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List of works by Christine Clayton

3' processing in protists

scientific article

A domino effect in drug action: from metabolic assault towards parasite differentiation

scientific article published on 5 November 2010

A doubly inducible system for RNA interference and rapid RNAi plasmid construction in Trypanosoma brucei

scientific article published in January 2005

A genome-wide tethering screen reveals novel potential post-transcriptional regulators in Trypanosoma brucei

scientific article

A plasmid shuttle vector bearing an rRNA promoter is extrachromosomally maintained in Crithidia fasciculata.

scientific article published in July 1996

A possible role for the 3'-untranslated region in developmental regulation in Trypanosoma brucei

scientific article published in September 1993

A potential role for a novel ZC3H5 complex in regulating mRNA translation in Trypanosoma brucei

scientific article published on 05 August 2020

A role for Caf1 in mRNA deadenylation and decay in trypanosomes and human cells

scientific article published on 27 April 2008

A role for the exosome in the in vivo degradation of unstable mRNAs

scientific article

A search for Trypanosoma brucei rhodesiense diagnostic antigens by proteomic screening and targeted cloning

scientific article

An RNAi screen of the RRM-domain proteins of Trypanosoma brucei

scholarly article published by Jörg D Hoheisel in 2009

An essential dimeric membrane protein of trypanosome glycosomes.

scientific article published in March 2001

An unambiguous nomenclature for the major surface glycoproteins of the procyclic form of Trypanosoma brucei.

scientific article published in September 1999

Analysis of stage-specific gene expression in the bloodstream and the procyclic form of Trypanosoma brucei using a genomic DNA-microarray

scientific article

Binding of coatomer by the PEX11 C-terminus is not required for function

scientific article published on 01 November 2000

Chapter 18 Trypanosomes as a Model to Investigate mRNA Decay Pathways

scientific article published on 01 January 2008

Characterisation of the growth and differentiation in vivo and in vitro-of bloodstream-form Trypanosoma brucei strain TREU 927.

scientific article

Characterization and developmentally regulated localization of the mitochondrial carrier protein homologue MCP6 from Trypanosoma brucei

scientific article published on August 2006

Compartmentation of phosphoglycerate kinase in Trypanosoma brucei plays a critical role in parasite energy metabolism ⬇️

scientific article published on September 29, 1998

Composition of the editing complex of Trypanosoma brucei

scientific article

Control and regulation of gene expression: quantitative analysis of the expression of phosphoglycerate kinase in bloodstream form Trypanosoma brucei

scientific article published on 8 November 2007

Control of mRNA degradation in trypanosomes

scientific article published on 01 June 2008

Corrigendum to “Functional analysis of Trypanosoma brucei PUF1” [Mol. Biochem. Parasitol. 150 (2006) 340–349]

scholarly article published in Molecular and Biochemical Parasitology

DRBD1 is the Trypanosoma brucei homologue of the spliceosome-associated protein 49.

scientific article published on 21 March 2009

Depletion of 14-3-3 proteins in bloodstream-form Trypanosoma brucei inhibits variant surface glycoprotein recycling

scientific article

Depletion of GIM5 causes cellular fragility, a decreased glycosome number, and reduced levels of ether-linked phospholipids in trypanosomes.

scientific article published on 26 June 2003

Depletion of the Trypanosome Pumilio domain protein PUF2 or of some other essential proteins causes transcriptome changes related to coding region length

scientific article

Depletion of trypanosome CTR9 leads to gene expression defects

scientific article

Effect of multiple downstream splice sites on polyadenylation in Trypanosoma brucei

scientific article published on 01 May 1998

Effects of depletion and overexpression of the Trypanosoma brucei ribonuclease L inhibitor homologue

scientific article published in January 2004

Elongation and clustering of glycosomes in Trypanosoma brucei overexpressing the glycosomal Pex11p

scientific article published on July 1998

Examination of the mode of action of the almiramide family of natural products against the kinetoplastid parasite Trypanosoma brucei

scientific article

Expression of the RNA recognition motif protein RBP10 promotes a bloodstream-form transcript pattern in Trypanosoma brucei

scientific article

Expression of the RNA-binding protein RBP10 promotes the bloodstream-form differentiation state in Trypanosoma brucei.

