List of works - Anne Barlier

18F-FDG avidity of pheochromocytomas and paragangliomas: a new molecular imaging signature?

scientific article published on 16 April 2009

A Familial Form of Congenital Hypopituitarism Due to aPROP1Mutation in a Large Kindred: Phenotypic andin VitroFunctional Studies

scientific article published on 01 November 2004

A MEN1 syndrome with a paraganglioma.

scientific article published on 19 June 2013

A Neonatal Form of Isolated ACTH Deficiency Frequently Associated with Tpit Gene Mutations

article

A Novel Dysfunctional LHX4 Mutation with High Phenotypical Variability in Patients with Hypopituitarism

scientific article published on 29 April 2008

A genome-wide approach reveals novel imprinted genes expressed in the human placenta

scientific article published on 16 August 2012

A new mutation of the gene encoding the transcription factor Pit-1 is responsible for combined pituitary hormone deficiency

scientific article published in August 1996

A new specific succinate-glutamate metabolomic hallmark in SDHx-related paragangliomas

scientific article

A potential inhibitory role for the new truncated variant of somatostatin receptor 5, sst5TMD4, in pituitary adenomas poorly responsive to somatostatin analogs

scientific article published on 16 March 2010

Absence of IDH mutation identifies a novel radiologic and molecular subtype of WHO grade II gliomas with dismal prognosis

scientific article

An Uncommon Phenotype with Familial Central Hypogonadism Caused by a NovelPROP1Gene Mutant Truncated in the Transactivation Domain

article

Aryl hydrocarbon receptor-interacting protein gene mutations in familial isolated pituitary adenomas: analysis in 73 families.

scientific article published on 23 January 2007

Case Report of GNAS Epigenetic Defect Revealed by a Congenital Hypothyroidism

scientific article published on 01 April 2015

Case seminar: a young female with acute hyponatremia and a sellar mass

scientific article published on 24 August 2011

Cervical paragangliomas: is SDH genetic analysis systematically required?

scientific article published on 7 November 2007

Clinical and genetic characterization of pituitary gigantism: an international collaborative study in 208 patients.

scientific article published on 17 July 2015

Clinical characteristics and therapeutic responses in patients with germ-line AIP mutations and pituitary adenomas: an international collaborative study

scientific article published on 4 August 2010

Combined pituitary hormone deficiency: current and future status

scientific article

Combined treatment by octreotide and everolimus: Octreotide enhances inhibitory effect of everolimus in aggressive meningiomas

scientific article published on 27 May 2015

Combining Cadherin Expression with Molecular Markers Discriminates Invasiveness in Growth Hormone and Prolactin Pituitary Adenomas.

scientific article published on 20 December 2015

Comparison of [111In]pentetreotide-SPECT and [18F]FDOPA-PET in the localization of extra-adrenal paragangliomas: the case for a patient-tailored use of nuclear imaging modalities

scientific article published on 01 January 2011

Conditional overexpression of the wild-type Gs alpha as the gsp oncogene initiates chronic extracellularly regulated kinase 1/2 activation and hormone hypersecretion in pituitary cell lines

scientific journal article

Congenital Isolated Adrenocorticotropin Deficiency: An Underestimated Cause of Neonatal Death, Explained byTPITGene Mutations

scientific article published on 21 December 2004

Congenital pituitary hormone deficiencies: role ofLHX3/LHX4genes

article

Deficit in anterior pituitary function and variable immune deficiency (DAVID) in children presenting with adrenocorticotropin deficiency and severe infections.

scientific article published on 19 October 2011

Demonstration of enhanced potency of a chimeric somatostatin-dopamine molecule, BIM-23A387, in suppressing growth hormone and prolactin secretion from human pituitary somatotroph adenoma cells.

scientific article published in December 2002

Detection of genetic hypopituitarism in an adult population of idiopathic pituitary insufficiency patients with growth hormone deficiency.

scientific article published in September 2011

Dose-dependent dual role of PIT-1 (POU1F1) in somatolactotroph cell proliferation and apoptosis

scientific article

Déficit hypophysaire combiné multiple : aspects cliniques et génétiques

scientific article published on 01 February 2008

European guidance for the molecular diagnosis of pseudohypoparathyroidism not caused by point genetic variants at GNAS: an EQA study

scientific article

European guidance for the molecular diagnosis of pseudohypoparathyroidism not caused by point genetic variants at GNAS: an EQA study

article published in 2015

Everolimus and Octreotide for Patients with Recurrent Meningioma: Results from the Phase II CEVOREM Trial

scientific article published on 22 January 2020

Expression of aryl hydrocarbon receptor (AHR) and AHR-interacting protein in pituitary adenomas: pathological and clinical implications.

