List of works by Bernard Lopez

53BP1 Protects against CtIP-Dependent Capture of Ectopic Chromosomal Sequences at the Junction of Distant Double-Strand Breaks

scientific article

A homologous recombination defect affects replication-fork progression in mammalian cells.

scientific article published on 18 December 2007

A nonsense mutation in the DNA repair factor Hebo causes mild bone marrow failure and microcephaly.

scientific article

A role for BLM in double-strand break repair pathway choice: prevention of CtIP/Mre11-mediated alternative nonhomologous end-joining.

scientific article published on 3 October 2013

A threshold of endogenous stress is required to engage cellular response to protect against mutagenesis.

scientific article published on 11 July 2016

AKT1 represses gene conversion induced by different genotoxic stresses and induces supernumerary centrosomes and aneuploidy in hamster ovary cells.

scientific article published on 27 April 2009

Alpha-thalassemia haplotypes in the Algerian population

scientific article published on March 1987

An in vitro enzymatic assay coupled to proteomics analysis reveals a new DNA processing activity for Ewing sarcoma and TAF(II)68 proteins.

scientific article published on November 2006

An xrcc4 defect or Wortmannin stimulates homologous recombination specifically induced by double-strand breaks in mammalian cells.

scientific article published on August 2002

Analysis of intrachromosomal homologous recombination in mammalian cell, using tandem repeat sequences.

scientific article

Bax and Bid, two proapoptotic Bcl-2 family members, inhibit homologous recombination, independently of apoptosis regulation.

scientific article published in May 2006

Bcl-2 inhibits nuclear homologous recombination by localizing BRCA1 to the endomembranes

scientific article

Cellular uptake pathways of sepiolite nanofibers and DNA transfection improvement.

scientific article

Characterization of homologous recombination induced by replication inhibition in mammalian cells

scientific article

Characterization of mammalian RAD51 double strand break repair using non-lethal dominant-negative forms.

scientific article

Characterization of two nuclear mammalian homologous DNA-pairing activities that do not require associated exonuclease activity.

scientific article

Chromosome translocation based on illegitimate recombination in human tumors

scientific article

Chronic exposure to sublethal doses of radiation mimetic Zeocin selects for clones deficient in homologous recombination.

scientific article published on 15 December 2006

Control of alternative end joining by the chromatin remodeler p400 ATPase.

scientific article

CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair.

scientific article published on 19 March 2018

DNA double-strand break repair signalling: the case of RAD51 post-translational regulation.

scientific article

Directional recombination is initiated at a double strand break in human nuclear extracts ⬇️

scientific article published on February 11, 1992

Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers.

scientific article

Genetic interactions between RAD51 and its paralogues for centrosome fragmentation and ploidy control, independently of the sensitivity to genotoxic stresses

scientific article

Genomic rearrangements induced by unscheduled DNA double strand breaks in somatic mammalian cells.

scientific article published on 28 February 2017

Homologous pairing between single-stranded DNA immobilized on a nitrocellulose membrane and duplex DNA is specific for RecA activity in bacterial crude extract

scientific article published on August 1993

Homologous recombination induced by replication inhibition, is stimulated by expression of mutant p53.

scientific article published on January 2002

Homologous recombination is involved in the repair response of mammalian cells to low doses of tritium.

scientific article published in August 2008

Impact of the KU80 pathway on NHEJ-induced genome rearrangements in mammalian cells.

scientific article

Improving gene replacement by intracellular formation of linear homologous DNA.

scientific article published on May 2005

Inactivation of the RAD51 recombination pathway stimulates UV-induced mutagenesis in mammalian cells

scientific article published on 01 June 2002

Increase of spontaneous intrachromosomal homologous recombination in mammalian cells expressing a mutant p53 protein

scientific article published on March 1997

Involvement of DNA polymerase mu in the repair of a specific subset of DNA double-strand breaks in mammalian cells.

scientific article published on 5 May 2007

Is homologous recombination really an error-free process?

scientific article

Is non-homologous end-joining really an inherently error-prone process?

