List of works by Adrian S. Woolf

22q11.2 duplications in a UK cohort with bladder exstrophy-epispadias complex

scientific article published on 09 January 2019

A characterization of the chloride conductance in mesangial cells from the H-2Kb-tsA58 transgenic mouse

scientific article published on 01 November 1995

A molecular and genetic view of human renal and urinary tract malformations.

scientific article

A paradoxical teratogenic mechanism for retinoic acid.

scientific article

ACTB Loss-of-Function Mutations Result in a Pleiotropic Developmental Disorder.

scientific article published in December 2017

Albuminuria is associated with too few glomeruli and too much testosterone

scientific article published on 27 February 2013

Analysis of TSHZ2 and TSHZ3 genes in congenital pelvi-ureteric junction obstruction

scientific article published on 10 September 2009

Angiogenesis and autosomal dominant polycystic kidney disease.

scientific article published on 19 September 2012

Angiopoietin correlates with glomerular capillary loss in anti-glomerular basement membrane glomerulonephritis

scientific article published in June 2002

Angiopoietin growth factors and Tie receptor tyrosine kinases in renal vascular development.

scientific article

Angiopoietin-1 therapy enhances fibrosis and inflammation following folic acid-induced acute renal injury.

scientific article published on 14 May 2008

Angiopoietins: vascular growth factors looking for roles in glomeruli.

scientific article published on January 2010

Autosomal dominant inheritance of non-syndromic renal hypoplasia and dysplasia: dramatic variation in clinical severity in a single kindred

scientific article published on 18 October 2006

Bridging the gap: functional healing of embryonic small intestine ex vivo

scientific article

Ca2+ regulation in detrusor smooth muscle from ovine fetal bladder after in utero bladder outflow obstruction

scientific article published on 01 February 2007

Cell biology of ureter development.

scientific article

Circulating angiopoietin-2 is a marker for early cardiovascular disease in children on chronic dialysis

scientific article

Coinheritance of COL4A5 and MYO1E mutations accentuate the severity of kidney disease

scientific article

Congenital Disorders of the Human Urinary Tract: Recent Insights From Genetic and Molecular Studies

scientific article published on 11 April 2019

Congential obstructive nephropathy gets complicated

scientific article published on 01 February 2003

Corticosteroid-induced kidney dysmorphogenesis is associated with deregulated expression of known cystogenic molecules, as well as Indian hedgehog

scientific article published on 9 December 2009

Cytokeratin 15 marks basal epithelia in developing ureters and is upregulated in a subset of urothelial cell carcinomas

scientific article

De Novo Uroplakin IIIa Heterozygous Mutations Cause Human Renal Adysplasia Leading to Severe Kidney Failure

scientific article published on 11 May 2005

Development of embryonic stem cells in recombinant kidneys

scientific article published on October 2012

Diabetes, genes, and kidney development

scientific article published on 01 March 2000

Disruption of ROBO2 is associated with urinary tract anomalies and confers risk of vesicoureteral reflux

scientific article

Do kidney tubules serve an angiogenic soup?

scientific article published on 01 August 2004

Does atrial natriuretic factor contribute to the progression of renal disease?

scientific article published on April 1990

Dysfunctional bladder neurophysiology in urofacial syndrome Hpse2 mutant mice

scientific article published on 01 July 2020

Effects of oxygen on vascular patterning in Tie1/LacZ metanephric kidneys in vitro

scientific article published in June 1998

Emerging roles of obstruction and mutations in renal malformations

scientific article published on 01 October 1998

Encephalopathy in patient taking aluminium-containing agents, including sucralfate

scientific article published on 01 September 1989

Evolving concepts in human renal dysplasia

scientific article published on April 2004

Ex vivo modeling of chemical synergy in prenatal kidney cystogenesis

scientific article

Exogenous transforming growth factor-β1 enhances smooth muscle differentiation in embryonic mouse jejunal explants.

scientific article published on 13 January 2017

Experimental short-term partial fetal bladder outflow obstruction: II. Compliance and contractility associated with urinary flow impairment

scientific article published on 09 May 2006

Expression of Fraser syndrome genes in normal and polycystic murine kidneys.

scientific article published on 13 October 2011

Extracellular matrix protein expression during mouse detrusor development

scientific article published on 01 January 2003

Formation of Mature Nephrons by Implantation of Human Pluripotent Stem Cell-Derived Progenitors into Mice

scientific article published on 01 January 2020

Fras1, a basement membrane-associated protein mutated in Fraser syndrome, mediates both the initiation of the mammalian kidney and the integrity of renal glomeruli

scientific article published on 11 September 2008

Fraser syndrome and mouse blebbed phenotype caused by mutations in FRAS1/Fras1 encoding a putative extracellular matrix protein

scientific article

From gene discovery to new biological mechanisms: heparanases and congenital urinary bladder disease

scientific article

From human pluripotent stem cells to functional kidney organoids and models of renal disease

