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List of works by Michiel Kleerebezem

10 years of the nisin-controlled gene expression system (NICE) in Lactococcus lactis

scientific article

A comprehensive metatranscriptome analysis pipeline and its validation using human small intestine microbiota datasets

scientific article

An in silico analysis of T-box regulated genes and T-box evolution in prokaryotes, with emphasis on prediction of substrate specificity of transporters

scientific article

An intimate tête-à-tête — How probiotic lactobacilli communicate with the host ⬇️

scientific article published on July 27, 2011

Butyrate-producing Clostridium cluster XIVa species specifically colonize mucins in an in vitro gut model

scientific article published on 13 December 2012

Can probiotics modulate human disease by impacting intestinal barrier function?

scientific article (publication date: 2017)

Cell surface-associated compounds of probiotic lactobacilli sustain the strain-specificity dogma ⬇️

scientific article published on June 28, 2013

Cell to cell communication by autoinducing peptides in gram-positive bacteria

scientific article

Characterization and functional analysis of the poxB gene, which encodes pyruvate oxidase in Lactobacillus plantarum

scientific article

Comparative genomics analysis of Streptococcus isolates from the human small intestine reveals their adaptation to a highly dynamic ecosystem

scientific article

Comparison of the effects of five dietary fibers on mucosal transcriptional profiles, and luminal microbiota composition and SCFA concentrations in murine colon.

scientific article published on 17 June 2015

Competitive selection of lactic acid bacteria that persist in the human oral cavity

scientific article

Complete Genome Sequence of Streptococcus salivarius HSISS4, a Human Commensal Bacterium Highly Prevalent in the Digestive Tract

scientific article

Complete genome sequence of Lactobacillus plantarum WCFS1

scientific article

Complete sequences of four plasmids of Lactococcus lactis subsp. cremoris SK11 reveal extensive adaptation to the dairy environment

scientific article

Congruent strain specific intestinal persistence of Lactobacillus plantarum in an intestine-mimicking in vitro system and in human volunteers

scientific article

Dietary calcium phosphate strongly impacts gut microbiome changes elicited by inulin and galacto-oligosaccharides consumption

scientific article published on 04 November 2021

Dietary heme alters microbiota and mucosa of mouse colon without functional changes in host-microbe cross-talk

scientific article

Differential NF-kappaB pathways induction by Lactobacillus plantarum in the duodenum of healthy humans correlating with immune tolerance

scholarly article

Discovering lactic acid bacteria by genomics

scientific article

Diversity of human small intestinalStreptococcusandVeillonellapopulations ⬇️

scientific article published on April 25, 2013

Draft Genome Sequence of Lactobacillus plantarum SF2A35B.

scientific article published on 25 February 2016

Editorial: Lactic acid bacteria-a continuing journey in science and application

scientific article published on August 2017

Effect of a long-term high-protein diet on survival, obesity development, and gut microbiota in mice

scientific article

Effect of different NADH oxidase levels on glucose metabolism by Lactococcus lactis: kinetics of intracellular metabolite pools determined by in vivo nuclear magnetic resonance

scientific article published on December 2002

Emerging molecular insights into the interaction between probiotics and the host intestinal mucosa ⬇️

scientific article published on November 21, 2011

Engineering lactic acid bacteria for increased industrial functionality ⬇️

scientific article published on March 1, 2011

Engineering of carbon distribution between glycolysis and sugar nucleotide biosynthesis in Lactococcus lactis

scientific article

Enterotypes of the human gut microbiome

scientific article

Enterotypes of the human gut microbiome

scientific article published in Nature

Erratum: Addendum: Enterotypes of the human gut microbiome

scientific article published in Nature

Exopolysaccharides produced by lactic acid bacteria: from health-promoting benefits to stress tolerance mechanisms

scientific article published on 28 March 2016

Exploring Lactobacillus plantarum genome diversity by using microarrays

scientific article

Functional Profiling of Unfamiliar Microbial Communities Using a Validated De Novo Assembly Metatranscriptome Pipeline

scientific article published on 12 January 2016

Functional analysis of four bile salt hydrolase and penicillin acylase family members in Lactobacillus plantarum WCFS1.

scientific article

Functional implications of the microbial community structure of undefined mesophilic starter cultures

scientific article published on 29 August 2014

Genetic characterization of the bile salt response in Lactobacillus plantarum and analysis of responsive promoters in vitro and in situ in the gastrointestinal tract

scientific article published on December 2004

Genome data mining of lactic acid bacteria: the impact of bioinformatics

scientific article

Genome-Wide Prediction and Validation of Sigma70 Promoters in Lactobacillus plantarum WCFS1 ⬇️

scientific article published on September 20, 2012

Genome-wide detection and analysis of cell wall-bound proteins with LPxTG-like sorting motifs

scientific article

Genotypic adaptations associated with prolonged persistence of Lactobacillus plantarum in the murine digestive tract

scientific article

GtfA and GtfB are both required for protein O-glycosylation in Lactobacillus plantarum

scientific article published on 14 February 2014

Gut bacteria-host metabolic interplay during conventionalisation of the mouse germfree colon.

