List of works - Caroline Smet

50nm-scale localization of single unmodified, isotopically enriched, proteins in cells

scientific article

A TDG/CBP/RARα ternary complex mediates the retinoic acid-dependent expression of DNA methylation-sensitive genes

scientific article

A functional fragment of Tau forms fibers without the need for an intermolecular cysteine bridge

scientific article published in 2014

Accepting its Random Coil Nature Allows a Partial NMR Assignment of the Neuronal Tau Protein

scholarly article by Caroline Smet published in November 2004

Cell signaling, post-translational protein modifications and NMR spectroscopy

scientific article

Control of protein-protein interactions: structure-based discovery of low molecular weight inhibitors of the interactions between Pin1 WW domain and phosphopeptides

scientific article published on July 2005

Direct Crosstalk Between -GlcNAcylation and Phosphorylation of Tau Protein Investigated by NMR Spectroscopy

Exploring the molecular function of PIN1 by nuclear magnetic resonance

scientific article published on June 2006

From Epigenomic to Morphogenetic Emergence

Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylation

scientific article

Identification of the Tau phosphorylation pattern that drives its aggregation

scientific article published on 7 August 2017

Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice

scientific article (publication date: 2013)

Interplay between troponin T phosphorylation and O-N-acetylglucosaminylation in ischaemic heart failure

scientific article

Involvement of 14-3-3 in tubulin instability and impaired axon development is mediated by Tau

scientific article

Major Differences between the Self-Assembly and Seeding Behavior of Heparin-Induced and in Vitro Phosphorylated Tau and Their Modulation by Potential Inhibitors

scientific article published on 21 June 2019

Molecular basis for an ancient partnership between prolyl isomerase Pin1 and phosphatase inhibitor-2

scientific article

Molecular implication of PP2A and Pin1 in the Alzheimer's disease specific hyperphosphorylation of Tau.

scientific article

Molecular mechanisms of the phospho-dependent prolyl cis/trans isomerase Pin1.

scientific article published on 24 September 2007

NMR Meets Tau: Insights into Its Function and Pathology

scientific article

NMR spectroscopy of the neuronal tau protein: normal function and implication in Alzheimer's disease

scientific article published on August 2010

NMR-based detection of acetylation sites in peptides

scientific article published on August 2010

Native Top-Down Mass Spectrometry and Ion Mobility Spectrometry of the Interaction of Tau Protein with a Molecular Tweezer Assembly Modulator

scientific article published on 30 July 2018

Neurofibrillary degeneration of the Alzheimer-type: an alternate pathway to neuronal apoptosis?

scientific article

Nuclear Magnetic Resonance Analysis of the Acetylation Pattern of the Neuronal Tau Protein

article

Nuclear Magnetic Resonance Spectroscopy for the Identification of Multiple Phosphorylations of Intrinsically Disordered Proteins

scientific article published on 27 December 2016

Nuclear magnetic resonance spectroscopy characterization of interaction of Tau with DNA and its regulation by phosphorylation

scientific article published on 09 February 2015

Pin1: a therapeutic target in Alzheimer neurodegeneration

scientific article published on December 2002

Proline Conformation in a Functional Tau Fragment

scientific article published on 2 December 2015

Proline-directed random-coil chemical shift values as a tool for the NMR assignment of the tau phosphorylation sites

scientific article published in January 2004

Regulation of Pin1 peptidyl-prolylcis/transisomerase activity by its WW binding module on a multi-phosphorylated peptide of Tau protein

scholarly article by Caroline Smet published in July 2005

SUMO-1 possesses DNA binding activity

scientific article

SUMO-1 regulates the conformational dynamics of thymine-DNA Glycosylase regulatory domain and competes with its DNA binding activity

scientific article

Semi-synthesis of a tag-free O-GlcNAcylated tau protein by sequential chemoselective ligation.

scientific article

Structure and plasticity of the peptidyl-prolyl isomerase Par27 of Bordetella pertussis revealed by X-ray diffraction and small-angle X-ray scattering.

scientific article published on 20 November 2009

Studying the natively unfolded neuronal Tau protein by solution NMR spectroscopy

scientific article

Tag-Free Semi-Synthesis of the Tau Protein.

scientific article published in January 2017

Tau pathology modulates Pin1 post-translational modifications and may be relevant as biomarker

scientific article published on 25 August 2012

The O-β-linked N-acetylglucosaminylation of the Lamin B receptor and its impact on DNA binding and phosphorylation

scientific article published on 11 January 2018

The Peptidyl–Prolyl Isomerase and Chaperone Par27 of Bordetella pertussis as the Prototype for a New Group of Parvulins

scientific article published on 09 November 2007

The Study of Posttranslational Modifications of Tau Protein by Nuclear Magnetic Resonance Spectroscopy: Phosphorylation of Tau Protein by ERK2 Recombinant Kinase and Rat Brain Extract, and Acetylation by Recombinant Creb-Binding Protein

scientific article published in January 2017

The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention?