scientific article published on 16 January 2014

Molecular analysis of homologous recombination catalysed by human nuclear extract: fidelity and DNase protection

scientific article published in January 1989

Mutant p53 proteins stimulate spontaneous and radiation-induced intrachromosomal homologous recombination independently of the alteration of the transactivation activity and of the G1 checkpoint.

scientific article published on June 1999

Overexpression of mammalian Rad51 does not stimulate tumorigenesis while a dominant-negative Rad51 affects centrosome fragmentation, ploidy and stimulates tumorigenesis, in p53-defective CHO cells.

scientific article published in October 2003

PARP2 controls double-strand break repair pathway choice by limiting 53BP1 accumulation at DNA damage sites and promoting end-resection

scientific article published on 3 October 2017

PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways.

scientific article

Phospho-Ku70 induced by DNA damage interacts with RNA Pol II and promotes the formation of phospho-53BP1 foci to ensure optimal cNHEJ

scientific article published on 01 November 2021

Physical interactions between DNA and sepiolite nanofibers, and potential application for DNA transfer into mammalian cells

scientific article

Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1.

scientific article

Replication Stress, DNA Damage, Inflammatory Cytokines and Innate Immune Response

scientific article published on 09 April 2020

Replication stress in Mammalian cells and its consequences for mitosis

scientific article

RhoB promotes γH2AX dephosphorylation and DNA double-strand break repair

scientific article

Role of RAD51 in sister-chromatid exchanges in mammalian cells.

scientific article published in October 2001

Role of the double-strand break repair pathway in the maintenance of genomic stability.

scientific article published on 30 October 2014

S-phase progression stimulates both the mutagenic KU-independent pathway and mutagenic processing of KU-dependent intermediates, for nonhomologous end joining

scientific article published on 24 September 2007

Sepiolite as a New Nanocarrier for DNA Transfer into Mammalian Cells: Proof of Concept, Issues and Perspectives

scientific article published on 29 December 2017

Signaling from Mus81-Eme2-Dependent DNA Damage Elicited by Chk1 Deficiency Modulates Replication Fork Speed and Origin Usage.

scientific article published on 19 January 2016

Slow Replication Fork Velocity of Homologous Recombination-Defective Cells Results from Endogenous Oxidative Stress

scientific article

Spontaneous slow replication fork progression elicits mitosis alterations in homologous recombination-deficient mammalian cells.

scientific article

Structural effect of donor DNA on the initiation of recombination for double strand break repair in human nuclear extracts ⬇️

scientific article published on October 11, 1992

Targeted gene correction with 5' acridine-oligonucleotide conjugates.

scientific article published on January 2007

Terminal deoxynucleotidyl transferase requires KU80 and XRCC4 to promote N-addition at non-V(D)J chromosomal breaks in non-lymphoid cells

scientific article

The Cohesin Complex Prevents the End Joining of Distant DNA Double-Strand Ends.

scientific article published on 10 December 2015

The DNA polymerase lambda is required for the repair of non-compatible DNA double strand breaks by NHEJ in mammalian cells

scientific article published on 31 May 2006

The causes of replication stress and their consequences on genome stability and cell fate.

scientific article

The cohesin complex prevents the end-joining of distant DNA double-strand ends in S phase: Consequences on genome stability maintenance

scientific article published on 21 June 2016

The helicase FBH1 is tightly regulated by PCNA via CRL4(Cdt2)-mediated proteolysis in human cells

scientific article

The nucleoporin 153, a novel factor in double-strand break repair and DNA damage response.

scientific article published on 16 January 2012

Yeast cells reveal the misfolding and the cellular mislocalization of the human BRCA1 protein.

scientific article published on 17 October 2016

[Direct role of p53 on homologous recombination]

scientific article published on 01 January 2005

[Double strand break repair, one mechanism can hide another: alternative non-homologous end joining]

scientific article published on 06 July 2011

p53's double life: transactivation-independent repression of homologous recombination.

scientific article published on June 2004

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