scientific article published on 22 November 2012

Gut microbiota facilitates dietary heme-induced epithelial hyperproliferation by opening the mucus barrier in colon

scientific article published on 27 July 2015

H(2)O(2) production in species of the Lactobacillus acidophilus group: a central role for a novel NADH-dependent flavin reductase

scientific article

High temporal and inter-individual variation detected in the human ileal microbiota

scientific article published in December 2010

High-Resolution Amplified Fragment Length Polymorphism Typing of Lactococcus lactis Strains Enables Identification of Genetic Markers for Subspecies-Related Phenotypes ⬇️

scientific article published on June 10, 2011

High-fat feeding rather than obesity drives taxonomical and functional changes in the gut microbiota in mice

scientific article published on 08 April 2017

High-level production of the low-calorie sugar sorbitol by Lactobacillus plantarum through metabolic engineering

scientific article published on 19 January 2007

IS981-mediated adaptive evolution recovers lactate production by ldhB transcription activation in a lactate dehydrogenase-deficient strain of Lactococcus lactis

scientific article published on August 2003

Identification and genetic characterization of a novel proteinase, PrtR, from the human isolate Lactobacillus rhamnosus BGT10.

scientific article

Identification of Commensal Species Positively Correlated with Early Stress Responses to a Compromised Mucus Barrier

scientific article

Identification of Lactobacillus plantarum genes that are induced in the gastrointestinal tract of mice

scientific article published on September 2004

Identification of genetic loci in Lactobacillus plantarum that modulate the immune response of dendritic cells using comparative genome hybridization

scientific article

Identification of key peptidoglycan hydrolases for morphogenesis, autolysis, and peptidoglycan composition of Lactobacillus plantarum WCFS1

scientific article

Identification of the transcriptional response of human intestinal mucosa to Lactobacillus plantarum WCFS1 in vivo

scientific article

Immunomodulatory properties of Streptococcus and Veillonella isolates from the human small intestine microbiota

scientific article

Impact of 4 Lactobacillus plantarum capsular polysaccharide clusters on surface glycan composition and host cell signaling

scientific article published on 21 November 2012

Impact of Lactobacillus plantarum Sortase on Target Protein Sorting, Gastrointestinal Persistence, and Host Immune Response Modulation ⬇️

scientific article published on November 21, 2012

Increased exopolysaccharide production in Lactococcus lactis due to increased levels of expression of the NIZO B40 eps gene cluster

scientific article

Increased production of folate by metabolic engineering of Lactococcus lactis

scientific article

Indigenous and environmental modulation of frequencies of mutation in Lactobacillus plantarum

scientific article published on 28 December 2009

Intestinal colonisation patterns in breastfed and formula-fed infants during the first 12 weeks of life reveal sequential microbiota signatures

scientific article

Intestinal colonization: how key microbial players become established in this dynamic process: microbial metabolic activities and the interplay between the host and microbes

scientific article

Isolation of DNA from bacterial samples of the human gastrointestinal tract

scientific article published in January 2006

Isolation of RNA from bacterial samples of the human gastrointestinal tract

scientific article published in January 2006

Lactate racemase is a nickel-dependent enzyme activated by a widespread maturation system

scientific article

Lactate racemization as a rescue pathway for supplying D-lactate to the cell wall biosynthesis machinery in Lactobacillus plantarum

scientific article

Lactobacillus plantarum gene clusters encoding putative cell-surface protein complexes for carbohydrate utilization are conserved in specific gram-positive bacteria

scientific article published on 24 May 2006

Lifestyle of Lactobacillus plantarum in the mouse caecum

scientific article

Major role of NAD-dependent lactate dehydrogenases in aerobic lactate utilization in Lactobacillus plantarum during early stationary phase

scientific article published on October 2004

Making sense of quorum sensing in lactobacilli: a special focus on Lactobacillus plantarum WCFS1.

scientific article published on December 2007

Metabolic engineering of Lactococcus lactis: the impact of genomics and metabolic modelling

scientific article

Metabolic engineering of lactic acid bacteria for the production of nutraceuticals

scientific article

Metabolic pathway engineering in lactic acid bacteria ⬇️

scientific article published on April 1, 2003

Metatranscriptome analysis of the human fecal microbiota reveals subject-specific expression profiles, with genes encoding proteins involved in carbohydrate metabolism being dominantly expressed

scientific article

Metatranscriptome analysis of the microbial fermentation of dietary milk proteins in the murine gut.

