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List of works by Thierry Roger

A candidate HIV/AIDS vaccine (MVA-B) lacking vaccinia virus gene C6L enhances memory HIV-1-specific T-cell responses

scientific article published in 2011

A functional microsatellite of the macrophage migration inhibitory factor gene associated with meningococcal disease

scientific article published on 11 October 2011

A new class of isothiocyanate-based irreversible inhibitors of macrophage migration inhibitory factor

scientific article published in October 2009

Adiponectin and heme oxygenase-1 suppress TLR4/MyD88-independent signaling in rat Kupffer cells and in mice after chronic ethanol exposure.

scientific article published on 22 September 2010

Angiotensin II upregulates toll-like receptor 4 on mesangial cells

scientific article published on 4 May 2006

Author Correction: Transmission of trained immunity and heterologous resistance to infections across generations

scientific article published in 2023

Autoreactive T cells in normal mice: unrestricted recognition of self peptides on dendritic cell I-A molecules by CD4-CD8- T cell receptor alpha/beta+ T cell clones expressing V beta 8.1 gene segments.

scientific article published in June 1990

Basic calcium phosphate crystals induce monocyte/macrophage IL-1β secretion through the NLRP3 inflammasome in vitro.

scientific article published on 14 January 2011

Biliverdin inhibits Toll-like receptor-4 (TLR4) expression through nitric oxide-dependent nuclear translocation of biliverdin reductase ⬇️

scientific article published on October 31, 2011

Caspase-8-dependent gasdermin D cleavage promotes antimicrobial defense but confers susceptibility to TNF-induced lethality

scientific article published on 18 November 2020

Co-selection of the rare T cell receptor-gamma B haplotype in mouse lines selected for low responsiveness to red blood cell antigens.

scientific article

Correction: Systems Analysis of MVA-C Induced Immune Response Reveals Its Significance as a Vaccine Candidate against HIV/AIDS of Clade C

scientific article published in PLoS ONE

Correction: Systems Analysis of MVA-C Induced Immune Response Reveals Its Significance as a Vaccine Candidate against HIV/AIDS of Clade C.

scientific article published on 17 May 2012

Critical role for Ets, AP-1 and GATA-like transcription factors in regulating mouse Toll-like receptor 4 (Tlr4) gene expression

scientific article

Critical role of endogenous Mtv in acute lethal graft-versus-host disease

scientific article published on 01 February 1995

Deletion of the vaccinia virus gene A46R, encoding for an inhibitor of TLR signalling, is an effective approach to enhance the immunogenicity in mice of the HIV/AIDS vaccine candidate NYVAC-C

scientific article (publication date: 2013)

Deletion of the viral anti-apoptotic gene F1L in the HIV/AIDS vaccine candidate MVA-C enhances immune responses against HIV-1 antigens

scientific article

Differential regulation of Toll-like receptor 4 gene expression in renal cells by angiotensin II: dependency on AP1 and PU.1 transcriptional sites.

scientific article published on 8 May 2007

Emerging single-cell technologies in immunology

scientific article published on 23 April 2015

Estradiol and progesterone strongly inhibit the innate immune response of mononuclear cells in newborns

scientific article

Exaggerated IL-8 and IL-6 responses to TNF-alpha by parainfluenza virus type 4-infected NCI-H292 cells

scientific article published on 23 July 2004

Exhaustion of bacteria-specific CD4 T cells and microbial translocation in common variable immunodeficiency disorders

scientific article published on 15 September 2014

Expression and function of macrophage migration inhibitory factor (MIF) in melioidosis

scientific article

FBXW7α attenuates inflammatory signalling by downregulating C/EBPδ and its target gene Tlr4.

scientific article published on January 2013

Frequent Occupational Exposure to Fusarium Mycotoxins of Workers in the Swiss Grain Industry

scientific article

Functional polymorphisms of macrophage migration inhibitory factor as predictors of morbidity and mortality of pneumococcal meningitis

scientific article published on 14 March 2016

Glucocorticoid-induced MIF expression by human CEM T cells

scientific article published on 30 July 2009

Hepatitis B virus e antigen physically associates with receptor-interacting serine/threonine protein kinase 2 and regulates IL-6 gene expression.

scientific article published on 21 May 2012

Hepatitis C Virus nonstructural 5A protein inhibits lipopolysaccharide-mediated apoptosis of hepatocytes by decreasing expression of Toll-like receptor 4.

scientific article published in September 2011

High expression levels of macrophage migration inhibitory factor sustain the innate immune responses of neonates

scientific article published on 8 February 2016

Histone acetyltransferase HBO1 inhibits NF-kappaB activity by coactivator sequestration

scientific article published on 18 September 2006

Histone deacetylase inhibitors impair antibacterial defenses of macrophages.

scientific article

Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection

scientific article published on 18 October 2010

Histone deacetylase inhibitors repress macrophage migration inhibitory factor (MIF) expression by targeting MIF gene transcription through a local chromatin deacetylation.

