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List of works by Stefano Rusconi

96-week results of a dual therapy with darunavir/ritonavir plus rilpivirine once a day vs triple therapy in patients with suppressed viraemia: virological success and non-HIV related morbidity evaluation

scientific article published on 01 February 2020

A Comprehensive Development Agenda on Tenofovir Alafenamide in Clinical Practice

article

A dual regimen of ritonavir/darunavir plus dolutegravir for rescue or simplification of rescue therapy: 48 weeks' observational data.

scientific article published on 30 September 2017

A first update on mapping the human genetic architecture of COVID-19

scientific article published on 3 August 2022

A genotypic analysis of patients receiving Zidovudine with either Lamivudine, Didanosine or Zalcitabine dual therapy using the LiPA point mutation assay to detect genotypic variation at codons 41, 69, 70, 74, 184 and 215

scientific article published on 01 December 2000

A novel methodology for large-scale phylogeny partition

scientific article published on 24 May 2011

A prospective randomized trial on abacavir/lamivudine plus darunavir/ritonavir or raltegravir in HIV-positive drug-naïve patients with CD4<200 cells/uL (the PRADAR study)

scientific article published on 27 September 2019

A push for 90-90-90: Initial treatment with INSTI-based regimens against HIV-1 infection

scientific article published on 20 July 2019

Abacavir Hypersensitivity Reaction after Switching from the Twice-Daily to the Once-Daily Formulation

scholarly article by Cristina Gervasoni et al published January 2007 in AIDS Patient Care and STDs

Absence of new thymidine-associated mutations and evidence of an immune virologic response over a 12-month period in a cohort of antiretroviral-experienced HIV-1-infected subjects treated with tenofovir combination therapy

scientific article published in October 2005

Altered Signaling Lymphocytic Activation Molecule (SLAM) Expression in HIV Infection and Redirection of HIV-Specific Responses via SLAM Triggering

article

Aminooxypentane-RANTES, an inhibitor of R5 human immunodeficiency virus type 1, increases the interferon gamma to interleukin 10 ratio without impairing cellular proliferation

scientific article

An update in the development of HIV entry inhibitors

scientific article published on January 2007

Analysis of protease inhibitor combinations in vitro: activity of lopinavir, amprenavir and tipranavir against HIV type 1 wild-type and drug-resistant isolates

scientific article published on 12 February 2004

Analysis of the env V3 sequences obtained from patients with HIV type 1 infection treated with the immune modulant agent tucaresol.

scientific article published on September 2005

Atazanavir/ritonavir monotherapy as maintenance strategy in HIV-1 treated subjects with viral suppression: 96-week analysis results of the MODAT study

scientific article

Atazanavir/ritonavir monotherapy: 96 week efficacy, safety and bone mineral density from the MODAt randomized trial

scientific article published on 5 March 2016

CD4 cell counts at the third month of HAART may predict clinical failure.

scientific article published on September 1999

COVID-19: studying the global pandemic – foreword

scientific article published in 2020

Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with phosphates, carbamoyl phosphate, and the phosphonate antiviral drug foscarnet

scientific article published in December 2004

Cardiovascular adverse events during treatment with darunavir-based regimens in an Italian observational study

scientific article published on 14 May 2019

Cardiovascular risk and dyslipidemia among persons living with HIV: a review

scientific article published on 9 August 2017

Clinical and epidemiological features of HIV/AIDS infection among migrants at first access to healthcare services as compared to Italian patients in Italy: a retrospective multicentre study, 2000-2010.

scientific article

Clinical and genetic determinants of nevirapine plasma trough concentration.

scientific article published on 5 June 2018

Clinical and genetic factors associated with increased risk of severe liver toxicity in a monocentric cohort of HIV positive patients receiving nevirapine-based antiretroviral therapy

article

Clinical and genetic factors associated with kidney tubular dysfunction in a real-life single centre cohort of HIV-positive patients

scientific article

Clinical impact of anti retroviral resistance testing: current problems and future directions

scientific article

Clinical pharmacology in HIV cure research - what impact have we seen?