scientific article

Microarray Analysis and Barcoded Pyrosequencing Provide Consistent Microbial Profiles Depending on the Source of Human Intestinal Samples ⬇️

scientific article published on January 21, 2011

Microbial communities in the human small intestine: coupling diversity to metagenomics

scientific article published on June 2007

Microbial community development in a dynamic gut model is reproducible, colon region specific, and selective for Bacteroidetes and Clostridium cluster IX

scientific article

Microbiome and skin diseases

scientific article

Microbiota conservation and BMI signatures in adult monozygotic twins ⬇️

scientific article published on November 29, 2012

Mining microbial metatranscriptomes for expression of antibiotic resistance genes under natural conditions

scientific article published on 8 July 2015

Modulation of Lactobacillus plantarum gastrointestinal robustness by fermentation conditions enables identification of bacterial robustness markers

scientific article (publication date: 2012)

Molecular signatures for the dynamic process of establishing intestinal host-microbial homeostasis: potential for disease diagnostics?

scientific article

Multifactorial diversity sustains microbial community stability

scientific article

O-glycosylation as a novel control mechanism of peptidoglycan hydrolase activity

scientific article published on 12 June 2013

Omics approaches to study host-microbiota interactions

scientific article

Oxygen relieves the CO2 and acetate dependency of Lactobacillus johnsonii NCC 533

scientific article

Phenotypic and genomic diversity of Lactobacillus plantarum strains isolated from various environmental niches

scientific article

Post-genomics of lactic acid bacteria and other food-grade bacteria to discover gut functionality

scientific article published on April 2004

Potential and opportunities for use of recombinant lactic acid bacteria in human health

scientific article published in January 2004

Probiotic and gut lactobacilli and bifidobacteria: molecular approaches to study diversity and activity

scientific article published on January 2009

Quorum sensing control of lantibiotic production; nisin and subtilin autoregulate their own biosynthesis

scientific article published in September 2004

Recombinant lactic acid bacteria as mucosal biotherapeutic agents ⬇️

scientific article published on June 12, 2011

Regulation of intestinal homeostasis and immunity with probiotic lactobacilli ⬇️

scientific article published on February 26, 2013

Regulation of the metC-cysK operon, involved in sulfur metabolism in Lactococcus lactis

scientific article published on January 2002

Saturated fat stimulates obesity and hepatic steatosis and affects gut microbiota composition by an enhanced overflow of dietary fat to the distal intestine.

scientific article published on 14 June 2012

Selection and characterization of conditionally active promoters in Lactobacillus plantarum, using alanine racemase as a promoter probe

scientific article

Spatial and temporal expression of Lactobacillus plantarum genes in the gastrointestinal tracts of mice

scientific article published on 27 October 2006

Stress Physiology of Lactic Acid Bacteria

scientific article

T lymphocytes control microbial composition by regulating the abundance of Vibrio in the zebrafish gut

scientific article

Temporal and spatial interplay of microbiota and intestinal mucosa drive establishment of immune homeostasis in conventionalized mice

scientific article published on 23 May 2012

The Impact of Lactobacillus plantarum WCFS1 Teichoic Acid D-Alanylation on the Generation of Effector and Regulatory T-cells in Healthy Mice ⬇️

scientific article published on April 30, 2013

The Lactobacillus plantarum ftsH gene is a novel member of the CtsR stress response regulon

scientific article published on 12 December 2008

The extracellular biology of the lactobacilli

scientific article published on 19 January 2010

The gut microbiota elicits a profound metabolic reorientation in the mouse jejunal mucosa during conventionalisation

scientific article

The human gut microbiome: are we our enterotypes? ⬇️

scientific article published on September 1, 2011

The human small intestinal microbiota is driven by rapid uptake and conversion of simple carbohydrates

scientific article

The proceedings of the Tenth Symposium on Lactic Acid Bacteria

scientific article published on 30 August 2011

The quest for probiotic effector molecules--unraveling strain specificity at the molecular level

scientific article published on 08 October 2012

The small intestine microbiota, nutritional modulation and relevance for health

scientific article

Towards microbial fermentation metabolites as markers for health benefits of prebiotics

scientific article published on June 2015

Towards understanding molecular modes of probiotic action

scientific article

Transcriptomes reveal genetic signatures underlying physiological variations imposed by different fermentation conditions in Lactobacillus plantarum

scientific article (publication date: 2012)

Two arginine repressors regulate arginine biosynthesis in Lactobacillus plantarum

scientific article published on September 2004

Use of the alr gene as a food-grade selection marker in lactic acid bacteria

scientific article

sigma54-Mediated control of the mannose phosphotransferase sytem in Lactobacillus plantarum impacts on carbohydrate metabolism

scientific article

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