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List of works by Kenneth L. Tyler

A brain slice culture model of viral encephalitis reveals an innate CNS cytokine response profile and the therapeutic potential of caspase inhibition

scientific article

A herpes simplex virus DNA polymerase mutation that specifically attenuates neurovirulence in mice

scientific article

Activation of innate immune responses in the central nervous system during reovirus myelitis

scientific article published on 23 May 2012

Activation of intrinsic immune responses and microglial phagocytosis in an ex vivo spinal cord slice culture model of West Nile virus infection

scientific article published on 27 August 2014

Acute arcuate fiber demyelinating encephalopathy following Epstein-Barr virus infection

scientific article

An 85-year-old man with chronic lymphocytic leukemia and altered mental status

scientific article published in February 2007

Apoptosis in animal models of virus-induced disease

scientific article (publication date: February 2009)

Bell's palsy--is glucocorticoid treatment enough?

scientific article published in October 2007

COMMENTARY: Gibbs CJ Jr, Amyx HL, Bacote A, Masters CL, Gajdusek DC. Oral transmission of kuru, Creutzfeldt-Jakob disease, and scrapie to nonhuman primates. J Infect Dis 1980; 142:205-208.

scientific article published in August 2004

CSF findings in 250 patients with serologically confirmed West Nile virus meningitis and encephalitis.

scientific article

Cardiac cell-specific apoptotic and cytokine responses to reovirus infection: determinants of myocarditic phenotype

scientific article published on 03 March 2009

Caspase 8-dependent sensitization of cancer cells to TRAIL-induced apoptosis following reovirus-infection

scientific article

Caspase inhibition protects against reovirus-induced myocardial injury in vitro and in vivo

scientific article published on October 2004

Caspase-3 activation is required for reovirus-induced encephalitis in vivo

scientific article

Central nervous system apoptosis in human herpes simplex virus and cytomegalovirus encephalitis

scientific article published on 11 November 2002

Cerebral amyloid angiopathy with multiple intracerebral hemorrhages. Case report

scientific article published in August 1982

Colorado Surveillance Program for Chronic Wasting Disease Transmission to Humans

article

Contemporary circulating enterovirus D68 strains show differential viral entry and replication in human neuronal cells

Creutzfeldt–Jakob Disease

scientific article published on 01 February 2003

Current developments in understanding of West Nile virus central nervous system disease

scientific article published on June 2014

Daxx upregulation within the cytoplasm of reovirus-infected cells is mediated by interferon and contributes to apoptosis

scientific article published on 9 January 2013

Death receptor-mediated apoptotic signaling is activated in the brain following infection with West Nile virus in the absence of a peripheral immune response

scientific article

Detection of reovirus RNA in hepatobiliary tissues from patients with extrahepatic biliary atresia and choledochal cysts

scientific article published in June 1998

Disrupted glutamate transporter expression in the spinal cord with acute flaccid paralysis caused by West Nile virus infection

scientific article

Does Toll-like receptor 3 play a biological role in virus infections?

scientific article published in May 2004

Dual infections of the central nervous system with Epstein-Barr virus

scientific article published on 10 December 2004

Elevated CSF Cytokines in the Jarisch-Herxheimer Reaction of General Paresis ⬇️

scientific article published on August 1, 2013

Emerging viral infections of the central nervous system: part 1.

scientific article

Emerging viral infections of the central nervous system: part 2

scientific article

Eradication of Persistent Reovirus Infection from a B-Cell Hybridoma

article

Fingolimod and risk of varicella-zoster virus infection: back to the future with an old infection and a new drug

scientific article published in January 2015

Gene expression in the brain during reovirus encephalitis.

scientific article

Genes Induced by Reovirus Infection Have a Distinct Modular Cis-Regulatory Architecture

scientific article published on January 2005

Glutathione binding to the Bcl-2 homology-3 domain groove: a molecular basis for Bcl-2 antioxidant function at mitochondria

scientific article published on 9 August 2007

Herpesvirus infections of the nervous system.

scientific article published on February 2007

Hughlings Jackson: The Early Development of His Ideas on Epilepsy ⬇️

scientific article published on January 1, 1984

Human Herpesvirus 6 and Multiple Sclerosis: The Continuing Conundrum ⬇️

scientific article published on April 15, 2003

Human transmissible neurodegenerative diseases (prion diseases).

scientific article published on September 1992

Inhibition of NF-kappa B activity and cFLIP expression contribute to viral-induced apoptosis.

scientific article published on May 2005

Inhibition of Rac GTPase triggers a c-Jun- and Bim-dependent mitochondrial apoptotic cascade in cerebellar granule neurons

scientific article

Isolation and molecular characterization of a novel type 3 reovirus from a child with meningitis

scientific article published on 15 April 2004

Issues and updates in emerging neurologic viral infections.

scientific article published on July 2011

JNK regulates the release of proapoptotic mitochondrial factors in reovirus-infected cells.

scientific article published on December 2004

MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation

scientific article

MEKK1 regulates calpain-dependent proteolysis of focal adhesion proteins for rear-end detachment of migrating fibroblasts.