scientific article published on 25 June 2009

Expression of functional growth hormone secretagogue receptors in human pituitary adenomas: polymerase chain reaction, triple in-situ hybridization and cell culture studies.

scientific article published in July 1999

Expression of somatostatin receptors, dopamine D₂ receptors, noradrenaline transporters, and vesicular monoamine transporters in 52 pheochromocytomas and paragangliomas.

scientific article

First report of bilateral pheochromocytoma in the clinical spectrum of HIF2A-related polycythemia-paraganglioma syndrome.

scientific article published on 28 March 2013

First report of harlequin syndrome as the presenting feature of Carney Triad: a diagnostic and imaging challenge

scientific article published on 11 June 2012

Frequent Large GermlineHRPT2Deletions in a French National Cohort of Patients With Primary Hyperparathyroidism

article

Functional characterization of nonmetastatic paraganglioma and pheochromocytoma by 18F‐FDOPA PET: focus on missed lesions ⬇️

scientific article published on May 6, 2013

GHRH excess and blockade in X-LAG syndrome.

scientific article published on 15 December 2015

Genetic analysis in young patients with sporadic pituitary macroadenomas: besides AIP don't forget MEN1 genetic analysis.

scientific article

Genetic causes of combined pituitary hormone deficiencies in humans ⬇️

scientific article published on April 21, 2012

Genetic screening of combined pituitary hormone deficiency: experience in 195 patients

scientific article published on 30 May 2006

Ghrelin receptor (GHS-R1a) and its constitutive activity in somatotroph adenomas: a new co-targeting therapy using GHS-R1a inverse agonists and somatostatin analogs.

scientific article published on December 2014

Gigantism and acromegaly due to Xq26 microduplications and GPR101 mutation

scientific article

Gs alpha overexpression and loss of Gs alpha imprinting in human somatotroph adenomas: association with tumor size and response to pharmacologic treatment

scientific article

Heterogeneous genetic background of the association of pheochromocytoma/paraganglioma and pituitary adenoma: results from a large patient cohort

scientific article

Heterozygous LHX3 mutations may lead to a mild phenotype of combined pituitary hormone deficiency

scientific article published on 27 September 2018

High prevalence of AIP gene mutations following focused screening in young patients with sporadic pituitary macroadenomas.

scientific article published on 13 July 2011

Higher risk of death among MEN1 patients with mutations in the JunD interacting domain: a Groupe d’étude des Tumeurs Endocrines (GTE) cohort study

scientific article published on 31 January 2013

Identifying the Deleterious Effect of Rare LHX4 Allelic Variants, a Challenging Issue

scientific article published on 8 May 2015

In vivo and in vitro evidence of somatostatin receptors expression in a dedifferentiated retroperitoneal liposarcoma

article

Lentiviral vectors efficiently transduce human gonadotroph and somatotroph adenomas in vitro. Targeted expression of transgene by pituitary hormone promoters

scientific article

Lessons from monogenic causes of growth hormone deficiency

scientific article published on 5 May 2017

Long-term control of a MEN1 prolactin secreting pituitary carcinoma after temozolomide treatment

scientific article published on 20 April 2012

Looking beyond the thyroid: advances in the understanding of pheochromocytoma and hyperparathyroidism phenotypes in MEN2 and of non-MEN2 familial forms.

scientific article published on 5 September 2017

MECHANISMS IN ENDOCRINOLOGY: An update in the genetic aetiologies of combined pituitary hormone deficiency

scientific article

McCune-Albright syndrome: a detailed pathological and genetic analysis of disease effects in an adult patient

scientific article published on 25 July 2014

Medical therapies in pituitary adenomas: Current rationale for the use and future perspectives

scientific article

Mutations in theAryl Hydrocarbon Receptor Interacting ProteinGene Are Not Highly Prevalent among Subjects with Sporadic Pituitary Adenomas

article

Mécanismes de tumorigenèse hypophysaire

scientific article published on 19 October 2008

Neuroendocrine tumors: insights into innovative therapeutic options and rational development of targeted therapies.

scientific article published on 27 October 2013

PROKR2 variants in multiple hypopituitarism with pituitary stalk interruption.

