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List of works by Jesús Oria-Hernández

Allosteric Interactions by p53 mRNA Govern HDM2 E3 Ubiquitin Ligase Specificity under Different Conditions

scientific article published on 23 May 2016

Biochemical Analysis of Two Single Mutants that Give Rise to a Polymorphic G6PD A-Double Mutant.

scientific article published on 26 October 2017

Cloning, Expression and Characterization of Recombinant, NADH Oxidase from Giardia lamblia

scientific article published on 19 December 2015

Cloning, expression, purification and characterization of his-tagged human glucose-6-phosphate dehydrogenase: a simplified method for protein yield.

scientific article published in October 2013

Determining the molecular mechanism of inactivation by chemical modification of triosephosphate isomerase from the human parasite Giardia lamblia: a study for antiparasitic drug design

scientific article published in September 2011

Dichotomic phylogenetic tree of the pyruvate kinase family: K+ -dependent and -independent enzymes

scientific article published on 11 August 2006

Disulfiram as a novel inactivator of Giardia lamblia triosephosphate isomerase with antigiardial potential.

scientific article

Giardial triosephosphate isomerase as possible target of the cytotoxic effect of omeprazole in Giardia lamblia

scientific article published on 15 September 2014

Kinetics of the thermal inactivation and aggregate formation of rabbit muscle pyruvate kinase in the presence of trehalose

scientific article published on 22 August 2009

Novel giardicidal compounds bearing proton pump inhibitor scaffold proceeding through triosephosphate isomerase inactivation

scientific article published on 10 August 2017

Proteomics: a tool to develop novel diagnostic methods and unravel molecular mechanisms of pediatric diseases

scientific article published on 24 May 2017

Pyruvate kinase revisited: the activating effect of K+.

scientific article

RNAi-Mediated Specific Gene Silencing as a Tool for the Discovery of New Drug Targets in Giardia lamblia; Evaluation Using the NADH Oxidase Gene.

scientific article published on 3 November 2017

Selectivity of pyruvate kinase for Na+ and K+ in water/dimethylsulfoxide mixtures

scientific article published in June 2003

Species-Specific Inactivation of Triosephosphate Isomerase from Trypanosoma brucei: Kinetic and Molecular Dynamics Studies.

scientific article

Structural and functional perturbation of Giardia lamblia triosephosphate isomerase by modification of a non-catalytic, non-conserved region

scientific article

Structural effects of protein aging: terminal marking by deamidation in human triosephosphate isomerase.

scientific article

Structure-based identification of a potential non-catalytic binding site for rational drug design in the fructose 1,6-biphosphate aldolase from Giardia lamblia

scientific article published on 13 August 2019

Synthesis of nitro(benzo)thiazole acetamides and in vitro antiprotozoal effect against amitochondriate parasites Giardia intestinalis and Trichomonas vaginalis

scientific article published on 10 March 2015

The E104D mutation increases the susceptibility of human triosephosphate isomerase to proteolysis. Asymmetric cleavage of the two monomers of the homodimeric enzyme.

scientific article

The active (ADHa) and inactive (ADHi) forms of the PQQ-alcohol dehydrogenase from Gluconacetobacter diazotrophicus differ in their respective oligomeric structures and redox state of their corresponding prosthetic groups

scientific article published on 06 January 2012

The stability of G6PD is affected by mutations with different clinical phenotypes.

scientific article