scientific article published on 01 March 2019

The peptidyl prolyl cis/trans-isomerase Pin1 recognizes the phospho-Thr212-Pro213 site on Tau.

scientific article published in February 2004

The thymine-DNA glycosylase regulatory domain: residual structure and DNA binding

scientific journal article

Traceless purification and desulfurization of tau protein ligation products

scientific article published on 17 November 2014

Unraveling a phosphorylation event in a folded protein by NMR spectroscopy: phosphorylation of the Pin1 WW domain by PKA.

scientific article published on 2 March 2013

List of works by Caroline Smet

50nm-scale localization of single unmodified, isotopically enriched, proteins in cells

A TDG/CBP/RARα ternary complex mediates the retinoic acid-dependent expression of DNA methylation-sensitive genes

A functional fragment of Tau forms fibers without the need for an intermolecular cysteine bridge

Accepting its Random Coil Nature Allows a Partial NMR Assignment of the Neuronal Tau Protein

Cell signaling, post-translational protein modifications and NMR spectroscopy

Control of protein-protein interactions: structure-based discovery of low molecular weight inhibitors of the interactions between Pin1 WW domain and phosphopeptides

Direct Crosstalk Between -GlcNAcylation and Phosphorylation of Tau Protein Investigated by NMR Spectroscopy

Exploring the molecular function of PIN1 by nuclear magnetic resonance

From Epigenomic to Morphogenetic Emergence

Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylation

Identification of the Tau phosphorylation pattern that drives its aggregation

Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice

Interplay between troponin T phosphorylation and O-N-acetylglucosaminylation in ischaemic heart failure

Involvement of 14-3-3 in tubulin instability and impaired axon development is mediated by Tau

Major Differences between the Self-Assembly and Seeding Behavior of Heparin-Induced and in Vitro Phosphorylated Tau and Their Modulation by Potential Inhibitors

Molecular basis for an ancient partnership between prolyl isomerase Pin1 and phosphatase inhibitor-2

Molecular implication of PP2A and Pin1 in the Alzheimer's disease specific hyperphosphorylation of Tau.

Molecular mechanisms of the phospho-dependent prolyl cis/trans isomerase Pin1.

NMR Meets Tau: Insights into Its Function and Pathology

NMR spectroscopy of the neuronal tau protein: normal function and implication in Alzheimer's disease

NMR-based detection of acetylation sites in peptides

Native Top-Down Mass Spectrometry and Ion Mobility Spectrometry of the Interaction of Tau Protein with a Molecular Tweezer Assembly Modulator

Neurofibrillary degeneration of the Alzheimer-type: an alternate pathway to neuronal apoptosis?

Nuclear Magnetic Resonance Analysis of the Acetylation Pattern of the Neuronal Tau Protein

Nuclear Magnetic Resonance Spectroscopy for the Identification of Multiple Phosphorylations of Intrinsically Disordered Proteins

Nuclear magnetic resonance spectroscopy characterization of interaction of Tau with DNA and its regulation by phosphorylation

Pin1: a therapeutic target in Alzheimer neurodegeneration

Proline Conformation in a Functional Tau Fragment

Proline-directed random-coil chemical shift values as a tool for the NMR assignment of the tau phosphorylation sites

Regulation of Pin1 peptidyl-prolylcis/transisomerase activity by its WW binding module on a multi-phosphorylated peptide of Tau protein

SUMO-1 possesses DNA binding activity

SUMO-1 regulates the conformational dynamics of thymine-DNA Glycosylase regulatory domain and competes with its DNA binding activity

Semi-synthesis of a tag-free O-GlcNAcylated tau protein by sequential chemoselective ligation.

Structure and plasticity of the peptidyl-prolyl isomerase Par27 of Bordetella pertussis revealed by X-ray diffraction and small-angle X-ray scattering.

Studying the natively unfolded neuronal Tau protein by solution NMR spectroscopy

Tag-Free Semi-Synthesis of the Tau Protein.

Tau pathology modulates Pin1 post-translational modifications and may be relevant as biomarker

The O-β-linked N-acetylglucosaminylation of the Lamin B receptor and its impact on DNA binding and phosphorylation

The Peptidyl–Prolyl Isomerase and Chaperone Par27 of Bordetella pertussis as the Prototype for a New Group of Parvulins

The Study of Posttranslational Modifications of Tau Protein by Nuclear Magnetic Resonance Spectroscopy: Phosphorylation of Tau Protein by ERK2 Recombinant Kinase and Rat Brain Extract, and Acetylation by Recombinant Creb-Binding Protein

The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention?

The peptidyl prolyl cis/trans-isomerase Pin1 recognizes the phospho-Thr212-Pro213 site on Tau.

The thymine-DNA glycosylase regulatory domain: residual structure and DNA binding

Traceless purification and desulfurization of tau protein ligation products

Unraveling a phosphorylation event in a folded protein by NMR spectroscopy: phosphorylation of the Pin1 WW domain by PKA.