scientific article published on 30 March 2012

Pasireotide and octreotide antiproliferative effects and sst2 trafficking in human pancreatic neuroendocrine tumor cultures

article

Phenotypic Homogeneity and Genotypic Variability in a Large Series of Congenital Isolated ACTH-Deficiency Patients withTPITGene Mutations

article

Physiopathology of somatolactotroph cells: from transduction mechanisms to cotargeting therapy.

scientific article published on March 2011

Pit-1 gene expression in human lactotroph and somatotroph pituitary adenomas is correlated to D2 receptor gene expression

scientific article published in September 1996

Pit-1 gene expression in the human pituitary and pituitary adenomas

scientific article published in July 1994

Pituitary hormone deficiencies due to transcription factor gene alterations.

scientific article

Pituitary stalk interruption syndrome in 83 patients: novel HESX1 mutation and severe hormonal prognosis in malformative forms.

scientific article

Preoperative 18F-FDG Uptake is Strongly Correlated with Malignancy, Weiss Score, and Molecular Markers of Aggressiveness in Adrenal Cortical Tumors

scientific article published on 01 June 2012

Primary hyperparathyroidism as first manifestation in MEN 2A: an international multicenter study

scientific article published on 01 May 2020

Pronostic and therapeutic consequences of Gs alpha mutations in somatotroph adenomas

scientific article published on May 1998

Prospective comparison of (68)Ga-DOTATATE and (18)F-FDOPA PET/CT in patients with various pheochromocytomas and paragangliomas with emphasis on sporadic cases

scientific article published on 5 December 2015

Quelles causes génétiques rechercher en présence d’un déficit en hormone de croissance ?

scientific article published on 15 April 2011

RET gene mutations are not involved in the origin of human testicular seminoma

scientific article

Relevance of coexpression of somatostatin and dopamine D2 receptors in pituitary adenomas.

scientific article published on 23 December 2007

Should routine analysis of the MEN1 gene be performed in all patients with primary hyperparathyroidism under 40 years of age?

scientific article published on June 2010

Signalling pathway alterations in pituitary adenomas: involvement of Gsalpha, cAMP and mitogen-activated protein kinases.

scientific article published on September 2009

Simultaneous hyper- and hypomethylation at imprinted loci in a subset of patients with GNAS epimutations underlies a complex and different mechanism of multilocus methylation defect in pseudohypoparathyroidism type 1b.

scientific article published on 28 May 2013

Sinonasal paraganglioma with long-delayed recurrence and metastases: genetic and imaging findings

scientific article

Somatic gain-of-function HIF2A mutations in sporadic central nervous system hemangioblastomas

scientific article published on 29 October 2015

Somatostatin analogues increase AIP expression in somatotropinomas, irrespective of Gsp mutations.

scientific article published on 16 September 2013

Somatostatin receptor sst2 decreases cell viability and hormonal hypersecretion and reverses octreotide resistance of human pituitary adenomas

scientific article published on December 2008

Somatostatin receptor sst2 gene transfer in human prolactinomas in vitro: Impact on sensitivity to dopamine, somatostatin and dopastatin, in the control of prolactin secretion

article

Somatostatinergic ligands in dopamine-sensitive and -resistant prolactinomas

scientific article published on May 2008

Targeting Dopamine Receptors Subtype 2 (D2DR) in Pheochromocytomas: Head-to-Head Comparison Between In Vitro and In Vivo Findings

scientific article published on 05 September 2013

The analysis of quantitative expression of somatostatin and dopamine receptors in gastro-entero-pancreatic tumours opens new therapeutic strategies

scientific article published in December 2006

The gsp oncogene disrupts Ras/ERK-dependent prolactin gene regulation in gsp inducible somatotroph cell line.

scientific article published on February 2011

The role of 18F-FDOPA and 18F-FDG-PET in the management of malignant and multifocal phaeochromocytomas

scientific article published on 3 April 2008

The significance of MEN1 mutations in pituitary carcinomas.

scientific article published in August 2013

Une cause de calcifications intracérébrales à connaître : la pseudohypoparathyroïdie de type Ib

scientific article published on 03 August 2008

Unilateral agenesis of internal carotid artery associated with congenital combined pituitary hormone deficiency and pituitary stalk interruption without HESX1, LHX4 or OTX2 mutation: a case report.

scientific article published in December 2012

Unraveling the intrafamilial correlations and heritability of tumor types in MEN1: a Groupe d'étude des Tumeurs Endocrines study

scientific article published on 21 September 2015

Unusual presentation of multiple endocrine neoplasia type 2A in a patient with the C634R mutation of the RET-protooncogene

scientific article published on 26 August 2008

List of works by Anne Barlier

18F-FDG avidity of pheochromocytomas and paragangliomas: a new molecular imaging signature?