scientific article published on 21 July 2018

Functional molecules in mesothelial-to-mesenchymal transition revealed by transcriptome analyses

scientific article published on 04 July 2018

GENES ASSOCIATED WITH BLOOD PRESSURE TRAITS SHOW CELL TYPE-SPECIFIC EXPRESSION AND CONTROL MULTIPLE CAUSAL LINKS TO BLOOD PRESSURE REGULATION IN THE HUMAN KIDNEY

scientific article published in 2021

Generation of Functioning Nephrons by Implanting Human Pluripotent Stem Cell-Derived Kidney Progenitors

scientific article published on 7 February 2018

Generation of mice with a conditional null Fraser syndrome 1 (Fras1) allele

scientific article published on 23 July 2012

Genetic Background is a Key Determinant of Glomerular Extracellular Matrix Composition and Organization

scientific article

Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract.

scientific article published on 24 January 2009

Genetically engineered kidneys

scientific article

Genome-wide linkage and association study implicates the 10q26 region as a major genetic contributor to primary nonsyndromic vesicoureteric reflux

scientific article published on 6 November 2017

Growing a new human kidney

scientific article published on 25 May 2019

Growth factors in the pathogenesis of renovascular complications of diabetes mellitus

scientific article published on April 1, 1992

HNF1B Mutations Are Associated With a Gitelman-like Tubulopathy That Develops During Childhood

scientific article published on 29 May 2019

HNF1B mutations associate with hypomagnesemia and renal magnesium wasting

scientific article

Heparanase 2, mutated in urofacial syndrome, mediates peripheral neural development in Xenopus

scientific article published on April 2014

Hypertension and renin-angiotensin system blockers are not associated with expression of angiotensin-converting enzyme 2 (ACE2) in the kidney

scientific article published on 27 October 2020

ISL1 is a major susceptibility gene for classic bladder exstrophy and a regulator of urinary tract development

scientific article published on 08 February 2017

Identification of a new gene mutated in Fraser syndrome and mouse myelencephalic blebs

scientific article (publication date: May 2005)

Immunohistochemical analysis of Sonic hedgehog signalling in normal human urinary tract development

scientific article

Immunolocalization of cystinosin, the protein defective in cystinosis

scientific article

International multi-centre study of pregnancy outcomes with interleukin-1 inhibitors.

scientific article published on 23 August 2017

KAL, a gene mutated in Kallmann's syndrome, is expressed in the first trimester of human development.

scientific article published in April 1995

LRIG2 mutations cause urofacial syndrome

scientific article

Lack of major involvement of human uroplakin genes in vesicoureteral reflux: implications for disease heterogeneity

scientific article

Loss-of-function variants in myocardin cause congenital megabladder in humans and mice

scientific article published on 01 December 2019

Lrig2 and Hpse2, mutated in urofacial syndrome, pattern nerves in the urinary bladder

scientific article published on 08 March 2019

Measures of kidney function by minimally invasive techniques correlate with histological glomerular damage in SCID mice with adriamycin-induced nephropathy

scientific article

Medical versus surgical treatment in children with severe bilateral vesicoureteric reflux and bilateral nephropathy: a randomised trial

scientific article

Microarray interrogation of human metanephric mesenchymal cells highlights potentially important molecules in vivo.

scientific article published on 19 September 2006

Molecular bases of human kidney malformations

scientific article published on June 1997

Molecular insights into genome-wide association studies of chronic kidney disease-defining traits

scientific article published in Nature Communications

Muscarinic Acetylcholine Receptor M3 Mutation Causes Urinary Bladder Disease and a Prune-Belly-like Syndrome

scientific article published on November 2011

Mutation analyses of Uroplakin II in children with renal tract malformations

scientific article

Mutational analyses of UPIIIA, SHH, EFNB2 and HNF1beta in persistent cloaca and associated kidney malformations

scientific article

Mutations in HPSE2 Cause Urofacial Syndrome

scientific article published in August 2010

Mutations in HPSE2 cause urofacial syndrome

scientific article

Mutations in TBX18 Cause Dominant Urinary Tract Malformations via Transcriptional Dysregulation of Ureter Development

scientific article

Mutations in the hepatocyte nuclear factor-1beta gene are associated with familial hypoplastic glomerulocystic kidney disease

scientific article

Oral-facial-digital syndrome type 1 is another dominant polycystic kidney disease: clinical, radiological and histopathological features of a new kindred.

scientific article

Overactivity or blockade of transforming growth factor-β each generate a specific ureter malformation

scientific article published on 01 October 2019

Perinatal renal disease

scientific article published on 21 December 2007

Perspectives on human perinatal renal tract disease.