scientific article published on 02 January 2019

Clinical validation and applicability of different tipranavir/ritonavir genotypic scores in HIV-1 protease inhibitor-experienced patients

scientific article published in July 2009

Cohort profile: The Observational cohort for the study of DOlutegravir in Antiretroviral Combination REgimens (ODOACRE)

scientific article published on 02 December 2019

Combination of CCR5 and CXCR4 inhibitors in therapy of human immunodeficiency virus type 1 infection: in vitro studies of mixed virus infections.

scientific article published on October 2000

Combined tipranavir and enfuvirtide use associated with higher plasma tipranavir concentrations but not with increased hepatotoxicity: sub-analysis from RESIST

article

Comparative evaluation of seven resistance interpretation algorithms and their derived genotypic inhibitory quotients for the prediction of 48 week virological response to darunavir-based salvage regimens

scientific article published on 29 October 2010

Correlation between inner retinal layer thickness and cognitive function in HIV: new insights from an exploratory study

scientific article

Declining Incidence of AIDS and Increasing Prevalence of AIDS Presenters Among AIDS Patients in Italy ⬇️

scientific article published on October 21, 2003

Description of a "trans-Saharan" strain of human T-lymphotropic virus type 1 in West Africa

scientific article published on March 2008

Determinants of HIV-1 genotypic resistance to darunavir (TMC114) in a large Italian resistance database (Antiretroviral Resistance Cohort Analysis).

scientific article

Differential disappearance of inhibitory natural killer cell receptors during HAART and possible impairment of HIV-1-specific CD8 cytotoxic T lymphocytes.

scientific article published in May 2001

Discontinuation of treatment and adverse events in an Italian cohort of patients on dolutegravir

scientific article published on January 2017

Does GSS still maintain relevance on HAART outcome after the introduction of newest active antiretroviral drugs? 48 weeks results.

scientific article published in December 2011

Dolutegravir (DTG)-containing regimens after receiving raltegravir (RAL) or elvitegravir (EVG): Durability and virological response in a large Italian HIV drug resistance network (ARCA)

article

Dolutegravir Plus Rilpivirine as a Switch Option in cART-Experienced Patients: 96-Week Data

scientific article

Durability of INI-containing regimens after switching from PI-containing regimens: a single-centre cohort of drug-experienced HIV-infected subjects

scientific article published on 09 July 2019

Durability of Second Antiretroviral Regimens in the Italian Cohort Naive Antiretrovirals Foundation Study and Factors Associated with Discontinuation.

scientific article published in December 2017

Early administration of lopinavir/ritonavir plus hydroxychloroquine does not alter the clinical course of SARS-CoV-2 infection: a retrospective cohort study

scientific article published on 10 August 2020

Effect of Legal Status on the Early Treatment Outcomes of Migrants Beginning Combined Antiretroviral Therapy at an Outpatient Clinic in Milan, Italy

scientific article published on 7 April 2017

Effective inhibition of HIV-1 isolated from patients with acute primary HIV-1 infection by aminooxypentane-RANTES

article

Effectiveness of dolutegravir-based regimens as either first-line or switch antiretroviral therapy: data from the Icona cohort

Effectiveness, durability, and safety of darunavir/ritonavir in HIV-1-infected patients in routine clinical practice in Italy: a postauthorization noninterventional study

scientific article published on 6 May 2016

Efficacy and resistance of recently developed non-nucleoside reverse transcriptase inhibitors for HIV-1

article

Efficacy and safety of a dual boosted protease inhibitor-based regimen, atazanavir and fosamprenavir/ritonavir, against HIV: experience in a pediatric population

scientific article

Efficacy and safety of a switch to unboosted atazanavir in combination with nucleoside analogues in HIV-1-infected patients with virological suppression under antiretroviral therapy

article

Efficacy and safety of switching to dolutegravir plus emtricitabine/tenofovir disoproxil fumarate (TDF) or elvitegravir/cobicistat/emtricitabine/TDF in virologically suppressed HIV-infected patients in clinical practice: results from a multicentre, o

article

Efficacy and tolerability of dolutegravir and two nucleos(t)ide reverse transcriptase inhibitors in HIV-1-positive, virologically suppressed patients

scientific article

Efficacy and tolerability of lamivudine plus dolutegravir as a switch strategy in a multicentre cohort of patients with suppressed HIV-1 replication.