A Familial Form of Congenital Hypopituitarism Due to aPROP1Mutation in a Large Kindred: Phenotypic andin VitroFunctional Studies

A MEN1 syndrome with a paraganglioma.

A Neonatal Form of Isolated ACTH Deficiency Frequently Associated with Tpit Gene Mutations

A Novel Dysfunctional LHX4 Mutation with High Phenotypical Variability in Patients with Hypopituitarism

A genome-wide approach reveals novel imprinted genes expressed in the human placenta

A new mutation of the gene encoding the transcription factor Pit-1 is responsible for combined pituitary hormone deficiency

A new specific succinate-glutamate metabolomic hallmark in SDHx-related paragangliomas

A potential inhibitory role for the new truncated variant of somatostatin receptor 5, sst5TMD4, in pituitary adenomas poorly responsive to somatostatin analogs

Absence of IDH mutation identifies a novel radiologic and molecular subtype of WHO grade II gliomas with dismal prognosis

An Uncommon Phenotype with Familial Central Hypogonadism Caused by a NovelPROP1Gene Mutant Truncated in the Transactivation Domain

Aryl hydrocarbon receptor-interacting protein gene mutations in familial isolated pituitary adenomas: analysis in 73 families.

Case Report of GNAS Epigenetic Defect Revealed by a Congenital Hypothyroidism

Case seminar: a young female with acute hyponatremia and a sellar mass

Cervical paragangliomas: is SDH genetic analysis systematically required?

Clinical and genetic characterization of pituitary gigantism: an international collaborative study in 208 patients.

Clinical characteristics and therapeutic responses in patients with germ-line AIP mutations and pituitary adenomas: an international collaborative study

Combined pituitary hormone deficiency: current and future status

Combined treatment by octreotide and everolimus: Octreotide enhances inhibitory effect of everolimus in aggressive meningiomas

Combining Cadherin Expression with Molecular Markers Discriminates Invasiveness in Growth Hormone and Prolactin Pituitary Adenomas.

Comparison of [111In]pentetreotide-SPECT and [18F]FDOPA-PET in the localization of extra-adrenal paragangliomas: the case for a patient-tailored use of nuclear imaging modalities

Conditional overexpression of the wild-type Gs alpha as the gsp oncogene initiates chronic extracellularly regulated kinase 1/2 activation and hormone hypersecretion in pituitary cell lines

Congenital Isolated Adrenocorticotropin Deficiency: An Underestimated Cause of Neonatal Death, Explained byTPITGene Mutations

Congenital pituitary hormone deficiencies: role ofLHX3/LHX4genes

Deficit in anterior pituitary function and variable immune deficiency (DAVID) in children presenting with adrenocorticotropin deficiency and severe infections.

Demonstration of enhanced potency of a chimeric somatostatin-dopamine molecule, BIM-23A387, in suppressing growth hormone and prolactin secretion from human pituitary somatotroph adenoma cells.

Detection of genetic hypopituitarism in an adult population of idiopathic pituitary insufficiency patients with growth hormone deficiency.

Dose-dependent dual role of PIT-1 (POU1F1) in somatolactotroph cell proliferation and apoptosis

Déficit hypophysaire combiné multiple : aspects cliniques et génétiques

European guidance for the molecular diagnosis of pseudohypoparathyroidism not caused by point genetic variants at GNAS: an EQA study

European guidance for the molecular diagnosis of pseudohypoparathyroidism not caused by point genetic variants at GNAS: an EQA study

Everolimus and Octreotide for Patients with Recurrent Meningioma: Results from the Phase II CEVOREM Trial

Expression of aryl hydrocarbon receptor (AHR) and AHR-interacting protein in pituitary adenomas: pathological and clinical implications.

Expression of functional growth hormone secretagogue receptors in human pituitary adenomas: polymerase chain reaction, triple in-situ hybridization and cell culture studies.

Expression of somatostatin receptors, dopamine D₂ receptors, noradrenaline transporters, and vesicular monoamine transporters in 52 pheochromocytomas and paragangliomas.

First report of bilateral pheochromocytoma in the clinical spectrum of HIF2A-related polycythemia-paraganglioma syndrome.