scientific article published on 13 November 2007

Physiological release of atrial natriuretic peptide in heart transplant recipient

scientific article published on 01 July 1987

Pinpointing clinical diagnosis through whole exome sequencing to direct patient care: a case of Senior-Loken syndrome

scientific article published in The Lancet

Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning

scientific article published on 02 September 2016

Podocyte-specific expression of angiopoietin-2 causes proteinuria and apoptosis of glomerular endothelia

scientific article published on 11 July 2007

Potassium conductances and proliferation in conditionally immortalized renal glomerular mesangial cells from the H-2Kb-tsA58 transgenic mouse

scientific article published on February 1997

Primary vesicoureteric reflux as a predictor of renal damage in children hospitalized with urinary tract infection: a systematic review and meta-analysis

scientific article

Primary, nonsyndromic vesicoureteric reflux and nephropathy in sibling pairs: a United Kingdom cohort for a DNA bank

scientific article

Protein restriction in pregnancy is associated with increased apoptosis of mesenchymal cells at the start of rat metanephrogenesis.

scientific article published in April 2002

Proteinuria, hypertension and chronic renal failure in X-linked Kallmann's syndrome, a defined genetic cause of solitary functioning kidney

scientific article published in August 1998

Publisher Correction: Genome-wide linkage and association study implicates the 10q26 region as a major genetic contributor to primary nonsyndromic vesicoureteric reflux

scientific article

RET gene mutations are not a common cause of congenital solitary functioning kidney in adults

scientific article published on April 2009

Radiotelemetered urodynamics of obstructed ovine fetal bladders: correlations with ex vivo cystometry and renal histopathology

scientific article published on 12 March 2007

Rare Variants in BNC2 Are Implicated in Autosomal-Dominant Congenital Lower Urinary-Tract Obstruction

scientific article published on 01 May 2019

Recent insights into kidney diseases associated with glomerular cysts.

scientific article

Renal FMD may not confer a familial hypertensive risk nor is it caused by ACTA2 mutations

scientific article published on 08 May 2011

Renal hypoplasia and dysplasia: starting to put the puzzle together

scientific article published on 07 September 2006

Representing kidney development using the gene ontology

scientific article

Roles of growth factors in renal development.

scientific article published on January 1997

Severe hyperglycemia after renal transplantation in a pediatric patient with a mutation of the hepatocyte nuclear factor-1beta gene

scientific article published on 01 December 2002

Similar renal outcomes in children with ADPKD diagnosed by screening or presenting with symptoms.

scientific article published on 05 August 2010

Solitary functioning kidney and diverse genital tract malformations associated with hepatocyte nuclear factor-1beta mutations

scientific article

Spatiotemporal dynamics and heterogeneity of renal lymphatics in mammalian development and cystic kidney disease

scientific article published on 06 December 2019

Sprouty1 haploinsufficiency prevents renal agenesis in a model of Fraser syndrome.

scientific article

Systemic lupus erythematosus and primary cerebral lymphoma.

scientific article published on July 1987

TSHZ3 deletion causes an autism syndrome and defects in cortical projection neurons

scientific article

Targeted glomerular angiopoietin-1 therapy for early diabetic kidney disease.

scientific article published on 5 September 2013

Taxol inhibits progression of congenital polycystic kidney disease

scientific article published in Nature

Teashirt 3 is necessary for ureteral smooth muscle differentiation downstream of SHH and BMP4

scientific journal article

The P2X7 ATP receptor modulates renal cyst development in vitro

scientific article

The oral-facial-digital syndrome type 1 (OFD1), a cause of polycystic kidney disease and associated malformations, maps to Xp22.2-Xp22.3.

scientific article

The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation

scientific journal article

Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics

scientific article published on 01 March 2019

Unilateral multicystic dysplastic kidney

scientific article published on 01 January 2006

Unraveling the genetic landscape of bladder development in mice.

scientific article published on 19 March 2009

Urinary tract effects of HPSE2 mutations

scientific article

Urofacial syndrome: a genetic and congenital disease of aberrant urinary bladder innervation.

scientific article published on 09 July 2013

Uroplakins: new molecular players in the biology of urinary tract malformations.

scientific article published on 20 December 2006

Using stem and progenitor cells to recapitulate kidney development and restore renal function

scientific article published on April 2014

Vangl2, a planar cell polarity molecule, is implicated in irreversible and reversible kidney glomerular injury

scientific article published on 01 December 2018

Vascular Endothelial Growth Factor C for Polycystic Kidney Diseases

scientific article

Vascular endothelial growth factor administration does not improve microvascular disease in the salt-dependent phase of post-angiotensin II hypertension

scientific article published on 27 June 2006

Vascular endothelial growth factor mediates hypoxic stimulated embryonic bladder growth in organ culture

scientific article published on 01 April 2007

Vascular endothelial growth factor stimulates embryonic urinary bladder development in organ culture

scientific article published on 01 July 2006

Vascular growth factors play critical roles in kidney glomeruli

scientific article published on December 2015

Whole-genome linkage and association scan in primary, nonsyndromic vesicoureteric reflux

scientific article

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