scientific article

Efficacy and tolerability of multiple drug therapy in HIV-infected children

scientific article

Efficacy and tolerability of switching to a dual therapy with darunavir/ritonavir plus raltegravir in HIV-infected patients with HIV-1 RNA ≤50 cp/mL.

scientific article published on 5 May 2017

Efficacy, safety and pharmacokinetics of atazanavir (200mg twice daily) plus raltegravir (400mg twice daily) dual regimen in the clinical setting

scientific article published on December 2016

Enhancing care for people living with HIV: current and future monitoring approaches

scientific article published on 15 October 2020

Entry and fusion inhibitors of HIV

article

Evaluation of HIV Transmission Clusters among Natives and Foreigners Living in Italy

scientific article published on 23 July 2020

Evolution of the HIV-1 protease region in heavily pretreated HIV-1 infected patients receiving Atazanavir

scientific article published on 19 November 2007

Factors associated with virological success with raltegravir-containing regimens and prevalence of raltegravir-resistance-associated mutations at failure in the ARCA database.

scientific article published on 4 January 2013

Factors involved in continuance of atazanavir-based regimens: Results from a cohort of HIV1-positive patients

scientific article

Failure to eradicate HIV despite fully successful HAART initiated in the first days of life

article

Favorable therapeutic response with an antiretroviral salvage regimen in an HIV-1-positive subject infected with a CRF11-cpx virus

scientific article published on 31 December 2013

Genomic characterization and phylogenetic analysis of SARS-COV-2 in Italy

scientific article published on 29 March 2020

Genotypic determination of HIV tropism in a cohort of patients perinatally infected with HIV-1 and exposed to antiretroviral therapy

scientific article

HIV and COVID-19 pandemic collision: turning challenges into opportunity

scientific article published in 2021

HIV-1 protease inhibitors in development

scientific article

Human cytomegalovirus double resistance in a donor-positive/recipient-negative lung transplant patient with an impaired CD4-mediated specific immune response.

scientific article

Immunological nonresponse to antiretroviral drugs in HIV infection

article

Immunovirological outcomes in 70 HIV-1-infected patients who switched to lopinavir/ritonavir after failing at least one protease inhibitor-containing regimen: a retrospective cohort study

scientific article

Impact of circulating resistance-associated mutations on HIV pre-exposure prophylaxis (PrEP) efficacy: Modeling from antiretroviral resistance cohort analysis (ARCA) national database

scientific article

Impact of genotypic susceptibility score on cART outcomes during primary HIV infection

scientific article published on 27 June 2019

In vitro evolution of the human immunodeficiency virus type 1 gag-protease region and maintenance of reverse transcriptase resistance following prolonged drug exposure

scientific article published on March 2001

Increased risk of virologic failure to the first antiretroviral regimen in HIV-infected migrants compared to natives: data from the ICONA cohort

scientific article

Inhibition of human immunodeficiency virus type 1 replication in cytokine-stimulated monocytes/macrophages by combination therapy

scientific article published on December 1994

Inhibitors of HIV-1 protease: 10 years after

article

Inhibitors of HIV-1 protease: current state of the art 10 years after their introduction. From antiretroviral drugs to antifungal, antibacterial and antitumor agents based on aspartic protease inhibitors

scientific article published on January 2007

Investigators involvement in the care of HIV-infected individuals: the experience in recent clinical trials

scientific article published in December 2011

Is the rate of virological failure to cART continuing to decline in recent calendar years?

scientific article published on 03 May 2019

Italian consensus statement on management of HIV-infected individuals with advanced disease naïve to antiretroviral therapy.