scientific article published on 10 September 2009

IL-6 protein production by airway epithelial(-like) cells disabled in IL-6 mRNA degradation

scientific article published on 01 August 2000

IL28B expression depends on a novel TT/-G polymorphism which improves HCV clearance prediction

scientific article published on 27 May 2013

IRF5 Is a Key Regulator of Macrophage Response to Lipopolysaccharide in Newborns

scientific article published on 11 July 2018

Identification and characterization of novel classes of macrophage migration inhibitory factor (MIF) inhibitors with distinct mechanisms of action

scientific article

Immune responses to airborne fungi and non-invasive airway diseases

scientific article

Impact of the Dual Deletion of the Mitochondrial Sirtuins SIRT3 and SIRT5 on Anti-microbial Host Defenses

scientific article published on 01 October 2019

Impact of the microbial derived short chain fatty acid propionate on host susceptibility to bacterial and fungal infections in vivo

scientific article

Increased macrophage migration inhibitory factor (MIF) plasma levels in acute HIV-1 infection

article

Initial responses to endotoxins and Gram-negative bacteria

scientific article

Innate Immune Sensing of Fusarium culmorum by Mouse Dendritic Cells.

scientific article published on January 2015

Innate immune defects in HIV permissive cell lines.

scientific article published on 27 June 2016

Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome

scientific article

Interleukin-1- and type I interferon-dependent enhanced immunogenicity of an NYVAC-HIV-1 Env-Gag-Pol-Nef vaccine vector with dual deletions of type I and type II interferon-binding proteins

scientific article

Involvement of nuclear factor-kappaB in macrophage migration inhibitory factor gene transcription up-regulation induced by interleukin- 1 beta in ectopic endometrial cells

scientific article published on 16 August 2008

Lack of Mycobacterium tuberculosis-specific interleukin-17A-producing CD4+ T cells in active disease

scientific article published on 6 March 2013

Le facteur d’inhibition de la migration des macrophages (MIF), un régulateur de la réponse immunitaire innée néonatale

scientific article published on 01 December 2016

MIF regulates innate immune responses through modulation of Toll-like receptor 4

article

Macrophage Migration Inhibitory Factor and Host Innate Immune Defenses against Bacterial Sepsis

scientific article published on 01 June 2003

Macrophage migration inhibitory factor (MIF): mechanisms of action and role in disease

scientific article (publication date: April 2002)

Macrophage migration inhibitory factor deficiency is associated with impaired killing of gram-negative bacteria by macrophages and increased susceptibility to Klebsiella pneumoniae sepsis

scientific article

Macrophage migration inhibitory factor deficiency leads to age-dependent impairment of glucose homeostasis in mice

scientific article published on 21 June 2010

Macrophage migration inhibitory factor is involved in a positive feedback loop increasing aromatase expression in endometriosis

scientific article published on 30 June 2012

Macrophage migration inhibitory factor is overproduced through EGR1 in TET2<sup>low</sup> resting monocytes

scientific article published on 03 February 2022

Macrophage migration inhibitory factor promotes innate immune responses by suppressing glucocorticoid-induced expression of mitogen-activated protein kinase phosphatase-1.

scientific article published on December 2005

Macrophage migration inhibitory factor regulates TLR4 expression and modulates TCR/CD3-mediated activation in CD4+ T lymphocytes

scientific article published on 28 June 2019

Macrophage migration inhibitory factor: a regulator of innate immunity ⬇️

scientific article (publication date: October 2003)

Macrophage migration inhibitory factor: gene polymorphisms and susceptibility to inflammatory diseases

scientific article

Mechanisms that potentially underlie virus-induced exaggerated inflammatory responses by airway epithelial cells.

scientific article

Modulation of human memory T-cell function by different antigen-presenting cells

scientific article published on 20 December 2011

Mouse Model of Respiratory Tract Infection Induced by Waddlia chondrophila.

scientific article

Myeloid-Derived Suppressor Cells in Sepsis

scientific article published on 27 February 2019

Neutralization of macrophage migration inhibitory factor (MIF) by fully human antibodies correlates with their specificity for the β-sheet structure of MIF.

scientific article

Novel strategies for targeting innate immune responses to influenza.

scientific article published on 27 January 2016

Pancreatic stone protein as a novel marker for neonatal sepsis

scientific article published on 8 January 2013

Plasma Levels of Macrophage Migration Inhibitory Factor and d-Dopachrome Tautomerase Show a Highly Specific Profile in Early Life

scientific article published on 25 January 2017

Polymorphism of Tcrb and Tcrg genes in Biozzi mice: segregation analysis of a new Tcrg haplotype with antibody responsiveness

scientific article published on 01 January 1990

Polymorphism of the Tcrg-V1-V2 region in mice: identification of a new Vg1 allele in DBA/2.

