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List of works by Sébastien Roger

A P2X7 receptor antagonist reverses behavioural alterations, microglial activation and neuroendocrine dysregulation in an unpredictable chronic mild stress (UCMS) model of depression in mice

scientific article published on 10 July 2018

ATP-activated P2X7 receptor in the pathophysiology of mood disorders and as an emerging target for the development of novel antidepressant therapeutics. ⬇️

scientific article published on 14 February 2018

ATP-induced Ca(2+)-signalling mechanisms in the regulation of mesenchymal stem cell migration ⬇️

scientific article

Activation of TRPV2 and BKCa channels by the LL-37 enantiomers stimulates calcium entry and migration of cancer cells

scientific article published on 16 March 2016

Anthraquinone emodin inhibits human cancer cell invasiveness by antagonizing P2X7 receptors

article published in 2013

Beneficial effects of omega-3 long-chain fatty acids in breast cancer and cardiovascular diseases: voltage-gated sodium channels as a common feature?

scientific article published on 16 February 2010

C-terminal calmodulin-binding motif differentially controls human and rat P2X7 receptor current facilitation

scientific article published on 8 April 2010

Carcinoma-specific expression of P2Y11 receptor and its contribution in ATP-induced purinergic signalling and cell migration in human hepatocellular carcinoma cells ⬇️

scientific article

Cellular acidification as a new approach to cancer treatment and to the understanding and therapeutics of neurodegenerative diseases.

scientific article published on 10 February 2017

Description and role in proliferation of iberiotoxin-sensitive currents in different human mammary epithelial normal and cancerous cells

scientific article

Dietary long-chain omega-3 fatty acids of marine origin: a comparison of their protective effects on coronary heart disease and breast cancers.

scientific article

Discovery and evaluation of nNav1.5 sodium channel blockers with potent cell invasion inhibitory activity in breast cancer cells

scientific article published on 3 April 2018

Effect of ultrasound-activated microbubbles on the cell electrophysiological properties.

scientific article published on January 2007

Facilitation of P2X7 receptor currents and membrane blebbing via constitutive and dynamic calmodulin binding.

scientific article

How do voltage-gated sodium channels enhance migration and invasiveness in cancer cells?

scientific article published on 25 April 2015

Hypoxia/Reoxygenation Inhibits P2Y11 Receptor Expression and Its Immunosuppressive Activity in Human Dendritic Cells.

scientific article published on 15 June 2015

Identification of SK3 channel as a new mediator of breast cancer cell migration

scientific article published on November 2006

Immature human dendritic cells enhance their migration through KCa3.1 channel activation.

scientific article published on 4 March 2016

Influence of the whole-cell patch-clamp configuration on electrophysiological properties of the voltage-dependent sodium current expressed in MDA-MB-231 breast cancer cells

scientific article published on 31 October 2003

Involvement of a novel fast inward sodium current in the invasion capacity of a breast cancer cell line

scientific article published on October 2003

Metabolic reprogramming in cancer cells, consequences on pH and tumour progression: Integrated therapeutic perspectives with dietary lipids as adjuvant to anticancer treatment

scientific article published on 17 March 2017

Na+ /H+ exchanger type-1: a shepherd for cellular transhumance

scientific article published on 26 December 2018

Navβ4: a metastasis suppressor and a new biomarker of aggressive cancers

scientific article published in June 2017

P2X(7) receptor activation enhances SK3 channels- and cystein cathepsin-dependent cancer cells invasiveness

scientific article published on 17 January 2011

P2X7 Receptor Promotes Mouse Mammary Cancer Cell Invasiveness and Tumour Progression, and Is a Target for Anticancer Treatment

scientific article published on 19 August 2020

P2X7 receptor antagonism in the treatment of cancers ⬇️

scientific article published on May 27, 2011

PPARβ mRNA expression, reduced by n−3 PUFA diet in mammary tumor, controls breast cancer cell growth ⬇️

scientific article published on July 30, 2013

Peroxidation of docosahexaenoic acid is responsible for its effects on I TO and I SS in rat ventricular myocytes

scientific article published on June 2003

Phosphorylation of NHERF1 S279 and S301 differentially regulates breast cancer cell phenotype and metastatic organotropism

scientific article published on 13 October 2018

Purinergic and Store-Operated Ca(2+) Signaling Mechanisms in Mesenchymal Stem Cells and Their Roles in ATP-Induced Stimulation of Cell Migration ⬇️

scientific article published in April 2016

Ranolazine inhibits NaV1.5-mediated breast cancer cell invasiveness and lung colonization

scientific article

Rock inhibition promotes NaV1.5 sodium channel-dependent SW620 colon cancer cell invasiveness

scientific article published on 07 August 2020

SCN4B acts as a metastasis-suppressor gene preventing hyperactivation of cell migration in breast cancer

scientific article published on 05 December 2016

Single nucleotide polymorphisms that were identified in affective mood disorders affect ATP-activated P2X7 receptor functions

scientific article

Sodium Channel Nav1.5 Controls Epithelial-to-Mesenchymal Transition and Invasiveness in Breast Cancer Cells Through its Regulation by the Salt-Inducible Kinase-1

scientific article published on 09 December 2019

Suppression of PPARβ, and DHA treatment, inhibit NaV1.5 and NHE-1 pro-invasive activities.

scientific article

The 20th ion channel meeting: September 2009, France

scientific article published on 22 July 2010

The Defibrillation Conundrum: New Insights into the Mechanisms of Shock-Related Myocardial Injury Sustained from a Life-Saving Therapy

scientific article published in 2021

The SK3/K(Ca)2.3 potassium channel is a new cellular target for edelfosine.

scientific article

The activation of P2Y2 receptors increases MCF-7 breast cancer cells migration through the MEK-ERK1/2 signalling pathway.

scientific article published on 3 January 2014

Understanding the roles of the P2X7 receptor in solid tumour progression and therapeutic perspectives ⬇️

scientific article

Usefulness of confocal laser endomicroscopy for predicting postoperative recurrence in patients with Crohn's disease: a pilot study

scientific article published on 05 March 2019

Voltage-gated Sodium Channel Activity Promotes Cysteine Cathepsin-dependent Invasiveness and Colony Growth of Human Cancer Cells.

scientific article published on 28 January 2009

Voltage-gated sodium channels and cancer: is excitability their primary role?

scientific article (publication date: 2015)

Voltage-gated sodium channels: new targets in cancer therapy?

scientific article published on January 2006

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