scientific article published on 28 May 2009

Long-term data on the efficacy and tolerability of lamivudine plus dolutegravir as a switch strategy in a multi-centre cohort of HIV-1-infected, virologically suppressed patients

scientific article published on 12 September 2019

Low expression of inhibitory natural killer receptors in CD8 cytotoxic T lymphocytes in long-term non-progressor HIV-1-infected patients

article

Low frequency of skin reactions in a cohort of patients on raltegravir.

scientific article published on 22 March 2012

Maraviroc as intensification strategy in HIV-1 positive patients with deficient immunological response: an Italian randomized clinical trial

scientific article

New HIV protease inhibitors for drug-resistant viruses

article

New advances in HIV entry inhibitors development

scientific article

New macrocyclic amines showing activity as HIV entry inhibitors against wild type and multi-drug resistant viruses

scientific article published on 22 May 2009

Patterns of in vitro anti-human immunodeficiency virus type 1 antibody production in long-term nonprogressors

scientific article published in December 1997

Phosph(on)ate as a zinc-binding group in metalloenzyme inhibitors: X-ray crystal structure of the antiviral drug foscarnet complexed to human carbonic anhydrase I

scientific article

Pre-ART HIV-1 DNA in CD4+ T cells correlates with baseline viro-immunological status and outcome in patients under first-line ART

article

Predictive role of the three-month CD4 cell count in the long-term clinical outcome of the first HAART regimen

scientific article published on February 2001

Prevalence and risk determinants of HIV-1 and HIV-2 infections in pregnant women in Bissau

article

Prevalence of etravirine (ETR)-RAMs at NNRTI failure and predictors of resistance to ETR in a large Italian resistance database (ARCA).

scientific article published on 26 April 2013

Prevalence of mutations and determinants of genotypic resistance to etravirine (TMC125) in a large Italian resistance database (ARCA).

scientific article published on 8 March 2010

Processivity and drug-dependence of HIV-1 protease

article

Projections of non-communicable disease and health care costs among HIV-positive persons in Italy and the U.S.A.: A modelling study

scientific article published on 23 October 2017

Proportion and factors associated with recent HIV infection in a cohort of patients seen for care in Italy over 1996-2014: Data from the ICONA Foundation Study cohort

scientific article published on 5 December 2017

Quantitative evaluation of the recombinant HIV-1 phenotype to protease inhibitors by a single-step strategy.

scientific article published in June 2000

Relapse of Kaposi's Sarcoma and HHV-8 viremia in an HIV-infected patient switching from protease inhibitor to integrase inhibitor-based antiretroviral therapy

scientific article published on 2 December 2015

Research news in clinical context

scientific article published on 01 December 2020

Response to First-Line Ritonavir-Boosted Protease Inhibitors (PI/r)-Based Regimens in HIV Positive Patients Presenting to Care with Low CD4 Counts: Data from the Icona Foundation Cohort

scientific article

Response to antiretroviral therapy in a patient with an uncommon codon 69 insertion in the human immunodeficiency virus type 1 reverse transcriptase

scientific article published on June 2000

Reversible diabetes in patient with AIDS-related Kaposi's sarcoma treated with interferon α-2a

scientific article published in The Lancet

Rilpivirine resistance and the dangerous liaisons with substitutions at position 184 among patients infected with HIV-1: analysis from a national drug-resistance database (ARCA).

scientific article published on 17 May 2014

Rules-based HIV-1 genotypic resistance interpretation systems predict 8 week and 24 week virological antiretroviral treatment outcome and benefit from drug potency weighting

article

Safety and tolerability of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Disoproxil fumarate in a real life setting: Data from surveillance cohort long-term toxicity antiretrovirals/antivirals (SCOLTA) project.

scientific article

Safety of statin therapy in HIV/hepatitis C virus-coinfected patients

scientific article published in October 2007

Salvage therapy or simplification of salvage regimens with dolutegravir plus ritonavir-boosted darunavir dual therapy in highly cART-experienced subjects: an Italian cohort.