scientific article published on 11 August 2017

Factors that bind to RNA polymerase I promoter sequences of Trypanosoma brucei

scientific article published on May 1994

Functional analysis of Trypanosoma brucei PUF1

scientific article published in 2006

Gene expression changes after heat shock of procyclic-form Trypanosoma brucei suggest that stress has a role in differentiation to mammalian-infective forms

article

Genetic manipulation of kinetoplastida

scientific article

Genetic nomenclature for Trypanosoma and Leishmania.

scientific article

Glycosome assembly in trypanosomes: variations in the acceptable degeneracy of a COOH-terminal microbody targeting signal

scientific article

Heat shock causes a decrease in polysomes and the appearance of stress granules in trypanosomes independently of eIF2(alpha) phosphorylation at Thr169

scientific article published on 19 August 2008

Identification of core components of the exon junction complex in trypanosomes

scientific article published on 5 April 2009

Impaired dimerization and trafficking of ESAG6 lacking a glycosyl-phosphatidylinositol anchor

scientific article published on 01 December 2003

Import of a DHFR hybrid protein into glycosomes in vivo is not inhibited by the folate-analogue aminopterin

scientific article published on February 1996

In vitro culture of freshly isolated Trypanosoma brucei brucei bloodstream forms results in gene copy-number changes

scientific article published in 2021

Interactions of CAF1-NOT complex components from Trypanosoma brucei

Is there a classical nonsense-mediated decay pathway in trypanosomes?

scientific article

Knockdown of asparagine synthetase A renders Trypanosoma brucei auxotrophic to asparagine

scientific article (publication date: 2013)

Life without transcriptional control? From fly to man and back again

scientific article

Mechanisms of developmental regulation in Trypanosoma brucei: a polypyrimidine tract in the 3'-untranslated region of a surface protein mRNA affects RNA abundance and translation.

scientific article

Messenger RNA processing sites in Trypanosoma brucei.

scientific article published in October 2005

Metabolic selection of a homologous recombination-mediated gene loss protects Trypanosoma brucei from ROS production by glycosomal fumarate reductase

scientific article published on 01 January 2021

Methods to determine the transcriptomes of trypanosomes in mixtures with mammalian cells: the effects of parasite purification and selective cDNA amplification

scientific article

Mitochondrial carrier family inventory of Trypanosoma brucei brucei: Identification, expression and subcellular localisation.

scientific article

Networks of gene expression regulation in Trypanosoma brucei.

scientific article published on July 2014

Overexpression of the putative thiol conjugate transporter TbMRPA causes melarsoprol resistance in Trypanosoma brucei

scientific article published in March 2002

PARP gene expression: control at many levels

scientific article published on March 1998

Post-transcriptional control of PARP gene expression

scientific article published on April 1996

Post-transcriptional control of hsp70 mRNA in Trypanosoma brucei

scientific article published on 01 February 1996

Post-transcriptional regulation of gene expression in trypanosomes and leishmanias

scientific article published on 19 July 2007

Post-transcriptional regulation of the trypanosome heat shock response by a zinc finger protein

scientific article

Processing of a phosphoglycerate kinase reporter mRNA in Trypanosoma brucei is not coupled to transcription by RNA polymerase II.

