set of DNA copy number and gene expression alterations

scientific article published on 24 October 2002

Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma

scientific article

Variant three-way translocation of inversion 16 in AML-M4Eo confirmed by fluorescence in situ hybridization analysis.

scientific article

[Acute megakaryoblastic leukemia in infancy]

scientific article published on 01 June 1993

[Applications of fluorescence in situ hybridization (FISH) in acute lymphoblastic leukemia]

scientific article published on 01 August 1999

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