scientific article published on July 2003

Minocycline delays disease onset and mortality in reovirus encephalitis

scientific article

Molecular diagnosis of CNS viral infections

scientific article published in January 2005

Naturally acquired West Nile virus encephalomyelitis in transplant recipients: clinical, laboratory, diagnostic, and neuropathological features

scientific article

Neuro-intensive care of patients with acute CNS infections.

scientific article published on January 2012

Nonstructural protein sigma1s is a determinant of reovirus virulence and influences the kinetics and severity of apoptosis induction in the heart and central nervous system

scientific article

North American encephalitic arboviruses

scientific article

Novel Strategy for Treatment of Viral Central Nervous System Infection by Using a Cell-Permeating Inhibitor of c-Jun N-Terminal Kinase

scientific article

Origins and early descriptions of "Duchenne muscular dystrophy".

scientific article published in October 2003

PML therapy: “It's Déjà vu all over again” ⬇️

scientific article published on August 3, 2013

Polymerase chain reaction and the diagnosis of viral central nervous system diseases

scientific article published on 01 December 1994

Prednisolone--but not antiviral drugs--improves outcome in patients with Bell's palsy

scientific article published on 13 January 2009

Prions' travels--feces and transmission of prion diseases

scientific article published in July 2008

Profound cerebrospinal fluid pleocytosis and Froin's Syndrome secondary to widespread necrotizing vasculitis in an HIV-positive patient with varicella zoster virus encephalomyelitis

scientific article published in August 1998

Progressive multifocal leukoencephalopathy and apoptosis of infected oligodendrocytes in the central nervous system of patients with and without AIDS.

scientific article published on December 2002

Progressive multifocal leukoencephalopathy and relapsing-remitting multiple sclerosis: a comparative study

scientific article

Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis

scientific article

Progressive multifocal leukoencephalopathy, efalizumab, and immunosuppression: a cautionary tale for dermatologists.

scientific article published on August 2009

Progressive multifocal leukoencephalopathy: Can we reduce risk in patients receiving biological immunomodulatory therapies? ⬇️

scientific article published on September 1, 2010

Quantitative CSF PCR in Epstein-Barr virus infections of the central nervous system

scientific article published in November 2002

Recurrent dermatomal vesicular skin lesions: a clue to diagnosis of herpes simplex virus 2 meningitis

scientific article published in June 2003

Reduplicative paramnesia in Morvan's syndrome

scientific article published on 24 October 2007

Regional differences in viral growth and central nervous system injury correlate with apoptosis

scientific article published on May 2004

Reovirus activates transforming growth factor beta and bone morphogenetic protein signaling pathways in the central nervous system that contribute to neuronal survival following infection.

scientific article published on 11 March 2009

Reovirus infection of the CNS enhances iNOS expression in areas of virus-induced injury

scientific article

Reovirus-induced alteration in expression of apoptosis and DNA repair genes with potential roles in viral pathogenesis.

scientific article published on August 2003

Reovirus-induced alterations in gene expression related to cell cycle regulation.

scientific article

Reovirus-induced apoptosis is mediated by TRAIL

scientific article

Reovirus-induced apoptosis requires mitochondrial release of Smac/DIABLO and involves reduction of cellular inhibitor of apoptosis protein levels.

scientific article

Reovirus-induced neuronal apoptosis is mediated by caspase 3 and is associated with the activation of death receptors

scientific article published on October 2002

Serious Methodological Failures Concerning Presence of HSV DNA in Surgical Tissue From Human Epileptic Seizure Foci Detected by PCR

scientific article published on 01 July 1998

Signal transducer and activator of transcription-5 mediates neuronal apoptosis induced by inhibition of Rac GTPase activity

scientific article

Slice culture modeling of central nervous system (CNS) viral infection

scientific article published on January 2013

TRAIL and inhibitors of apoptosis are opposing determinants for NF-kappaB-dependent, genotoxin-induced apoptosis of cancer cells

scientific article published in January 2002

The 50th birthday of progressive multifocal leukoencephalopathy: New insights into pathogenesis

scientific article published on October 2008

The Role of Microglia during West Nile Virus Infection of the Central Nervous System

scientific article published on 28 August 2020

The proapoptotic Bcl-2 protein Bax plays an important role in the pathogenesis of reovirus encephalitis

scientific article

Two distinct phases of virus-induced nuclear factor kappa B regulation enhance tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in virus-infected cells

scientific article published on 13 March 2003

Type 3 reovirus neuroinvasion after intramuscular inoculation: viral genetic determinants of lethality and spinal cord infection

scientific article published on November 2002

Type I interferon signaling limits reoviral tropism within the brain and prevents lethal systemic infection

scientific article

West Nile and St. Louis encephalitis viruses

scientific article published on January 2014

West Nile virus encephalitis in America

scientific article published in June 2001

West Nile virus growth is independent of autophagy activation

scientific article

West Nile virus meningoencephalitis

scientific article

West Nile virus neuroinvasive disease

scientific article

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