scientific article published on 2 April 2010

Proteins and lipids of glycosomal membranes from Leishmania tarentolae and Trypanosoma brucei

scientific article published on 29 January 2013

RNA interference in trypanosomes transfected with sense and antisense plasmids

scientific article published on 01 April 2002

RNA-binding domain proteins in Kinetoplastids: a comparative analysis

scientific article

Recognition of a peroxisomal tripeptide entry signal by the glycosomes of Trypanosoma brucei

scientific article published on April 1991

Regulated expression of glycosomal phosphoglycerate kinase in Trypanosoma brucei

scientific article published in December 2006

Regulating a Post-Transcriptional Regulator: Protein Phosphorylation, Degradation and Translational Blockage in Control of the Trypanosome Stress-Response RNA-Binding Protein ZC3H11

scientific article

Regulation of a transmembrane protein gene family by the small RNA-binding proteins TbUBP1 and TbUBP2.

scientific article published on 5 October 2007

Regulation of an amino acid transporter mRNA in Trypanosoma brucei

scientific article published on 2 October 2007

Regulation of gene expression in trypanosomatids: living with polycistronic transcription

scientific article published on 05 June 2019

Repetitive elements in parasitic protozoa

scientific article

Role of 3'-untranslated regions in the regulation of hexose transporter mRNAs in Trypanosoma brucei

scientific article published in December 1995

Roles of a Trypanosoma brucei 5'->3' exoribonuclease homolog in mRNA degradation

scientific article

Roles of the Pumilio domain protein PUF3 in Trypanosoma brucei growth and differentiation

scientific article published on 09 June 2020

Roles of triosephosphate isomerase and aerobic metabolism in Trypanosoma brucei

scientific article

SUMOylation in Trypanosoma brucei

scientific article published on 8 October 2013

Small trypanosome RNA-binding proteins TbUBP1 and TbUBP2 influence expression of F-box protein mRNAs in bloodstream trypanosomes

scientific article published on 14 September 2007

Stress susceptibility in Trypanosoma brucei lacking the RNA-binding protein ZC3H30

scientific article published on 01 October 2018

Structure of a regulatory 3' untranslated region from Trypanosoma brucei

scientific article published in December 1999

Substrate specificity, localization, and essential role of the glutathione peroxidase-type tryparedoxin peroxidases in Trypanosoma brucei

scientific article published on 21 January 2005

TbMP81 is required for RNA editing in Trypanosoma brucei

scientific article published on April 2002

Testing Promoter Activity in the Trypanosome Genome: Isolation of a Metacyclic-Type VSG Promoter, and Unexpected Insights into RNA Polymerase II Transcription

article by M McAndrew et al published September 1998 in Experimental Parasitology

Tests of heterologous promoters and intergenic regions in Leishmania major

scientific article

The 3'-untranslated regions from the Trypanosoma brucei phosphoglycerate kinase-encoding genes mediate developmental regulation

scientific article

The CAF1-NOT complex of trypanosomes

scientific article published on 02 January 2014

The EIF4E1-4EIP cap-binding complex of Trypanosoma brucei interacts with the terminal uridylyl transferase TUT3

scientific article published on 22 November 2021

The Exosomes of Trypanosomes and Other Protists ⬇️

scientific article published on 01 January 2011

The F-box protein CFB2 is required for cytokinesis of bloodstream-form Trypanosoma brucei

scientific article

The Leishmania tarentolae exosome: Purification and structural analysis by electron microscopy

article

The PARP promoter of Trypanosoma brucei is developmentally regulated in a chromosomal context.

scientific article published on April 1996

The RNA helicase DHH1 is central to the correct expression of many developmentally regulated mRNAs in trypanosomes

scientific article

The RNA-associated MKT1 and MKT1L form alternative PBP1-containing complexes in Trypanosoma brucei

scientific article published on 12 June 2020

The RNA-binding protein RBP10 controls a regulatory cascade that defines bloodstream-form trypanosome identity

The Trypanosoma brucei CCCH zinc finger proteins ZC3H12 and ZC3H13.