scientific article

Self-reported olfactory and taste disorders in SARS-CoV-2 patients: a cross-sectional study

scientific article published on 26 March 2020

Serious heart involvement with central nervous system impairment in bilateral pnemonia due to Mycoplasma pneumoniae

Serum 2′-5′-Oligoadenylate Synthetase Levels and Clinical Response to Interferon-β Therapy in Women with Genital Human Papillomavirus Infection

scientific article published on 01 May 1994

Simplification to atazanavir/ritonavir monotherapy for HIV-1 treated individuals on virological suppression: 48-week efficacy and safety results

scientific article

Successful pharmacogenetics-based optimization of unboosted atazanavir plasma exposure in HIV-positive patients: a randomized, controlled, pilot study (the REYAGEN study).

scientific article published on 14 July 2015

Successful rescue therapy with Raltegravir (MK-0518) and Etravirine (TMC125) in an hiv-infected patient failing all four classes of antiretroviral drugs

scientific article published in May 2008

Survival in HIV-infected patients with lymphoma according to the choice of antiretroviral treatment: an observational multicentre study

article

Susceptibility to PNU-140690 (Tipranavir) of human immunodeficiency virus type 1 isolates derived from patients with multidrug resistance to other protease inhibitors

scientific article published on May 2000

Switch to maraviroc with darunavir/r, both QD, in patients with suppressed HIV-1 was well tolerated but virologically inferior to standard antiretroviral therapy: 48-week results of a randomized trial.

scientific article published on 21 November 2017

Switching to dual/monotherapy determines an increase in CD8+ in HIV-infected individuals: an observational cohort study.

scientific article

Symmetric ambulatory arterial stiffness index and 24-h pulse pressure in HIV infection: results of a nationwide cross-sectional study

scientific article published in March 2013

The Less Drugs Regimens (LDRs) therapy approach in HIV-1: an Italian expert panel perspective for the long-term management of HIV-1 infection

scientific article published on June 30, 2012

The crosstalk between antiretrovirals pharmacology and HIV drug resistance

scientific article published on 14 June 2020

The feature of Metabolic Syndrome in HIV naive patients is not the same of those treated: Results from a prospective study

article

The problem of renal function monitoring in patients treated with the novel antiretroviral drugs

scientific article published on May 2014

The role of baseline HIV-1 RNA, drug resistance, and regimen type as determinants of response to first-line antiretroviral therapy

scientific article published on 11 July 2014

Therapeutic immunization with HIV-1 Tat reduces immune activation and loss of regulatory T-cells and improves immune function in subjects on HAART

scientific article

Tipranavir in the protease inhibitors arena

scientific article published on December 2011

Tipranavir: a novel protease inhibitor for HIV therapy

article

Treatment response to ritonavir-boosted tipranavir versus ritonavir-boosted lopinavir in HIV-1 patients with higher lopinavir mutation scores

scientific article

Treatment simplification to atazanavir/ritonavir + lamivudine versus maintenance of atazanavir/ritonavir + two NRTIs in virologically suppressed HIV-1-infected patients: 48 week results from a randomized trial (ATLAS-M).

scientific article

Triglyceride/HDL ratio and its impact on the risk of diabetes mellitus development during ART.

scientific article published on 5 June 2016

Unusual codon 69 insertions: influence on human immunodeficiency virus type 1 reverse transcriptase drug susceptibility

scientific article published in January 2004

Update on the development of HIV entry inhibitors

article

Use of multiplex PCR assay and DNA fingerprinting analysis for typing of multidrug-resistant Mycobacterium tuberculosis strains

scientific article published on 01 November 1997

Use of quantitative ultrasound as bone mineral density evaluation in an Italian female population living with HIV: A real-life experience

scientific article published on 25 January 2018

Vpr and HIV-1 disease progression: R77Q mutation is associated with long-term control of HIV-1 infection in different groups of patients

scientific article

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