scientific article

Preferential V delta 1 expression among TcR gamma/delta-bearing T cells in human oral epithelium

scientific article published on 01 March 1993

Primary and Immortalized Human Respiratory Cells Display Different Patterns of Cytotoxicity and Cytokine Release upon Exposure to Deoxynivalenol, Nivalenol and Fusarenon-X.

scientific article published on 25 October 2017

Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4.

scholarly article

Rapid and transient activation of the ERK MAPK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on JAB1/CSN5 and Src kinase activity

scientific article published on 24 August 2005

Rearrangement by chromosomal inversion in the T cell receptor gamma locus in a murine alpha beta T cell clone

scientific article published in December 1993

Regulation of constitutive and microbial pathogen-induced human macrophage migration inhibitory factor (MIF) gene expression

scientific article published on December 2007

Regulation of human lung adenocarcinoma cell migration and invasion by macrophage migration inhibitory factor

scientific article published on 20 August 2007

Release of macrophage migration inhibitory factor by neuroendocrine-differentiated LNCaP cells sustains the proliferation and survival of prostate cancer cells.

scientific article

Reply to: ‘Lack of evidence for intergenerational inheritance of immune resistance to infections’

scientific article published in 2022

Resistance to collagen-induced arthritis in Biozzi mice is not associated with T cell receptor V beta gene polymorphism.

scientific article

Role of MyD88 and Toll-like receptors 2 and 4 in the sensing of Parachlamydia acanthamoebae

scientific article

Role of TLR1, TLR2 and TLR6 in the modulation of intestinal inflammation and Candida albicans elimination

scientific article published on 15 February 2017

Screening the Impact of Sirtuin Inhibitors on Inflammatory and Innate Immune Responses of Macrophages and in a Mouse Model of Endotoxic Shock.

scientific article published on January 2016

Sirtuin 3 deficiency does not alter host defenses against bacterial and fungal infections

scientific article

Sirtuin 5 Deficiency Does Not Compromise Innate Immune Responses to Bacterial Infections

article

Species-specific recognition of Aspergillus fumigatus by Toll-like receptor 1 and Toll-like receptor 6.

scientific article published on 7 February 2012

Study of Early Elevated Gas6 Plasma Level as a Predictor of Mortality in a Prospective Cohort of Patients with Sepsis

scientific article

Superinduction of interleukin-6 mRNA in lung epithelial H292 cells depends on transiently increased C/EBP activity and durable increased mRNA stability

scientific article published on July 1998

Systems analysis of MVA-C induced immune response reveals its significance as a vaccine candidate against HIV/AIDS of clade C.

scientific article

T(H)17 cells promote microbial killing and innate immune sensing of DNA via interleukin 26

scientific article

TLR2-mediated neutrophil depletion exacerbates bacterial sepsis

scholarly article

Targeting toll-like receptors: promising therapeutic strategies for the management of sepsis-associated pathology and infectious diseases

scientific article

The Anticancer Peptide TAT-RasGAP317-326 Exerts Broad Antimicrobial Activity.

scientific article

The dexamethasone-induced inhibition of proliferation, migration, and invasion in glioma cell lines is antagonized by macrophage migration inhibitory factor (MIF) and can be enhanced by specific MIF inhibitors

scientific article

The fungal ligand chitin directly binds TLR2 and triggers inflammation dependent on oligomer size

scientific article published on 18 October 2018

The glucocorticoid-induced leucine zipper (gilz/Tsc22d3-2) gene locus plays a crucial role in male fertility

scientific article

The role of macrophage migration inhibitory factor in mouse islet transplantation

scientific article published in November 2008

The sirtuin inhibitor cambinol impairs MAPK signaling, inhibits inflammatory and innate immune responses and protects from septic shock.

scientific article

The tumor suppressor CYLD interacts with TRIP and regulates negatively nuclear factor kappaB activation by tumor necrosis factor

scientific article

Toll-Like Receptor 4 (TLR4) and Triggering Receptor Expressed on Myeloid Cells-2 (TREM-2) Activation Balance Astrocyte Polarization into a Proinflammatory Phenotype.

scientific article published on 25 May 2017

Transmission of trained immunity and heterologous resistance to infections across generations

scientific article published in 2021

Tumour necrosis factor-alpha up-regulates macrophage migration inhibitory factor expression in endometrial stromal cells via the nuclear transcription factor NF-kappaB.

scientific article

Use of a human-like low-grade bacteremia model of experimental endocarditis to study the role of Staphylococcus aureus adhesins and platelet aggregation in early endocarditis

scientific article published on 17 December 2012

Virological and immunological characterization of novel NYVAC-based HIV/AIDS vaccine candidates expressing clade C trimeric soluble gp140(ZM96) and Gag(ZM96)-Pol-Nef(CN54) as virus-like particles.

scientific article

Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation.

scientific article

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