scientific article

The Trypanosoma brucei zinc finger protein ZC3H18 is involved in differentiation

scientific article published on 24 February 2011

The antioxidant systems in Toxoplasma gondii and the role of cytosolic catalase in defence against oxidative injury

scientific article published on January 2004

The antioxidant systems inToxoplasma gondiiand the role of cytosolic catalase in defence against oxidative injury

scientific article published in 2005

The cell biology of disease

scientific article published on 01 February 1995

The cell cycle regulated transcriptome of Trypanosoma brucei

scientific article

The coatomer of Trypanosoma brucei

scientific article published in June 2001

The expression level determines the surface distribution of the transferrin receptor in Trypanosoma brucei

scientific article published on January 2003

The genome of the kinetoplastid parasite, Leishmania major

scientific article

The miRNA and mRNA Signatures of Peripheral Blood Cells in Humans Infected with Trypanosoma brucei gambiense

scientific article

The regulation of trypanosome gene expression by RNA-binding proteins

scientific article

The role of Trypanosoma brucei MRPA in melarsoprol susceptibility

scientific article published on 18 November 2005

The role of deadenylation in the degradation of unstable mRNAs in trypanosomes

scientific article published on 13 July 2009

The role of the 5'-3' exoribonuclease XRNA in transcriptome-wide mRNA degradation

scientific article published on 26 September 2011

The role of the zinc finger protein ZC3H32 in bloodstream-form Trypanosoma brucei

scientific article

The roles of 3'-exoribonucleases and the exosome in trypanosome mRNA degradation

scientific article published on 22 May 2013

The roles of intersubunit interactions in exosome stability

scientific article published on 23 June 2003

The silicon trypanosome.

scientific article published on 06 May 2010

The silicon trypanosome: a test case of iterative model extension in systems biology

scientific article published on January 2014

The subcellular localisation of trypanosome RRP6 and its association with the exosome

scientific article published on 7 November 2006

The suppressive cap-binding complex factor 4EIP is required for normal differentiation

The suppressive cap-binding-complex factor 4EIP is required for normal differentiation

The transcriptomes of Trypanosoma brucei Lister 427 and TREU927 bloodstream and procyclic trypomastigotes

scientific article published in February 2005

The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing

scientific article published on 25 September 2018

The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing

The trypanosome Pumilio domain protein PUF5.

scientific article

The trypanosome Pumilio-domain protein PUF7 associates with a nuclear cyclophilin and is involved in ribosomal RNA maturation

scientific article published on 12 February 2010

The zinc finger proteins ZC3H20 and ZC3H21 stabilise mRNAs encoding membrane proteins and mitochondrial proteins in insect-form Trypanosoma brucei.

scientific article published in February 2020

Transcription of 'inactive' expression sites in African trypanosomes leads to expression of multiple transferrin receptor RNAs in bloodstream forms

scientific article published in June 1999

Transcriptome analysis of differentiating trypanosomes reveals the existence of multiple post-transcriptional regulons

scientific article

Transcriptomes of Trypanosoma brucei rhodesiense from sleeping sickness patients, rodents and culture: Effects of strain, growth conditions and RNA preparation methods.

scientific article published on 23 February 2018

Translation Regulation and RNA Granule Formation after Heat Shock of Procyclic Form Trypanosoma brucei: Many Heat-Induced mRNAs Are also Increased during Differentiation to Mammalian-Infective Forms

scientific article

Trypanosoma brucei PUF9 regulates mRNAs for proteins involved in replicative processes over the cell cycle

scientific article published on 28 August 2009

Trypanosome CNOT10 is essential for the integrity of the NOT deadenylase complex and for degradation of many mRNAs

scientific article published on 4 December 2012

Trypanosome MKT1 and the RNA-binding protein ZC3H11: interactions and potential roles in post-transcriptional regulatory networks

scientific article

Trypanosome MTR4 is involved in rRNA processing

scientific article published on 16 October 2007

Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress

scientific article (publication date: February 2000)

Vectors for inducible expression of toxic gene products in bloodstream and procyclic Trypanosoma brucei

article

Why do we need standard genetic nomenclature for parasite genes and gene products?

scientific article published in February 2000

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