First report of harlequin syndrome as the presenting feature of Carney Triad: a diagnostic and imaging challenge

Frequent Large GermlineHRPT2Deletions in a French National Cohort of Patients With Primary Hyperparathyroidism

Functional characterization of nonmetastatic paraganglioma and pheochromocytoma by 18F‐FDOPA PET: focus on missed lesions ⬇️

GHRH excess and blockade in X-LAG syndrome.

Genetic analysis in young patients with sporadic pituitary macroadenomas: besides AIP don't forget MEN1 genetic analysis.

Genetic causes of combined pituitary hormone deficiencies in humans ⬇️

Genetic screening of combined pituitary hormone deficiency: experience in 195 patients

Ghrelin receptor (GHS-R1a) and its constitutive activity in somatotroph adenomas: a new co-targeting therapy using GHS-R1a inverse agonists and somatostatin analogs.

Gigantism and acromegaly due to Xq26 microduplications and GPR101 mutation

Gs alpha overexpression and loss of Gs alpha imprinting in human somatotroph adenomas: association with tumor size and response to pharmacologic treatment

Heterogeneous genetic background of the association of pheochromocytoma/paraganglioma and pituitary adenoma: results from a large patient cohort

Heterozygous LHX3 mutations may lead to a mild phenotype of combined pituitary hormone deficiency

High prevalence of AIP gene mutations following focused screening in young patients with sporadic pituitary macroadenomas.

Higher risk of death among MEN1 patients with mutations in the JunD interacting domain: a Groupe d’étude des Tumeurs Endocrines (GTE) cohort study

Identifying the Deleterious Effect of Rare LHX4 Allelic Variants, a Challenging Issue

In vivo and in vitro evidence of somatostatin receptors expression in a dedifferentiated retroperitoneal liposarcoma

Lentiviral vectors efficiently transduce human gonadotroph and somatotroph adenomas in vitro. Targeted expression of transgene by pituitary hormone promoters

Lessons from monogenic causes of growth hormone deficiency

Long-term control of a MEN1 prolactin secreting pituitary carcinoma after temozolomide treatment

Looking beyond the thyroid: advances in the understanding of pheochromocytoma and hyperparathyroidism phenotypes in MEN2 and of non-MEN2 familial forms.

MECHANISMS IN ENDOCRINOLOGY: An update in the genetic aetiologies of combined pituitary hormone deficiency

McCune-Albright syndrome: a detailed pathological and genetic analysis of disease effects in an adult patient

Medical therapies in pituitary adenomas: Current rationale for the use and future perspectives

Mutations in theAryl Hydrocarbon Receptor Interacting ProteinGene Are Not Highly Prevalent among Subjects with Sporadic Pituitary Adenomas

Mécanismes de tumorigenèse hypophysaire

Neuroendocrine tumors: insights into innovative therapeutic options and rational development of targeted therapies.

PROKR2 variants in multiple hypopituitarism with pituitary stalk interruption.

Pasireotide and octreotide antiproliferative effects and sst2 trafficking in human pancreatic neuroendocrine tumor cultures

Phenotypic Homogeneity and Genotypic Variability in a Large Series of Congenital Isolated ACTH-Deficiency Patients withTPITGene Mutations

Physiopathology of somatolactotroph cells: from transduction mechanisms to cotargeting therapy.

Pit-1 gene expression in human lactotroph and somatotroph pituitary adenomas is correlated to D2 receptor gene expression

Pit-1 gene expression in the human pituitary and pituitary adenomas

Pituitary hormone deficiencies due to transcription factor gene alterations.

Pituitary stalk interruption syndrome in 83 patients: novel HESX1 mutation and severe hormonal prognosis in malformative forms.

Preoperative 18F-FDG Uptake is Strongly Correlated with Malignancy, Weiss Score, and Molecular Markers of Aggressiveness in Adrenal Cortical Tumors

Primary hyperparathyroidism as first manifestation in MEN 2A: an international multicenter study

Pronostic and therapeutic consequences of Gs alpha mutations in somatotroph adenomas

Prospective comparison of (68)Ga-DOTATATE and (18)F-FDOPA PET/CT in patients with various pheochromocytomas and paragangliomas with emphasis on sporadic cases

Quelles causes génétiques rechercher en présence d’un déficit en hormone de croissance ?

RET gene mutations are not involved in the origin of human testicular seminoma

Relevance of coexpression of somatostatin and dopamine D2 receptors in pituitary adenomas.

Should routine analysis of the MEN1 gene be performed in all patients with primary hyperparathyroidism under 40 years of age?

Signalling pathway alterations in pituitary adenomas: involvement of Gsalpha, cAMP and mitogen-activated protein kinases.